• 제목/요약/키워드: IPI

검색결과 61건 처리시간 0.025초

Proteomics Data Analysis using Representative Database

  • Kwon, Kyung-Hoon;Park, Gun-Wook;Kim, Jin-Young;Park, Young-Mok;Yoo, Jong-Shin
    • Bioinformatics and Biosystems
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    • 제2권2호
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    • pp.46-51
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    • 2007
  • In the proteomics research using mass spectrometry, the protein database search gives the protein information from the peptide sequences that show the best match with the tandem mass spectra. The protein sequence database has been a powerful knowledgebase for this protein identification. However, as we accumulate the protein sequence information in the database, the database size gets to be huge. Now it becomes hard to consider all the protein sequences in the database search because it consumes much computing time. For the high-throughput analysis of the proteome, usually we have used the non-redundant refined database such as IPI human database of European Bioinformatics Institute. While the non-redundant database can supply the search result in high speed, it misses the variation of the protein sequences. In this study, we have concerned the proteomics data in the point of protein similarities and used the network analysis tool to build a new analysis method. This method will be able to save the computing time for the database search and keep the sequence variation to catch the modified peptides.

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음절내 음소 출현 위치에 따른 한국어 양순 파열음의 공기역학적인 특징 (Aerodynamic Characteristics of Korean Bilabial Stop Consonant as a Function of Phonemic Position in a Syllable)

  • 박상희;정행임;정옥란;석동일
    • 음성과학
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    • 제9권4호
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    • pp.59-75
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    • 2002
  • Aerodynamic analysis study was performed on 14 normal subjects (2 males, 12 females) with nonsense syllables composed of Korean bilabial stops (/p, p', $p^{h}$) and their preceding and/or following vowels, /i, a, u/. That is, [pi, p'i, $p^{h}i$, pa, p'a, $p^{h}a$, pu, p'u, $p^{h}u$, ipi, apa, upu, $ip^{h}i$, $ap^{h}a$, $up^{h}u$, ip'i, ap'a, up'u]. All measures were taken and analysed using Aerophone II voice function analyzer and included peak air pressure, mean air pressure, maximum flow rate, volume, mean SPL and phonatory SPL. A t-test and one-way ANOVA were employed for analysis. A post-hoc analysis was performed with Scheffe and Bonferroni. The results were as follows: First, MSPL. and MAP of /p, p', $p^{h}$/ were significantly different in different positions (initial and medial position). In addition, different vowel environment also produced significantly different aerodynamic characteristics those consonants. Especially the lax consonant /p/ was significantly different /i, a, u/ vowel environments. The tense consonant /p'/ was significantly different only /i/ vowel environment.

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주파수 템플릿 정합법을 사용한 EMG 신호 분해 (The Decomposition of EMG signals using Template Matiching Method in the frequency domain)

  • 박세훈;이영우;고현운;예수영;엄상희;남기곤;전계록
    • 대한의용생체공학회:학술대회논문집
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    • 대한의용생체공학회 1997년도 추계학술대회
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    • pp.55-58
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    • 1997
  • In this paper, we study a signal processing method which extracts each MUAP(motor unit action potential) from EMG(Electromyogram) interference pattern or clinical diagnostic purposes. First of all, differential digital filtering is selected or eliminating the spike components of the MUAP's from the background noise. And, the algorithm identifies the spikes over the certanin threshold by template matching in frequency domain. After missing or false firing actor is cut off at the IPI(inter pulse interval) histogram, we averages the MUAP waveforms from the raw signal using the identified spikes as triggers, and Finally, measures their amplitudes, durations, and numbers of phases. Specially, We introduce algorithm performed by template matching in the frequency domain. A typical 3-s signal recorded from the biceps brachii muscle using a conventional needle electrode during a isometric contraction is used. Finally, the method decomposed five simultaneous active MUAP's from original EMG signal.

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홀로그래픽 데이터 저장장치를 위한 4레벨 6/9 변조부호 (4-level 6/9 Modulation Code for Holographic Data Storage)

  • 김병선;박근환;이재진
    • 한국통신학회논문지
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    • 제39A권10호
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    • pp.574-578
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    • 2014
  • 홀로그래픽 데이터 저장장치는 높은 저장용량, 빠른 전송 능력, 그리고 짧은 접근 시간 등의 장점을 가진다. 하지만 홀로그래픽 데이터 저장장치는 페이지 단위로 데이터를 처리하기 때문에 생기는 2차원 인접 심볼간 간섭과 하나의 체적에 여러 면의 페이지를 기록하여서 생기는 인접 페이지간 간섭의 심각한 성능 열화의 요소가 존재한다. 본 논문에서는 한 픽셀에 여러 레벨의 심볼을 저장하는 경우 발생할 수 있는 인접 심볼간 간섭을 줄이기 위한 4-레벨 6/9 변조부호를 제안한다.

US Purchasing Managers' Index and its Impact on Korea and US

  • Jeon, Ji-Hong
    • 유통과학연구
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    • 제15권3호
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    • pp.17-25
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    • 2017
  • Purpose - The study is to examine the impact of the US Purchasing Managers' Index (PMI) on Korea and the US industrial economy including the distribution industry. We analyze its effect on the industrial economy centered on the distribution industry using economy indices in Korea and the US. Research design, data, and methodology - The variables are used to analyze the dynamic relationship which occurs among the US PMI, the industrial production index, producer price index, unemployment rate, and manufacturing Inventories Index in Korea and the US from January 1990 to July 2016 using Vector Error Correction Model. Results - As a main result, the impact of the US PMI on all the economy indices both Korea and the US has the same cyclical movement. The US PMI is positively related to the producer price and the industrial production index of Korea and the US, while it is negatively related to unemployment rate, and the manufacturing inventories index in Korea and the US. Conclusions - The US PMI as an advanced index has a power to predict the economies on Korea and the US. In the end, we find that the US PMI has a great impact on Korea and the US industrial economy.

Two-Dimensional 8/9 Error Correcting Modulation Code

  • 이경오;김병선;이재진
    • 한국통신학회논문지
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    • 제39A권5호
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    • pp.215-219
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    • 2014
  • In holographic data storage (HDS), a high transmission rate is accomplished through the use of a charge coupled device array for reading two-dimensional (2D) pixel image data. Although HDS has many advantages in terms of storage capacity and data transmission rates, it also features problems, such as 2D intersymbol interference (ISI) by neighboring pixels and interpage interference (IPI) by multiple images stored in the same holographic volume. Modulation codes can be used to remove these problems. We introduce a 2D 8/9 error-correcting modulation code. The proposed modulation code exploits the trellis-coded modulation scheme, and the code rate is larger (about 0.889) than that of the conventional 6/8 balanced modulation code (an increase of approximately 13.9%). The performance of the bit error rate (BER) with the proposed scheme was improved compared with that of the 6/8 balanced modulation code and the simple 8/9 code without the trellis scheme.

보존 환경 평가 지수를 이용한 종이 보존 서고 환경 모니터링 연구 (Study on Environmental Monitoring in Stack Room for Paper Storage Using the Preservation Index)

  • 신현창;윤만영
    • 한국인쇄학회지
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    • 제29권1호
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    • pp.61-74
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    • 2011
  • Critical environmental elements for long term preservation of a paper are temperature, humidity, dust, light, contaminants in air, and mold. Especially, temperature and humidity need special care, because they can not only directly degrade paper but also affect the degradation of the other elements. Therefore methods to monitor variation of temperature and relative humidity were studied. One of the methods was to use preservation index for evaluating preservation environment. Since the evaluation for preservation environment of a stack room investigated firstly by D. K. Sebera, PI(preservation index) and TWPI(Time-Weighted Preservation Index) by IPI is made to evaluate relatively preservation environment in a stack room. T. Padfield developed method which could calculate easy PI and TWPI. In this study, the preservation environment of stack rooms for paper storage in NAK(National Archives Korea) was evaluated by PI and TWPI. PI and TWPI of stack rooms for paper storage in NAK maintained good condition but PI depended on season. Then the preservation environment of stack rooms for paper storage in NAK was required to maintain continuously PI and TWPI regardless of season change.

멀티코어 프로세서 기반 ARM TrustZone 환경에서의 게스트 운영체제 간 통신 (Inter-GuestOS Communications in Multicore-based ARM TrustZone)

  • 전무웅;김세원;유혁
    • 정보과학회 논문지
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    • 제42권5호
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    • pp.551-557
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    • 2015
  • ARM TrustZone을 이용한 기술은 새로운 임베디드 시스템의 가상화 연구로 관심을 끌고 있다. ARM TrustZone은 secure world와 normal world라는 두 개의 가상 실행 환경을 정의한다. 소프트웨어의 기능을 확장하기 위한 방법으로 ARM TrustZone 환경에서 world 간 통신은 중요하다. 그러나 현재의 모니터 모드의 소프트웨어는 world 간 통신을 충분히 지원하지 않고 있다. 본 논문에서는 ARM TrustZone을 이용한 각 world에서 구동되는 게스트 운영체제 간의 새로운 통신 메커니즘을 제시한다. 제안한 통신 메카니즘은 싱글코어와 멀티코어에서 양방향 world 간 통신을 지원한다. 본 논문에서는 ARM Cortex-A9 MPCore 기반의 NVIDIA Tegra3 processor를 사용하였고, 30MB/s이상의 통신 성능을 보여주었다.

Blockchain and Physically Unclonable Functions Based Mutual Authentication Protocol in Remote Surgery within Tactile Internet Environment

  • Hidar, Tarik;Abou el kalam, Anas;Benhadou, Siham;Kherchttou, Yassine
    • International Journal of Computer Science & Network Security
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    • 제22권9호
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    • pp.15-22
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    • 2022
  • The Tactile Internet technology is considered as the evolution of the internet of things. It will enable real time applications in all fields like remote surgery. It requires extra low latency which must not exceed 1ms, high availability, reliability and strong security system. Since it appearance in 2014, tremendous efforts have been made to ensure authentication between sensors, actuators and servers to secure many applications such as remote surgery. This human to machine relationship is very critical due to its dependence of the human live, the communication between the surgeon who performs the remote surgery and the robot arms, as a tactile internet actor, should be fully and end to end protected during the surgery. Thus, a secure mutual user authentication framework has to be implemented in order to ensure security without influencing latency. The existing methods of authentication require server to stock and exchange data between the tactile internet entities, which does not only make the proposed systems vulnerables to the SPOF (Single Point of Failure), but also impact negatively on the latency time. To address these issues, we propose a lightweight authentication protocol for remote surgery in a Tactile Internet environment, which is composed of a decentralized blockchain and physically unclonable functions. Finally, performances evaluation illustrate that our proposed solution ensures security, latency and reliability.

비호지킨림프종 환자의 발열성 호중구감소증에 대한 페그필그라스팀의 예방효과 (Prophylactic Effect of Pegfilgrastim on Febrile Neutropenia in Patients with Non-Hodgikin's Lymphoma)

  • 조주희;방준석
    • 한국임상약학회지
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    • 제25권2호
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    • pp.80-93
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    • 2015
  • Objective: Pegfilgrastim is recently introduced that is long acting G-CSF for prophylaxis of febrile neutropenia. Treatment of non-Hodgikin's lymphoma (NHL) with R-CHOP is classified with relative high risk of febrile neutropenia. The study evaluated the prophylactic effect of pegfilgrastim to reduce the incidence of febrile neutropenia associated with R-CHOP of patient in NHL. And the risk factors associated with the incidence of FN and related events were evaluated. Methods: This retrospective study reviews the Electronic Medical Record of 68 NHL patients who received R-CHOP chemotherapy in single center between September 2013 and August 2014. These patients were classified who receive prophylaxis pegfilgrastim or no prophylaxis. Results: Sixty eight patients received R-CHOP with NHL. In 144 cycles of patients receiving pegfilgrastim, compared with no prophylaxis 178 cycles, had a lower incidence of febrile neutropenia (5.5% vs. 23.6%, p = 0.001), grade 3 or grade 4 neutropenia (14.4% vs. 89.8%, p < 0.001) and neutropenia related events (p < 0.05). The risk of febrile neutropenia after prophylaxis was significantly associated with age ${\geq}65$ (OR: 5.87, 95% CI 1.07-32.27, p = 0.042), $IPI{\geq}3$ (OR: 7.2, 95% CI 1.31-39.6, p = 0.023), S.alb < 3.5 g/dL (OR: 31.01, 95% CI 6.32-152.17, p < 0.0001). In multiple logistic regression analysis, lower baseline serum albumin (OR: 21.1, 95% CI 3.8-116.98, p = 0.001) was significantly associated with occurrence of febrile neutropenia. Conclusion: The study recommends prophylactic pegfilgrastim through risk assessment of febrile neutropenia in patients with non-Hodgikin's lymphoma receiving R-CHOP.