• Title/Summary/Keyword: Increased running speed

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The Effect of Acute Exhaustive Exercise and Long-term Endurance Exercise Training on the Protein Expression of Mn-SOD, HSP70 and PPAR-γ in the Heart of rats (일회성 탈진운동과 장기간 지구성 트레이닝이 심장근의 Mn-SOD, HSP70 및 PPAR-γ 단백질 발현에 미치는 영향)

  • Jun, Jongkui;Yoon, Aram;Lee, Kwangmoo;Lee, Wanglok
    • Korean Journal of Exercise Nutrition
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    • v.13 no.2
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    • pp.161-167
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    • 2009
  • The purpose of this study was to investigate whether two different exercises, acute exhaustive exercise and long-term endurance exercise training could affect to the expression of Mn-SOD, HSP70, and PPAR-γ protein in myocardium. The Wistar-Kyoto rats(n=24, 4 weeks) were used and randomly divided into 3 groups; endurance exercise training group (EET, n=8), acute exhaustive exercise group (AEE, n=8) or control group (CON, n=8). EET performed treadmill exercise for 12 weeks (5 days/week, 30~60 min/day). AEE exercised treadmill running (speed increased gradually to 14-26 m/min, 60 min ±10min) until exhausted when EET finished the program. Then, all the rats were sacrificed 48 hours rest at least after the last session of their own exercise program. Hearts were isolated and then the expression of Mn-SOD, HSP70, and PPAR-γ were analyzed by western blotting. One-way repeated ANOVA was used and p value under 0.05 was considered as statistical significance. The results were followed as; the expression of Mn-SOD of AEE was decreased compared with CON. However, the expression of Mn-SOD of EET was increased compared with CON. There was significant difference between AEE and EET in the expression of Mn-SOD. The expressions of HSP70 and PPAR-γ in the both AEE and EET were significantly increased compared with CON. In conclusion, acute exhaustive exercise might induce oxidative stress wheres endurance exercise training could ameliorate the oxidative conditions by increase of Mn-SOD, HSP70, and PPAR-γ. Therefore, we suggested that endurance exercise training could enhance the complementary antioxidant system and improve to prevent apoptosis. Further, a long-term moderat aerobic exercise program might play a important role in mitochondrial biogenesis in the heart.

The High-speed train model for reducing the micro-pressure wave in railway tunnel (고속철도 터널에서의 미기압파 저감을 위한 모형실험)

  • Jang, Yong-Jun;Park, Won-Hee;Kim, Seung-Tae
    • Proceedings of the KSR Conference
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    • 2007.11a
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    • pp.1330-1336
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    • 2007
  • The purpose of the study was to verify deduction of each coefficient necessary to analysis on micro-pressure waves and reliability of the analysis result. The tunnel running train model testing device used in the test was manufactured by scale of 1:60 and the study used a train model with ten cars long according to specifications of KTX model. The study applied tunnels with cross sections of $107.9m^3\;and\;95.1m^3$ and applied tunnel extensions with 1km, 0.75km and 0.5km. Also, the study tested train speed by changing it into 275, 300, 325 and 350km/h. The test device was a hydraulic launch system composed of a train model, a hydraulic launcher, a tunnel model and a brake. The study measured speed of a model trainby a speed sensor installed in the point of each 1.2m from the front of tunnel entrance and a pithead of tunnel exit and measured pressure change of internal tunnel continuously by installing pressure sensors in the entrance part of tunnel, in the middle part of tunnel and in the exit part of tunnel. As the result of the measurement, it was known that pressure slope of pressure wave happened in the entrance part of tunnel was increased by a nonlinear effect while spreading the tunnel or its pressure slope was reduced by diffusion. Also, the study compared and analyzed micro-pressure waves happened in the exit part of the tunnel by installing each kind of hoods in the entrance part of the tunnel to prevent reduction of micro-pressure waves.

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Large-scale 3D SSI Analysis using KIESSI-3D Program (KIESSI-3D 프로그램을 이용한 대형 3차원 SSI 해석)

  • Lee, Eun-Haeng;Kim, Jae-Min;Seo, Choon-Gyo
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.26 no.6
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    • pp.439-445
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    • 2013
  • The soil-structure interaction(SSI) effect should be considered to accurately assess the seismic response of structure constructed on soft soil site other than the hard bedrock. Recently, the demand of SSI analysis has increased due to strengthening of the regulatory guidelines of nuclear power plant such as the USNRC SRP 3.7.2. In this study an accuracy and running time of the KIESSI-3D program for large-scale 3D SSI analysis were investigated. The seismic SSI analysis using the KIESSI-3D program was performed for several examples of large-scale three-dimensional soil-structure interaction system. The analysis results were compared with those of the ACS/SASSI program. Good agreements in transfer functions at selected locations showd that KIESSI-3D yields accurate solution for large-scale SSI problem. Moreover, it was found that running speed of the KIESSI-3D for large-scale 3D SSI analysis is much faster than that of the ACS/SASSI about 30~2000 times.

Studies on the Maximal Oxygen Intake of the Korean - Part I. Accuracy of the Measurement of Maximal Oxygen Intake - (한국인(韓國人) 청년남여(靑年男女)의 최대산소섭취량(最大酸素攝取量)에 관(關)한 연구(硏究) - 제(第) I 편(篇) 최대효소섭취양(最大酸素攝取量) 측정치(測定値)의 변리도(變異度)에 관(關)하여 -)

  • Lee, Kee-Yong
    • The Korean Journal of Physiology
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    • v.1 no.1
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    • pp.83-90
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    • 1967
  • In order to evaluate the accuracy of the measurement of maximal oxygen intake (MOI), the MOI in seven subjects was determined 3 to 4 times in each individual. Following a 10 minute warm-up on treadmill (4.3 km/hr with 9 degree grade), the subject was asked to run at a speed of 8.73 km/hr on treadmill for a period of 3 minutes at a given grade which was elevated in a step-wise manner from zero to the level of exhaustion. Following a 3 minute run, the subject was allowed to rest for a period of 3 to 5 minutes. During each period of running, several cardio-pulmonary functions were determined and the range of variability for each measurement was computed. The oxygen consumption during the maximal work load was taken as the MOI. The results may be summarized as follows: (1) The minute volume, the oxygen consumption and the heart rate increased linearly until the grade was elevated to 9 degree above which these values were leveled off. (2) The minute volume and the heart rate during maximal exorcise were $87.4{\pm}8.10\;1/min\;and\;187{\pm}3.7$ per minute, respectively. (3) The maximal oxygen intake which corresponds to the oxygen consumption during maximal exercise was averaged to 3.04 1/min. (4) The coefficient of variance for the maximal oxygen intake was 6.32% while the corresponding values for the minute volume and the heart rate during maximal exercise were 5.22 and 2. 14%, respectively.

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Exercise Effects on the Atrophy of Denervated Muscles in Rat (흰쥐의 탈신경근 위축에 미치는 운동의 효과)

  • Yoon, Bum-Chul;Yu, Byong-Kyu;Lee, Myoung-Hwa
    • Physical Therapy Korea
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    • v.7 no.3
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    • pp.34-48
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    • 2000
  • The purpose of this study was to determine the effects of mild-intensity exercise training on the denervated muscle atrophy in the sciatic nerve injured rat. Thirty-six male Sprague-Dawley rats (250~300 g) were randomly assigned into three groups; sham-denervated group (n=8), denervated group (n=8), and denervated-exercised group (n=20). Exercise consisted of treadmill running at 20 m/min speed with 0% grade for 30 min/day. The animals were decapitated at the second and sixth weeks postcrush. Soleus and medial gastrocnemius were immediately excised to be weighed. Type I and II fibers of the muscles were differentiated by m-ATPase (pH 9.4) stain, and fiber diameters were evaluated. The results were as follows: 1) The weight of the soleus and medial gastrocnemius muscles showed a tendency to increase in both the denervation-exercised groups compared to the denervated group. 2) In the 2-week denervation-exercised group, type II fiber diameter of soleus and type I fiber diameter of medial gastrocnemius were increased significantly compared to the denervated control group. 3) In the 6-week denervated-exercised group, type I fiber diameter of soleus and type II fiber diameter of medial gastrocnemius were hypertrophied significantly compared to sham-denervated group. The results of this study suggested that treadmill exercise partially prevented denervation atrophy in the soleus and medial gastrocnemius of the rat.

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A Study of Distribute Computing Performance Using a Convergence of Xeon-Phi Processor and Quantum ESPRESSO (퀀텀 에스프레소와 제온 파이 프로세서의 융합을 이용한 분산컴퓨팅 성능에 대한 연구)

  • Park, Young-Soo;Park, Koo-Rack;Kim, Dong-Hyun
    • Journal of the Korea Convergence Society
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    • v.7 no.5
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    • pp.15-21
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    • 2016
  • Recently the degree of integration of processor and developed rapidly. However, clock speed is not increased, a situation that increases the number of cores in the processor. In this paper, we analyze the performance of a typical Intel Xeon Phi of many core process used for the current operation accelerate. Utilizing the Quantum ESPRESSO, which was calculated using the FFTW library. By varying the number of ranks in MPI when running the benchmarks the performance Xeon Phi. The result shows a good performance in the handling of four job on one physical core. However, four or more to expand the number of MPI Rank is degraded. Through this convergence it was found to improve the performance of Quantum ESPRESSO. It is possible to check the hardware characteristics of the Xeon Phi.

Braking performance of working rail-mounted cranes under wind load

  • Jin, Hui;Chen, Da
    • Wind and Structures
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    • v.19 no.1
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    • pp.1-14
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    • 2014
  • Rail-mounted cranes can be easily damaged by a sudden gust of wind while working at a running speed, due to the large mass and high barycenter positions. In current designs, working rail-mounted cranes mainly depend on wheel braking torques to resist large wind load. Regular brakes, however, cannot satisfactorily stop the crane, which induces safety issues of cranes and hence leads to frequent crane accidents, especially in sudden gusts of wind. Therefore, it is necessary and important to study the braking performance of working rail mounted cranes under wind load. In this study, a simplified mechanical model was built to simulate the working rail mounted gantry crane, and dynamic analysis of the model was carried out to deduce braking performance equations that reflect the qualitative relations among braking time, braking distance, wind load, and braking torque. It was shown that, under constant braking torque, there existed inflection points on the curves of braking time and distance versus windforce. Both the braking time and the distance increased sharply when wind load exceeded the inflection point value, referred to as the threshold windforce. The braking performance of a 300 ton shipbuilding gantry crane was modeled and analyzed using multibody dynamics software ADAMS. The simulation results were fitted by quadratic curves to show the changes of braking time and distance versus windforce under various mount of braking torques. The threshold windforce could be obtained theoretically by taking derivative of fitted curves. Based on the fitted functional relationship between threshold windforce and braking torque, theoretical basis are provided to ensure a safe and rational design for crane wind-resistant braking systems.

Molecular Characterization and Expression Analysis of the Peroxisome Proliferator Activated Receptor Delta (PPARδ) Gene before and after Exercise in Horse

  • Cho, Hyun-Woo;Shin, Sangsu;Park, Jeong-Woong;Choi, Jae-Young;Kim, Nam-Young;Lee, Woon-Kyu;Lee, Hak-Kyo;Song, Ki-Duk;Cho, Byung-Wook
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.5
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    • pp.697-702
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    • 2015
  • While athletic abilities such as speed, endurance and recovery are important in the horse, genes related to these abilities have not been extensively investigated. Here, we characterized the horse peroxisome proliferator-activated receptor delta ($PPAR{\delta}$) gene and analyzed the expression of $PPAR{\delta}$ during exercise. $PPAR{\delta}$ is a known regulator of ${\beta}$-oxidation, muscle fiber transformation, and running endurance. Through evolutionary analysis using the synonymous and non-synonymous mutation ratio, it was revealed that positive selection occurred in the horse $PPAR{\delta}$ gene. Two important domains related to nuclear hormone receptors, C4 zinc finger and ligand binding domain, were also found to be conserved well in horse $PPAR{\delta}$. Horse $PPAR{\delta}$ was expressed ubiquitously in many tissues, but the expression level was various depending on the tissues. In the skeletal muscle, $PPAR{\delta}$ increased about 2.5 folds after 30 min of exercise. Unlike in muscle, the increase of $PPAR{\delta}$ expression was observed at 60 min but not 30 min of exercise in leukocytes. This finding might be useful for testing the endurance of horse using blood samples. Conclusively, the horse $PPAR{\delta}$ gene is evolutionarily conserved well and can be used as a biomarker of endurance in horse.

Using Cache Access History for Reducing False Conflicts in Signature-Based Eager Hardware Transactional Memory (시그니처 기반 이거 하드웨어 트랜잭셔널 메모리에서의 캐시 접근 이력을 이용한 거짓 충돌 감소)

  • Kang, Jinku;Lee, Inhwan
    • Journal of KIISE
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    • v.42 no.4
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    • pp.442-450
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    • 2015
  • This paper proposes a method for reducing false conflicts in signature-based eager hardware transactional memory (HTM). The method tracks the information on all cache blocks that are accessed by a transaction. If the information provides evidence that there are no conflicts for a given transactional request from another core, the method prevents the occurrence of a false conflict by forcing the HTM to ignore the decision based on the signature. The method is very effective in reducing false conflicts and the associated unnecessary transaction stalls and aborts, and can be used to improve the performance of the multicore processor that implements the signature-based eager HTM. When running the STAMP benchmark on a 16-core processor that implements the LogTM-SE, the increased speed (decrease in execution time) achieved with the use of the method is 20.6% on average.

The Geomorphic Changes of Sand-Beach Coasts by Human Impact in Byeonsan Peninsula, Southwest Korea (인간간섭에 따른 변산반도 사빈해안의 지형변화)

  • CHOI, Hoon;LEE, Min-Boo
    • Journal of The Geomorphological Association of Korea
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    • v.19 no.3
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    • pp.83-96
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    • 2012
  • The origins of beaches at Byeonsan Peninsular, as a pocket type, are classified to a sand barrier type and wave-cut type. The beaches had developed by the deposition of the silt and clay layers on the 10m height from sea level in the inner bay during climax era of postglacial transgression. At that time, some sands had blown toward the inland hills to form aeolian deposits. After postglacial sea-level stabilization, sometimes, there has been the negative budget of beach materials. Recently, beaches have been transformed by human impact such as construction of Saemangeum sea-wall, especially in the Byeonsan and Gosapo beaches being close to the sea-wall. So the speed of tidal currents become slower and comparatively depositoinal activity stronger. And the level of chemical weathering has been higher. In Byeonsan beach, the ratio of coarse sand decreased with higher ratio of finer materials and by beach erosion dissected runnels developed, running parallel to the coastline. In Gosapo beach, supply of suspended materials are increased through the Garyeok drainage gate, the sands tend to be finer.