• Title/Summary/Keyword: India

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Long-term complications after extrahepatic cyst excision for type IV-A choledochal cysts

  • Utpal Anand;Aaron George John;Rajeev Nayan Priyadarshi;Ramesh Kumar;Basant Narayan Singh;Kunal Parasar;Bindey Kumar
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.4
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    • pp.433-436
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    • 2023
  • Forty-five adults with type IV-A choledochal cysts (CDC) who underwent extrahepatic cyst excision from January 2013 to December 2021 were followed up for a median interval of 25 months (range, 2 to 10 years) to observe the long-term complications in the remaining intrahepatic cyst. Late complications in varying combinations were seen in 10 patients, which included cholangitis and/or intrahepatic stones in 9 patients, intrahepatic bile duct stenosis with stones in 2 patients, anastomotic stricture in 6 patients, and left lobar atrophy with intrahepatic stones in 3 patients. Out of 6 patients who required re-do hepaticojejunostomy (HJ), three patients had left lobe atrophy with patent HJ anastomosis and a recurrent attack of cholangitis on follow-up at 3, 8, and 10 years. Complications occur frequently after extrahepatic cyst excision for type IV-A CDC and require a long-term follow-up.

Clinico-pathological Profile of Lung Cancer at AIIMS: A Changing Paradigm in India

  • Malik, Prabhat Singh;Sharma, Mehar Chand;Mohanti, Bidhu Kalyan;Shukla, N.K.;Deo, S.V.S.;Mohan, Anant;Kumar, Guresh;Raina, Vinod
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.489-494
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    • 2013
  • Background: Lung cancer is one of the commonest and most lethal cancers throughout the world. The epidemiological and pathological profile varies among different ethnicities and geographical regions. At present adenocarcinoma is the commonest histological subtype of non-small cell lung cancer (NSCLC) in most of the Western and Asian countries. However, in India squamous cell carcinoma has been reported as the commonest histological type in most of the series. The aim of the study was to analyze the current clinico-pathological profile and survival of lung cancer at our centre. Materials and Methods: We analyzed 434 pathologically confirmed lung cancer cases registered at our centre over a period of three years. They were evaluated for their clinical and pathological profiles, treatment received and outcome. The available histology slides were reviewed by an independent reviewer. Results: Median age was 55 years with a male:female ratio of 4.6:1. Some 68% of patients were smokers. There were 85.3% NSCLC and 14.7% SCLC cases. Among NSCLCs, adenocarcinoma was the commonest histological subtype after the pathology review. Among NSCLC, 56.8% cases were of stage IV while among SCLC 71.8% cases had extensive stage disease. Some 29% of patients did not receive any anticancer treatment. The median overall and progression free survivals of the patients who received treatment were 12.8 and 7.8 months for NSCLC and 9.1 and 6.8 months for SCLC. Conclusions: This analysis suggests that adenocarcinoma may now be the commonest histological subtype also in India, provided a careful pathological review is done. Most of the patients present at advanced stage and outcome remains poor.

Chlorococcales (Chlorophyceae) of Eastern and North-eastern States of India

  • Jena, Mrutyunjay;Adhikary, Siba Prasad
    • ALGAE
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    • v.22 no.3
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    • pp.167-183
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    • 2007
  • Fifty-six taxa of chlorococcales were recorded from different water bodies of eastern and north-eastern states of India. These belong to 21 genera, e.g. Chlorococcum (1), Truebaria (1), Pediastrum (9), Hydrodictyon (1), Botrycoccus (1), Coenochloris (1), Radiococcus (1), Coenocystis (1), Oocystis (1), Glaucocystis (1), Chlorella (1), Kirchneria (2), Kirchnereilla (1) Ankistrodesmus (10), Coelastrum (3), Actinastrum (2), Tetrastrum (1), Crucigenia (1), Crucigeniella (1) Desmodesmus (6) and Scenedesmus (9). All these species were recorded first time from this region and out of these 16 species reported first from India.

LIGO-India: Beyond discovery of Gravitational waves.

  • Souradeep, Tarun
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.1
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    • pp.27.2-27.2
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    • 2017
  • The historic discovery of gravitational waves through direct detection by the LIGO observatories in the USA, in principle, opens up a new window for astronomy. In practice, however, the true launch of gravitational-wave astronomy will await the global array of LIGO like observatories including the planned LIGO-India observatory recently flagged off by the Union cabinet of India. I will review the momentous discovery, the potential of gravitational-wave astronomy and the promise of LIGO-India.

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Two Specie of Batrachospermum from Orissa State,Eastern India

  • Ratha, Sachitra Kumar;Adhikary, Siba Prasad
    • ALGAE
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    • v.24 no.2
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    • pp.61-66
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    • 2009
  • Two species of Batrachospermum, B, Iongiarticulatum Necchi and B. vagum (Roth) C. Agardh are reported from fastrunning streams of Orissa state, in eastern India. B. longiarticulatum, Previously known only from Brazil is a newrecord for lndia. This brings the number of Batrachospemum species known from India to 14.

Isolation of a Potent Mosquito Repellent from Vitex negundo L.: An Alternative Source of Rotundial

  • Amancharla, Praveen K.;Muthuraj, Patrick S.;Rao, Gottumukkala V.;Singh, Om V.
    • Natural Product Sciences
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    • v.5 no.2
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    • pp.104-106
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    • 1999
  • The chloroform fraction of the aqueous extract of the fresh leaves of Vitex negundo by bioactivity guided isolation yielded a pure compound, rotundial (1) which has shown potent mosquito repellent activity. Using spectral data (UV, IR, $^1H\;&\;^{13}C$ NMR and MS) its structure has been elucidated.

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Smart phone Buying Behaviour Among Youth in the Emerging Economies: A Study Conducted in India

  • Nair, Vinith Kumar;George, Babu P
    • The Journal of Economics, Marketing and Management
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    • v.4 no.2
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    • pp.33-47
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    • 2016
  • The second decade of the current century has witnessed a sharp rise in the total number of mobile users across the globe. Mobile device ownership rather defines our daily lives and even identities. India has emerged to become one of the largest markets for smartphones. India is an emerging economy with a lot of uniqueness: particularly, it has one of the most tech literate young consumers in the world and that its cultural fabric is extremely collective. This study looks into some issues related to the proliferation of smartphones among the Indian youth.

Mantle Cell Lymphoma: A North Indian Tertiary Care Centre Experience

  • Das, Chandan Krushna;Gogia, Ajay;Kumar, Lalit;Sharma, Atul;Sharma, Mehar Chand;Mallick, Saumya Ranjan
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.10
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    • pp.4583-4586
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    • 2016
  • Background: Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin's lymphoma, with a pathognomonic chromosomal translocation t (11;14). Prognosis is uniformly dismal but there is a paucity of information on MCL from India. Materials and methods: We retrospectively analysed clinicopathological information on all treated patients with MCL at our centre. STATA 14.0 was used for analysis. Survival was assessed by Kaplan-Meier analysis and the Cox's proportional hazards method. Statistical significance was defined as a P value of < 0.05. Results: Fifty-one patients with MCL were reviewed. The median age at presentation was 57.0 years. Extranodal involvement was seen in 39.0 (74.0%) while bone marrow positivity at presentation was found in 27.0 (54.0%). Initial treatment was chemotherapy with or without rituximab. Patients receiving rituximab-based therapy (n = 24) had 5-year progression-free survival (PFS) of 21.0 (88.0%), compared with 14.0 (61.0%) for those not receiving rituximab (n = 23, P = 0.036). Twenty-three patients were alive with a median follow-up of 20.7 months (range 2.5-89.2). PFS at 1 and 2 years was 51.0% and 27.0%, and overall survival (OS) 78.0% and 72.0%, respectively. Use of more than 2.0 lines of therapy, use of bendamustine-rituximab, and high TLC (>10,000.0/cu.mm) significantly affected PFS. Conclusions: In our experience, MCL patients from north India have an early age at presentation. When treated with regimens including rituximab results in an improved response rate and PFS. This study provided comprehensive insights into the treatment of MCL in a developing country.

Underutilization of Curative Treatment among Patients with Non Small Cell Lung Cancer: Experience from a Tertiary Care Centre in India

  • Malik, Prabhat Singh;Malik, Anita;Deo, Suryanarayana Venkata;Mohan, Anant;Mohanti, Bidhu Kalyan;Raina, Vinod
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2875-2878
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    • 2014
  • Background: Lung cancer is one of the commonest and most lethal cancers throughout the world. The majority of the patients present at advance stage and are not suitable for curative intent treatment. Even among patients with localized disease, there has been underutilization of curative treatment modalities. The aim of this study was to analyze the radical treatment utilization rates in patients with non small cell lung cancer (NSCLC) treated at our centre. Materials and Methods: We analyzed case records of 104 patients with a pathologically confirmed diagnosis of NSCLC having stage 1-3B disease who were treated at our centre over last 3 years, to assess the utilization of curative treatment modalities i.e. surgery or radical radiotherapy. Results: The median age of this cohort was 58 years. Out of 104 patients only 33 (31.7%) received curative intent treatment, 14 undergoing curative resection and 19 receiving radical doses of radiotherapy. The baseline characteristics of both the groups (with or without radical treatment) were not different. Major factors associated with underutilization with curative treatment were progressive disease or loss of follow up after chemotherapy and inappropriate use of TKI and/or palliative radiotherapy in patients with stage 1-3B disease. Patients who did not receive radical treatment had inferior PFS and OS than those who received radical treatment. Conclusions: In our practice we observed gross underutilization of curative intent treatment modalities in patients with NSCLCs which is associated with inferior survival.