• Title/Summary/Keyword: IPI

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Proteomics Data Analysis using Representative Database

  • Kwon, Kyung-Hoon;Park, Gun-Wook;Kim, Jin-Young;Park, Young-Mok;Yoo, Jong-Shin
    • Bioinformatics and Biosystems
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    • v.2 no.2
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    • pp.46-51
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    • 2007
  • In the proteomics research using mass spectrometry, the protein database search gives the protein information from the peptide sequences that show the best match with the tandem mass spectra. The protein sequence database has been a powerful knowledgebase for this protein identification. However, as we accumulate the protein sequence information in the database, the database size gets to be huge. Now it becomes hard to consider all the protein sequences in the database search because it consumes much computing time. For the high-throughput analysis of the proteome, usually we have used the non-redundant refined database such as IPI human database of European Bioinformatics Institute. While the non-redundant database can supply the search result in high speed, it misses the variation of the protein sequences. In this study, we have concerned the proteomics data in the point of protein similarities and used the network analysis tool to build a new analysis method. This method will be able to save the computing time for the database search and keep the sequence variation to catch the modified peptides.

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Aerodynamic Characteristics of Korean Bilabial Stop Consonant as a Function of Phonemic Position in a Syllable (음절내 음소 출현 위치에 따른 한국어 양순 파열음의 공기역학적인 특징)

  • Park, Sang-Hee;Jeong, Haeng-Im;Jeong, Ok-Ran;Seok, Dong-Il
    • Speech Sciences
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    • v.9 no.4
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    • pp.59-75
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    • 2002
  • Aerodynamic analysis study was performed on 14 normal subjects (2 males, 12 females) with nonsense syllables composed of Korean bilabial stops (/p, p', $p^{h}$) and their preceding and/or following vowels, /i, a, u/. That is, [pi, p'i, $p^{h}i$, pa, p'a, $p^{h}a$, pu, p'u, $p^{h}u$, ipi, apa, upu, $ip^{h}i$, $ap^{h}a$, $up^{h}u$, ip'i, ap'a, up'u]. All measures were taken and analysed using Aerophone II voice function analyzer and included peak air pressure, mean air pressure, maximum flow rate, volume, mean SPL and phonatory SPL. A t-test and one-way ANOVA were employed for analysis. A post-hoc analysis was performed with Scheffe and Bonferroni. The results were as follows: First, MSPL. and MAP of /p, p', $p^{h}$/ were significantly different in different positions (initial and medial position). In addition, different vowel environment also produced significantly different aerodynamic characteristics those consonants. Especially the lax consonant /p/ was significantly different /i, a, u/ vowel environments. The tense consonant /p'/ was significantly different only /i/ vowel environment.

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The Decomposition of EMG signals using Template Matiching Method in the frequency domain (주파수 템플릿 정합법을 사용한 EMG 신호 분해)

  • Park, S.H.;Lee, Y.W.;Go, H.W.;Ye, S.Y.;Eom, S.H.;Nam, K.G.;Jun, K.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1997 no.11
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    • pp.55-58
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    • 1997
  • In this paper, we study a signal processing method which extracts each MUAP(motor unit action potential) from EMG(Electromyogram) interference pattern or clinical diagnostic purposes. First of all, differential digital filtering is selected or eliminating the spike components of the MUAP's from the background noise. And, the algorithm identifies the spikes over the certanin threshold by template matching in frequency domain. After missing or false firing actor is cut off at the IPI(inter pulse interval) histogram, we averages the MUAP waveforms from the raw signal using the identified spikes as triggers, and Finally, measures their amplitudes, durations, and numbers of phases. Specially, We introduce algorithm performed by template matching in the frequency domain. A typical 3-s signal recorded from the biceps brachii muscle using a conventional needle electrode during a isometric contraction is used. Finally, the method decomposed five simultaneous active MUAP's from original EMG signal.

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4-level 6/9 Modulation Code for Holographic Data Storage (홀로그래픽 데이터 저장장치를 위한 4레벨 6/9 변조부호)

  • Kim, Byungsun;Park, Keunhwan;Lee, Jaejin
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39A no.10
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    • pp.574-578
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    • 2014
  • A holographic data storage (HDS) has some advantages of high storage capacity, fast transmission, and short access time. However, there are two major concerns with the system which are two-dimensional (2D) inter-symbol interference (ISI) and inter-page interference (IPI). Thus, this paper proposes a 4-level 6/9 modulation code which mitigate inter-symbol interference (ISI).

US Purchasing Managers' Index and its Impact on Korea and US

  • Jeon, Ji-Hong
    • Journal of Distribution Science
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    • v.15 no.3
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    • pp.17-25
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    • 2017
  • Purpose - The study is to examine the impact of the US Purchasing Managers' Index (PMI) on Korea and the US industrial economy including the distribution industry. We analyze its effect on the industrial economy centered on the distribution industry using economy indices in Korea and the US. Research design, data, and methodology - The variables are used to analyze the dynamic relationship which occurs among the US PMI, the industrial production index, producer price index, unemployment rate, and manufacturing Inventories Index in Korea and the US from January 1990 to July 2016 using Vector Error Correction Model. Results - As a main result, the impact of the US PMI on all the economy indices both Korea and the US has the same cyclical movement. The US PMI is positively related to the producer price and the industrial production index of Korea and the US, while it is negatively related to unemployment rate, and the manufacturing inventories index in Korea and the US. Conclusions - The US PMI as an advanced index has a power to predict the economies on Korea and the US. In the end, we find that the US PMI has a great impact on Korea and the US industrial economy.

Two-Dimensional 8/9 Error Correcting Modulation Code

  • Lee, Kyoungoh;Kim, Byungsun;Lee, Jaejin
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39A no.5
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    • pp.215-219
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    • 2014
  • In holographic data storage (HDS), a high transmission rate is accomplished through the use of a charge coupled device array for reading two-dimensional (2D) pixel image data. Although HDS has many advantages in terms of storage capacity and data transmission rates, it also features problems, such as 2D intersymbol interference (ISI) by neighboring pixels and interpage interference (IPI) by multiple images stored in the same holographic volume. Modulation codes can be used to remove these problems. We introduce a 2D 8/9 error-correcting modulation code. The proposed modulation code exploits the trellis-coded modulation scheme, and the code rate is larger (about 0.889) than that of the conventional 6/8 balanced modulation code (an increase of approximately 13.9%). The performance of the bit error rate (BER) with the proposed scheme was improved compared with that of the 6/8 balanced modulation code and the simple 8/9 code without the trellis scheme.

Study on Environmental Monitoring in Stack Room for Paper Storage Using the Preservation Index (보존 환경 평가 지수를 이용한 종이 보존 서고 환경 모니터링 연구)

  • Shin, Hyun-Chang;Yoon, Man-Young
    • Journal of the Korean Graphic Arts Communication Society
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    • v.29 no.1
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    • pp.61-74
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    • 2011
  • Critical environmental elements for long term preservation of a paper are temperature, humidity, dust, light, contaminants in air, and mold. Especially, temperature and humidity need special care, because they can not only directly degrade paper but also affect the degradation of the other elements. Therefore methods to monitor variation of temperature and relative humidity were studied. One of the methods was to use preservation index for evaluating preservation environment. Since the evaluation for preservation environment of a stack room investigated firstly by D. K. Sebera, PI(preservation index) and TWPI(Time-Weighted Preservation Index) by IPI is made to evaluate relatively preservation environment in a stack room. T. Padfield developed method which could calculate easy PI and TWPI. In this study, the preservation environment of stack rooms for paper storage in NAK(National Archives Korea) was evaluated by PI and TWPI. PI and TWPI of stack rooms for paper storage in NAK maintained good condition but PI depended on season. Then the preservation environment of stack rooms for paper storage in NAK was required to maintain continuously PI and TWPI regardless of season change.

Inter-GuestOS Communications in Multicore-based ARM TrustZone (멀티코어 프로세서 기반 ARM TrustZone 환경에서의 게스트 운영체제 간 통신)

  • Jeon, Moowoong;Kim, Sewon;Yoo, Hyuck
    • Journal of KIISE
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    • v.42 no.5
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    • pp.551-557
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    • 2015
  • The technology using ARM TrustZone draws attention as a new embedded virtualization approach. The ARM TrustZone defines two virtual execution environment, the secure world and the normal world. In such an environment, the inter-world communication is important to extend function of software. However, the current monitor software does not sufficiently support the inter-world communication. This paper presents a new inter guestOS communication scheme, for each world, for the ARM TrustZone virtualization. The proposed communication scheme supports bidirectional inter-world communication for single core and multicore environment. In this paper, It is implemented on a NVIDIA Tegra3 processor based on the ARM Cortex-A9 MPCore and it showed a bandwidth of 30MB/s.

Blockchain and Physically Unclonable Functions Based Mutual Authentication Protocol in Remote Surgery within Tactile Internet Environment

  • Hidar, Tarik;Abou el kalam, Anas;Benhadou, Siham;Kherchttou, Yassine
    • International Journal of Computer Science & Network Security
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    • v.22 no.9
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    • pp.15-22
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    • 2022
  • The Tactile Internet technology is considered as the evolution of the internet of things. It will enable real time applications in all fields like remote surgery. It requires extra low latency which must not exceed 1ms, high availability, reliability and strong security system. Since it appearance in 2014, tremendous efforts have been made to ensure authentication between sensors, actuators and servers to secure many applications such as remote surgery. This human to machine relationship is very critical due to its dependence of the human live, the communication between the surgeon who performs the remote surgery and the robot arms, as a tactile internet actor, should be fully and end to end protected during the surgery. Thus, a secure mutual user authentication framework has to be implemented in order to ensure security without influencing latency. The existing methods of authentication require server to stock and exchange data between the tactile internet entities, which does not only make the proposed systems vulnerables to the SPOF (Single Point of Failure), but also impact negatively on the latency time. To address these issues, we propose a lightweight authentication protocol for remote surgery in a Tactile Internet environment, which is composed of a decentralized blockchain and physically unclonable functions. Finally, performances evaluation illustrate that our proposed solution ensures security, latency and reliability.

Prophylactic Effect of Pegfilgrastim on Febrile Neutropenia in Patients with Non-Hodgikin's Lymphoma (비호지킨림프종 환자의 발열성 호중구감소증에 대한 페그필그라스팀의 예방효과)

  • Jo, Juhee;Bang, Joon Seok
    • Korean Journal of Clinical Pharmacy
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    • v.25 no.2
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    • pp.80-93
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    • 2015
  • Objective: Pegfilgrastim is recently introduced that is long acting G-CSF for prophylaxis of febrile neutropenia. Treatment of non-Hodgikin's lymphoma (NHL) with R-CHOP is classified with relative high risk of febrile neutropenia. The study evaluated the prophylactic effect of pegfilgrastim to reduce the incidence of febrile neutropenia associated with R-CHOP of patient in NHL. And the risk factors associated with the incidence of FN and related events were evaluated. Methods: This retrospective study reviews the Electronic Medical Record of 68 NHL patients who received R-CHOP chemotherapy in single center between September 2013 and August 2014. These patients were classified who receive prophylaxis pegfilgrastim or no prophylaxis. Results: Sixty eight patients received R-CHOP with NHL. In 144 cycles of patients receiving pegfilgrastim, compared with no prophylaxis 178 cycles, had a lower incidence of febrile neutropenia (5.5% vs. 23.6%, p = 0.001), grade 3 or grade 4 neutropenia (14.4% vs. 89.8%, p < 0.001) and neutropenia related events (p < 0.05). The risk of febrile neutropenia after prophylaxis was significantly associated with age ${\geq}65$ (OR: 5.87, 95% CI 1.07-32.27, p = 0.042), $IPI{\geq}3$ (OR: 7.2, 95% CI 1.31-39.6, p = 0.023), S.alb < 3.5 g/dL (OR: 31.01, 95% CI 6.32-152.17, p < 0.0001). In multiple logistic regression analysis, lower baseline serum albumin (OR: 21.1, 95% CI 3.8-116.98, p = 0.001) was significantly associated with occurrence of febrile neutropenia. Conclusion: The study recommends prophylactic pegfilgrastim through risk assessment of febrile neutropenia in patients with non-Hodgikin's lymphoma receiving R-CHOP.