• 한국자기공명학회논문지
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• 제19권2호
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• pp.74-82
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• 2015

Ryanodine receptor (RyR) is one of the two major $Ca^{2+}$ channels in membranes of intracellular $Ca^{2+}$ stores and is found in sarcoplasmic reticulum (SR), endoplasmic reticulum (ER). RyR1 is also the major calmodulin-binding protein of sarcoplasmic reticulum membranes. Residues 4064-4210 in the RyR1 polypeptide chain has similar primary sequence with calmodulin (CaM) and was designated as CaM-like domain (CaMLD). When expressed as a recombinant peptide, CaMLD showed several CaM-like properties in previous studies. Still, previous studies of CaMLD were focused on protein-protein interactions rather than its own properties. Here, we studied the expression of CaMLD and its sub-domains corresponding to each lobe of CaM in Escherichia coli. CaMLD could be obtained only as inclusion body, and it was refolded using urea solubilization followed by dialysis. Using spectroscopic approaches, such as NMR, circular dichroism, and gel filtration experiment, we found that the refolded CaMLD exists as nonspecific aggregate, even though it has alpha helical secondary structure. In comparison, the first half of CaMLD (R4061-4141) could be obtained as natively soluble protein with thioredoxin fusion. After the removal of the fusion tag, it exhibited folded and helical properties as shown by NMR and circular dichroism experiments. Its oligomeric status was different from CaMLD, existing as dimeric form in solution. However, the second half of the protein could not be obtained as soluble protein regardless of fusion tag. Based on these results, we believe that CaMLD, although similar to CaM in sequence, has quite different physicochemical properties and that the second half of the protein renders it the aggregative properties.

• 한국환경복원기술학회지
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• 제4권4호
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• pp.64-71
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• 2001

Treatment efficiency was examined of a pond-wetland system constructed for water quality conservation of Koheung Estuarine Lake over one year after its establishment in July 2000. The system is composed of primary and secondary ponds in series and six wetland cells in parallel. Cattails (Typha angustiflora) were planted in three wetland cells and common reeds (Phragmites australis) in three other cells. Water pumped from Sinyang Stream flowing into the Lake was funneled into primary pond whose effluent was discharged into secondary pond by gravity flow. Effluent from secondary pond was distributed into each wetland cell. SS, $BOD_5$, T-N, and T-P concentrations in influent to primary pond, and effluent from primary pond, secondary pond, and three wetland cells planted with cattails were analyzed for about one year from August 2000 to August 2001. The removal rates at primary pond for SS, $BOD_5$, T-N and T-P were 29%, 30%, 15%, and 36%, respectively. The abatement rates at secondary pond for SS, $BOD_5$, T-N and T-P were 38%, 40%, 30%, and 47%, respectively. The reduction rates measured at three cattail-planted wetland cells for SS, $BOD_5$, T-N and T-P were 54%, 57%, 60%, and 68%, respectively. Considering early stage of the pond-wetland system and inclusion of winter during the research period, its treatment efficiency was rather good. Cattails had not yet grown to dense stands due to initial establishment period, which resulted in slightly lower treatment efficiencies of wetland cells for these pollutants, compared with those of ponds.

• Structural Engineering and Mechanics
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• 제23권4호
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• pp.409-430
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• 2006

The aim of this study is to investigate the reliability of strong motion records processed by causal and acausal Butterworth filters in comparison to the results obtained from a synthetic accelerogram. For this purpose, the fault parallel component of the Bolu record of the Duzce earthquake is modeled with a sum of exponentially damped sinusoidal components. Noise-free velocities and displacements are then obtained by analytically integrating the synthetic acceleration model. The analytical velocity and displacement signals are used as a standard with which to judge the validity of the signals obtained by filtering with causal and acausal filters and numerically integrating the acceleration model. The results show that the acausal filters are clearly preferable to the causal filters due to the fact that the response spectra obtained from the acausal filters match the spectra obtained from the simulated accelerogram better than that obtained by causal filters. The response spectra are independent from the order of the filters and from the method of integration (whether analytical integration after a spline fit to the synthetic accelerogram or the trapezoidal rule). The response spectra are sensitive to the chosen corner frequency of both the causal and the acausal filters and also to the inclusion of the pads. Accurate prediction of the static residual displacement (SRD) is very important for structures traversing faults in the near-fault regions. The greatest adverse effect of the high pass filters is their removal of the SRD. However, the noise-free displacements obtained by double integrating the synthetic accelerogram analytically preserve the SRD. It is thus apparent that conventional high pass filters should not be used for processing near-fault strong-motion records although they can be reliably used for far-fault records if applied acausally. The ground motion parameters such as ARIAS intensity, HUSID plots, Housner spectral intensity and the duration of strong-motion are found to be insensitive to the causality of filters.

• 통상정보연구
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• 제9권1호
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• pp.381-399
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• 2007

UCP 600 will now come into effect on 1 July 2007, giving practitioners more than six months to prepare for the change. The vote on the UCP was also a favourable vote on eUCP Version 1.1 which was amended to bring it into conformity with the new rules. ICC Banking commission unanimeusly approved the revised UCP 600 on 26 October 2006 in paris convention. The most important revision of UCP600 have altered the technical and difficult to understand wording of UCP500 into plain simple precise and concise language, The singuler achievement of UCP600 is its elimination of phrase like "reasonable care" "reasonable time" and "an it's face" from the rule. The introduction of separate articles 2 and 3 on "Definitions" and "Interpretation" which contain the concept of "honour" along with the inclusion of certain ISBP wording in UCP, should bring about far greater clarity and precision than in many of the contentions articles in UCP500. The definition of negotiation should help lay to rest the controversies surrounding the terms of negotiation. The removal of reasonable time and the replacement by five banking days should speed the process and make L/Cs more attractive in the market, nevertheless UCP600 have many problems in appling it in practical field. For example the definition of credit, negotiation and purchase it's accepted or undertaken payment draft by accepting bank or deferred payment bank, the second advising bark's position etc. so, I will introduce in this thesis the important revised articles of UCP600 and investigate the problems in applying it in practicle field with reference to the specialist's opinion of the practical field and ICC opinions of drafting Group.

• 상하수도학회지
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• 제27권6호
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• pp.771-778
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• 2013

Gas hydrate (GH) process is a new desalination technology, where GH is a non- stoichiometric crystalline inclusion compounds formed by water and a number of gas molecules. Seawater GH is produced in a low temperature and a high pressure condition and they are separated from the concentrated seawater. The drawback of the GH process so far is that salt contents contained in its product does not meet the fresh water quality standard. This means that the GH process is not a standalone process for seawater desalination and it needs the help of other desalting process like reverse osmosis (RO). The objective of this study is to investigate the effect of GH process on energy saving for RO process in seawater desalination. The GH product water quality data, which were obtained from a literature, were used as input data for RO process simulation. The simulation results show that the energy saving effect by the GH process is in a range of 68 % to 81 %, which increases as the salt removal efficiency of the GH process increases. Boron (B) and total dissolved solids (TDS) concentrations of the final product of the hybrid process of GH and RO were also investigated through the RO process simulation to find relavant salt rejection efficiency of the GH process. In conclusion, the salt rejection efficiency of the GH process should exceed at least 78% in order to meet the product water quality standards and to increase the energy saving effect.

• Archives of Plastic Surgery
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• 제36권2호
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• pp.153-160
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• 2009

Purpose: The heterodigital or homodigital artery island flap is a popular method of reconstruction for finger defects. Sometimes, digital artery island flap has some disadvantages such as postoperative flap edema, congestion, and partial necrosis of the flap margin. However, we could decrease these disadvantages by means of venous superdrainage. The aim of this study is to report usefulness and postoperative results of venous supercharging digital artery island flaps for finger reconstruction. Methods: From March of 2005 to March of 2008, a total of eight patients with soft tissue defects of the finger underwent venous supercharging digital island flap transfer. Briefly, the flap is harvested along with dorsal vein that is then anastomosed to a recipient vein in an end - to - end fashion, after flap transfer and insetting. Using this technique, eight patients were operated on, ranging in age 23 to 52 years. Results: All the flaps survived with a success rate of 100 percent, thus fully satisfying the reconstructive requirements. No postoperative flap congestion was recognized, obviating the need to take any measures for venous engorgement, such as suture removal. Among 8 cases, it was possible to make an long - term and follow - up observation more than 6 months. In these cases, the fact that light touches and temperature sensations can be detected in all the flaps. Cold intolerance and hyperesthesia were not seen in our series. Conclusion: Providing good harmony with conventional methods and microsurgery, inclusion of a vein with the heterodigital and homodigital artery island flap allows a more reliable and safer reconstructive choice for finger defects. The venous supercharged island flap is a reliable flap with a consistent arterial structure, and with its augmented venous drainage, it is more reliable, providing single - stage reconstruction of adjacent finger defects, including the fingertip.

• 펄프종이기술
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• 제35권2호
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• pp.52-57
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• 2003

The charcoal is known to have gas adsorption capability and electrical properties. Some practical applications of carbon materials for the purpose of limited electrical conduction were made in these days. In this paper, we applied the several different kinds of charcoal to the papers in three different ways to investigate if charcoal application method affects its electrical conduction capability. Wet end addition, making multiply, and coating method were tested. The area electrical resistivity of charcoal containing paper was measured. The strength properties of charcoal containing paper were compared to those of the control, which had no charcoal in it. Experimental results showed that manufacturing conditions of the charcoal itself changed its electrical and strength properties of charcoal containing paper. The electrical properties of charcoal containing paper can be used for the removal of electrostatic problem in packaging system. The strength property of the charcoal containing paper should be kept, at least, over the minimum requirement for the packaging system. By using coating method on paper or making multiply, strength loss of paper by inclusion of charcoal could be overcome.

• 콘크리트학회논문집
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• 제13권3호
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• pp.294-300
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• 2001

본 연구는 화력발전소에서 산업부산물로 생산되어지는 bottom ash가 저강도 고유동 충전재(CLSM)의 특성에 미치는 영향을 알아보았다. 저강도 고유동 충전재 재료는 ACI 229소위원회에서 재령 28일 압축강도가 83 kgf/$\textrm{cm}^2$ 보다 낮은 재료로 정의되어져 있으며 이러한 저강도 고유동 충전재에 잔골재를 대신하여 bottom ash가 사용되어 질 수 있는가를 연구하였다. 플로우가 200~300mm이 되도록 시멘트, 플라이애쉬, bottom as, 모래를 혼합하였으며 굴착가능성별로 손도구로 굴착이 가능한 강도 7 kgf/$\textrm{cm}^2$이하, 기계장비를 이용하여 굴착할 수 있는 강도 20 kgf/$\textrm{cm}^2$이하, 굴착이 어려운 강도 83 kgf/$\textrm{cm}^2$이하로 나누어 실험을 실시하였다. 플라이애쉬에 대하여 bottom ash를 25, 50, 75, 100%수준으로 시험하였다. 실험결과 목표로 하는 플로우를 얻기 위해서는 bottom ash의 첨가수준이 증가할수록 단위수량이 증가하였으며 용적 배합이므로 잔골재 양은 감소하는 결과를 나타내었다. Botom ash는 저강도 고유등 충전재의 재료로 사용가능함을 보여주었다.

• Restorative Dentistry and Endodontics
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• 제45권3호
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• pp.38.1-38.10
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• 2020

Objectives: This study aimed to evaluate vital pulp tissue removal from different endodontic instrumentation systems from root canal apical third in vivo. Materials and Methods: Thirty mandibular molars were selected and randomly divided into 2 test groups and one control group. Inclusion criteria were a positive response to cold sensibility test, curvature angle between 10 and 20 degrees, and curvature radius lower than 10 mm. Root canals prepared with Hero 642 system (size 45/0.02) (n = 10) and Reciproc R40 (size 40/0.06) (n = 10) and control (n = 10) without instrumentation. Canals were irrigated only with saline solution during root canal preparation. The apical third was evaluated considering the touched/untouched perimeter and area to evaluate the efficacy of root canal wall debridement. Statistical analysis used t-test for comparisons. Results: Untouched root canal at cross-section perimeter, the Hero 642 system showed 41.44% ± 5.62% and Reciproc R40 58.67% ± 12.39% without contact with instruments. Regarding the untouched area, Hero 642 system showed 22.78% ± 6.42% and Reciproc R40 34.35% ± 8.52%. Neither instrument achieved complete cross-sectional root canal debridement. Hero 642 system rotary taper 0.02 instruments achieved significant greater wall contact perimeter and area compared to reciprocate the Reciproc R40 taper 0.06 instrument. Conclusions: Hero 642 achieved higher wall contact perimeter and area but, regardless of instrument size and taper, vital pulp during in vivo instrumentation is not entirely removed.

• 중환자간호학회지
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• 제15권3호
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• pp.75-87
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• 2022

Purpose : This retrospective investigation study aimed to determine the predictive validity of superficial surgical site infection assessment tools by measuring the risk score at the surgical site. Methods : This study included patients hospitalized to the general surgery department of a Hospital from January 2021 to December 31, 2021. The inclusion criteria were age ≥19 years, general abdominal surgery under general anesthesia, and hospital stay longer than 2 days. Patients who had undergone transplantation were excluded. Results : Tool validity results showed that tools including surgical time and operative procedure were more accurate than previously developed tools, with a sensitivity of 71.1%, specificity of 71.4%, positive prediction of 12.3%, negative prediction of 97.8%, and area under the curve of 0.743 (95% confidence interval, 0.678~0.745). The tool's cut-off score was 15, and the risks of infection was increased by 6.14 times at or above this cut-off point. Preoperative hair removal period, surgical wound classification, surgery time, body temperature on the second day after surgery, drainage tube type, and suture type affected the risk of infection at the surgical site. Conclusion : The incidence of healthcare-associated infections has been declining in the past decade; however, surgical site infections still account for a considerable proportion. Therefore, early identification of high-risk groups for surgical site infection is crucial for reducing the incidence of surgical site infection using appropriate management.