• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.5043-5047
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• 2014

Nowadays increasing effectiveness in cancer therapy and investigation of formation of new strategies that enhance antiproliferative activity against target organs has become a subject of interest. Although the molecular mechanisms of apoptosis can not be fully explained, it is known that cell suicide program existing in their memory genetically is activated by pathophysiological conditions and events such as oxidative stress. Low pressure (hypobaric) conditions that create hypoxia promote apoptosis by inhibiting cell cycling. In this study, determination of the effects of fractional hypobaric applications at different times on HeLa cells at cellular and molecular levels were targeted. Experiments were carried out under hypobaric conditions (35.2 kPa) in a specially designed hypobaric cabin including 2% $O_2$ and 98% N. Application of fractional hypobaric conditions was repeated two times for 3 hours with an interval of 24 hours. At the end of the implementation period cells were allowed to incubate for 24 hours for activation of repair mechanisms. Cell kinetic parameters such as growth rate (MTT) and apoptotic index were used in determination of the effect of hypobaric conditions on HeLa cells. Also in our study expression levels of the Bcl-2 gene family that have regulatory roles in apoptosis were determined by the RT-PCR technique to evaluate molecular mechanisms. The results showed that antiproliferative effect of hypobaric conditions on HeLa cells started three hours from the time of application and increased depending on the period of exposure. While there was a significant decrease in growth rate values, there was a significant increase in apoptotic index values (p<0.01). Also molecular studies showed that hypobaric conditions caused a significant increase in expression level of proapoptotic gene Bax and significant decrease in antiapoptotic Bfl-1. Consequently fractional application of hypobaric conditions on HeLa cell cultures increased both antiproliferative and apoptotic effects and these effects were triggered by the Bax gene.

• Journal of Korea Multimedia Society
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• v.8 no.10
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• pp.1369-1382
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• 2005

Vehicle segmentation, which extracts vehicle areas from road scenes, is one of the fundamental opera tions in lots of application areas including Intelligent Transportation Systems, and so on. We present a vehicle segmentation approach for still images captured from outdoor CCD cameras mounted on the supporting poles. We first divided the input image into a set of two-dimensional grids and then calculate the feature values of the edges for each grid. Through analyzing the feature values statistically, we can find the optimal rectangular grid area of the vehicle. Our preprocessing process calculates the statistics values for the feature values from background images captured under various circumstances. For a car image, we compare its feature values to the statistics values of the background images to finally decide whether the grid belongs to the vehicle area or not. We use dynamic programming technique to find the optimal rectangular gird area from these candidate grids. Based on the statistics analysis and global search techniques, our method is more systematic compared to the previous methods which usually rely on a kind of heuristics. Additionally, the statistics analysis achieves high reliability against noises and errors due to brightness changes, camera tremors, etc. Our prototype implementation performs the vehicle segmentation in average 0.150 second for each of $1280\times960$ car images. It shows $97.03\%$ of strictly successful cases from 270 images with various kinds of noises.

• Journal of Korea Multimedia Society
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• v.10 no.11
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• pp.1496-1506
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• 2007

The environment of web service has changed a great deal due to the progress of internet technology and positive participation of users. The established web service is static and passive, but the recent web service is becoming dynamic and active. Web 2.0 reflects current web service change well. The primary feature of web 2.0 is positive participation of users. Since the size of generated information is becoming larger, it is highly required to share the information fast and correctly. The technology to satisfy this need is web syndication and tagging in web 2.0. The web syndication makes feeds for another site or users to receive the content of web site. In addition, the tagging is the kernel of a information. Many internet users share rapidly the information through tag search. In this paper, we propose the efficient technique to improve the web 2.0 technology such as web syndication and tagging by using the data collection engine. Data collection engine has stored in a database, a user's Web site to use the information. and it has a user's Web site with access to updated data to collect. The experimental results show that our approach can improve the search speed up to 3.14 times better than the existing method and reduce the size of data up to 66% for building associated tags.

• Journal of KIISE:Databases
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• v.30 no.3
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• pp.320-335
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• 2003

Location-Based Services(LBS) give rise to location-based queries of which results depend on the locations of moving objects. One of important applications of LBS is to examine tracks of continuously moving objects. Moving objects databases need to provide 3-dimensional indexing for efficiently processing range queries on the movement of continuously changing positions. An extension of the 2-dimensional R-tree to include time dimension shows low space utilization and poor search performance, because of high overlap of index nodes and their dead space. To solve these problems, we propose a new R-tree based indexing technique, namely TR-tree. To increase storage utilization, we assign more entries to the past node by using the unbalanced splitting policy. If two nodes are highly overlapped, these nodes are forcibly merged. It is the forced merging policy that reduces the dead space and the overlap of nodes. Since big line segments can also affect the overlap of index nodes to be increased, big line segments should be clipped by the clipping policy when splitting overfull nodes. The TR-tree outperforms the 3DR-tree and TB-tree in all experiments. Particularly, the storage utilization of the TR-tree is higher than the R-tree and R*-tree.

• Journal of Korea Multimedia Society
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• v.14 no.10
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• pp.1348-1364
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• 2011

As the existing edutainment contents for children are mostly comprised of educational tools which unilaterally induce educatees to passively respond to them, the content-creating methodologies in terms of which active and voluntary learning is made possible is urgently needed. In this paper, we present the implementation of the tangible 'electronic dice' interface as an interactive tool for behavior-based edutainment contents, and propose a methodology for developing edutainment contents for children by utilizing the recognition technique of hand movement based on depth-image information. Also proposed in the paper are an authoring and management tool of learning quizzes that allows educators to set up and manage their learning courseware, and a log analysis system of learning achievement for real-time monitoring of educational progress. The behavior-based tangible interface and edutainment contents that we propose provide the easy-to-operate interaction with a real object, which augments educatees' interest in learning, thus leading to their active and voluntary attitude toward learning. Furthermore, The authoring and management tool and log analysis system allow us to construct learning programs by children's achievement level and to monitor in real-time the learning development of children educatees by understanding the situation and behavior of their learning development from the analytic results obtained by observing the processes of educatees' solving problems for themselves, and utilizing them for evaluation materials for lesson plans.

• Journal of Astronomy and Space Sciences
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• v.20 no.4
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• pp.339-350
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• 2003

Engineering qualification model payload for a communications and broadcasting satellite(CBS) was developed by ETRI from May, 2000 to April, 2003. For. the purpose of functional test and verification of the payload, a real-time hardware-in-the-loop(HITL) CBS simulator(CBSSIM) was also developed. We assumed that the spacecraft platform for the CBSSIM is a geostationary communication satellite using momentum bias three-axis stabilization control technique based on Koreasat. The payload hardware is combined with CBSSIM via Power, Command and Telemetry System(PCTS) of Electrical Ground Support Equipment(EGSE). CBSSIM is connected with PCTS by TCP/IP and the payload is combined with PCTS by MIL-STD-1553B protocol and DC harness. This simulator runs under the PC-based simulation environment with Windows 2000 operating system. The satellite commands from the operators are transferred to the payload or bus subsystem models through the real-time process block in the simulator. Design requirements of the CBSSIM are to operate in real-time and generate telemetry. CBSSIM provides various graphic monitoring interfaces and control functions and supports both pre-launch and after-launch of a communication satellite system. In this paper, the HITL simulator system including CBSSIM, communications payload and PCTS as the medium of interface between CBSSIM and communications payload will be described in aspects of the system architecture, spacecraft models, and simulator operation environment.

• The KIPS Transactions:PartD
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• v.11D no.5
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• pp.1167-1176
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• 2004

Along the advent of Internet technology, the computing environment has been considerably changed in many application domains. Especially, a lot of researches for e-Logistics have been done for the last 3 years. The e-Logistics means the virtual business activity and service architecture among the logistics companies based on the Internet technology. To construct effectively the e-Logistics framework, researches on the development of the Moving Object Technology(MOT) including GPS and GIS with spatiotemporal databases technique so far has been done The Moving Object Technology stands for the efficient management for the spatiotemporal objects such as vehicles, airplanes, and vessels which change continuously their spatial location along with time flows. However, most systems manage just only the location information detected lately by many reasons so that the uncertainty processing for the past and future location of the moving objects is still very hard. In this paper, we propose the moving object uncertainty model and system design for e-Logistics applications. The MOMS architecture in e-Logistics is suggested and the detailed explain of sub-systems including the uncertainty processor of moving objects is described. We also explain the comprehensive examples of MOMS and uncertainty processing in Delivery Parcel Application that is one of major application of e-Logistics domain.

• Korean Security Journal
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• no.12
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• pp.117-147
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• 2006

This study aims to propose efficient way to operate the security guarding system from the perspective of administration, policy, law, institution and operation as to the private security guarding system as the Korean security guarding system needs multifaced analysis and measure to ensure efficient operation. The growth strategy has to be restructured and segmentation market needs to be driven in order to cope with the changing conditions of company from the perspective of administration. And private security guarding service companies must refrain from excessive competition while improving the contracting method such as minimum price bidding, etc. From the perspective of policy, the functions of relevant organizations such as the National Police Agency, security association, etc, and mutual cooperation must expand. Also, the profit generation event needs to be privatized and the more positive perception toward the private security guarding service is necessary. In addition, security exhibition and seminar can be expanded to lay the groundwork for the advancement of private security system. From the legal and institutional perspective, the security guarding service related law must be revised and the certification system must b introduced to cope with the changing requirement. The security guarding instructor system must be strengthened to ensure a faithful and earnest implementation of duty to instruct, supervise and educate security guarding personnel. From the perspective of security guarding system's operation, professional security technique must be introduced and applied, and the volunteer application system must be established. In addition, standard 'security guarding manual' must be crafted, and the equipment for security guarding must be modernized to ensure an efficient operation of private security guarding services.

• Journal of Convergence for Information Technology
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• v.10 no.10
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• pp.1-8
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• 2020

The need for storage, management, and retrieval techniques for alternative data has emerged as technologies based on data generated from business activities conducted by enterprises have emerged as the key to business success in recent years. Existing big data platform systems must load a large amount of data generated in real time without delay to process unstructured data, which is an alternative data, and efficiently manage storage space by utilizing a deduplication system of different storages when redundant data occurs. In this paper, we propose a multi-layer distributed data deduplication process system using the similarity of the Cuckoo hashing filter technique considering the characteristics of big data. Similarity between virtual machines is applied as Cuckoo hash, individual storage nodes can improve performance with deduplication efficiency, and multi-layer Cuckoo filter is applied to reduce processing time. Experimental results show that the proposed method shortens the processing time by 8.9% and increases the deduplication rate by 10.3%.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.42 no.2 s.332
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• pp.61-74
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• 2005

Digital Multimedia Broadcasting(DMB) is a reliable multi-service system for reception by mobile and portable receivers. DMB system allows interference-free reception under the conditions of multipath propagation and transmission errors using COFDM modulation scheme, simultaneously, needs powerful channel error's correction ability. Viterbi Decoder for DMB receiver uses punctured convolutional code and needs lots of computations for real-time operation. So, it is desired to design a high speed and low-power hardware scheme for Viterbi decoder. This paper proposes a combined add-compare-select(ACS) and path metric normalization(PMN) unit for computation power. The proposed PMN architecture reduces the problem of the critical path by applying fixed value for selection algorithm due to the comparison tree which has a weak point from structure with the high-speed operation. The proposed ACS uses the decomposition and the pre-computation technique for reducing the complicated degree of the adder, the comparator and multiplexer. According to a simulation result, reduction of area $3.78\%$, power consumption $12.22\%$, maximum gate delay $23.80\%$ occurred from punctured viterbi decoder for DMB system.