• Title/Summary/Keyword: Incidence distribution

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Risk of the Gastric Cancer Associated with the Interleukin $1\beta$ Gene Polymorphism and Helicobacter pylori (Helicobacter pylori 감염과 Interleukin $1\beta$ 유전자의 다형성에 따른 위암 발생 위험도)

  • Park, Sang-Hyub;Song-Kyo-Young;Kim, Jin-Jo;Jin-Hyung-Min;Kim, Wook;Park, Cho-Hyun;Park, Seung-Man;Lim-Keun-Woo;Park, Woo-Bae;Kim, Seung-Nam;Jeon, Hae-Myung
    • Journal of Gastric Cancer
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    • v.4 no.3
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    • pp.149-155
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    • 2004
  • Purpose: According to the recent studies, it is shown that the polymorphism of Interleukin $1\beta$ gene is associated with the incidence of gastric cancer caused by the Helicobacter pylori infection. Interleukin $1\beta$ is a cytokine markedly inhibiting gastric acid secretion. Interleukin $1\beta$ production associated with Helicobacter pylori gastric infection may exacerbate mucosal damage including chronic gastritis and atrophic gastritis, may induce eventual neoplasia. Among these Interleukin $1\beta$ gene polymorphisms, polymorphisms at -31 portion and -511 portion may associated with these processes, eventually increase the risk of gastric cancer. We investigated the risk of gastric cancer according to the Helicobacter pylori infection and genetic polymorphism of Interleukin $1\beta$ in gastric cancer patients. Materials and Methods: 176 individuals with gastric cancer and 40 healthy controls were analyzed. Each group was divided into two groups whether they infected with Helicobacter pylori or not. DNA was extracted from the peripheral blood in all groups. The PCR-RFLP method was used for investigating the distribution of genotype of C/C, C/T, T/T at -31 portion and -511 portion. Results: T/T genotype at -511 portion was $19.3\%$ in gastric cancer cases and $10\%$ in controls, which was statistically significant. (P=0.0432) The risk of gastric cancer was increased 4.86 ($1.26\∼18.77$) in group which had T/T genotype. In gastric cancer cases, C/C genotype at 31 portion was $27.6\%$ in group with Helicobacter pylori infection and $12.8\%$ in group without infection, which was statistically significant. (P=0.0047) The risk of gastric cancer was increased 4.82 ($1.81\~12.81$) in group which had C/C genotype. Conclusion: T genotype at -511 portion among the Interleukin $1\beta$ genetic polymorphisms may be the risk factor of gastric cancer. And, with Helicobacter pylori infection, C genotype at -31 portion may be the risk factor of gastric cancer.

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Analysis of Backscattering Coefficients of Corn Fields Using the First-Order Vector Radiative Transfer Technique (1차 Vector Radiative Transfer 기법을 이용한 옥수수 생육에 따른 후방산란 특성 분석)

  • Kweon, Soon-Koo;Hwang, Ji-Hwan;Park, Sin-Myeong;Hong, Sungwook;Oh, Yisok
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.25 no.4
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    • pp.476-482
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    • 2014
  • In this study, we analyzed the effect of corn growth on the radar backscattering coefficient. At first, we measured the backscattering coefficients of various corn fields using a polarimetric scatterometer system. The backscattering coefficients of the corn fields were also computed using the 1st-order VRT(Vector Radiative Transfer) model with field-measured input parameters. Then, we analyzed the experimental and numerical backscattering coefficients of corn fields. As a result, we found that the backscatter from an underlying soil layer is dominant for early growing stage. On the other hand, for vegetative stage with a higher LAI(Leaf-Area-Index), the backscatter from vegetation canopy becomes dominant, and its backscattering coefficients increase as incidence angle increases because of the effect of leaf angle distribution. It was also found that the estimated backscattering coefficients agree quite well with the field-measured radar backscattering coefficients with an RMSE(Root Mean Square Error) of 1.32 dB for VV-polarization and 0.99 dB for HH-polarization. Finally, we compared the backscattering characteristics of vegetation and soil layers with various LAI values.

Aerial Distribution of Bacterial Groups of Xanthomonas oryzae (Uyeda et Ishiyama) Dowson in Korea (벼 흰빛잎마름병균의 균군의 분포에 관한 연구)

  • Choi Yong Chull;Lee Soon Gu;Chung Bong Jo;Cho Yong Sup
    • Korean journal of applied entomology
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    • v.18 no.1 s.38
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    • pp.23-27
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    • 1979
  • Studies on bacterial groups of X. oryzae in Korea has been continued annually since 1975. The present report maintained the result of recent Studies covering on 224 isolates collected front 191 portions of all over the country during the period from 1977 to 1978. The four bacterial groups, I, II, III and V, were found with the ratio of 79, 16, 3 and 3 per-cent, respectively. Variable bacterial groups were found in Chung- nam province while in Jeon- nam province the group II was more pre4valent than group I. Variety-group 'Kimmaze' maintained much more of heterogeneous bacterial groups, and it was significant, especially, on cultivar Milyang $\#23$. Variety-group 'Kogyoku' maintained group II, only while it was possible to isolate group I, II, and III from variety group 'Rantai-emas.' Isolates from Kresek symptom, mostly on Milyang $\#23$, belonged to group I and group II, and their occurring incidence were 20 and 8 out of 28 isolates, respectively. Variability of bacterial group was differed with the location of fields. There were homogeneous and heterogeneous groups, respectively, regardless of host varieties in a given locations.

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Clinical Characteristics and Antibiotic Resistance of Urinary Tract Infections in Children: Escherichia. coli Versus Non-E. coli (소아 요로감염의 원인균주별 임상양상과 항생제 내성률 : 대장균과 비대장균의 비교)

  • Bae, E-Young;Lee, Soo-Young;Jeong, Dae-Chul;Kang, Jin Han
    • Pediatric Infection and Vaccine
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    • v.17 no.2
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    • pp.67-73
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    • 2010
  • Purpose : We aimed to compare the clinical features and antibiotic resistance of urinary tract infection (UTI) caused by pathogens other than E. coli (non-E. coli) with UTI caused by E. coli in children. Methods : We enrolled patients with culture-proven UTI, who were admitted to the study hospital from September 2008 to August 2009. We investigated clinical data of patients with UTI and antibiotic resistance of isolated strains. For comparison, patients were divided according by results of the urine culture into E. coli and non-E. coli UTI groups. Results : A total of 84 patients participated in this study. Twenty one cases (25.0%) were caused by non-E. coli pathogens. Frequency of non-E. coli UTI differed according to age and sex: 'male <6 months', 10.5%; 'male ${\geq}$6 months', 50.0%; 'female <6 months', 43.7%; and 'female ${\geq}$6 months', 25.0% (P=0.014). More patients who received previous antibiotic treatment (P=0.017), but fewer patients who showed hematuria (P=0.014) were included in the non-E. coli UTI group than in the E. coli UTI group. Comparison of antibiotic resistance showed that the non-E. coli UTI group possessed more strains that were resistant to cefazolin, cefotaxime, imipenem, trimethoprim/sulfamethoxazole (TMP/SMZ) and tetracycline than the E. coli UTI group (P<0.05). Conclusion : Increased incidence, different distribution by age and sex, and high antibiotic resistance of non-E. coli UTI should be considered in selection of empirical antibiotics for treatment of UTI in children.

Current status of vivax malaria among civilians in Korea (한국에서의 민간인 삼일열말라리아 발생현황)

  • Jong-Soo LEE;Weon-Gyu KHO;Hyeong-Woo LEE;Min SEO;Won-Ja LEE
    • Parasites, Hosts and Diseases
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    • v.36 no.4
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    • pp.241-248
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    • 1998
  • A result of national malaria surveillance in Korean civilians was described. Since a case of indigenous vivax malaria was detected in 1993, a total of 2,198 cases was confirmed by blood smear up to 1997. Of them, 1,548 cases were soldiers serving in the demilitarized zone (DMZ), while 650 cases were civilians. Number of civilian cases was 3 in 1994, 19 in 1995, 71 in 1996, and 557 in 1997. Of them, 239 were ex-soldiers who discharged after military service in the prevalent areas such as Paju, Yonchon, Kimpo, Kangwha, Tongduchon in Kyonggi-do and Chorwon in Kangwon-do while 308 patients were civilian residents in the prevalent areas. Seventy-two patients, living nationwide, had a history of visiting the prevalent areas during transmission season. Only 32 civilian patients denied any relation with the prevalent areas. As a whole, a half of the civilian cases was diagnosed when living in non-prevalent areas. Male patients in their twenties was the highest in number. Annual parasite index is steadily elevated in residents living in the prevalent areas. Monthly incidence showed an unimodal distribution, forming a peak in August. Ex-soldiers exhibited a delayed incubation ranging from 153 to 452 days ($279{\pm}41$ days). The time required for diagnosis was shortened from 23.6 days in 1995 to 13.7 days in 1997. Although the current epidemic of vivax malaria started as a border malaria, it seems highly probable that vivax malaria is established in the local areas and responsible for at least a part of transmission.

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Research Review on Turfgrass Disease in Korea (한국의 잔디병해 연구사)

  • Shim, Gyu Yul;Lee, Jung Han
    • Weed & Turfgrass Science
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    • v.7 no.2
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    • pp.87-97
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    • 2018
  • Turfgrass provides various beneficial effects to our societies such as recreation, aesthetic components, and other public service. Diseases in turfgrass is the major issue, which cause quality problems in golf courses, playgrounds, parks and cultivation areas, and tremendous cost is required to prevent the diseases. Research activity and investigation for turfgrass disease remain to be further attributed when compared to other crops in Korea. In this study, we present previously reported turfgrass diseases researches, especially caused by fungal pathogens, and review the history of turfgrass research activity in Korea to contribute future turfgrass research direction. Research papers were searched and analyzed using Korea Educational and Research Information Service (www.riss.kr). More than eighty papers presented turfgrass diseases and among the papers, 50% were published in Korean Journal of Turfgrass. Half of the papers reported turfgrass diseases control. Research articles about large patch disease were the majority (36%), followed dollar spot (18%), Pythium blight (10%) and Typhular blight (8%). Number of the first disease reports in Korea were total fifteen. Total 542 fungicides have been registered in Korea to prevent turfgrass diseases and most of the fungicides were for brown patch, rust, yellow patch, dollar spot, snow mold, summer patch, anthracnose, Pythium blight, powdery mildew and algae. And we will also need to conduct ecological studies on turf diseases and to develop control methods with improved efficacy and environmentally-friend sound. Researches on epidemiology of turfgrass diseases which deals with the incidence, distribution, and interactions with other factors will be also greatly favored for precise control prescription, timing of control and use of less pesticides.

Characterization of Radiation Field in the Steam Generator Water Chambers and Effective Doses to the Workers (증기발생기 수실의 방사선장 특성 및 작업자 유효선량의 평가)

  • Lee, Choon-Sik;Lee, Jai-Ki
    • Journal of Radiation Protection and Research
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    • v.24 no.4
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    • pp.215-223
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    • 1999
  • Characteristics of radiation field in the steam generator(S/G) water chamber of a PWR were investigated and the anticipated effective dose rates to the worker in the S/G chamber were evaluated by Monte Carlo simulation. The results of crud analysis in the S/G of the Kori nuclear power plant unit 1 were adopted for the source term. The MCNP4A code was used with the MIRD type anthropomorphic sex-specific mathematical phantoms for the calculation of effective doses. The radiation field intensity is dominated by downward rays, from the U-tube region, having approximate cosine distribution with respect to the polar angle. The effective dose rates to adults of nominal body size and of small body size(The phantom for a 15 year-old person was applied for this purpose) appeared to be 36.22 and 37.06 $mSvh^{-1}$) respectively, which implies that the body size effect is negligible. Meanwhile, the equivalent dose rates at three representative positions corresponding to head, chest and lower abdomen of the phantom, calculated using the estimated exposure rates, the energy spectrum and the conversion coefficients given in ICRU47, were 118, 71 and 57 $mSvh^{-1}$, respectively. This implies that the deep dose equivalent or the effective dose obtained from the personal dosimeter reading would be the over-estimate the effective dose by about two times. This justifies, with possible under- or over- response of the dosimeters to radiation of slant incidence, necessity of very careful planning and interpretation for the dosimetry of workers exposed to a non-regular radiation field of high intensity.

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Gynecologic Application of the Pelviscopic Surgery (골반경수술의 부인과적 응용)

  • Koh, Seok-Bong;Lee, Jae-Yeoul;Lee, Young-Gi;Park, Yoon-Kee;Lee, Doo-Jin;Lee, Tae-Hyung;Lee, Sung-Ho
    • Journal of Yeungnam Medical Science
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    • v.11 no.1
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    • pp.127-134
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    • 1994
  • The aim of this study was to identify the usefulness of pelviscopy in treatment besides its diagnostic value. The advantages of pelviscopic surgery are low cost, rapid recovery, good cosmetic effect, low incidence of complication and postoperative adhesion. So most of the pelvic exploration in gynecologic patients are replaced by the pelviscopic surgery these days. Pelviscopic surgery was performed on 136 patients at the Department of Obstetrics and Gynecology, College of Medicine, Yeungnam University from May 1991 to July 1993. The results obtained were as follows : The age distribution of the patients was from 19 to 55 with age of 31.2 years, and the mean parity was 0.96, the most common indication of pelviscopic surgery was tubal pregnancy(66.9%), the second most common indications was ovarian cyst(10.3%) and the other indications were endometriosis, corpus luteum cyst rupture, parovarian cyst, foreign body, tubal ligation, hydrosalpinx, uterine myoma and diagnostic procedure. The main types of surgery were salpingectomy in 58.8% and salpingoophorectomy in 16.3%. The mean duration of hospitalization was 2.1 days without specific complications. According to these results, it was postulated that the pelviscopic surgery was a useful operative tool in gynecologic treatment and its application could be extended to many other areas of gynecology with safety by the development of surgical techniques and instruments.

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Cancer Notification at a Referral Hospital of Kermanshah, Western Iran (2006-2009)

  • Rahimi, Zohreh;Kasraei, Razieh;Najafi, Farid;Tanhapoor, Maryam;Abdi, Hamed;Rahimi, Ziba;Vaisi-Raygani, Asad;Aznab, Mozafar;Moradi, Mahmoudreza
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.133-137
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    • 2015
  • Background: Cancer is a major public health problem and the leading cause of mortality in both males and females in developed and developing countries. The incidence of cancer is gender dependent. Among Iranians, it is the third cause of death. Materials and Methods: The information recorded in the files of all patients (7,695 individuals) pathologically diagnosed with cancer in Imam Reza referral hospital of Kermanshah University of Medical Sciences during the four year period of 2006-2009 were reviewed and analyzed using SPSS statistical software package version 16.0. Results: Around 61.6% of reported cancer cases were males and 38.4% were females. The most prevalent reported malignant tumors occurred at the age group of 70-79 years in males and in females these tumors were presented in the ages of 60-69 years. The most prevalent cancers among studied patients were gastrointestinal (GI) cancers with a frequency of 22.9% [gastric 10.7%, colorectal 6.9%, and esophageal 6%]. The second, third and forth prevalent cancers were blood at 16.4%, lung 13.5% and bladder 12.8%, respectively. In males the cancers of GI (25.6%) were the most prevalent followed in order of frequency by bladder (18%), blood (17.6%), lung (17.4%) and prostate (6.8%). In females the most frequent recorded cancer was breast (24.1%) followed in order of frequency by GI (20.5%), blood (14.4%), lung (7.3%), uterus (6.2%) and ovary (5.1%). Breast cancer was the most prevalent cancer (27%) in the age group of 40-49 years. Conclusions: The present study provides frequency data for various types of cancers in both males and females from a referral hospital of Kermanshah that are comparable with some reports from other areas of the country.

Retrospective Study of Cysts in the Oral and Maxillofacial Regions: Statistical and Clinical Analysis

  • Lee, Hyun-Kyung;Ryu, Kyung-Sun;Kim, Moo-Gun;Park, Kwang-Won;Kim, Ryun-Ga;Roh, Sang-Hwa;Jung, Tae-Young;Park, Sang-Jun
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.36 no.1
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    • pp.1-6
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    • 2014
  • Purpose: This study was designed for identification of the main clinicopathological features of cysts in the oral and maxillofacial regions. Methods: A retrospective observational study was conducted on 164 patients who had been diagnosed with cyst of the jaw, from the database of 168 histopathological diagnoses at the Department of Oral and Maxillofacial Surgery of Busan Paik Hospital at Inje University, from January 2009 to December 2011. The subjects were treated and the following variables were recorded: gender, age, clinical signs and symptoms, histopathological distribution, treatment methods, and complications. A descriptive analysis of the study variables was performed using a chi-square test. Results: Among the 164 patients, there were more male than female patients (male-female ratio: 1.7:1). The most predominant ages were the 20s and 40s. Among the classes of pathological cysts, radicular cysts and dentigerous cysts were the most common, with incidences of 56.0% and 35.1%. Thirty-six percent of the patients had no symptoms; and of those who had symptoms, the main signs and symptoms were swelling (24.4%) and pain (17.1%). The most frequent management method was the combination operation, such as enucleation with or without extraction and apicoectomy of the causative teeth. Of the 164 patients, 13 had complications; and one patient who had been treated with enucleation with apicoectomy had a recurrent cyst. Conclusion: Using a chi-square test, no significant differences in prevalence were observed in relation to gender according to age. Comparative analysis of radicular and dentigerous cysts showed a significant difference in their prevalence according to their anatomical location, however, no significant differences in were observed in their incidence rates according to age.