• Title/Summary/Keyword: IncF

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Linkage Disequilibrium (LD) Mapping and Tagging SNP Selection of C-Fos Induced Growth Factor (Figf) Gene in Korean Population

  • Kim, Sook;Yoo, Yeon-Kyung;Jang, Hye-Yoon;Shin, Eun-Soon;Cho, Eun-Young;Kim, Eu-Gene;NamKung, Jung-Hyun;Yang, Jun-Mo;Lee, Jong-Eun
    • Molecular & Cellular Toxicology
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    • v.2 no.1
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    • pp.7-10
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    • 2006
  • We performed comprehensive SNP validation and linkage disequilibrium (LD) analysis of the c-fos induced growth factor (Figf) gene in Korean population. Out of 32 SNPs, only 9 SNPs were polymorphic in Korean population. Validated SNPs formed a single extended haplotype block with strong LD through the entire length of the gene. Tagging SNP analysis picked only 2 SNPs to represent most of the genetic variation information of the Figf gene. Our results demonstrate the utility of LD block and tagging SNP analysis for an efficient way of performing a candidate gene based association study.

Enhancement of Skin Antioxidant and Anti-Inflammatory Potentials of Agastache rugosa Leaf Extract by Probiotic Bacterial Fermentation in Human Epidermal Keratinocytes (프로바이오틱 유산균 발효에 의한 배초향 잎 추출물의 피부 항산화 및 항염증 활성 증대)

  • Lim, Hye-Won;Lee, Yoonjin;Huang, Yu-Hua;Yoon, Ji-Young;Lee, Su Hee;Kim, Kyunghoon;Lim, Chang-Jin
    • Microbiology and Biotechnology Letters
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    • v.45 no.1
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    • pp.35-42
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    • 2017
  • This study aimed to investigate the effects of probiotic fermentation by comparing the skin antioxidant and anti-inflammatory properties of non-fermented (ARE) and fermented (ARE-F) hot water extracts of Agastache rugosa leaves. ARE-F was obtained via ARE fermentation using Lactobacillus rhamnosus HK-9. In vitro, anti-inflammatory properties were evaluated by analyzing the levels of nitric oxide (NO), reactive oxygen species (ROS), and inducible nitric oxide synthase (iNOS) in lipopolysaccharide (LPS)-stimulated HaCaT keratinocytes. In vitro antiradical activity was measured using 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay. Attenuation of LPS-stimulated NO (p < 0.01), ROS (p < 0.001) and iNOS (p < 0.05) levels by ARE-F was significantly stronger than that by ARE in HaCaT keratinocytes. However, no differences were observed between the DPPH radical scavenging activities of ARE and ARE-F. ARE-F possesses enhanced skin antioxidant and anti-inflammatory properties, suggesting that probiotic bacterial fermentation can be considered an effective tool for augmenting some pharmacological properties of A. rugosa leaves. In brief, the skin antioxidant and anti-inflammatory potentials of A. rugosa leaf extract are augmented by the fermentation with L. rhamnosus HK-9, a probiotic bacterium.

Motor drive control development: a new approach to learning and design

  • Porobic, Vlado;Ivanovic, Zoran;Adzic, Evgenije;Vekic, Marko;Celanovic, Nikola;Oh, Hyounglok
    • Proceedings of the KIPE Conference
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    • 2013.11a
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    • pp.37-38
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    • 2013
  • This paper presents an intuitive and powerful way to study and design motor drive control. The control of induction motors, as most widely used machines, is discussed. Thanks to ultra low latency and high fidelity Hardware-in-the-Loop systems, different aspects of up-to-date drive regulation are examined. A power stage, comprised of a grid voltage source, a rectifier, a VSC inverter and an induction motor, is emulated on the HIL platform in real time. A digital signal controller is plugged into the interface board and connected to the HIL emulation platform, without any hardware modifications. For motor control and power electronics applications, a dedicated Texas Instruments TMS320F2808 DSP is chosen. The same controller can drive an emulation platform and a real device with no modifications. Current and speed control loop test results are presented and discussed.

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Properties of fluorine-doped $SnO_2$ films perpared by the in-line APCVD system (In-line APCVD에 의해 제작된 $SnO_2(:F)$ film의 특성)

  • Sei Woong Yoo;Byung Seok Yu;Jeong Hoon Lee
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.4 no.2
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    • pp.157-168
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    • 1994
  • The surface morphology, electrical properties, and optical properties of textured $SnO_2(:F)$ films according to deposition parameters such as HF and $H_2O$ content was studies. The electron concentration, resistivity, and mobility was $3{\Times}10^{20}/cm^3$, $7{\Times}10^4~9{\Times}10^4{Omega}cm$ and $18~25cm^2/V.sec$, respectively, when HF bubbling rate over 0.9 slm. The surface morphology was sharp edged pyramid shape without bubbling $H_2O$ but changed to round edged hemispherical shape when $H_2O$ was added.

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