• 제목/요약/키워드: Impact Safety

검색결과 2,652건 처리시간 0.033초

Breast Conserving Therapy and Quality of Life in Thai Females: a Mixed Methods Study

  • Peerawong, Thanarpan;Phenwan, Tharin;Supanitwatthana, Sojirat;Mahattanobon, Somrit;Kongkamol, Chanon
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권6호
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    • pp.2917-2921
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    • 2016
  • Background: To explore factors that influence quality of life (QOL) in patients receiving breast conserving therapy (BCT). Materials and Methods: In this sequential mixed methods study, 118 women from Songklanagarind Hospital were included. We used participants' characteristics, Body Image Scale (BIS), and Functional Assessment of Cancer Therapy with the Breast Cancer Subscale (FACT-B) for analysis. The BIS transformed into presence of body image disturbance (BID). Factors that influenced QOL were determined by stepwise multiple linear regression. Forty-one participants were selected for qualitative analysis. Our female researcher performed the semi-structured interviews with questions based on the symbolic interaction theory. Final codes were analysed using thematic analysis along with investigator triangulation methods. Results: Ninety percent had early stage breast cancer with post-completed BCT, for an average of 2.7 years. The median BIS score and FACT-B score were 2 (IQR=10) and 130 (IQR=39). In the regression analysis, an age of more than 50 years and BID were significant factors. As for the value of conserved breasts, two themes emerged: a conserved breast is an essential part of a participant's life and also the representation of her womanhood; the importance of a breast is related to age. Conclusions: Body image influenced QOL in post BCT participants. The conserved breasts also lead to positive and better impact on their body image as an essential part of their life.

Analysis of the dynamic confining effect of CRAC short column under monotonic loadings

  • Wang, Changqing;Xiao, Jianzhuang
    • Structural Engineering and Mechanics
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    • 제74권3호
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    • pp.351-363
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    • 2020
  • Based on the dynamic tests of recycled aggregate concrete (RAC) short columns confined by the hoop reinforcement, the dynamic failure mechanism and the mechanical parameters related to the constitutive relation of confined recycled aggregate concrete (CRAC) were investigated thoroughly. The fracturing sections were relatively flat and smooth at higher strain rates rather than those at a quasi-static strain rate. With the increasing stirrup volume ratio, the crack mode is transited from splitting crack to slipping crack constrained with large transverse confinement. The compressive peak stress, peak strain, and ultimate strain increase with the increase of stirrup volume ratio, as well as the increasing strain rate. The dynamic confining increase factors of the compressive peak stress, peak strain, and ultimate strain increase by about 33%, 39%, and 103% when the volume ratio of hoop reinforcement is increased from 0 to 2%, but decrease by about 3.7%, 4.2%, and 9.1% when the stirrup spacing is increased from 20mm to 60mm, respectively. This sentence is rephrased as follows: When the stirrup volume ratios are up to 0.675%, and 2%, the contributions of the hoop confinement effect to the dynamic confining increase factors of the compressive peak strain and the compressive peak stress are greater than those of the strain rate effect, respectively. The dynamic confining increase factor (DCIF) models of the compressive peak stress, peak strain, and ultimate strain of CRAC are proposed in the paper. Through the confinement of the hoop reinforcement, the ductility of RAC, which is generally slightly lower than that of NAC, is significantly improved.

자동차의 A필러에 대한 강도 및 내구성 해석을 통한 융합 연구 (A Convergence Study through Analysis of Strength and Durability on Automotive A-Pillar)

  • 오범석;조재웅
    • 한국융합학회논문지
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    • 제10권11호
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    • pp.297-302
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    • 2019
  • A필러는 주행 중 차량 전복시로 인하여 발생할 수 있는 충격을 완화시켜 탑승자의 신체 보호를 목적으로 안전성에 밀접한 관계가 있다. 그러므로 A필러는 다양한 동적 하중으로부터 이들 부품을 보호해야 한다. 이 제품을 만들기 전에 두 종류의 부품들을 설계하고 차량경량화를 위하여 두께가 조절된 제품을 분석함으로서 본 연구결과는 A필러의 강도 및 내구성에 기여할 수 있다고 사료된다. 본 연구결과를 자동차의 A 필러의 부품에 실제적으로 응용한다면 설계의 내구성 검증에 의하여 그 파손을 방지할 수 있다고 사료된다. 본 연구에서의 자동차의 A필러의 강도 및 내구성 해석에 관한 해석 및 설계 데이터를 이용함으로서 실제적인 자동차에서의 부품에 융합하여 그 미적 감각을 줄 수 있다.

CSR-BC와 Harmonized CSR-BC의 선체 전단 응력에 대한 비교 고찰 (A study on hull girder shear strength in bulk carriers for CSR and Harmonized CSR)

  • 박종민;이규호;이상복;신성광
    • 대한조선학회 특별논문집
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    • 대한조선학회 2015년도 특별논문집
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    • pp.46-49
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    • 2015
  • Common Structural Rules (CSR) about bulk carriers and double-hull oil tankers of International Association of Classification Societies (IACS) has been applied to ships contracted for construction since April 2006. By unifying each society's rules, the difference of opinion in the between shipyard and ship owners, classification was reduced, and CSR has been evaluated by rules the safety structure more enhanced. However, The CSR about the bulk carriers and double hull oil tankers, important design content standards, such as the local scantling calculation, static/dynamic load case and corrosion margin and etc., are different. Therefore in order to combine the CSR, the Harmonized CSR for bulk carriers and double hull oil tankers (H-CSR) was issued on 1, January, 2014, and will be apply to ships contracted for construction after 1st July 2015. It is necessary to verify the H-CSR to optimize the structural arrangement because effective date is not far off. In this study, we compared the impact by rule change for the hull girder shear strength of bulk carriers between CSR and H-CSR in respect of the yielding and buckling strength.

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사군자탕가미방(四君子湯加味方)이 난소적출 폐경 병태 모델의 자궁 및 난소 기능에 미치는 영향 (Effects of Sagunjatang-Gami on Uterine and Ovarian Function in the Ovariectomized Rat Postmenopause Model)

  • 맹유숙;최민선;안인숙;김동일
    • 대한한방부인과학회지
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    • 제25권4호
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    • pp.12-26
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    • 2012
  • Objectives: The purpose of this study is to examine the effects of Sagunjatang-Gami(SGJT) on uterine and ovarian function in the ovariectomized rat postmenopause model. Methods: SGJT was administered in ovariectomized Wister albino female rats for three month. After that, uterine weight, uterine index, serum estradiol-$17{\beta}$ levels and phosphorylation of ERK or AKT, and histological analysis of uterus were measured to assess the impact on uterine and ovarian function in ovariectomized rats. In addition, phosphorylation of $ER{\alpha}$, ERK, AKT by SGJT in MDA-MB-231 cells were measured. To identify safety of SGJT, the cell cytoxicity in MDA-MB-231 cells and serum GOT, GPT levels were measured in ovariectomized rats. Results: The results were as follows. 1. SGJT decreased the viability of MDA-MB-231 cells in a dose-dependent manner. 2. The level of serum GOT, GPT in SGJT-treated group showed significant decrease in comparison with control group. 3. Phosphorylation of $ER{\alpha}$, ERK, AKT by SGJT in MDA-MB-231 cells were increased. 4. Uterus index in SGJT-treated group showed significant increase in comparison with control group. The level of serum estradiol-$17{\beta}$ in SGJT-treated group showed significant increase in comparison with control group. Phosphorylation of ERK or AKT by SGJT in the uterus of ovariectomized rats was increased significantly. 5. Uterus index and the level of serum estradiol-$17{\beta}$ in SGJT-treated group increased at higher rates in comparison with estrogen-treated group. Conclusions: Taken together, we suggest that SGJT has been shown to be effective in preventing postmenopausal uterine and ovarian degeneration and curing postmenopausal low estrogen related symptoms.

태안군 이원면 육상오염원 배출수에서 분리한 그람음성균의 항생제 내성 특성 (Antimicrobial Resistance Characteristics of Gram-Negative Bacteria Isolated from Inland Pollution Sources in the Drainage Basin of Iwon-myeon (Taean-gun), South Korea)

  • 박보미;김민주;정연겸;박진일;유홍식;오은경
    • 한국수산과학회지
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    • 제54권4호
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    • pp.377-387
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    • 2021
  • Fecal contamination levels of discharge water from inland pollution sources were investigated in Iwon-myeon (Taean-gun), South Korea. Gram-negative bacteria were isolated during the investigation and the antimicrobial resistance patterns of the isolates were examined to estimate their impact on the coastal environment. The ranges of total coliform and fecal coliform of 12 samples from four major inland pollution sources were 79-490,000 MPN/100 mL and 2.0-490,000 MPN/100 mL, respectively, with the highest level of fecal contamination at Station No. 3. A total of 137 strains (14 genus) were isolated, of which 86 strains (62.8%) were Enterobacteriaceae. The identified isolates were as follows: Pseudomonas spp. (35 strains), Klebsiella spp. (20 strains), Serratia spp. (20 strains), and Escherichia spp. (19 strains). The isolated Gram-negative bacteria showed the highest antimicrobial resistance to ampicillin (81.8%), followed by amoxicillin/clavulanic acid (64.2%), ceftiofur (61.3%), and cefoxitin (59.1%). Antimicrobials in which less than 10% of isolates showed antimicrobial resistance were ciprofloxacin (3.6%) and gentamicin (2.2%). Resistance to one or more antimicrobials was observed in 121 strains (88.3%) and 84 strains (61.3%) showed a tendency for multiple antimicrobial resistance.

The Effect of Manual Physical Therapy on Improvement in the Range of Motion of Frozen Shoulder Patients: A Meta-Analysis of Cases in South Korea

  • Kim, Chan Myeong;Lee, Jong Kyung;Hwang, Jong Ha;Lee, Jae Kwang
    • The Journal of Korean Physical Therapy
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    • 제33권5호
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    • pp.211-216
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    • 2021
  • Purpose: The main purpose of this meta-analysis was to identify the degree of effect size and variables for the impact of manual physical therapy on the improvement in the range of motion of frozen shoulder patients. Methods: This study collected 8 studies published between 1st January 2010 and 31st December 2020. The analysis of the results verified 49 effect size data and the random effect model was chosen. Results: First, the full case showed the largest mean effect size of 2.485 (p<0.001). Second, the size of the effect based on manual therapy and modality therapy showed an effect size of 4.178 (p<0.001). Third, the outcome group included 6 variables. The external rotation (2.818) variable group showed the largest mean effect size, followed by internal rotation (2.748), flexion (2.643), abduction (2.356), and adduction (2.356). Six outcomes were significant and the mean effect sizes of all the varied groups were above large size. The number of participants showed a 20 or less effect size of 2.478 (p>0.737). The number of intervention periods showed 4 weeks 20 or more effect size of 2.782 (p>0.294). Finally, the 'Trim and Fill' result confirmed that the calibration effect size was 1.471 (p<0.001). Conclusion: This study verified that manual physical therapy had a substantial effect on the improvement of the range of motion of patients with frozen shoulders and that the effects were dependent on the methods of outcomes.

압축 벤토나이트 완충재의 역학 물성 평가 (Evaluation of Mechanical Properties for the Compacted Bentonite Buffer Materials)

  • 윤석;홍창호;김태현;김진섭
    • 한국지반공학회논문집
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    • 제37권10호
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    • pp.5-11
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    • 2021
  • 압축 벤토나이트 완충재는 원자력발전소에서 발생하는 고준위폐기물을 처리하기 위한 공학적방벽시스템의 가장 중요한 요소 중 하나이다. 압축 벤토나이트 완충재는 외부 하중이나 지하수 침투로부터 처분 용기를 보호하기에, 열-수리-역학적인 요구 조건을 충족하여야 한다. 이러한 완충재의 열-수리 물성에 관한 연구는 많이 진행되어 왔지만, 역학 물성 규명에 관한 연구는 많이 부족한 실정이다. 이러한 이유로, 본 연구에서는 건조밀도와 함수비에 따른 다양한 국내 압축 벤토나이트 시료를 조성하여 이에 대한 일축압축강도시험을 실시하였으며, 일축압축강도, 탄성계수, 그리고 포아송비를 도출하였다. 압축 벤토나이트의 일축압축강도와 탄성계수는 건조밀도에 따라 증가하였으며, 포아송비는 건조밀도가 증가할수록 약간 감소하는 것으로 나타났다. 일축압축강도, 탄성계수 및 포아송비는 건조밀도와 큰 상관 관계를 보였으나, 함수비와는 특별한 상관성을 나타내지는 않았다.

건조환경의 쾌적성과 미기후가 도시공간의 외부활동 지속에 미치는 영향 분석 (The Impact of Comfort of built Environment and Microclimate on Outdoor Activities in Urban Space)

  • 정윤남;이건원
    • 예술인문사회 융합 멀티미디어 논문지
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    • 제9권5호
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    • pp.565-575
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    • 2019
  • 본 연구는 물리환경 및 미기후, 쾌적성이 외부활동 지속에 미치는 영향 도출을 목적으로 한다. 본 연구에서는 외부활동 지속에 영향을 미치는 요소로 도시 내 물리환경, 물리환경에 대해 외부공간 활동자가 느끼는 쾌적성, 미기후, 미기후에 대해 외부공간 활동자가 느끼는 쾌적성 등을 중심으로 접근했다. 이에 대한 분석을 위해서 2017년 중 봄, 여름, 겨울과 같이 세 계절에 대해서 외부공간 활동자가 느끼는 다양한 쾌적도에 대한 설문조사를 수행하였다. 설문조사 응답자가 설문조사에 응답하고 있는 동안에 주변 장소의 미기후에 대한 측정을 실시하였다. 이렇게 구축된 자료를 이용하여 효과적인 분석수행을 위해서 로짓회귀분석을 이용하였다. 분석결과, 물리환경 쾌적성의 용이성 및 안전성과 기후환경 쾌적성의 온도, 바람, 일사량 쾌적성 등은 외부공간의 활동 지속도와 유의미한 관계를 맺고 있었다. 머물기 및 대화 행위 보다는 걷기와 쇼핑 행위가 물리적 환경 및 기후환경에 보다 예민하게 영향을 받는 요소임을 도출했다.

염소・불화수소 탱크로리 누출사고 시 이격거리 산정을 위한 산정표 및 산정식 개발 연구 (A Study on the Development of Calculation Tables and Formulas for Determining Separation Distance in Case of Cl2・HF Tank-lorry Leakage)

  • 전병한;김현섭;임상민;이주찬;이강산
    • 한국산학기술학회논문지
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    • 제22권4호
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    • pp.212-219
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    • 2021
  • 운송차량에 의한 화학사고는 매년 전체 화학사고의 20 %를 차지하지만 영향평가 정보를 알 수 없는 상황이 반복되어 사고대응 과정에서 어려움을 겪게 되는 문제점이 존재한다. 본 연구에서는 국내 사용량이 많고 사고 위험성이 높으며, 최근 7년간 사고 빈도가 높은 염소와 불화수소를 대상으로 탱크로리로 운반하는 과정에서 누출사고가 발생하였을 경우 현장에서 이격거리 산정을 위하여 활용될 수 있는 피해예측범위 산정표 및 산정식을 개발하였다. 화학물질의 누출속도와 기상조건 중 풍속, 온도에 따른 산정표를 조사하였으며, 산정표를 적용하기 힘든 특수한 상황에서는 산정식을 적용할 수 있도록 통계 프로그램 R을 사용하여 산정식을 도출하였다. 유관기관에서는 현장에서 연구에서 도출된 산정표 및 산정식을 활용하면 화학사고 피해 최소화 및 이격거리 설정, 주민대피 결정 등의 의사결정 측면에서 중요한 정보로써 사용할 수 있을 것으로 사료된다.