• 대한약침학회지
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• 제7권3호
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• pp.99-107
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• 2004

Background & Objective : Through the long-term clinical examination experience, interesting informations have been found and passed on to future scholars, enabling research and development without going through the same lengthy procedure, hoarding these precious information to be discovered and preserved as a contribution to Oriental Medical Science. Methods : Personal interviews with seventy-years-old practicing oriental medicine doctors and herbalists with more than 30 years of practice in Gangwon-do, Chungcheongbuk-do, Chungcheongnam-do, and Daejeon area from September to December 2002

• Bulletin of the Korean Chemical Society
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• 제28권8호
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• pp.1371-1374
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• 2007

The velocity auto-correlation (VAC) function of liquid argon in the Green-Kubo formula decays quickly within 5 ps to give a well-defined diffusion coefficient because the velocity is the property of each individual particle, whereas the stress (SAC) and heat-flux auto-correlation (HFAC) functions for shear viscosity and thermal conductivity have non-decaying, long-time tails because the stress and heat-flux appear as system properties. This problem can be overcome through N (number of particles)-fold improvement in the statistical accuracy, by considering the stress and the heat-flux of the system as properties of each particle and by deriving new Green-Kubo formulas for shear viscosity and thermal conductivity. The results obtained for the transport coefficients of liquid argon obtained are discussed.

• Communications for Statistical Applications and Methods
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• 제24권2호
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• pp.163-172
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• 2017

Economic sentiment is typically measured using ordinary response options. The University of Michigan and the United States Conference Board are two widely used major indexes that have separately established independent consumer sentiment indexes based on three-level ordinary response options: positive, neutral, and negative. Notwithstanding, limited attention has been paid to the structural differences in their built-in formulas, which are referred to the disparate micro scoring schemes applied to an individual question. This paper examines the structural difference of the two indexes and then addresses situations where one is more reliable than the other. Real data from business tendency surveys of the Organization for Economic Cooperation and Development are used to illustrate our points empirically. As a conclusion, it is stressed that the two indexes should be handled with care when applied to economic sentiment comparison studies.

• Genomics & Informatics
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• 제19권4호
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• pp.36.1-36.11
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• 2021

Predicting individual traits and diseases from genetic variants is critical to fulfilling the promise of personalized medicine. The genetic variants from genome-wide association studies (GWAS), including variants well below GWAS significance, can be aggregated into highly significant predictions across a wide range of complex traits and diseases. The recent arrival of large-sample public biobanks enables highly accurate polygenic predictions based on genetic variants across the whole genome. Various statistical methodologies and diverse computational tools have been introduced and developed to computed the polygenic risk score (PRS) more accurately. However, many researchers utilize PRS tools without a thorough understanding of the underlying model and how to specify the parameters for the best performance. It is advantageous to study the statistical models implemented in computational tools for PRS estimation and the formulas of parameters to be specified. Here, we review a variety of recent statistical methodologies and computational tools for PRS computation.

• 한국지리정보학회지
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• 제9권1호
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• pp.34-45
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• 2006

본 연구에서는 하천유역의 홍수유출을 계산하는데 있어 입력인자로 사용되는 도달시간과 저류상수등을 산정하는 데 있어 사용되는 경험식들의 조합에 따른 홍수유출량의 변화양상과 실제 관측된 유속을 이용하여 계산된 도달시간을 비교하였다. 계산된 도달시간과 첨두홍수량의 관계도 도달시간이 길어질수록 첨두홍수량은 낮아지는 결과를 나타내었다. 그러나 실측된 유속과 홍수량에서는 유량의 변화에도 유속을 이용한 도달시간은 크게 변화가 일어나지 않는 것으로 나타났다. 위천의 루사와 매미의 경우는 최적화된 모델의 도달시간이 실측된 모형의 도달시간보다 짧게 산정되었다. 모형을 이용하여 홍수량을 산정할 경우 입력 매개변수의 조합에 따라 홍수량을 산정한 결과 실측된 홍수량에 비하여 모형에 의해 계산된 홍수량의 경우 도달시간이 실측보다는 짧게 산정되는 것으로 분석되었다. 매미의 관측된 자료를 이용하여 평균유속으로 검토한 결과 루사와 매미의 경우는 위천의 용곡지점에 도달시간이 28시간 정도일 경우 홍수량과 하도의 유속과 수위가 거의 일치하는 것으로 분석되어 향후 홍수량 분석의 매개변수 산정에 참고가 될 수 있을 것이다.

• Journal of Nutrition and Health
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• 제27권5호
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• pp.429-441
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• 1994

The difference in lipid metabolism between breast-fed(BF) and formula-fed(FF) infants were studied in 31 Korean infants at 1, 2 and 3 months postpartum. The formulas had more total lipids(TL), triglycerides(TG) and phospholipids and less cholesterol(CHOL) and free fatty acids(FFA) than the breast milk. The milk consumption of the FF infants was significantly greater than that of the BF infants with a wide individual variation. As a result, the FF infants appeared to consume more TL, TG and PL and less CHOL and FFA than the BF infants during 3 months. The lipid contents of the breast milk tended to decrease in due course of lactation, therefore the intake of lipids of BF infants was reduced during the first three month of lactation. The plasma TG and CHOL levels of infants at 3 month were not significantly different between the BF and FF infants, but the PL level of the BF infants was higher then that of the FF infants. The plasma levels of TG and CHOL were not significantly correlated with the intakes of TL, TG, CHOL, PL and FFA, respectively. The PL level, however, was positively correlated with the intakes of CHOL and FFA, respectively and negatively correlated with PL intake as well as 18 : 2w6 fatty acid content of the breast milk or the formulas. The fecal weight and fecal loss of TL of the FF infants were greater than those of the BF infants during 3 months, however, apparent lipids digestibility was not significantly different between the BF and FF infants. The fecal excretions of CHOL and bile acids of FF infants were substantially higher than those of BF infants during 3 months. New sterol balance showed a particularly large difference between the BF and FF infants. The value of the net sterol balance of the BF infants was negative, but that of the FF infants was positive. This study shows that the consumption pattern of various lipid components of BF and FF infants were different as a result of different lipid compositions between breast milk and formula. The significantly lower sterol balance of the BF infants than the FF infants may have been derived from the unique dietary characteristic of breast milk.

• Kidney Research and Clinical Practice
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• 제37권4호
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• pp.373-383
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• 2018

Background: Several epidemiologic studies have suggested that the urine sodium excretion (USE) can be estimated in lieu of performing 24-hour urine collection. However, this method has not been verified in patients with chronic kidney disease (CKD) or in an interventional study. The purpose of this study was to evaluate the usefulness of estimating USE in a prospective low-salt diet education cohort (ESPECIAL). Methods: A new formula was developed on the basis of morning fasting urine samples from 228 CKD patients in the ESPECIAL cohort. This formula was compared to the previous four formulas in the prediction of 24-hour USE after treatment with olmesartan and low-salt diet education. Results: Most previously reported formulas had low predictability of the measured USE based on the ESPECIAL cohort. Only the Tanaka formula showed a small but significant bias (9.8 mEq/day, P < 0.05) with a low correlation (r = 0.34). In contrast, a new formula showed improved bias (-0.1 mEq/day) and correlation (r = 0.569) at baseline. This formula demonstrated no significant bias (-1.2 mEq/day) with the same correlation (r = 0.571) after 8 weeks of treatment with olmesartan. Intensive low-salt diet education elicited a significant decrease in the measured USE. However, none of the formulas predicted this change in the measured urine sodium after diet adjustment. Conclusion: We developed a more reliable formula for estimating the USE in CKD patients. Although estimating USE is applicable in an interventional study, it may be unsuitable for estimating the change of individual sodium intake in a low-salt intervention study.

• 한국수자원학회논문집
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• 제33권6호
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• pp.725-731
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• 2000

정지상조건에서 교각주위에 부설되는 보호공으로서 돌망태의 성능을 조사하기 위하여 실험이 수행되었다. 돌망태의 채움재료로서 사석의 크기는 돌망태의 시동에 영향을 주지않음이 밝혀졌다. 돌망태의 안정에 중요한 인자는 접근유속과 수심, 교각의 크기, 돌망태의 길이와 두께 등으로 조사 되었다. 같은량의 사석을 사용하는 경우 개체사석보다는 돌망태와 같이 집합체로서 안전성이 크게 증가된다. 돌망태의 길이가 시동에 특히 중요한 인자로서 길이를 증가하면 안전성이 증가한다. 또한 실험 결과는 교각주위 돌망태 크기의 결정식 유도에 사용되었다.

• Journal of Nutrition and Health
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• 제26권3호
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• pp.325-337
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• 1993

Korean breast-fed(BF) and formula-fed (FF) infants(n=31) were studied at their age of 1, 2 and 3 months to compare their intakes of energy, protein, lipid and lactose. Formulas had more energy, protein and lipid than breast milk, but the former had less lactose than the latter. The milk consumption of the FF infants was, however, greater than that of the BF infants with wide individual variation. As a result, the FF infants took in more energy, protein and lipid than the BF infants except lactose. The total daily caloric intakes(kcal/day) of the BF infants were 521.418 and 425 at their age of 1, 2 and 3 months respectively, and those of the FF infants were 676.752 and 723(at their age of 1, 2 and 3 months respectively). Daily protein intakes(g/days) of the BF infants were 9.5, 8.0 and 7.6 at their age of 1, 2 and 3 months respectively, and those of the FF infants were 13.9, 15.5 and 14.8(at their age of 1, 2 and 3 months respectively). The energy and protein of both the BF and the FF infants were deficient compared to the present Recommended Nutrient Allowances, and the deficiency of the BF infants was greater than that of the FF infants. But the energy intakes per kg of body weight of the FF infants at their age of 1 and 2 months were more than the present recommended energy allowances. And the protein intake per kg of body weight of the FF infant at the age of 1 month was the same as the present recommended protein allowances.

• Smart Structures and Systems
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• 제23권6호
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• pp.521-536
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• 2019

Using magnetorheological (MR) dampers in multiswitch open-loop control mode has been shown to be cost-effective for cable vibration mitigation. In this paper, a method for analyzing the damping performance of taut cables incorporating MR dampers in open-loop control mode is developed considering the effects of damping coefficient, damper stiffness, damper mass, and stiffness of the damper support. Making use of a three-element model of MR dampers and complex modal analysis, both numerical and asymptotic solutions are obtained. An analytical expression is obtained from the asymptotic solution to evaluate the equivalent damping ratio of the cable-damper system in the open-loop control mode. The individual and combined effects of the damping coefficient, damper stiffness, damper mass and stiffness of damper support on vibration control effectiveness are investigated in detail. The main thrust of the present study is to derive a general formula explicitly relating the normalized system damping ratio and the normalized damper parameters in consideration of all concerned effects, which can be easily used for the design of MR dampers to achieve optimal open-loop vibration control of taut cables.