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A Single-Chip CMOS Digitally Synthesized 0-35 MHz Agile Function Generator

  • Meenakarn, C.;Thanachayanont, A.
    • Proceedings of the IEEK Conference
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    • 2002.07c
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    • pp.1984-1987
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    • 2002
  • This paper describes the design and implementation of a single-chip digitally synthesized 0-35MHz agile function generator. The chip comprises an integrated direct digital synthesizer (DDS) with a 10-bit on- chip digital-to-analog converter (DAC) using an n-well single-poly triple-metal 0.5-$\mu\textrm{m}$ CMOS technology. The main features of the chip include maximum clock frequency of 100 MHz at 3.3-V supply voltage, 32-bit frequency tuning word resolution, 12-bit phase tuning word resolution, and an on-chip 10-bit DAC. The chip provides sinusoidal, ramp, saw-tooth, and random waveforms with phase and frequency modulation, and power-down function. At 100-MHz clock frequency, the chip covers a bandwidth from dc to 35 MHz in 0.0233-Hz frequency steps with 190-ns frequency switching speed. The complete chip occupies 12-mm$^2$die area and dissipates 0.4 W at 100-MHz clock frequency.

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Quality and antioxidant activity of ginseng seed processed by fermentation strains

  • Lee, Myung-Hee;Lee, Young-Chul;Kim, Sung-Soo;Hong, Hee-Do;Kim, Kyung-Tack
    • Journal of Ginseng Research
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    • v.39 no.2
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    • pp.178-182
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    • 2015
  • Background: Fermentation technology is widely used to alter the effective components of ginseng. This study was carried out to analyze the characteristics and antioxidant activity of ginseng seeds fermented by Bacillus, Lactobacillus, and Pediococcus strains. Methods: For ginseng seed fermentation, 1% of each strainwas inoculated on sterilized ginseng seeds and then incubated at $30^{\circ}C$ for 24 h in an incubator. Results: The total sugar content, acidic polysaccharides, and phenolic compounds, including p-coumaric acid, were higher in extracts of fermented ginseng seeds compared to a nonfermented control, and highest in extracts fermented with B. subtilis KFRI 1127. Fermentation led to higher antioxidant activity. The 2,2'-azine-bis-(3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical scavenging activity was higher in ginseng seeds fermented by Bacillus subtilis than by Lactobacillus and Pediococcus, but Superoxide dismutase (SOD) enzyme activity was higher in ginseng seeds fermented by Lactobacillus and Pediococcus. Conclusion: Antioxidant activities measured by ABTS and SOD were higher in fermented ginseng seeds compared to nonfermented ginseng seeds. These results may contribute to improving the antioxidant activity and quality of ginseng subjected to fermentation treatments.

Oocyte maturation under a biophoton generator improves preimplantation development of pig embryos derived by parthenogenesis and somatic cell nuclear transfer

  • Lee, DJoohyeong;Shin, Hyeji;Lee, Wonyou;Lee, Seung Tae;Lee, Geun-Shik;Hyun, Sang-Hwan;Lee, Eunsong
    • Korean Journal of Veterinary Research
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    • v.57 no.2
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    • pp.89-95
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    • 2017
  • This study was conducted to determine the effects of biophoton treatment during in vitro maturation (IVM) and/or in vitro culture (IVC) on oocyte maturation and embryonic development in pigs. An apparatus capable of generating homogeneous biophoton energy emissions was placed in an incubator. Initially, immature pig oocytes were matured in the biophoton-equipped incubator in medium 199 supplemented with cysteine, epidermal growth factor, insulin, and gonadotrophic hormones for 22 h, after which they were matured in hormone-free medium for an additional 22 hr. Next, IVM oocytes were induced for parthenogenesis (PA) or provided as cytoplasts for somatic cell nuclear transfer (SCNT). Treatment of oocytes with biophoton energy during IVM did not improve cumulus cell expansion, nuclear maturation, intraoocyte glutathione content, or mitochondrial distribution of oocytes. However, biophoton-treated oocytes showed higher (p < 0.05) blastocyst formation after PA than that in untreated oocytes (50.7% vs. 42.7%). In an additional experiment, SCNT embryos produced from biophoton-treated oocytes showed a greater (p < 0.05) number of cells in blastocysts (52.6 vs. 43.9) than that in untreated oocytes. Taken together, our results demonstrate that biophoton treatment during IVM improves developmental competence of PA- and SCNT-derived embryos.

Evaluation and Method of In Vitro Digestibility in Monogastric Animal Model (단위동물 모델에서 In vitro 소화율 측정과 평가)

  • Kang, Lyeongin;Kim, Jin Seon;Lee, Sung Sill;Chu, Gyo-Moon;Kim, Jin Wook
    • Journal of agriculture & life science
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    • v.53 no.2
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    • pp.15-26
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    • 2019
  • An in vitro digestibility methods have been developed to mimic an in vivo system in the past decades. Because the in vivo techniques cause high cost, intensive labor, longer research periods and ethnical problems. In this review, the digestive systems from stomach to large intestine of pig as a monogastric animal were addressed to understand an in vivo digestion. The innovative in vitro technique using the Daisy II incubator was performed and the in vitro ileal and fecal dry matter (DM) digestibility of corn, rice, wheat and barley was determined.

Roles of the Community Facilities for Foreigners as a Platform for Urban Globalization - Focused on the Seoul Global Centers - (도시 국제화를 위한 플랫폼으로서 외국인 커뮤니티 시설의 역할에 관한 연구 - 서울시 글로벌센터를 중심으로 -)

  • Choi, Sung-Jin;Han, Sun-Sheng
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.35 no.6
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    • pp.81-92
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    • 2019
  • Globalization has diversified ethnic composition thus increased the risk of conflicts and socio-political instability in global cities. However, still the status of community facility in a global city is unclear despite its critical role to build sustainable community in global era. In Seoul, as a reaction of globalization, 19 community facilities known as the 'Seoul Global Center' have been established since 2007 by Seoul Metropolitan Government. These facilities have started to provide basic foreigner services but been transformed to foreigner service hub with multiple functions in terms of a living, a business, a labour, etc. This study explores the role of the community facility for foreigners by using the Seoul Global Center as a case study, conducting a site observation, an interview(13 staff) and a questionnaire(148 visitors). The findings are the community facility functions as a 'global platform' in forms of a policy tool for implementing the urban globalization strategy, a mediator connecting foreign migrants with local communities, an applicant for successful settlement of foreign residents, an incubator that grows human and social capital, and a base for collecting and aggregating information on foreign migrants and forming new local identities.

Allelism and Molecular Marker Tests for Genic Male Sterility in Paprika Cultivars (파프리카 시판 품종에 대한 유전자적 웅성불임성의 대립성 및 분자표지의 유용성 검정)

  • Lee, Jun-Dae;Do, Jae-Wahng;Han, Jung-Heon;An, Chul-Geon;Kweon, Oh-Yoel;Kim, Yong-Kwon;Yoon, Jae-Bok
    • Horticultural Science & Technology
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    • v.29 no.2
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    • pp.130-134
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    • 2011
  • Paprika (Capsicum annuum L.), a colored bell-type sweet pepper, is one of the most important money making vegetable crops in Korea. The cultivation area, total production, and exports of paprika are gradually getting increased, but the paprika cultivars used in Korea are all imported. It was well-known that the genic male sterility (GMS) is the main way to produce paprika hybrid seeds. However, it is little known that how many and what kinds of ms genes are used for breeding of paprika $F_1$ varieties. In this study, eight paprika cultivars ('Special', 'Debla', 'Plenty', 'Fiero', 'Boogie', 'Fiesta', 'Derby', and 'Minibell'), popularly cultivated in Korea and three different genic male sterile lines ('GMSP', 'GMS3', and 'GMSK') were used. For allelism test among the $F_1$ cultivars, half diallel crosses were performed. The result demonstrated that the most of the GMS in paprika cultivars except for 'Minibell' were same allele. To identify which GMS gene(s) were used for paprika $F_1$ cultivars, top crosses between previously known GMS lines and the $F_1$ cultivars were performed. As a result, we found that the $ms_k$ and the $ms_p$ genes were alleles for the GMS of 'Minibell' and for the other cultivars, respectively. We also confirmed that the GMS gene identification using GMSK-CAPS marker linked to the $ms_k$ gene and the PmsM1-CAPS marker linked to the $ms_p$ gene in $F_2$ progenies of 'Minibell' and 'Fiesta' and 'Derby' cultivars, respectively. In addition, we developed the PmsM2-CAPS marker for 'Plenty', 'Fiero', and 'Boogie' cultivars. We expect that these markers will be very useful for breeding new maternal (male sterile) line of paprika.

Mitochondrial Distribution and Methionine Uptake in Fragmented and Non-fragmented Embryos Derived from Multi-pronuclei Zygotes in Human In Vitro Fertilization (IVF) Program (사람 다수정난자의 체외배양시 Fragmented Embryo와 Non-fragmented Embryo에서의 Methionine 유입량 및 미토콘드리아 분포양상의 비교)

  • Do, B.R.;Chung, M.K.;Chang, M.K.;Lee, K.A.;Ko, J.J.;Yoon, T.K.;Cha, K.Y.
    • Clinical and Experimental Reproductive Medicine
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    • v.22 no.3
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    • pp.279-285
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    • 1995
  • Despite the frequent incidence of embryo fragmentation in early human embryos, the reason of the embryo fragmentation has not been known yet. This study was conducted to investigate the histological difference(s) between fragmented (FR) and non-fragmented (NFR) human embryos focusing on comparison of mitochondrial distribution and protein synthesis. Multi-pronuclei zygotes (MPZ) such as three or more pronuclei containing in human in vitro fertilization and embryo transfer (IVF-ET) program were used for this study. MPZ were cultured in TCM-199 supplemented with 10% of human fetal cord serum (hFCS) in 5% $CO_2$ incubator at $37^{\circ}C$ for 24 hours. The cleaved embryos to 2-4 cells after 24 hours were grouped by their grade of fragmentation. Embryos were stained with Rhodamine123 (Rh123) and fluorescence was evaluated under the fluorescence microscope through PB 450-490 filter (Leitz). Regarding to protein synthesis during early human embryogenesis, there is no significant difference in the amount of synthetic proteins between FR and NFR embryos. Distribution of cytoplasmic organelles in embryos was evaluated by transmission electron microscope (TEM). The cytoplasmic distribution of mitochondria was different between FR and NFR embryos. The mitochondrial distribution was even in NFR, whereas severely aggregated in FR. It is not able to clarify in the present study whether this uneven mitochondrial distribution in FR embryo is the reason for embryo fragmentation or is the result from fragmentation. Physiological disparity related to the mitochondrial distribution may be one of the reasons for embryo fragmentation. Further studies should be addressed to investigate the physiological differences between FR and NFR embryos.

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The Effects of Management Traffic on the Local Call Processing Performance of ATM Switches Using Queue Network Models and Jackson's Theorem

  • Heo, Dong-Hyun;Chung, Sang-Wook;Lee, Gil-Haeng
    • ETRI Journal
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    • v.25 no.1
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    • pp.34-40
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    • 2003
  • This paper considers a TMN-based management system for the management of public ATM switching networks using a four-level hierarchical structure consisting of one network management system, several element management systems, and several agent-ATM switch pairs. Using Jackson's queuing model, we analyze the effects of one TMN command on the performance of the component ATM switch in processing local calls. The TMN command considered is the permanent virtual call connection. We analyze four performance measures of ATM switches- utilization, mean queue length and mean waiting time for the processor directly interfacing with the subscriber lines and trunks, and the call setup delay of the ATM switch- and compare the results with those from Jackson's queuing model.

Effects of the Ag Layer Embedded in NIZO Layers as Transparent Conducting Electrodes for Liquid Crystal Displays

  • Oh, Byeong-Yun;Heo, Gi-Seok
    • Transactions on Electrical and Electronic Materials
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    • v.17 no.1
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    • pp.33-36
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    • 2016
  • In the present work, a Ni-doped indium zinc oxide (NIZO) film and its multilayers with Ag layers were investigated as transparent conducting electrodes for liquid crystal display (LCD) applications, as a substitute for indium tin oxide (ITO) electrodes. By interposing the Ag layer between the NIZO layers, the loss of the optical transmittance occurred; however, the Ag layer brought enhancement of electrical sheet resistance to the NIZO/Ag/NIZO multilayer electrode. The twisted nematic cell based on the NIZO/Ag/NIZO multilayer electrode exhibited superior electro-optical characteristics than those based on single NIZO electrode and was competitive compared to those based on the conventional ITO electrode. An LCD-based NIZO/Ag/NIZO multilayer electrode may allow new approaches to conventional ITO electrodes in display technology.

Dot Idea (.IDEA): A New Concept for an Incubation Program and Open Innovation Based on User Needs

  • Maldaner, Luis Felipe;Simon, Luisa;Aranha, Carlos Eduardo de Souza
    • World Technopolis Review
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    • v.7 no.2
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    • pp.82-96
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    • 2018
  • This paper discussed the application process of the Dot Idea program. The Dot Idea program is an incubation and open innovation program co-created by Unitec, an incubator at Tecnosinos Tech Park, and an SAP innovation team. The main objective of this study was to cover an existing gap in the literature regarding the practical application of an open innovation methodology. Many companies seek interaction with external parties to enable advancement toward identified innovation opportunities. Technology clusters, parks, and incubators have played an important role in promoting connections and interaction. Consequently, the Dot Idea program emerged as a result of a joint effort to create a program using a design science research methodology aiming to foster new businesses and strengthen Brazil and Latin America as a hub to develop new solutions for traditional organizations. In regards to lessons learned, the Dot.health trial had some success but also experienced difficulties; these related to the relationships between startups and a hospital's internal teams, and startups' needs to be funded from the beginning in order to be fully dedicated to a project.