• 한국통신학회논문지
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• 제41권8호
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• pp.974-985
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• 2016

Riverbed Modeler는 복잡한 통신 프로토콜과 큰 규모의 네트워크를 설계하기 위한 패킷 수준의 이산 사건 시뮬레이터이며 그 신뢰성을 인정받아 대규모 네트워크의 성능분석에 널리 활용되고 있다. Riverbed Modeler를 활용하는 MANET 시뮬레이션 환경에서, 새로운 라우팅 프로토콜을 구현하여 추가하는 방법이 매우 복잡하고 많은 부분의 수정을 요구한다. 본 논문에서는 Riverbed Modeler의 라우팅 지원 구조에 대하여 살펴보고, 라우팅 추가에 대한 어려움을 해결하기 위하여 보다 쉽고 실수의 가능성을 줄일 수 있는 라우팅 추가 프레임워크를 제안하였다. 라우팅 추가 프레임워크는 프로토콜을 인식하는 부분에 대하여 적응적 구조 갖는 API로서 제공되며, 라우팅 프로토콜을 최소한의 수정으로 추가할 수 있도록 구성하였다. 라우팅 추가 프레임워크를 이용하여 라우팅 프로토콜을 추가하는 경우, 수정해야 하는 부분을 기존의 절반 이하로 간소화 하였다. 또한 제안한 라우팅 추가 프레임워크를 이용하여 Hybrid 라우팅 프로토콜인 AntHocNet을 구현하여 추가한 사례를 제시하여, 라우팅 추가 프레임워크가 타당하게 설계 및 적용되었음을 확인하였다.

• BMB Reports
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• 제43권7호
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• pp.485-490
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• 2010

Neurotrophins regulate many aspects of neuronal function through activation of the high affinity Trk receptors. Shc family proteins are implicated in the coupling of RTK to the Ras/mitogen-activated protein kinase signaling cascade. Here we report that the fourth Shc family member, ShcD, associates with TrkB receptor and regulates BDNF-induced MAPK activation. Yeast two-hybrid assay and Co-IP experiments demonstrate ShcD interacts with TrkB in a kinase-activity-dependent manner. Confocal analysis shows ShcD cololizes well with TrkB in transfected 293T cells. Subsequent mapping experiments and mutational analysis indicate that both PTB and SH2 domains are capable of binding to TrkB and PTB domain binds to TrkB NPQY motif. Furthermore, ShcD is involved in BDNF-induced MAPK activation. In summary, we demonstrate that ShcD is a substrate of TrkB and mediates TrkB downstream signaling pathway.

• 한국동물번식학회:학술대회논문집
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• 한국동물번식학회 2003년도 학술발표대회 발표논문초록집
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• pp.80-80
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• 2003

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder characterized by motor, cognitive, and psychiatric symptoms, accompanied by marked cell death in the striatum and cortex. Stereotaxic injection of quinolinic acid (QA) into striatum results in a degeneration of GABAergic neurons and exhibits abnormal motor behaviors typical of the illness. The objective of this study was carried out to obtain basic information about whether parthenogenetic mouse embryonic stem (PmES) cells are suitable for cell replacement therapy of HD. To establish PmES cell lines, hybrid F1 (C57BL/6xCBA/N) mouse oocytes were treated with 7% ethanol for 5 min and cytochalasin-B for 4 hr to initiate spontaneous cleavage. Thus established PmES cells were induced to differentiate using bFGF (20ng/ml) followed by selection of neuronal precursor cells for 8 days in N2 medium. After selection, cells were expanded at the presence of bFGF (20 ng/ml) for another 6 days, then a final differentiation step in N2 medium for 7 days. To establish recipient animal models of HD, young adult mice (7 weeks age ICR mice) were lesioned unilaterally with a stereotaxic injection of QA (60 nM) into the striatum and the rotational behavior of the animals was tested using apomorphine (0.1mg/kg, IP) 7 days after the induction of lesion. Animals rotating more than 120 turns per hour were selected and the differentiated PmES cells (1$\times$10$^4$cells/ul) were implanted into striatum. Four weeks after the graft, immunohistochemical studies revealed the presence of cells reactive to anti-NeuN antibody. However, only a slight improvement of motor behavior was observed. By Nissl staining, cell mass resembling tumor was found at the graft site and near cortex which may explain the slight behavioral improvement. Detailed experiment on cell viability, differentiation and migration explanted in vivo is currently being studied.

• Journal of Communications and Networks
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• 제6권3호
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• pp.269-279
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• 2004

A new online multi-layer integrated routing (MLIR) scheme that combines IP (electrical) layer routing with WDM (optical) layer routing is investigated. It is a highly efficient and cost-effective routing scheme viable for the next generation integrated optical Internet. A new simplified weighted graph model for the integrated optical Internet consisted of optical routers with multi-granularity optical-electrical hybrid switching capability is firstly proposed. Then, based on the proposed graph model, we develop an online integrated routing scheme called differentiated weighted fair algorithm (DWFA) employing adaptive admission control (routing) strategies with the motivation of service/bandwidth differentiation, which can jointly solve multi-layer routing problem by simply applying the minimal weighted path computation algorithm. The major objective of DWFA is fourfold: 1) Quality of service (QoS) routing for traffic requests with various priorities; 2) blocking fairness for traffic requests with various bandwidth granularities; 3) adaptive routing according to the policy parameters from service provider; 4) lower computational complexity. Simulation results show that DWFA performs better than traditional overlay routing schemes such as optical-first-routing (OFR) and electrical-first-routing (EFR), in terms of traffic blocking ratio, traffic blocking fairness, average traffic logical hop counts, and global network resource utilization. It has been proved that the DWFA is a simple, comprehensive, and practical scheme of integrated routing in optical Internet for service providers.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2000년도 제15차 학술회의논문집
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• pp.103-103
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• 2000

In this paper to cope with the reduction of products life-cycle as the variety of products along with the various demands of consumers, a virtual simulator is developed to make the changeover of manufacturing line efficient to embody a virtual simulation similar to a real manufacturing line. The developed virtual simulator can design a layout of a factory and make the time scheduling. Every factory has one simulator so that one product can be manufactured in the factories to use them as virtual factories. We suggest a scheme that heightens the agility to the diversity of manufacturing models by making the information of manufacturing lines and products models to be shared. The developed unit simulator can construct a proper virtual manufacturing line along with the required process of products using several kinds of operator and work cell. A user with the simulator can utilize an interface that makes one to manage the separate task process for each manu(acturing module, change operator components and work cells, and easily teach tasks of each task module. The developed simulator was made for users convenience by Microsoft Visual C++ 6.0 that can develop a program supplying graphic user interface environment and by OpenGL of the Silicon Graphics as a graphic library to embody 3D graphic environment. Also, we show that the simulator can be used efficiently for the agile manufacturing by the communication among the factories being linked by TCP/IP and a hybrid database system made by a hierarchical model and a relational model being developed to standardize the data information.

• 한국정보통신학회논문지
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• 제10권2호
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• pp.328-332
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• 2006

정보 보호 응용에 새로운 이슈가 되고 있는 ECC 공개키 암호 알고리즘은 유한체 차원에서의 효율적인 연산처리가 중요하다. 직렬 유한체 곱셈기의 근간은 Mastrovito의 직렬 곱셈기에서 유래한다. 본 논문에서는 polynomial basis 방식을 적용하고 식을 유도하여 Mastrovito의 직렬 유한체 곱셈방식의 3배 성능을 보이는 유한체 곱셈기를 제안하고, HDL로 기술하여 기능을 검증하고 성능을 평가한다. 설계된 3배속 직렬 유한체 곱셈기는 부분합을 생성하는 회로의 추가만으로 기존 직렬 곱셈기의 3배의 성능을 보여주었다. 비도 높은 암호용으로 연구된 유한체 곱셈 연산기는 크게 직렬 유한체 곱셈기, 배열 유한체 곱셈기, 하이브리드 유한체 곱셈기으로 분류되어 왔다. 본 논문에서는 Mastrovito의 곱셈기의 구조를 기본으로 하고, 수식적으로 공통인수를 끌어내어 후처리하는 기법을 유도하여 적용한다. 제안한 방식으로 설계한 새로운 유한체 곱셈기는 HDL로 구현하여 소프트웨어 측면 뿐 아니라 하드웨어 측면에서도 그 기능과 성능을 검증하였다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제13권6호
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• pp.2964-2985
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• 2019

Global data center IP traffic is expected to reach 20.6 zettabytes (ZB) by the end of 2021. Intra-data center networks (Intra-DCN) will account for 71.5% of the data center traffic flow and will be the largest portion of the traffic. The understanding of traffic distribution in IntraDCN is still sketchy. It causes significant amount of bandwidth to go unutilized, and creates avoidable choke points. Conventional transport protocols such as Optical Packet Switching (OPS) and Optical Burst Switching (OBS) allow a one-sided view of the traffic flow in the network. This therefore causes disjointed and uncoordinated decision-making at each node. For effective resource planning, there is the need to consider joining the distributed with centralized management which anticipates the system's needs and regulates the entire network. Methods derived from Kalman filters have proved effective in planning road networks. Considering the network available bandwidth as data transport highways, we propose an intelligent enhanced SDN concept applied to OBS architecture. A management plane (MP) is added to conventional control (CP) and data planes (DP). The MP assembles the traffic spatio-temporal parameters from ingress nodes, uses Kalman filtering prediction-based algorithm to estimate traffic demand. Prior to packets arrival at edges nodes, it regularly forwards updates of resources allocation to CPs. Simulations were done on a hybrid scheme (1+1) and on the centralized OBS. The results demonstrated that the proposition decreases the packet loss ratio. It also improves network latency and throughput-up to 84 and 51%, respectively, versus the traditional scheme.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권11호
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• pp.3991-4010
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• 2021

The Question Similarity Measurement of Chinese Crop Diseases and Insect Pests (QSM-CCD&IP) aims to judge the user's tendency to ask questions regarding input problems. The measurement is the basis of the Agricultural Knowledge Question and Answering (Q & A) system, information retrieval, and other tasks. However, the corpus and measurement methods available in this field have some deficiencies. In addition, error propagation may occur when the word boundary features and local context information are ignored when the general method embeds sentences. Hence, these factors make the task challenging. To solve the above problems and tackle the Question Similarity Measurement task in this work, a corpus on Chinese crop diseases and insect pests(CCDIP), which contains 13 categories, was established. Then, taking the CCDIP as the research object, this study proposes a Chinese agricultural text similarity matching model, namely, the AgrCQS. This model is based on mixed information extraction. Specifically, the hybrid embedding layer can enrich character information and improve the recognition ability of the model on the word boundary. The multi-scale local information can be extracted by multi-core convolutional neural network based on multi-weight (MM-CNN). The self-attention mechanism can enhance the fusion ability of the model on global information. In this research, the performance of the AgrCQS on the CCDIP is verified, and three benchmark datasets, namely, AFQMC, LCQMC, and BQ, are used. The accuracy rates are 93.92%, 74.42%, 86.35%, and 83.05%, respectively, which are higher than that of baseline systems without using any external knowledge. Additionally, the proposed method module can be extracted separately and applied to other models, thus providing reference for related research.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2022년도 학술발표회
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• pp.334-334
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• 2022

Improvement of old-fashioned rain gauge systems for automatic, timely, continuous, and accurate precipitation observation is highly essential for weather/climate prediction and natural hazards early warning, since the occurrence frequency and intensity of heavy and extreme precipitation events (especially floods) are recently getting more increase and severe worldwide due to climate change. Although rain gauge accuracy of 0.1 mm is recommended by the World Meteorological Organization (WMO), the traditional rain gauges in both weighting and tipping bucket types are often unable to meet that demand due to several existing technical limitations together with higher production and maintenance costs. Therefore, we aim to introduce a newly developed and cost-effective hybrid rain gauge system at 0.1 mm accuracy that combines advantages of weighting and tipping bucket types for continuous, automatic, and accurate precipitation observation, where the errors from long-term load cells and external environmental sources (e.g., winds) can be removed via an automatic drainage system and artificial intelligence-based data quality control procedure. Our rain gauge system consists of an instrument unit for measuring precipitation, a communication unit for transmitting and receiving measured precipitation signals, and a database unit for storing, processing, and analyzing precipitation data. This newly developed rain gauge was designed according to the weather instrument criteria, where precipitation amounts filled into the tipping bucket are measured considering the receiver's diameter, the maximum measurement of precipitation, drainage time, and the conductivity marking. Moreover, it is also designed to transmit the measured precipitation data stored in the PCB through RS232, RS485, and TCP/IP, together with connecting to the data logger to enable data collection and analysis based on user needs. Preliminary results from a comparison with an existing 1.0-mm tipping bucket rain gauge indicated that our developed rain gauge has an excellent performance in continuous precipitation observation with higher measurement accuracy, more correct precipitation days observed (120 days), and a lower error of roughly 27 mm occurred during the measurement period.

• BMB Reports
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• 제41권4호
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• pp.287-293
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• 2008

In a yeast two-hybrid screen, we identified the microtubule-destabilizing protein SCG10 as a potential effector protein of $BRI_3$. The association was verified using GST pull-down, Co-IP, and their perinuclear co-localization. The analysis of in vitro microtubule polymerization/depolymerization showed that the binding of $BRI_3$ to SCG10 effectively blocked the ability of SCG10 to induce microtubule disassembly, as determined by turbidimetric assays. In intact PC12 cells, $BRI_3$ exhibited the ability to stabilize the microtubule network and attenuate the microtubule-destabilizing activity of SCG10. Furthermore, co-expression of $BRI_3$ with SCG10 attenuated SCG10-mediated PC12 cell neurite outgrowth induced by NGF. These results identify a novel connection between a neuron-specific BRI protein and the cytoskeletal network, suggesting possible roles of BRI3 in the process of neuronal differentiation.