• 대한소아치과학회지
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• 제45권2호
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• pp.137-143
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• 2018

본 실험의 목적은 초기 우식 부위에 레진 침투법과 불소 적용 후 탈회 저항성을 비교하기 위함이다. 인공 우식을 유발한 시편을 대조군, 1.23% 산성불화인산염(Acidulated phosphate fluoride(APF))군, 레진 침투군으로 분류하고 각 재료를 적용 후 재탈회시켰다. 이후 공초점 레이저 현미경(Confocal Laser Scanning Microscope(CLSM))을 이용하여 탈회 깊이를 측정하였고 주사전자현미경(SEM)을 이용하여 법랑질 표면 거칠기를 관찰하였다. CLSM을 이용하여 탈회 깊이를 측정하였을 때 대조군, 1.23% 산성불화인산염군, $Icon^{(R)}$ caries infiltrant군 순으로 감소하였다. 탈회 깊이는 1.23% 산성불화인산염군, $Icon^{(R)}$ caries infiltrant군이 대조군에 비해서는 유의성 있는 차이를 보이지만 두 군 간의 차이가 없었다(p < 0.05). 표면거칠기는 대조군에서 매우 거칠고 표면이 불규칙한 양상을 보였고 1.23% 산성불화인산염군, $Icon^{(R)}$ caries infiltrant 군으로 갈수록 표면 거칠기와 불규칙성은 감소하였다.

• Restorative Dentistry and Endodontics
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• 제47권3호
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• pp.29.1-29.10
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• 2022

Objectives: This study aimed to investigate the anti-erosive/abrasive effect of resin infiltration of previous deproteinized dentin. Materials and Methods: Dentin slabs were randomly assigned to 3 groups (n = 15): Control (no deproteinization; no resin infiltrant applied), RI (no deproteinization; resin infiltrant applied), and DRI (deproteinization; resin infiltrant applied). After undergoing the assigned treatment, all slabs were subjected to an in vitro cycling model for 5 days. The specimens were immersed in citric acid (0.05 M, pH = 3.75; 60 seconds; 3 times/day) and brushed (150 strokes). Between the challenges, the specimens were exposed to a remineralizing solution (60 minutes). The morphological alterations were analyzed by mechanical profilometry (㎛) and scanning electron microscopy (SEM). Data were submitted to one-way analysis of variance (ANOVA) and Tukey tests (p < 0.05). Results: Control and RI groups presented mineral wear and did not significantly differ from each other (p = 0.063). DRI maintained a protective layer preserving the dentin (p < 0.001). After erosive/abrasive cycles, it was observed that in group RI, only 25% of the slabs partially evidenced the presence of the infiltrating, while, in the DRI group, 80% of the slabs presented the treated surface entirely covered by a resin-component layer protecting the dentin surface as observed in SEM images. Conclusions: The removal of the organic content allows the resin infiltrant to efficiently protect the dentin surface against erosive/abrasive lesions.

• 한국치위생학회지
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• 제19권2호
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• pp.173-181
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• 2019

Objectives: The resin infiltration technique is a promising alternative therapy for arresting the early dental caries. However, there are very few reports on the safety and biocompatibility of this technique. We evaluated various properties of resin infiltrant (RI) based on a triethylene glycol dimethacrylate (TEGDMA).The water sorption (Wsp) and water solubility (Wsl) was assessed. Additionally, the cytotoxicity of RI against both animal and human fibroblast cell lines was investigated. Methods: The RI of the $Icon^{(R)}$, the first product developed for resin infiltration, is mainly composed of TEGDMA in the resin matrix. The Wsp and Wsl for the RI were measured in accordance with ISO 4049 specifications. Fourier-transform infrared spectroscopy (FTIR) was used for analyzing the polymerization before and after curing of RI. The cytotoxicity of RI against the mouse fibroblasts (L929) and human gingival fibroblasts (hTERT-hNOF) was evaluated using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay and the data were analyzed using one-way analysis of variance. Results: Wsp and Wsl of the RI specimens were $53.37{\mu}g/mm^3$ and $10.6{\mu}g/mm^3$, respectively. FTIR analysis revealed a slightly higher degree of curing with longer irradiation time. The degree of conversion for RI was high (80.9%) after 40 seconds of light curing. There was a significant decrease in the viability of L929 and hTERT-hNOF cells at RI extraction solution concentrations above 50%, respectively, compared to that in the negative control (p< 0.05). Conclusions: Even though the RI exhibited positive effect on the early prevention of dental caries, the clinicians should also consider the toxicity of RI on periodontal tissues.

• 대한치과교정학회지
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• 제44권4호
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• pp.195-202
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• 2014

Objective: A low-viscosity resin (infiltrant) was used to inhibit the progression of white spot lesions (WSLs) and resolve associated esthetic issues. An alternative pretreatment was explored to increase the pore volume of the surface layer of the WSLs. Also, the penetration effects of the infiltrant were evaluated for various pretreatments. Methods: Sixty two artificial lesions were fabricated on bovine teeth. As a positive control, 15% HCl gel was applied for 120 seconds. Further, 37% $H_3PO_4$ gel was applied for 30 seconds using three methods. The samples were divided as follows: $H_3PO_4$ only group, $H_3PO_4$ sponge group, and $H_3PO_4$ brush group. The acid was gently rubbed with the applicators (i.e., a sponge or brush) throughout the application time. To compare the effects of resin infiltration, twenty paired halves of specimens were treated with an infiltrant (ICON$^{(R)}$). Results: Thicknesses of the removed surface layers and infiltrated areas were evaluated by confocal laser scanning microscope. The positive control and the 37% $H_3PO_4$ brush group failed to show significant differences in the removed thickness (p > 0.05); however, the mean percentage of the infiltrated area was higher in the 37% $H_3PO_4$ brush group ($84.13{\pm}7.58%$%) than the positive control ($63.51{\pm}7.62%$, p < 0.001). Scanning electron microscope observations indicate higher pore volumes for the 37% $H_3PO_4$ brush group than for the positive control. Conclusions: Application of 37% $H_3PO_4$ with a brush for 30 seconds increased the pore volume of WSL surface layers and the percentage of infiltrated areas in comparison to the use of 15% HCl for 120 seconds.