• Title/Summary/Keyword: INTERMEDIATE FORM

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Synthesis of Dienamides via the Reaction of Nitrile with Allylindium Reagents and Intramolecular Acyl Group Quenching Cascade

  • Kim, Sung-Hwan;Kim, Yu-Mi;Kim, Jae-Nyoung
    • Bulletin of the Korean Chemical Society
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    • v.31 no.8
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    • pp.2351-2356
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    • 2010
  • Various dienamide derivatives were synthesized in reasonable yields from benzonitriles having an amide moiety at the ortho-position, via the sequential (i) In-mediated allylation of nitrile moiety to form an imine intermediate, (ii) intramolecular quenching of an acyl group by the imine intermediate, and (iii) a proton transfer to dienamide.

A Study on Possible Interaction between Nicotine-specific Nitrosamines and Nucleic Acid Bases by Molecular Orbital Theory (I) N'-nitrosonornicotine and Its Metabolic Intermediates (분자궤도 함수이론에 의한 니코틴 특이 니트로사민과 핵산염기와의 가능한 상호작용에 관한 연구(I) 니트로소놀니코틴과 그 대사중간물질)

  • 이종달
    • YAKHAK HOEJI
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    • v.26 no.3
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    • pp.175-180
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    • 1982
  • The intermediate of N'-nitrosonornicotine may bind to the guanine moiety of a G-C base pair. The hydrogen bond of the base pair may be broken and a new hydrogen bond can form between the intermediate and the guanine. It results in the "short" type of DNA repair.NA repair.

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The intermediate solution of quasilinear elliptic boundary value problems

  • Ko, Bong-Soo
    • Journal of the Korean Mathematical Society
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    • v.31 no.3
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    • pp.401-416
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    • 1994
  • We study the existence of an intermediate solution of nonlinear elliptic boundary value problems (BVP) of the form $$ (BVP) {\Delta u = f(x,u,\Delta u), in \Omega {Bu(x) = \phi(x), on \partial\Omega, $$ where $\Omega$ is a smooth bounded domain in $R^n, n \geq 1, and \partial\Omega \in C^{2,\alpha}, (0 < \alpha < 1), \Delta$ is the Laplacian operator, $\nabla u = (D_1u, D_2u, \cdots, D_nu)$ denotes the gradient of u and $$ Bu(x) = p(x)u(x) + q(x)\frac{d\nu}{du} (x), $$ where $\frac{d\nu}{du} denotes the outward normal derivative of u on $\partial\Omega$.

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Mechanism of Peroxide-supported Hydroxylation by Cytochrome P-450 : Its Formation Pattern of the Active Intermediate (Hydroperoxide 의존성 반응에서의 Cytochrome P-450의 산화활성종 형성양식)

  • 문전옥;김기헌
    • YAKHAK HOEJI
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    • v.37 no.1
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    • pp.95-99
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    • 1993
  • Peroxidase activity of cytochrome P-450 was examined using N, N-dimethylaniline (NDA) as a substrate and cumene hydroperoxide (CHP) as an oxidant. The initial rates of the N-demethylation for varied concentrations of NDA (0.05-0.5 mM) by P-450 at different fixed concentrations of CHP (0.02-0.2 mM) were determined. The results suggest that P-450 proceeds its peroxidative reaction by the rapid equilibrium random bi bi mechanism to form a ternary complex with substrate and oxidant as an active intermediate.

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Component-Based VHDL Analyzer for Reuse and Embedment (재사용 및 내장 가능한 구성요소 기반 VHDL 분석기)

  • 박상헌;손영석
    • Proceedings of the IEEK Conference
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    • 2003.07b
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    • pp.1015-1018
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    • 2003
  • As increasing the size and complexity of hard-ware and software system, more efficient design methodology has been developed. Especially design-reuse technique enables fast system development via integrating existing hardware and software. For this technique available hardware/software should be prepared as component-based parts, adaptable to various systems. This paper introduces a component-based VHDL analyzer allowing to be embedded in other applications, such as simulator, synthesis tool, or smart editor. VHDL analyzer parses VHDL description input, and performs lexical, syntactic, semantic checking, and finally generates intermediate-form data as the result. VHDL has full-features of object-oriented language such as data abstraction, inheritance, and polymorphism. To support these features special analysis algorithm and intermediate form is required. This paper summarizes practical issues on implementing high-performance/quality VHDL analyzer and provides its solution that is based on the intensive experience of VHDL analyzer development.

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Modeling the human memory in nerve fields

  • Fujita, Osamu;Kakazu, Yukinori
    • 제어로봇시스템학회:학술대회논문집
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    • 1992.10b
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    • pp.70-73
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    • 1992
  • This paper describes the modeling of human memory using a nerve field model which is proposed for modeling the mechanism of brain mathematically. In our model, two phases of memory, retention and recollection, are focused on. The former consists of two stages, short-term memory (STM) and long-term memory (LTM). The proposed model consists of three parts, the STM Layer, LTM Layer and the Intermediate Layer between them. Each of these is constructed by a nerve field. In the STM Layer, memorized information is retained dynamically in the form of the reverberating states of units within the layer, while in the LTM Layer, it is stored statically in the form of structures of the weight on the links between units. the Intermediate Layer is introduced to translate this dynamic representation in the STM Layer to the LTNI Layer, and also to extract the static information from the STM Layer. In addition to this, we consider the recollection of information stored in the LTM. Finally, the behavior of this model is demonstrated by computer simulation.

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The Development of the User Interface Tool for DSP Silicon Compiler (디지틀 신호처리용 실리콘 컴파일러를 위한 사용자 툴 개발)

  • 이문기;장호랑;김종현;이승호;이광엽
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.29A no.9
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    • pp.76-84
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    • 1992
  • The DSP silicon compiler consists of language compiler, module generator, placement tool, router, layout generation tools, and simulator. In this paper, The language compiler, the module generator, placement tool, and simulator were developed and provided for the system designer. The language compiler translates the designer's system description language into the intermediate form file. The intermediate form file expresses the interconnections and specifications of the cells in the cell library. The simulator was developed and provided for the behavioral verification of the DSP system. For its implementation, the event-driven technique and the C$^{++}$ task library was used. The module generator was developed for the layout of the verified DSP system, and generates the functional block to be used in the DSP chip. And then the placement tool determines the appropriate positions of the cells in the DSP chip. In this paper, the placement tool was implemented by Min-Cut and Simulated Annealing algorithm. The placement process can be controlled by the several conditions input by the system designer.

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A Closed-Form Solution for Circular Openings in an Elastic-Brittle-Plastic Extended Spatial Mobilized Plane Medium

  • Wu, Chuangzhou;Guo, Wei;Jang, Bo-An
    • The Journal of Engineering Geology
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    • v.32 no.1
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    • pp.1-12
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    • 2022
  • Based on the extended spatial mobilization plane (SMP) criterion, we present an elastic-brittle-plastic solution for an axisymmetric cylindrical tunnel. The influences of the intermediate principal compressive stress and material strain-softening behavior are considered. Closed-form formulas for the critical support force, radius of plastic zone, and distributions of stress and displacement in surrounding rock are proposed. The elastic-plastic solution based on SMP is compared with the Kastner solution to verify the credibility of the obtained elastic-plastic solution. The elastic-brittle-plastic solution following the SMP criterion and the current solution based on the Mohr-Coulomb criterion are also compared. The rock strain-softening rate and the intermediate principal stress affect the stability of the surrounding rock. The results provide guidance for optimizing the design of support systems for tunnels.

Growth and Survival of the Spat of Arkshell, Scapharca broughtonii in Intermediate Culture with Different Shape of Protective Net and Type of Preventive Net of Spat Loss (피조개, Scaphara broughtonii 부착치패의 중간양성시 보호망 형태와 유실방지망 종류에 따른 성장과 생존)

  • Kim, Byeong-Hak;Shin, Yun-Kyung;Park, Ki-Yeol;Choi, Nack-Joong;Oh, Bong-Se;Min, Byeong-Hee
    • The Korean Journal of Malacology
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    • v.24 no.2
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    • pp.131-136
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    • 2008
  • Growth and survival of the spat of arkshell, Scapharca broughtonii were investigated for the improvement of survival in intermediate culture with different shape of protective net and type of preventive net of spat loss. The growth performance of the spat of arkshell was observed for 60 days by using different forms of protective net, as the exposure form with an average shell length of $12.8{\pm}3.2$ mm(P<0.05), the fish pot form with $12.2{\pm}3.5$ mm, the cylinder form with $11.9{\pm}3.8$ mm and the last one is the rectangular form with $10.9{\pm}3.7$ mm. Their numerical value did not show any marked difference with each other. But in case of survival rate, the fish pot form showed highest survival rate which is 43.7% and the significantly lowest was showed by the exposure form, which is 5.4%(P<0.05). The cylinder form and rectangular form showed 41.2 and 31.6% respectively. And then the growth of the spat of arkshell was observed for 163 days by rearing in a sort of preventive net, the first group was in a blackout curtain with average shell length of $13.9{\pm}3.1$ mm, the next group was in a balsam pear net with $12.9{\pm}3.0$ mm, in a polyethylene net with $11.8{\pm}3.1$ mm and the control with $12.6{\pm}3.3$ mm which was not installed by preventive net of spat loss. The survival rate was 91.5% in a blackout curtain, 90.1% in a polyethylene net, 88.5% in a balsam pear net and 61.5% in a controlled group. It is seen that the highest growth and survival rate were observed in a fish pot form and cylinder form. These results were a little bit difference from those of the spat of arkshell cultured in the form of different preventive nets. There was no significant difference in survival rate in relation to the sorts of preventive net against carrying-away, but there was a difference in survival rate by more than 30% as against the non-installed controlled group. We expect that survival rate would be highly improved in intermediate culture carried out with fish pot form and cylinder form of protective net and preventive net of spat loss.

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Development of Free-form PALs for Correcting Wavefront Refraction (파면굴절력 교정을 위한 자유형상 누진가입도렌즈 개발)

  • Baarg, Saang-Bai;Jeong, Mee-Suk
    • Journal of the Korean Society for Precision Engineering
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    • v.27 no.2
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    • pp.50-59
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    • 2010
  • In this paper, two kind of free-form progressive addition lenses (PALs) were designed with Zernike polynomial surface and anatomically accurate finite presbyopic schematic eyes which have aspheric cornea, aspheric GRIN crystalline lens, aspheric retina, and Gaussian apodization factor. Geometrical and diffraction MTFs were used for the optimization process in sequence. 5th orders of Zernike polynomials were used for the evaluation of progression zones of the two examples. The target MTF was set as 0.22 at 100 lp/mm which satisfies the standard visual resolution. These examples were fabricated with a CNC diamond turning machine controlled by slow tool servo (STS). After polishing process, the wavefront aberrations were measured with a laser interferometer on the ten test points across the progression zones and then compared with three current commercially available PALs on the optical performance. Astigmatic aberrations of the examples are very lower than the three selected PALs and have more increased stabilized progressive intermediate zones and near zones. It is expected to give better clear and comfortable distance, intermediate and near visions than other conventional PALs and to improve the adaptability of presbyopic patients to PALs.