• Bulletin of the Korean Chemical Society
• /
• v.15 no.6
• /
• pp.432-436
• /
• 1994

Monomeric rhodium and iridium-diaryltetrazene complexes $Cp^*$M(RNN=NNR)($Cp^*$=1,2,3,4,5-pentamethylcyclope ntadienyl; M=Rh, Ir; R=Ph, 4-tolyl) have been synthesized from [$Cp^*MCl_2]_2$(M=Rh, Ir) and 2 equiv. of $[Li(THF)_x]_2(RN_4$R) in benzene. We have determined the crystal structure of (${\eta}^5$-pentamethylcyclopentadienyl)diphenyltetrazene iridium by using graphite-monochromated Mo-$K_a$ radiation. The compound was crystallized in the monoclinic space group $P2_{1/c}$ with a=13.781(3), b=9.035(l), c=17.699(3) ${\AA}$, and ${\beta}=111.93(l)^{\circ}$. An X-ray crystal structure of complex 1 showed a short N(2)-N(3) distance ($1.265 {\AA}$) consistent with the valence tautomer A with Ir(III) rather than Ir(I). All complexes are highly colored and decompose on irradiation at 254 nm. Electrochemical studies show that complex 1 displays a quasi-reversible reduction.

• Clinical and Experimental Pediatrics
• /
• v.46 no.7
• /
• pp.679-686
• /
• 2003

Purpose : Ataxia telangiectasia mutated(ATM) is involved in DNA damage responses at different cell cycle checkpoints, and signalling pathways associated with regulation of apoptosis in response to ionizing radiation(IR). However, the signaling pathway that underlies IR-induced apoptosis in ATM cells has remained unknown. The purpose of this study was, therefore, to investigate the apoptotic pathway that underlies IR-induced apoptosis in a CT-26 cells expressing dominant negative ATM (DN-ATM). Methods : We generated a replication-deficient recombinant adenovirus encoding the DN-ATM(Ad/DN-ATM) or control adenovirus encoding no transgene(Ad/GFP) and infected adenovirus to CT-26 cells. After infection, we examined apoptosis and apoptotic pathway by [$^3H$]-thymidine assay, DNA fragmentation, and Western immunoblot analysis. Results : DN-ATM gene served as the creation of AT phenotype in a CT-26 cells as revealed by decreased cell proliferations following IR. In addition, IR-induced apoptosis was regulated through the reduced levels of the anti-apoptotic protein Bcl-2, the increased levels of the apoptotic protein Bax, and the activation of caspase-9, caspase-3, and PARP. Conclusion : These results indicate that the pathway of IR-induced apoptosis in CT-26 cells expressing DN-ATM is mediated by mitochondrial signaling pathway involving the activation of caspase 9, caspase 3, and PARP.

• Korean Journal of Soil Science and Fertilizer
• /
• v.8 no.4
• /
• pp.183-188
• /
• 1975

Effects of air temperature and 50% shading for 20 days at each growth stages (from 33days before heading, from heading and from 20days after heading) on the productivity of Tongil (IR667-Suweon 214) and Jinheung rice (Oriza sativa.) were as follows. 1. Shading decreased yield by 48, 98 and 18% for Tongil and 73.71 and 12% for Jinheung during ear formation, heading and milky stage, respectively. 2. Shading most severely affected filled-grain ratio in both varieties except shading during milky stage of Jinheung that more affected grain weight. 3. Optimum mean air temperature for maximum crop growth rate appears to be $25^{\circ}C$ and clitical temperature $22^{\circ}C$ for Tongil but these for Jinheung seem to be lower. Solar radiation greater than $300cal/cm^2$ day appears to be enough. 4. Maximum crop growth rate of Tongil always advanced that of Jinheung. 5. Tropical Tongil variety appeared to be more tolerant to high temperature and low solar radiation before heading than temperate Jinheung. Thus Tongil will be more productively adapted to the high temperature-low solar radiation period in rice season which mostly overlaps with ear formation stage.

• Molecules and Cells
• /
• v.41 no.4
• /
• pp.362-372
• /
• 2018

High mobility group box 2 (HMGB2) is an abundant, chromatin-associated, non-histone protein involved in transcription, chromatin remodeling, and recombination. Recently, the HMGB2 gene was found to be significantly downregulated during senescence and shown to regulate the expression of senescent-associated secretory proteins. Here, we demonstrate that HMGB2 transcription is repressed by p21 during radiation-induced senescence through the ATM-p53-p21 DNA damage signaling cascade. The loss of p21 abolished the downregulation of HMGB2 caused by ionizing radiation, and the conditional induction of p21 was sufficient to repress the transcription of HMGB2. We also showed that the p21 protein binds to the HMGB2 promoter region, leading to sequestration of RNA polymerase and transcription factors E2F1, Sp1, and p300. In contrast, NF-Y, a CCAAT box-binding protein complex, is required for the expression of HMGB2, but NF-Y binding to the HMGB2 promoter was unaffected by either radiation or p21 induction. A proximity ligation assay results confirmed that the chromosome binding of E2F1 and Sp1 was inhibited by p21 induction. As HMGB2 have been shown to regulate premature senescence by IR, targeting the p21-mediated repression of HMGB2 could be a strategy to overcome the detrimental effects of radiation-induced senescence.

• Progress in Superconductivity and Cryogenics
• /
• v.4 no.2
• /
• pp.68-72
• /
• 2002

This work investigates the transient cooling characteristics of an Infrared (IR) detector cryochamber, which has a critical effect on the cooling load. The current thermal modeling considers the conduction heat transfer through a cold well. the gaseous conduction due to outgassing. and the radiation heat transfer. The transient cooling Performance. i.e. the penetration depth and cooling load, is determined using a finite difference method. It is found that the penetration depth increases as the bore conductivity increases. Gaseous conduction and radiation hardly affect the penetration depth. The transient cooling load increases as the bore conductivity increases. The effects of gaseous conduction and radiation on transient heat transfer are weak at initial stages of cooling. However, their effects become significant as the cooling Process Proceeds.

• Journal of the Korean Society of Radiology
• /
• v.13 no.1
• /
• pp.39-44
• /
• 2019

Radiation safety management is being considered very important since radioactive isotopes such as Co-60 and Ir-192 are widely used in fields such as non-destructive test(NDT). In this study, the applicability of Mercury(II) Iodide($HgI_2$) source for tracing system was evaluated. To make sure the unit cell sensor's reliability, we evaluated the electrical properties of the sensor made with $HgI_2$, and then position dependence of the sensor was analyzed and compared with the dose distribution from the planning system. As a result of the evaluation, high reliability of the sensor was shown through the linearity of R-sq > 0.990 and reproducibility of CV < 0.015. In the position dependence evaluation, the maximum value was measured at the isocenter of the sensor and gradually decreased according to the distance. However, the dose distribution data from the planning system was turned out that has difference with that of the sensor up to 30%. This seems to come from the difference between single-point measuring based planning system and area measuring based sensor.

• Bulletin of the Korean Chemical Society
• /
• v.31 no.4
• /
• pp.910-914
• /
• 2010

A novel synthetic route has been developed to prepare $\alpha$-cobalt hydroxide with intercalated nitrate anions. It was successfully synthesized by $\gamma$-ray irradiation under simple conditions, i.e., air atmosphere, without base. Under $\gamma$-ray irradiation, it leads to the formation of layered cobalt hydroxynitrate compounds which have small crystalline size and have the role of a generator of hydroxyl anion. Structural and morphological characterizations were performed by using power X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), and high resolution transmission electron microscopy (HR-TEM). The component and thermal stability of the sample were respectively measured by Fourier transform infrared (FT-IR) spectroscopy, elemental analysis, and thermal analyses, including thermogravimetry (TG) and differential thermal analysis (DTA).

• The Journal of Korean Society for Radiation Therapy
• /
• v.10 no.1
• /
• pp.30-44
• /
• 1998

Accurate delivery of doses using a high dose rate(HDR) brachytherapy, remote afterloading system(RALS) depends on knowing the strength of the radioactive source at the time of treatment, the precision and consistency of the timer, and the ability of the unit to position the source at the proper dwell location along the applicator. Periodic Quality Assurance(QA) on HDR machines is a part of the standard protocol of any user. The safety of the patient & staff, positional accuracy, temporal accuracy, and dose delivery accuracy are periodically(weekly, quarterly, monthly) estimated using HDR source(Ir-192), treatment planning devices, measurement devices, and overall treatment devices with regard to treatment delivery. The overall measurement results are estimated successfully and assessed its clinical significance. As a result, our HDR brachytherapy units has been very accurate until now. The QA program protocol permits routine clinical use and provides a high confidence level in the accurate operation of HDR units. Therefore, regular QA of HDR brachytherapy is essential for successful treatment.

• Journal of the Korean Solar Energy Society
• /
• v.35 no.1
• /
• pp.21-28
• /
• 2015

A small washer powered directly and solely by thermal radiation was constructed and tested to explore the feasibility of using solar energy or other types of thermal radiation for washing and cleaning. In principle, TA (ThermoAcoustic) washers have the benefits of simpler design and operation and fewer energy conversion processes, thus should be more energy efficient and cost less than electric washing/cleaning systems. The prototype TA converter we constructed could sustain itself with consistent fluid oscillations for more than 20 minutes when powered by either concentrated solar radiation or an IR (infrared) heater. The frequencies of water oscillations in the wash chamber ranged from 2.6 to 3.6 Hz. The overall conversion efficiency was lower than the typical efficiencies of TA engines. Change in water temperature had little effect on the oscillatory flow in the TA washer due to its low efficiency. On the other hand higher water temperatures enhanced grease removal considerably in our tests. Methods for measuring the overall conversion efficiency, frictional loss, and grease removal of the TA washing system we designed were developed and discussed.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.39C no.12
• /
• pp.1307-1313
• /
• 2014

In this paper, we have proposed a tapered slot antenna for IR-UWB communication system suitable of indoor positioning in the building. The designed tapered slot antenna is designed using Ansys Inc. HFSS and its standing wave ratio, return loss, and radiation pattern is analyzed. In 2.36 GHz ~ 5.51 GHz and, the designed antenna shows satisfactory return loss at -10 dB and meets the requirement of $VSWR{\leq}2$. The presented designed showed a higher sensitivity for the end-fire propagation characteristics in a specific direction across all bands of the radiation pattern.