• Geotechnical Engineering
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• v.14 no.5
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• pp.143-162
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• 1998

In the present study, a procedure to predict the depth from the ground surface to the center of bulging failure zone in each of the square granular group piles under a rigid mat foundation is proposed. This analytical procedure is established on the basis of the conical modeling of bulging failure shape and the replacement ratio of soft foundation soils. considering the effect of a share of procedure to estimate the ultimate cylindrical pressure in the area reinforced with granular piles and the ultimate bearing capacity of each of granular piles in group. This analytical procedure is also established on the basis of the pre-determined depth to the zone of bulging failure and an iterative solution technique. Finally the analytical procedures proposed in this study are verified by analyzing the results of 3D finite element analyses, and the predictions of ultimate bearing capacity of granular piles are compared with the results obtained from the tests, empirical equation and 3D finite element analyses.

• Korean Journal of Acupuncture
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• v.20 no.2
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• pp.55-66
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• 2003

Objectives : The aim of this experiment is to investigate the effects of moxibustion on SP6, Sp9 and BL28 in uranyl acetate-induced acute renal failure in rats. Methods : To induce experimental acute renal failure, uranyl acetate was intraperitoneally injected to rats by 5mg/kg. 3 days later moxibustion treatment was done at SP6, Sp9 and BL28 bilaterally of the rats. And then 4 days later, we measured rats' body weight, kidney weight, serum BUN, creatinine and serum electrolytic levels(Na, K and Cl). Results : In the SP6 group, serum BUN were significantly decreased (p<0.01). In the BL28 group, serum Na level were significantly decreased (p<0.05). In the $SP6{\cdot}SP9$ group, serum creatinine level were significantly increased but serum Na level, serum Cl level were significantly decreased(p<0.05). In the $SP6{\cdot}BL28$ group, hypertrophy index of kidney and serum creatinine level were significantly decreased(p<0.01) and serum BUN were marginally significantly decreased (0.1

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5699-5703
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• 2013

Objective: To investigate the clinical effects of whole brain radiotherapy concomitant with targeted therapy for brain metastasis in non-small cell lung cancer (NSCLC) patients with chemotherapy failure. Materials and Methods: Of the 157 NSCLC patients with chemotherapy failure followed by brain metastasis admitted in our hospital from January 2009 to August 2012, the combination group (65 cases) were treated with EGFR-TKI combined with whole brain radiotherapy while the radiotherapy group (92 cases) were given whole brain radiotherapy only. Short-term effects were evaluated based on the increased MRI in brain 1 month after whole brain radiotherapy. Intracranial hypertension responses, hematological toxicity reactions and clinical effects of both groups were observed. Results: There were more adverse reactions in the combination group than in radiotherapy group, but no significant differences were observed between the two groups in response rate (RR) and disease control rate (DCR) (P>0.05). Medium progression free survival (PFS), medium overall survival (OS) and 1-year survival rate in combination group were 6.0 months, 10.6 months and 42.3%, while in the radiotherapy group they were 3.4 months, 7.7 months and 28.0%, respectively, which indicated that there were significant differences in PFS and OS between the two groups (P<0.05). Additionally, RPA grading of each factor in the combination group was a risk factor closely related with survival, with medium PFS in EGFR and KRAS mutation patients being 8.2 months and 11.2 months, and OS being 3.6 months and 6.3 months, respectively. Conclusions: Whole brain radiotherapy concomitant with target therapy is favorable for adverse reaction tolerance and clinical effects, being superior in treating brain metastasis in NSCLC patients with chemotherapy failure and thus deserves to be widely applied in the clinic.

• Asian Journal of Innovation and Policy
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• v.3 no.1
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• pp.25-49
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• 2014

We wanted to show the different group dynamics of factors for success and failure cases for technology commercialization in small technology-based firms. Existing studies are based on product level, project level, division level or firm level. We deal with technology level, and at small-technology-based firms. This is a longitudinal case study based on 8 cases from Korea. Our study on technology level is a first trial in success and failure studies unlike all existing studies. As a first step, we introduced new categories and factors such as technology attributes and CEO reflecting data, and especially a new concept of launch readiness level. Finally, we adopted correspondence analysis to show the group dynamics. The results are as follows; Technology factors are the most important factors. Second, resource-based factors are more critical in failure cases than success cases and technology factors are more critical to success.

• Journal of the Korea Safety Management & Science
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• v.6 no.1
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• pp.61-70
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• 2004

In this paper, a group replacement policy based on a failure count is analysed. For a group of identical repairable units, a maintenance policy is performed with two phase considerations: a repair interval phase and a waiting interval phase. Each unit undergoes minimal repair at failure during the repair interval. Beyond the interval, no repair is made until a number of failures. The expected cost rate expressions under the policy is derived. A method to obtain the optimal values of decision variables are explored. Numerical examples are given to demonstrate the results.

• Proceedings of the Korean Geotechical Society Conference
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• 2009.09a
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• pp.660-670
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• 2009

Neighboring construction becomes mainstream of Ground excavation in downtown area. This causes the displacement, deformation, stress condition, etc of the ground surroundings. Therefore Neighboring construction have an effect on Neighboring structure. All these years a lot of Neighboring construction carried out, and the accumulation of technology also get accomplished. But earth retaining structure collapse happens yet. Types of earth retaining structure collapse are 12. 1. Failure of anchor or strut system, 2. Insufficiency of penetration, 3. H-pile Failure on excessive bending moment, 4. Slope sliding failure, 5. Excessive settlement of the back, 6. Deflection of H-pile, 7. Joint failure of coupled H-pile, 8. Rock failure when H-pile penetration is rock mass, 9. Plane arrangement of support systems are mechanically weak, 10. Boiling, 11. Heaving, 12. Over excavation. But field collapses are difficult for classification according to the type, because collapse process are complex with various types. When we consider the 12 collapse field, insufficient recognition of ground condition is 4 case. Thorough construction management prevents from fault construction. For limitations of soil survey, It is difficult to estimate ground condition exactly. Therefore, it should estimate the safety of earth retaining system, plan for necessary reinforcement, according to measurement and observation continuously.

• Korean Journal of Acupuncture
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• v.22 no.4
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• pp.117-127
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• 2005

Objective : This study was undertaken to determine if Plantaginis Semen herbal acupuncture(PSA) has a protective effect on glycerol-induced acute renal failure in rats. Methods : Rats were dehydrated for 24hr and then injected with 4 ml/kg of 50% glycerol in each hindlimb muscle. In experiments for PSA effect, rats were received 0.1 ml of PSA extraction in both sides of corresponding $Sh\grave{e}nsh\bar{u}(BL_{23})$ of human body for 3 days after injection of glycerol. The experimental group were divided into the normal group, the control group, the sample 1,2,3 group. Results : Glycerol injection decreased glomerular filtration rate and increased urine volume, serum creatinine, BUN level and fractional excretion of $Na^+,\;K^+\;and\;Cl^-$. These results show that glycerol injection bring about acute renal failure. PSA significantly increased glomerular filtration rate and significantly decreased serum creatinine, BUN level and fractional excretion of $Na^+,\;and\;Cl^-$ as compared with control group. Conclusion : These results suggest that PSA can be used in prevention and treatment for acute renal failure. However, the precise mechanisms of PSA protection remain to be determined.

• Structural Engineering and Mechanics
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• v.39 no.2
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• pp.207-221
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• 2011

This paper aims to study the behavior of short reinforced concrete columns confined with external glass Fiber Reinforced Polymers (GFRP) sheets under eccentric loads. The experimental part of the study was achieved by testing 9 specimens under eccentric compression. Three eccentricity ratios corresponding to e/t = 0, 0.10, 0.50 in one direction of the column were used. Specimens were divided into three groups. The first group was the control one without confinement. The second group was fully wrapped with GFRP laminates before loading. The third group was wrapped under loading after reaching 75% of failure loads of the control specimens. The third group was investigated in order to represent the practical case of strengthening a loaded column with FRP laminates. All specimens were loaded until failure. The results show that GFRP laminates enhances both failure load and ductility response of eccentrically loaded column. Moreover, the study also illustrates the effect of confinement on the first crack load, lateral deformation, strain in reinforcement and failure pattern. Based on the analysis of the experimental results, a simple model has been proposed to predict the improvement of load carrying capacity under different eccentricity ratios. The predicted equation takes into consideration the eccentricity to cross section depth ratio, the ultimate strength of GFRP, the thickness of wrapping laminate, and the time of wrapping (before loading and under loading). A good correlation was obtained between experimental and analytical results.

• The Journal of the Korea Contents Association
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• v.21 no.3
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• pp.602-608
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• 2021

For the comparison of bond strength between the Co-Cr alloy and ceramic, which are clinically used, test samples made with a traditional casting method as a control group), and Milling and SLM(3d printing group) samples were made as an experimental group. The metal-ceramic bond strength was measured with a universal testing machine. For the measurement, a three-point bending test was conducted. After the bond strength was measured, metal-ceramic interface was observed. According to the test result, casting group had 53.59 MPa, milling group had 45.90 MPa, and 3d printing group had 58.34 MPa. There was no statistical significance. With regard to failure pattern, most of the samples in two groups, showed mixed failure. This study showed a clinically applicable value when measuring the bond strength of alloy-ceramic material with an alloy produced by 3D printing.

• Journal of Dental Anesthesia and Pain Medicine
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• v.15 no.3
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• pp.113-119
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• 2015

Background: The inferior alveolar nerve block (IANB) is the most common anesthetic techniques in dentistry; however, its success rate is low. The purpose of this study was to determine the correlation between IANB failure and mandibular skeletal characteristics Methods: In total, 693 cases of lower third molar extraction (n = 575 patients) were examined in this study. The ratio of the condylar and coronoid distances from the mandibular foramen (condyle-coronoid ratio [CC ratio]) was calculated, and the mandibular skeleton was then classified as normal, retrognathic, or prognathic. The correlation between IANB failure and sex, treatment side, and the CC ratio was assessed. Results: The IANB failure rates for normal, retrognathic, and prognathic mandibles were 7.3%, 14.5%, and 9.5%, respectively, and the failure rate was highest among those with a CC ratio < 0.8 (severe retrognathic mandible). The failure rate was significantly higher in the retrognathic group than in normal group (P = 0.019), and there was no statistically significant difference between the other two groups. Conclusions: IANB failure could be attributable, in part, to the skeletal characteristics of the mandible. In addition, the failure rate was found to be significantly higher in the retrognathic group.