• Title/Summary/Keyword: India Development

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p53 Codon 72 Polymorphism Interactions with Dietary and Tobacco Related Habits and Risk of Stomach Cancer in Mizoram, India

  • Malakar, Mridul;Devi, K. Rekha;Phukan, Rup Kumar;Kaur, Tanvir;Deka, Manab;Puia, Lalhriat;Sailo, Lalrinliana;Lalhmangaihi, T.;Barua, Debajit;Rajguru, Sanjib Kumar;Mahanta, Jagadish;Narain, Kanwar
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.717-723
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    • 2014
  • Background: This study was carried out to investigate the interaction of p53 codon 72 polymorphism, dietary and tobacco habits with reference to risk of stomach cancer in Mizoram, India. A total of 105 histologically confirmed stomach cancer cases and 210 age, sex and ethnicity matched healthy population controls were included in this study. Materials and Methods: The p53 codon 72 polymorphism was detected by PCR-RFLP and sequencing. H. pylori infection status was determined by ELISA. Information on various dietary and tobacco related habits was recorded with a standard questionnaire. Results: This study revealed that overall, the Pro/Pro genotype was significantly associated with a higher risk of stomach cancer (OR, 2.54; 95%CI, 1.01-6.40) as compared to the Arg/Arg genotype. In gender stratified analysis, the Pro/Pro genotype showed higher risk (OR, 7.50; 95%CI, 1.20-47.0) than the Arg/Arg genotype among females. Similarly, the Pro/Pro genotype demonstrated higher risk of stomach cancer (OR, 6.30; 95%CI, 1.41-28.2) among older people (>60 years). However, no such associations were observed in males and in individuals <60 years of age. Smoke dried fish and preserved meat (smoke dried/sun dried) consumers were at increased risk of stomach cancer (OR, 4.85; 95%CI, 1.91-12.3 and OR, 4.22; 95%CI, 1.46-12.2 respectively) as compared to non-consumers. Significant gene-environment interactions exist in terms of p53 codon 72 polymorphism and stomach cancer in Mizoram. Tobacco smokers with Pro/Pro and Arg/Pro genotypes were at higher risk of stomach cancer (OR, 16.2; 95%CI, 1.72-153.4 and OR, 9.45; 95%CI, 1.09-81.7 respectively) than the non-smokers Arg/Arg genotype carriers. The combination of tuibur user and Arg/Pro genotype also demonstrated an elevated risk association (OR, 4.76; 95%CI, 1.40-16.21). Conclusions: In conclusion, this study revealed that p53 codon 72 polymorphism and dietary and tobacco habit interactions influence stomach cancer development in Mizoram, India.

Institutional Repositories in BRICS Countries: A Study

  • Dhanavandan, S.;Tamizhchelvan, M.
    • International Journal of Knowledge Content Development & Technology
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    • v.5 no.1
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    • pp.33-47
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    • 2015
  • An institutional repository includes digital assets generated by academics, such as administrative documents, course notes, learning objects, or conference proceedings. It will provide a window that gives open access to improve the sponsoring institution's visibility and status. This paper discusses the growth and development of Institutional Repositories available in BRICS Countries. The relevant data was collected from the directory of OpenDOAR. Based on the data in OpenDOAR, 242 repositories are represented from BRICS countries. Among the 242, 84 (34.71%) repositories are from Brazil, 39 (16.12%) from China, 68 (28.10%) repositories from India, 22 (9.109%) repositories from Russia, and 29(11.98%) repositories from South Africa. Brazil has the largest number of records (11, 17,688) among BRICS Countries repositories.

PARABOLIC SOLAR CONCENTRATORS FOR COOKING, FOOD PROCESSING AND OTHER APPLICATIONS

  • Gadhia, Deepak
    • 한국신재생에너지학회:학술대회논문집
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    • 2006.11a
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    • pp.165-167
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    • 2006
  • On our return to India from Germany, we have worked on the development of parabolic solar concentrators with input and collaboration of German and Austrian inventors. We have gradually improved the solar technologies to include food processing based on inputs and feedback from users to fulfill their specific requirements. We will discuss the acceptability and commercialisation of various systems that we have successfully developed, their implications and their benefit. These success stories can work as multipliers. These concentrators can have various other applications. The Global Treaty Kyoto Protocol's CDM (Clean Development Mechanism) can result in a win-win situation for both developing and developed nations and the world environment at large - whereby developed nations get carbon credits by supporting renewable energy projects in developing nations. North-South dialogue and South-South dialogue can effectively foster global co-operation meaningfully to benefit People and environments ensuring sustainable development and protection of Our planet Earth, our only HOME!!!

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DEVELOPMENT OF UREA MOLASSES BLOCK AND ITS FIELD APPLICATION IN INDIA (A REVIEW)

  • Kunju, P.J. George
    • Asian-Australasian Journal of Animal Sciences
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    • v.1 no.4
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    • pp.233-239
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    • 1988
  • The base of Indian milk production is the millions of nondescript cows and buffaloes in rural areas, fed mainly on crop residues and agro-industrial wastes. The mainstay of the feeding system is straws and stovers. Therefore the approach to increase the fibrous residues utilisation for animal production was ideal and useful. The methods available for the above purpose were not found acceptable in rural areas owing to certain practical problems. The development of urea molasses block was, therefore aimed at solving the practical field problems. Urea Molasses Block has been developed as a feed supplement that can bring forth an effect of rumen manipulation thereby increase the conversion rate of feeds. The formula and process technology were thus developed. Before starting the mass production and popularisation the product was tested in controlled condition in farms and also in villages. Encouraged with the results the feed is now commercially manufactured under Indian Patent No. 156047.

Solar power and desalination plant for copper industry: improvised techniques

  • Sankar, D.;Deepa, N.;Rajagopal, S.;Karthik, K.M.
    • Advances in Energy Research
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    • v.3 no.1
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    • pp.59-70
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    • 2015
  • In India, continuous production of electricity and sweet/potable water from Solar power and desalination plant plays a major role in the industries. Particularly in Copper industry, Solar power adopts Solar field collector combined with thermal storage system and steam Boiler, Turbine & Generator (BTG) for electricity production and desalination plant adopts Reverse osmosis (RO) for sweet/potable water production which cannot be used for long hours of power generation and consistency of energy supply for industrial processes and power generation cannot be ensured. This paper presents an overview of enhanced technology for Solar power and Desalination plant for Copper industry making it continuous production of electricity and sweet/potable water. The conventional technology can be replaced with this proposed technique in the existing and upcoming industries.

Linking nuclear energy, human development and carbon emission in BRICS region: Do external debt and financial globalization protect the environment?

  • Sadiq, Muhammad;Shinwari, Riazullah;Usman, Muhammad;Ozturk, Ilhan;Maghyereh, Aktham Issa
    • Nuclear Engineering and Technology
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    • v.54 no.9
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    • pp.3299-3309
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    • 2022
  • Nuclear energy has the potential to play an influential role in energy transition efforts than is now anticipated by many countries. Realizing sustainable human development and reducing global climate crises will become more difficult without significantly increasing nuclear power. This paper aims to probe the role of nuclear energy, external debt, and financial globalization in sustaining human development and environmental conditions simultaneously in BRICS (Brazil, Russia, India, China, and South Africa) countries. This study applied a battery of second-generation estimation approaches over the period from 1990 to 2019. These methods are useful and robust to cross-countries dependencies, slope heterogeneity, parameters endogeneity, and serial correlation that are ignored in conventional approaches to generate more comprehensive and reliable estimates. The empirical findings indicate that nuclear energy and financial globalization contribute to human development, whereas external debt inhibits it. Similarly, financial globalization accelerates ecological deterioration, but nuclear energy and external debt promote environmental sustainability. Moreover, the study reveals bidirectional feedback causalities between human development, carbon emissions and nuclear energy consumption. The study offers useful policy guidance on accomplishing sustainable and inclusive development in BRICS countries.

Effects of forestry host plants, rearing seasons and their interaction on cocoon productivity of tropical tasar silkworm, Antheraea mylitta in uttarakhand

  • Bhatia, N.K.;Yousuf, Mohd.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.30 no.2
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    • pp.31-39
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    • 2015
  • Antheraea mylitta Drury (Lepidoptera: Saturniidae) is a commercial silk producing forest insect of India, but it has never been experimented in Uttarakhand state in spite of the huge availability of its forestry host plants. This is the first study on A. mylitta in Uttarakhand. The goal of this study is to introduce forest based commercial rearing of A. mylitta, in tropical forest areas of Uttarakhand to reduce poverty among forest dependent people. In current study, we assessed the effect of seven forest tree species, rearing seasons, and their interactions on cocoon productivity of Daba (bivoltine) ecorace of A. mylitta in the New Forest of FRI, Dehra Dun during 2012 and 2013 and collected the data that was analysed by two-way completely randomized block factorial design. Post HOC Tukey's HSD test was carried out to compare the homogeneous pairs of means. We also carried out Evaluation Index analysis to rank the tested forestry host plants for better growth and development of A. mylitta under the climatic condition of Uttarakhand. Analysis of variance indicated that cocoon yield of A. mylitta differed significantly between rearing seasons (DF=1, F=88.24, p<0.05) and host plants (DF 6, F= 368.63, p<0.05); however, their interactions were found insignificant (DF=6, F=0.99, p>0.05). In first rearing season of July-August, there was higher cocoon yield than the second season of September-November. Results indicated that Terminalia alata fed larvae showed significantly higher cocoon yield (164.11 cocoons/300 larvae); followed by, T. tomentosa (148.89 cocoons), T. arjuna (140.00 cocoons) and Lagerstroemia speciosa (129.47 cocoons) fed larvae. Whereas, Lagerstroemia tomentosa fed larvae that was used by the first time in India, showed lowest cocoon yield (48.81 cocoons), followed by T. chebula (72.53 cocoons) fed larvae. Cocoon yield of T. tomentosa and T. arjuna fed larvae of A. mylitta did not differ significantly with each other.

Study on Atmospheric Corrosion for Two Different Marine Environments in India

  • Saha, Jayanta Kumar
    • Corrosion Science and Technology
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    • v.6 no.3
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    • pp.120-127
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    • 2007
  • In any developing nation major investment goes for infrastructure and it is not exception in India. Good numbers of buildings, bridges, shopping malls, car parks etc. are coming up with steel for sustainable development. Thus protecting the structures from corrosion are the challenges faced by professionals for all types of steel structures. About 3% of GDP is accounted for loss due to corrosion. To combat this up to date corrosion map is called for as the country has wide variation of climatic zones with vastcoastline. Logically organic paint system can be prescribed based on the corrosion rate on bare steel with respect to environment. Present paper will emphasis on the study conducted on two types of structural steel coated with organic paint located in twomarine environment having been exposed for three years, Test coupons made from steels both bare and coated are deployed at two field stations having marine (Digha) and industrial marine (Channai) environments. Various tests like AC impedance DC corrosion, polarisation, salt spray test, $SO_2$ chamber and Raman spectroscopy were carried out both in laboratory on fresh as well as coupons collected from exposure sites. Rust formed on the bare and scribed coated coupons are investigated. It is found that normal marine environment at Digha exhibits higher corrosion rate than polluted marine environment in Channai. Rust analysis indicates formation of ${\propto}$-FeoOH protects or reduces corrosion rate at Channai and formation of non-protective ${\gamma}$-FeoOH increases corrosion rate at Digha. The slower corrosion rate in Channai than at Digha is attributed due to availability of $SO_2$, in the environment, which converts non‐protective rust ${\gamma}$-FeoOH to protective rust ${\propto}$-FeoOH. While comparing the damage on the coated panels it is found that low alloy structural steel provides less damage than plain carbon steel. From the experimentations a suitable paint system specification is drawn for identical environments for low medium and high durability.

Analysis of Land Use Pattern Change of Sub-Watershed -Focused on Moyar, India- (유역하류지역의 토지이용변화 분석 -인도 Moyar유역을 중심으로-)

  • Malini, Ponnusamy;Yeu, Yeon
    • Journal of Korean Society for Geospatial Information Science
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    • v.18 no.2
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    • pp.87-92
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    • 2010
  • Large pressure on the growing population has increased rapid change in the LULC (land use/land cover) patterns in the watershed area. Spatial distribution of LULC information and its changes are desirable for any effective planning, managing and monitoring activities. The aim of the study is to produce the 1,50,000 scaled LULC change map for the sub-watershed, Western Moyar, India using the multi-temporal satellite image dataset of IRS LISS III images for the year 1989, 1999, and 2002. About 9 classes are extracted using onscreen visual interpretation techniques for all the three years. The change detection analysis was performed using matrix method for period I (1989-1999) and period II (1999-2002). The study reveals that the changes noticed in period II (1999-2002) is comparatively more than period I (1989-1999), which is dynamic information to protect the sub-watershed area from the deterioration and paves the way to for the sustainable development.

Druggability for COVID-19: in silico discovery of potential drug compounds against nucleocapsid (N) protein of SARS-CoV-2

  • Ray, Manisha;Sarkar, Saurav;Rath, Surya Narayan
    • Genomics & Informatics
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    • v.18 no.4
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    • pp.43.1-43.13
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    • 2020
  • The coronavirus disease 2019 is a contagious disease and had caused havoc throughout the world by creating widespread mortality and morbidity. The unavailability of vaccines and proper antiviral drugs encourages the researchers to identify potential antiviral drugs to be used against the virus. The presence of RNA binding domain in the nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) could be a potential drug target, which serves multiple critical functions during the viral life cycle, especially the viral replication. Since vaccine development might take some time, the identification of a drug compound targeting viral replication might offer a solution for treatment. The study analyzed the phylogenetic relationship of N protein sequence divergence with other 49 coronavirus species and also identified the conserved regions according to protein families through conserved domain search. Good structural binding affinities of a few natural and/or synthetic phytocompounds or drugs against N protein were determined using the molecular docking approaches. The analyzed compounds presented the higher numbers of hydrogen bonds of selected chemicals supporting the drug-ability of these compounds. Among them, the established antiviral drug glycyrrhizic acid and the phytochemical theaflavin can be considered as possible drug compounds against target N protein of SARS-CoV-2 as they showed lower binding affinities. The findings of this study might lead to the development of a drug for the SARS-CoV-2 mediated disease and offer solution to treatment of SARS-CoV-2 infection.