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Deuteromethylactin B from a Freshwater-derived Streptomyces sp.

  • Shaikh, Anam F.;Elfeki, Maryam;Landolfa, Samantha;Tanouye, Urszula;Green, Stefan J.;Murphy, Brian T.
    • Natural Product Sciences
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    • v.21 no.4
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    • pp.261-267
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    • 2015

  • Compared to their terrestrial and marine counterparts, little is known about the capacity of freshwater-derived actinomycete bacteria to produce novel secondary metabolites. In the current study, we highlight the disparities that exist between cultivation-independent and -dependent analyses of actinomycete communities from four locations in Lake Michigan sediment. Furthermore, through phylogenetic analysis of strains isolated from these locations, we identified a Streptomyces sp., strain B025, as being distinct from other Streptomyces spp. isolated from sediment. Upon fermentation this strain produced a rare class of eight-membered lactone secondary metabolites, which have been for their antitumor properties. We used spectroscopic and chemical derivitization techniques to characterize octalactin B (1) in addition to its corresponding novel, unnatural degradation product (2).

  • https://doi.org/10.20307/nps.2015.21.4.261 인용 PDF KSCI

Ultrasonics and electromagnetics for a wireless corrosion sensing system embedded in structural concrete

  • Hietpas, K.;Ervin, B.;Banasiak, J.;Pointer, D.;Kuchma, D.A.;Reis, H.;Bernhard, J.T.
    • Smart Structures and Systems
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    • v.1 no.3
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    • pp.267-282
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    • 2005

  • This work describes ongoing development of an embedded sensor system for the early detection and prevention of deterioration of reinforcing steel tendons within reinforced concrete. These devices will evaluate the condition of the steel tendon using ultrasonic techniques and then wirelessly transmit this data to the outside world without human intervention. The ultrasonic transducers and the interpretation of the sensed signals that allow detection and prognosis of tendon condition are detailed. Electrical characterization of concrete mixtures used in bridge construction is conducted and a wideband microstrip antenna is designed and fabricated to operate between 2.4 and 2.5 GHz when embedded in such a medium. Simulations and measurements of the embedded antenna element are presented. Transceiver selection and implementation are discussed as well as future work in operational protocols, sensor networking, and power sources. By implementing commercially available off-the-shelf components whenever possible, these devices have the potential to save millions of dollars a year in evaluation, repair and replacement of reinforced concrete.

  • https://doi.org/10.12989/sss.2005.1.3.267 인용