• Title/Summary/Keyword: ILC

Search Result 89, Processing Time 0.024 seconds

Preoperative Magnetic Resonance Imaging Features Associated with Positive Resection Margins in Patients with Invasive Lobular Carcinoma

  • Jiyoung Yoon;Eun-Kyung Kim;Min Jung Kim;Hee Jung Moon;Jung Hyun Yoon;Vivian Y. Park
    • Korean Journal of Radiology
    • /
    • v.21 no.8
    • /
    • pp.946-954
    • /
    • 2020
  • Objective: To investigate preoperative magnetic resonance imaging (MRI) findings associated with resection margin status in patients with invasive lobular carcinoma (ILC) who underwent breast-conserving surgery. Materials and Methods: One hundred and one patients with ILC who underwent preoperative MRI were included. MRI (tumor size, multifocality, type of enhancing lesion, distribution of non-mass enhancement [NME], and degree of background parenchymal enhancement) and clinicopathological features (age, pathologic tumor size, presence of ductal carcinoma in situ [DCIS] or lobular carcinoma in situ, presence of lymph node metastases, and estrogen receptor/progesterone receptor/human epidermal growth factor receptor type 2 status) were analyzed. A positive resection margin was defined as the presence of invasive cancer or DCIS at the inked surface. Logistic regression analysis was performed to determine pre- and postoperative variables associated with positive resection margins. Results: Among the 101 patients, 21 (20.8%) showed positive resection margins. In the univariable analysis, NME, multifocality, axillary lymph node metastasis, and pathologic tumor size were associated with positive resection margins. With respect to preoperative MRI findings, multifocality (odds ratio [OR] = 3.977, p = 0.009) and NME (OR = 2.741, p = 0.063) were associated with positive resection margins in the multivariable analysis, although NME showed borderline significance. Conclusion: In patients with ILC, multifocality and the presence of NME on preoperative breast MRI were associated with positive resection margins.

Adaptive Learning Control fo rUnknown Monlinear Systems by Combining Neuro Control and Iterative Learning Control (뉴로제어 및 반복학습제어 기법을 결합한 미지 비선형시스템의 적응학습제어)

  • 최진영;박현주
    • Journal of the Korean Institute of Intelligent Systems
    • /
    • v.8 no.3
    • /
    • pp.9-15
    • /
    • 1998
  • This paper presents an adaptive learning control method for unknown nonlinear systems by combining neuro control and iterative learning control techniques. In the present control system, an iterative learning controller (ILC) is used for a process of short term memory involved in a temporary adaptive and learning manipulation and a short term storage of a specific temporary action. The learning gain of the iterative learning law is estimated by using a neural network for an unknown system except relative degrees. The control informations obtained by ILC are transferred to a long term memory-based feedforward neuro controller (FNC) and accumulated in it in addition to the previously stored infonnations. This scheme is applied to a two link robot manipulator through simulations.

  • PDF

A Study on Manufacturing of the Long Fiber-reinforced Thermoplastic (LFT) Automotive Under Cover Using the In-line Compounding (ILC) Technology (인라인 컴파운딩 기술을 이용한 장섬유강화 플라스틱 자동차 언더커버의 제조에 관한 연구)

  • Lee, Kyu-Se;Lee, Kyung-Sick
    • Composites Research
    • /
    • v.30 no.6
    • /
    • pp.399-405
    • /
    • 2017
  • We manufactured the long fiber-reinforced thermoplastic prototype of under cover using in-line compounding technology, and investigated the formability, mechanical properties and durability of the prototype of under cover. We manufactured the injection mold for the prototype through injection molding analysis and consideration of weight reduction. We investigated the formability of the prototype by evaluating the residual length and dispersion of fiber, and also tested the mechanical properties such as flexural strength, stiffness and impact strength. We investigated the durability of the prototype by the Key-Life Test(KLT) method which is generally used for the automotive interior parts.

Replication of Automotive Vibration Target Signal Using Iterative Learning Control and Stewart Platform with Halbach Magnet Array (반복학습제어와 할바흐 자석 배열 스튜어트 플랫폼을 이용한 차량 진동 신호 재현)

  • Ko, Byeongsik;Kang, SooYoung
    • Transactions of the Korean Society for Noise and Vibration Engineering
    • /
    • v.23 no.5
    • /
    • pp.438-444
    • /
    • 2013
  • This paper presents the replication of a desired vibration response by iterative learning control (ILC) system for a vibration motion replication actuator. The vibration motion replication actuator has parameter uncertainties including system nonlinearity and joint nonlinearity. Vehicle manufacturers worldwide are increasingly relying on road simulation facilities that put simulated loads and stresses on vehicles and subassemblies in order to reduce development time. Road simulation algorithm is the key point of developing road simulation system. With the rapid progress of digital signal processing technology, more complex control algorithms including iterative learning control can be utilized. In this paper, ILC algorithm was utilized to produce simultaneously the six channels of desired responses using the Stewart platform composed of six linear electro-magnetic actuators with Halbach magnet array. The convergence rate and accuracy showed reasonable results to meet the requirement. It shows that the algorithm is acceptable to replicate multi-channel vibration responses.

A Study on the Legal Control of Aircraft Terrorism by International Criminal Court(A Suggestion for the Amendment of ICC Statute) (국제형사재판소(國際刑事載判所)통한 항공기(航空機)테러범죄 규제에 관한 연구- ICC규정(規程)개정 위한 입법론적 고찰을 중심으로 -)

  • Kim, Man-Ho
    • The Korean Journal of Air & Space Law and Policy
    • /
    • v.15
    • /
    • pp.40-66
    • /
    • 2002
  • The purpose of this paper is to investigate the legal controㅣ, by using the International Criminal Court(ICC) that will enter into force to the most serious crimes of concern to the international community as a whole, and regulates the jurisdiction with respect to the following crimes: (a) The crime of genocide; (b) Crimes against humanity; (c) War crimes; Cd) The crime of aggression. However, the existing ICC Statute excludes (e) Crimes, established under or pursuant to the treaty, which was regulated by the ICC draft statute that the International Law Commission(ILC) examined and submitted to the UN General Assembly in 1994, and which contained aircraft terrorism such as hijacking in the Hague Convention of 1970 or sabotage in the Montreal Convention of 1971 in Annex of ILC draft. Therefore, this paper examines the legal character of aircraft terrorism as one of the most serious crimes of concern to the international community as a whole, and suggests two kinds of legislative comments for the amendment of the ICC Statute including aircraft terrorism as an object of the jurisdiction of the Court, for suppressing aircraft terrorism in advance and ensuring equitable penalty by ICC system.

  • PDF

Feedback-Based Iterative Learning Control for MIMO LTI Systems

  • Doh, Tae-Yong;Ryoo, Jung-Rae
    • International Journal of Control, Automation, and Systems
    • /
    • v.6 no.2
    • /
    • pp.269-277
    • /
    • 2008
  • This paper proposes a necessary and sufficient condition of convergence in the $L_2$-norm sense for a feedback-based iterative learning control (ILC) system including a multi-input multi-output (MIMO) linear time-invariant (LTI) plant. It is shown that the convergence conditions for a nominal plant and an uncertain plant are equal to the nominal performance condition and the robust performance condition in the feedback control theory, respectively. Moreover, no additional effort is required to design an iterative learning controller because the performance weighting matrix is used as an iterative learning controller. By proving that the least upper bound of the $L_2$-norm of the remaining tracking error is less than that of the initial tracking error, this paper shows that the iterative learning controller combined with the feedback controller is more effective to reduce the tracking error than only the feedback controller. The validity of the proposed method is verified through computer simulations.

Regulation of IgE-Mediated Food Allergy by IL-9 Producing Mucosal Mast Cells and Type 2 Innate Lymphoid Cells

  • Jee-Boong Lee
    • IMMUNE NETWORK
    • /
    • v.16 no.4
    • /
    • pp.211-218
    • /
    • 2016
  • Due to the increasing prevalence and number of life-threatening cases, food allergy has emerged as a major health concern. The classic immune response seen during food allergy is allergen-specific IgE sensitization and hypersensitivity reactions to foods occur in the effector phase with often severe and deleterious outcomes. Recent research has advanced understanding of the immunological mechanisms occurring during the effector phase of allergic reactions to ingested food. Therefore, this review will not only cover the mucosal immune system of the gastrointestinal tract and the immunological mechanisms underlying IgE-mediated food allergy, but will also introduce cells recently identified to have a role in the hypersensitivity reaction to food allergens. These include IL-9 producing mucosal mast cells (MMC9s) and type 2 innate lymphoid cells (ILC2s). The involvement of these cell types in potentiating the type 2 immune response and developing the anaphylactic response to food allergens will be discussed. In addition, it has become apparent that there is a collaboration between these cells that contributes to an individual's susceptibility to IgE-mediated food allergy.

Cavity-type Beam Position Monitors for Future Accelerators (차세대 가속기용 공동형 빔위치 측정기 개발)

  • Kim S.H.;Park Y.J.;Hwang W.H.;Huang J.Y.;Honda Y.;Inoue Y.
    • Journal of the Korean Vacuum Society
    • /
    • v.15 no.4
    • /
    • pp.331-337
    • /
    • 2006
  • Cavity-type beam position monitors were developed in collaboration with KEK to use for the future accelerators such as international linear collider (ILC) or x-ray free electron laser (XFEL) in PAL. BPM components such as BPM cavity, beam tubes, waveguides and feedthroughs were assembled by brazing at the same time to reduce mechanical errors during the fabrication. There are four screwed pins around outer rim of the cavity for the tuning of cavity frequency and x-y isolation. The resonance frequency of BPM is 6.422 GHz, the inner diameter of cavity is 53.822 mm, and the range of mechanical adjusting is $+ / - 250{\mu}m$. The x-y isolation was measured better than -40 dB after tuned. Test results of signal forms, x-y isolations, sensitivities are satisfied within requirements for the KEK ATF2 beam line.

밀배아 분말첨가가 식빵의 품질특성에 미치는 영향

  • 김래영;전순실;서재수
    • Proceedings of the Korean Journal of Food and Nutrition Conference
    • /
    • 2000.12a
    • /
    • pp.51-51
    • /
    • 2000
  • 식생활의 서구화로 제빵 산업이 발달하고, 빵을 주식으로 하는 인구가 늘고 있다 또한 기존의 재료보다는 기능성이 첨가된 부재료를 활용한 건강 지향적인 식품의 수요가 증가하고 있는 추세이다. 최근 밀배아의 용도 다양화를 위하여 팔은 연구가 진행되고 있으며, 상업적으로 이용되고 있다. 소맥의 제분과정에서 부산물로 얻어지는 밀배에는 식물 중에서 가장 많은 천연 비타민 E 복합체가 이상적인 상태로 함유되어 있다. 밀배아에 들어 있는 비타민 E는 천연 비타민 E 복합체와 합성 비타민 E로 구분되어진다. 천연비타민E는 8가지 이성체를 가진 자연 비타민 E를 말하며, 4종류의($\alpha$$\beta$${\gamma}$$\delta$)의 토코페롤과 4종의 토코페롤의 복합체이다. 비타민 E는 사람을 포함한 고등동물에 필수적인 영양소로 식물성기름, 곡류, 배아 등에 많이 들어 있으며, 여러 이성질체중 $\alpha$-토코페롤이 체내에서 가장 생물학적 활성이 큰 것으로 알려졌으며, 생체막조직에서 인지질의 천연항산화제 역할을 하여 체내대사를 정상으로 유지하는데 큰 기능을 하는 것으로 보고되고 있다. 우리나라에서 식용으로 소비되는 밀은 거의가 수입에 의존하고 있으며, 밀배아는 거의 전량이 가축의 사료용으로 사용되고 있고 근래에 와서는 배아유, 배아떡, 복합 조미료, 쿠키, 배아를 첨가한 국수 등에 이용되고 있다. 따라서 본 실험에서는 식빵제조시 밀배아 분말을 0, 2, 4, 6, 8, 10%씩 첨가하여 기능성 식빵을 제조하였을 때의 반죽의 물성, 호화특성을 살펴보고 빵으로 제조하였을 때의 식빵의 품질 특성으로서 1차 발효 손실률, 굽기 손실률, 부피, 질감, 노화도, 관능적 특성 및 mould-free shelf life를 측정하였다.te, ferric citrate가 유제품에 사용하기에 적합한 것으로 나타났다. 생이용성을 평가하기 위하여 우유에서 low molecular weight components(ILC)를 분리하고 철분과 복합체를 형성시킨 다음, 철분 결핍된 쥐의 소장에서 loop을 형성시켜 ILC-철분 복합체를 injection하여 철분 흡수도를 조사하였다. Ferrous lactate 100ppm에서 약 25.6%흡수되었고 ferric citrate 100ppm은 24.7%, ferrous sulfate는 19.7%흡수되었다. ILC를 첨가하지 않은 100ppm 철분염 용액은 ferrous sulfate를 제외하고는 흡수도가 감소되었다. 철분 결핍된 쥐에게 gavage 방법에 의하여 철분강화우유를 투여하였을 때 철분 25ppm 시료에서는 ferrous sulfate가 12.5%로 가장 높았고 ferrous lactate는 8.1%, ferric citrate는 6.5% 흡수되었다. 철분 100ppm수준에서는 흡수율이 낮아져 ferrous sulfate는 25ppm 시료보다 절반이하 수준이었다. Ferric citrate는 차이가 거의 없었으며 ferrous lactate는 70%수준이었다. 이상의 결과에서 철분강화우유에 사용하기 적합한 철분염은 ferrous lactate, ferric citrate였는데 특히 ferrous lactate는 제품의 이화학적 품질, 생이용성 측면 모두에서 가장 좋은 것으로 나타났다.다 높았으며, 1회당 평균 8.1$\pm$5.1개의 난포란을 회수하였다. investigation can be separated into sampling and analytical uncertainties, it can be used as a criterion where the resources for the inves

  • PDF