• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.103-108
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• 1999

The aim of the work described in this paper is to develop a complex underground acoustic system which detects and localizes the origin of an underground hammering sound using an array of hydrophones located about loom underground. Three different methods for the sound localization will be presented, a time-delay method, a power-attenuation method and a hybrid method. In the time-delay method, the cross correlation of the signals received from the array of sensors is used to calculate the time delays between those signals. In the power-attenuation method, the powers of the received signals provide a measure of the distances of the source from the sensors. In the hybrid method, both informations of time-delays and power-ratios are coupled together to produce better performance of position estimation. A new acoustic imaging technique has been developed for improving the hybrid method. This new acoustic imaging method shows the multi-dimensional distribution of the normalized cost function, so as to indicate the trend of the minimizing direction toward the source location. For each method the sound localization is carried out in three dimensions underground. The distance between the true and estimated origins of the source is 28m for a search area of radius 250m.

• Molecules and Cells
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• v.44 no.11
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• pp.851-860
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• 2021

Label-free optical diffraction tomography (ODT), an imaging technology that does not require fluorescent labeling or other pre-processing, can overcome the limitations of conventional cell imaging technologies, such as fluorescence and electron microscopy. In this study, we used ODT to characterize the cellular organelles of three different stem cells-namely, human liver derived stem cell, human umbilical cord matrix derived mesenchymal stem cell, and human induced pluripotent stem cell-based on their refractive index and volume of organelles. The physical property of each stem cell was compared with that of fibroblast. Based on our findings, the characteristic physical properties of specific stem cells can be quantitatively distinguished based on their refractive index and volume of cellular organelles. Altogether, the method employed herein could aid in the distinction of living stem cells from normal cells without the use of fluorescence or specific biomarkers.

• Investigative Magnetic Resonance Imaging
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• v.15 no.1
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• pp.57-66
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• 2011

Purpose : A new inhomogeneity correction method based on two-point Dixon sequence is proposed to obtain water and fat images at 0.35T, low field magnetic resonance imaging (MRI) system. Materials and Methods : Joint phase-magnitude density function (JPMF) is obtained from the in-phase and out-of-phase images by the two-point Dixon method. The range of the water signal is adjusted from the JPMF, and 3D inhomogeneity map is obtained from the phase of corresponding water volume. The 3D inhomogeneity map is used to correct the inhomogeneity field iteratively. Results : The proposed water-fat imaging method was successfully applied to various organs. The proposed 3D inhomogeneity correction algorithm provides good performances in overall multi-slice images. Conclusion : The proposed water-fat separation method using JPMF is robust to field inhomogeneity. Three dimensional inhomogeneity map and the iterative inhomogeneity correction algorithm improve water and fat imaging substantially.

• Imaging Science in Dentistry
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• v.37 no.2
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• pp.69-77
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• 2007

Purpose: To evaluate the accuracy of the imaging reformation of cone beam computed tomography for the assessment of bone defect healing in rat model. Materials and Methods: Sprague-Dawley strain rats weighing about 350 gms were selected. Then critical size bone defects were done at parietal bone with implantation of collagen sponge. The rats were divided into seven groups of 3 days, 1 week, 2 weeks, 3 weeks, 4 weeks, 6 weeks, and 8 weeks. The healing of surgical defect was assessed by multi planar reconstruction (MPR) images and three-dimensional (3-D) images of cone beam computed tomography, compared with soft X-ray radiograph and histopathologic examination. Results: MPR images and 3-D images showed similar reformation of the healing amount at 3 days, 1 week, 2 weeks, and 8 weeks, however, lower reformation at 3 weeks, 4 weeks, and 6 weeks. According to imaging-based methodologies, MPR image revealed similar reformation of the healing amount than 3-D images compare with soft X-ray image. Among the four threshold values for 3-D images, 400-500 HU revealed similar reformation of the healing amount. Histopathologic examination confirmed the newly formed trabeculation correspond with imaging-based methologies. Conclusion: MPR images revealed higher accuracy of the imaging reformation of cone beam computed tomography and cone beam computed tomography is a clinically useful diagnostic tool for the assessment of bone defect healing.

• Investigative Magnetic Resonance Imaging
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• v.21 no.3
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• pp.131-138
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• 2017

Purpose: To optimize the timing of scans using cardiac magnetic resonance contrast-enhanced timing robust angiography (CMR-CENTRA) for electroanatomic mapping (EAM) of the right atrium (RA) and left atrium (LA) in patients with atrial fibrillation (AF). Materials and Methods: Fifty patients with AF (38 men; mean age, $59.6{\pm}9.3years$) underwent CMR-CENTRA in preparation for EAM. The CMR-CENTRA data were acquired at five different scan times: 0 seconds, 5 seconds, 10 seconds, 15 seconds, and 20 seconds after an intravenous injection of contrast media. To evaluate the degree of contrast enhancement, right atrial relative contrast (RA-RC) and left atrial relative contrast (LA-RC) on the CMR-CENTRA scans were assessed at each time point. The three-dimensional (3D) reconstruction of the RA and LA for the EAM system was performed using the CMR-CENTRA data. Results: A CMR-CENTRA at a scan time of 10 seconds showed significantly greater LA-RC (P < 0.05) compared with all other scan times. A CMR-CENTRA at a scan time of 15 seconds showed significantly greater RA-RC (P < 0.05) compared with all other scan times. In the 3D reconstruction of the RA, the success rates of CMR-CENTRA at scan times of 10 seconds and 15 seconds were 18% and 100%, respectively. In the 3D reconstruction of the LA, the success rates of CMR-CENTRA at 10- and 15-second scan times were 100%. Conclusion: The CMR-CENTRA data acquired at 15 seconds after the injection of contrast media is appropriate for the preparation of an EAM system that is focused on the RA and LA in patients with AF.

• Imaging Science in Dentistry
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• v.33 no.3
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• pp.151-159
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• 2003

Purpose: The purpose of this study is to evaluate the effectiveness and usefulness of newly developed personal computer-based software to eliminate the linear artifacts by the metal restorations. Materials and Methods: A 3D CT image was conventionally reconstructed using ADVANTAGE WINDOWS 2.0 3D Analysis software (GE Medical System, Milwaukee, USA) and eliminated the linear artifacts manually. Next, a 3D CT image was reconstructed using V-works 4.0/sup TM/(Cybermed Inc., Seoul, Korea) and the linear artifacts eliminated manually in the axial images by a skillful operator using a personal computer. A 3D CT image was reconstructed using V-works 4.0/sup TM/(Cybermed Inc., Seoul, Korea) and the linear artifacts were removed using a simplified algorithm program to eliminate the linear artifacts automatically in the axial images using a personal computer, abbreviating the manual editing procedure. Finally, the automatically edited reconstructed 3D images were compared to the manually edited images. Results and Conclusion: We effectively eliminated the linear artifacts automatically by this algorithm, not by the manual editing procedures, in some degree. But programs based on more complicated and accurate algorithms may lead to a nearly flawless elimination of these linear artifacts automatically.

• Imaging Science in Dentistry
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• v.35 no.3
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• pp.167-173
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• 2005

Purpose : To investigate the relationship between three-dimensional (3D) bone imaging parameters and trabecular strength in the mandible. Materials and Methods : Bone specimens were obtained from the mandibles of five male pigs weighing around 110 kg each. Of those, 43 samples were selected for 3D analysis and measured by micro-computed tomography. The five morphometric parameters were trabecular thickness (Tb.Th), bone specific surface (BS/BV), percent bone volume (BV/TV), structure model index (SMI) and degree of anisotropy (DA). Through destructive mechanical testing, strength parameters were obtained. Results : BV/TV, SMI, BS/BV, and Tb.Th showed significant correlations with strength parameters. DA did not show any correlation with the other parameters. In multiple linear regression analysis, BV/TV alone explained $43\%$ of the variance in Young's modulus. By stepwise inclusion of SMI, the variance in the Young's modulus was better explained up to $52\%$. Conclusions : Predicting trabecular strength in the mandible through architectural analysis would be possible. Further study is needed to establish the tendency and variety of trabecular architecture and strength according to the locations within the mandible.

• Imaging Science in Dentistry
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• v.43 no.3
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• pp.163-169
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• 2013

Purpose: Tonsilloliths are calcifications found in the crypts of the palatal tonsils and can be detected on routine panoramic examinations. This study was performed to highlight the benefits of cone-beam computed tomography (CBCT) in the diagnosis of tonsilloliths appearing bilaterally on panoramic radiographs. Materials and Methods: The sample group consisted of 7 patients who had bilateral radiopaque lesions at the area of the ascending ramus on panoramic radiographs. CBCT images for every patient were obtained from both sides of the jaw to determine the exact locations of the lesions and to rule out other calcifications. The calcifications were evaluated on the CBCT images using Ez3D2009 software. Additionally, the obtained images in DICOM format were transferred to ITK SNAP 2.4.0 pc software for semiautomatic segmentation. Segmentation was performed using contrast differences between the soft tissues and calcifications on grayscale images, and the volume in mm3 of the segmented three dimensional models were obtained. Results: CBCT scans revealed that what appeared on panoramic radiographs as bilateral images were in fact unilateral lesions in 2 cases. The total volume of the calcifications ranged from 7.92 to $302.5mm^3$. The patients with bilaterally multiple and large calcifications were found to be symptomatic. Conclusion: The cases provided the evidence that tonsilloliths should be considered in the differential diagnosis of radiopaque masses involving the mandibular ramus, and they highlight the need for a CBCT scan to differentiate pseudo- or ghost images from true bilateral pathologies.

• Imaging Science in Dentistry
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• v.46 no.2
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• pp.77-85
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• 2016

Purpose: To analyze the relative position of the mandibular foramina (MnFs) in patients diagnosed with skeletal class III malocclusion. Materials and Methods: Computed tomography (CT) images were collected from 85 patients. The vertical lengths of each anatomic point from the five horizontal planes passing through the MnF were measured at the coronoid process, sigmoid notch, condyle, and the gonion. The distance from the anterior ramus point to the posterior ramus point on the five horizontal planes was designated the anteroposterior horizontal distance of the ramus for each plane. The perpendicular distance from each anterior ramus point to each vertical plane through the MnF was designated the horizontal distance from the anterior ramus to the MnF. The horizontal and vertical positions were examined by regression analysis. Results: Regression analysis showed the heights of the coronoid process, sigmoid notch, and condyle for the five horizontal planes were significantly related to the height of the MnF, with the highest significance associated with the MnF-mandibular plane (coefficients of determination ($R^2$): 0.424, 0.597, and 0.604, respectively). The horizontal anteroposterior length of the ramus and the distance from the anterior ramus point to the MnF were significant by regression analysis. Conclusion: The relative position of the MnF was significantly related to the vertical heights of the sigmoid notch, coronoid process, and condyle as well as to the horizontal anteroposterior length of the ascending ramus. These findings should be clinically useful for patients with skeletal class III mandibular prognathism.

• Journal of Digital Contents Society
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• v.11 no.4
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• pp.425-431
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• 2010

This study explored the effects and the effectiveness of the new method of 3D FIESTA by making quantitative comparison with the conventional 3D FSE method which is frequently employed on patients with sudden hearing loss in clinical settings. For this study, 3D FSE images acquired with 3.0T MR scanner and T2-weighted axial plane 3D FIESTA images were respectively taken from 40 patients diagnosed with Sensorineural Hearing Loss (SSHL). When obtaining those images, sagittal reconstructions oriented perpendicular to the nerve were performed in order to get sagittal images of both right and left internal auditory canal. The findings showed that both SNR and CNR were higher among the group to whom the 3D FIESTA method was applied than the group to whom the conventional 3D FSE method was applied.