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Safety Assessments between Commercial Milk and DHA Fortified Milk of Dairy Cows Fed Feeds Containing Protected Fish Oil Treated with Formaldehyde (시중 일반우유와 포름알데히드로 보호 처리된 어유 첨가 사료를 먹인 DHA 강화우유의 안전성 연구)

  • Chun, Su-Hyun;Nam, Mi-Hyun;Hong, Chung-Oui;Yang, Sung-Yong;Yoo, Jin-Ah;Seo, Dong-Won;Chung, Il-Joong;Lee, Kwong-Won
    • Journal of Food Hygiene and Safety
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    • v.26 no.4
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    • pp.349-354
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    • 2011
  • Our objective in this study is to assess the safety of docosahexaenoic acid (DHA) fortified milk of dairy cows fed feeds containing protected fish oil treated with formaldehyde by analyzing formaldehyde concentration in commercial milk and DHA fortified milk of dairy cows fed formaldehyde treated feed. There are 3 milk samples in this study: Commercial milk (CM), DHA fortified milk for Kid (DHA-K) and DHA fortified milk for Baby (DHA-B). We confirm the fresh quality of these three samples by physicochemical tests. In fat content result, three groups are significantly different at the p < 0.05 by Duncan's multiple range test, but fat content of group DHA-K is about half the level of the other two groups. Protein content of group DHA-K is 1 % higher than other two groups. According to the analysis result of DHA content of DHA fortified milk, DHA content of DHA-B is two-fold higher than DHA-K. Similar pattern was seen in the intake based on age. According to HPLC analysis result of formaldehyde concentration in milk, commercial milk and DHA fortified milk are between 0.013 ppm and 0.057 ppm which is formaldehyde standard level in fresh milk settled in WHO (World Health Organization). Three groups have no significantly differences at the p < 0.05 by Duncan's multiple range test. For this reason, it can be concluded that there is no transition of formaldehyde from dairy cows fed formaldehyde treated feeds to its produced milk. Safety about formaldehyde of DHA fortified milk of dairy cows fed formaldehyde treated feeds is considered similar to commercial milk.

Method Validation for Determination of Lignan Content in Fermented Sesame by Bioconversion (생물전환된 참깨 발효물의 Lignan 화합물의 분석법 검증)

  • Jung, Tae-Dong;Kim, Jae-Min;Choi, Sun-Il;Choi, Seung-Hyun;Cho, Bong-Yeon;Lee, Jin-Ha;Lee, Sang Jong;Park, Seon Ju;Heo, In Young;Lee, Ok-Hwan
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.46 no.5
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    • pp.646-652
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    • 2017
  • The aim of this study was to investigate method validation for determination of sesamol, sesamin, and sesamolin in non-fermented sesame and fermented sesame by bioconversion. For validation, the specificity, linearity, precision, accuracy, limits of detection (LOD), and quantification (LOQ) of sesamol, sesamin, and sesamolin were measured by HPLC. Linearity tests showed that the coefficients of calibration correlation ($R^2$) for sesamol, sesamin, and sesamolin were 0.9999. Recovery rates of lignan contents in non-fermented and fermented sesame were high in the ranges of 100.27~115.10% and 98.43~114.90%, respectively. The inter-day and intra-day precisions of sesamin and sesamolin analyses for non-fermented and fermented sesame were 0.27~1.94% and 0.25~0.69%, respectively. The LOD and LOQ were $0.23{\sim}0.34{\mu}g/g$ and $0.70{\sim}1.03{\mu}g/g$, respectively. These results indicate that the validated method is appropriate for the determination of sesamol, sesamin, and sesamolin.

The Ecosystem of the Southern Coastal Waters of the East Sea, Korea I. Phytoplankton Community Structure and Primary Productivity in September, 1994 (한국 동해 남부 연안생태계 연구 1. 1994년 9월에 있어서의 식물플랑크톤의 군집구조와 1차생산력)

  • LEE Joon-Baek;HAN Myung-Soo;YANG HanR-Seob
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.1
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    • pp.45-55
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    • 1998
  • Phytoplankton community and primary productivity have been investigated in a fall season in the southern coastal waters of the last Sea, Korea. A strong thermocline formed at the 20\~60\;m$ layer and a cold water mass also existed in the bottom around Yong-il Bay. The offshore of the surveyed area was likely to be influenced by relatively warmer water, whereas the inshore represented Higher primary productivity with lower water temperature and lower salinity. A total of 133 species of phytoplankton occurred, representing 107 spp. of diatom, 23 spp. of dinoflagellate 3 spp. of silicoflagellate. Skeletonema costatum and Asterionellepsis glacialis were most predominant with more than $30\%$ dominance ratio, while Leptocylindrus danicus was also dominant at all transect lines. Standing crops of phytoplankton ranged from $2.7{\times}10^3\;to\;141.6{\times}10^3\;cell^{\ell-1}$. Chlorophyll a concentration varied with stations and layers, but the $30\~50$ m layer showed maximun with about $1.18{\mu}g{\ell}^{-1}$ rather than at the surface layer. It is believed that the maximun in standing crops and chlorophyll of phytoplankton formed at the $20\~50$ m layer above the thermocline during the survey. Phytoplankton primary productivity ranged from 0.32 to 3.04 mgC $m^{-3}\;hr^{-1}$, showing higher at the inshore than at the offshore. The range of integrated primary productivity was $263.3\~1085.5 mgC\;m^{-2}\;day^{-1}$ for the euphotic layer. Photosysthesis rates varied with the range from 0.76 to 8.04 mgC mgChl $\alpha^{-1}\;hr^{-1}$. Phytoplankton photosynthesis at the inshore was saturated at lower irradiance ($15\~35\%$ of surface) and showed higher efficiency, Thus, it revealed that the phytoplankton community probably adapted to the middle of euphotic layer because the depth of mixing layer became thinner due to the formation of thermocline.

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Recent Progress in Air Conditioning and Refrigeration Research: A Review of Papers Published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2006 (공기조화, 냉동 분야의 최근 연구 동향: 2006년 학회지 논문에 대한 종합적 고찰)

  • Han, Hwa-Taik;Shin, Dong-Sin;Choi, Chang-Ho;Lee, Dae-Young;Kim, Seo-Young;Kwon, Yong-Il
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.20 no.6
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    • pp.427-446
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    • 2008
  • A review on the papers published in the Korean Journal of Air-Conditioning and Refrigeration Engineering in 2006 has been accomplished. Focus has been put on current status of research in the aspect of heating, cooling, ventilation, sanitation and building environments. The conclusions are as follows. (1) The research trends of fluid engineering have been surveyed as groups of general fluid flow, fluid machinery and piping, etc. New research topics include micro heat exchanger and siphon cooling device using nano-fluid. Traditional CFD and flow visualization methods were still popular and widely used in research and development. Studies about diffusers and compressors were performed in fluid machinery. Characteristics of flow and heat transfer and piping optimization were studied in piping systems. (2) The papers on heat transfer have been categorized into heat transfer characteristics, heat exchangers, heat pipes, and two-phase heat transfer. The topics on heat transfer characteristics in general include thermal transport in a cryo-chamber, a LCD panel, a dryer, and heat generating electronics. Heat exchangers investigated include pin-tube type, plate type, ventilation air-to-air type, and heat transfer enhancing tubes. The research on a reversible loop heat pipe, the influence of NCG charging mass on heat transport capacity, and the chilling start-up characteristics in a heat pipe were reported. In two-phase heat transfer area, the studies on frost growth, ice slurry formation and liquid spray cooling were presented. The studies on the boiling of R-290 and the application of carbon nanotubes to enhance boiling were noticeable in this research area. (3) Many studies on refrigeration and air conditioning systems were presented on the practical issues of the performance and reliability enhancement. The air conditioning system with multi indoor units caught attention in several research works. The issues on the refrigerant charge and the control algorithm were treated. The systems with alternative refrigerants were also studied. Carbon dioxide, hydrocarbons and their mixtures were considered and the heat transfer correlations were proposed. (4) Due to high oil prices, energy consumption have been attentioned in mechanical building systems. Research works have been reviewed in this field by grouping into the research on heat and cold sources, air conditioning and cleaning research, ventilation and fire research including tunnel ventilation, and piping system research. The papers involve the promotion of efficient or effective use of energy, which helps to save energy and results in reduced environmental pollution and operating cost. (5) Studies on indoor air quality took a great portion in the field of building environments. Various other subjects such as indoor thermal comfort were also investigated through computer simulation, case study, and field experiment. Studies on energy include not only optimization study and economic analysis of building equipments but also usability of renewable energy in geothermal and solar systems.

Characteristics of Panicle Traits for 178 Rice Varieties Bred in Korea (국내에서 육성된 벼 품종들의 이삭형질 특성)

  • Park, Hyun-Su;Kim, Ki-Young;Mo, Young-Jun;Choung, Jin-Il;Kang, Hyun-Jung;Kim, Bo-Kyung;Shin, Mun-Sik;Ko, Jae-Kwon;Kim, Sun-Hyung;Lee, Bu-Young
    • Korean Journal of Breeding Science
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    • v.42 no.2
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    • pp.169-180
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    • 2010
  • This study was conducted to investigate characteristics of panicle traits which are important factors affecting yield and grain quality of rice. Twelve panicle traits in 178 Korean rice varieties composed of 160 Japonica type varieties and 18 Tongil type varieties were investigated. Tongil type varieties had longer panicle and thicker neck node than Japonica type varieties. Other traits such as number of total spikelets, total rachis-branches, secondary rachis-branches (SRBs) per panicle, total spikelets on SRBs per panicle, mean number of spikelets on a SRB, and mean number of SRBs per primary rachis branch (PRB) in Tongil type varieties were also higher than in Japonica type varieties. On the other hand, Japonica type varieties were shown to have well exserted panicle and little more mean number of spikelets on a PRB than Tongil type varieties. According to cluster analysis based on 12 panicle traits, 178 varieties were divided into four main groups. Group I had 133 Japonica type varieties and was characterized by relatively well exserted short panicle, small thickness of neck node, few rachis-branches and little sink size than other group. Group II was composed of 24 Japonica type varieties and 6 Tongil type varieties showing medium value and range between Group I and III. Group III included 11 Tongil type varieties and 1 Japonica type variety 'Baegjinju1' characterized by relatively poor exserted long panicle, big thickness of neck node, many rachis-branches and large sink size. Group IV was solely composed of 'Nongan', which had well exserted long panicle, big thickness of neck node, many rachis-branches and large-sink size. In correlation analysis, number of total spikelets per panicle showed very high correlation with the number of total rachis-branches per panicle (r=0.975), number of spikelets on SRBs per panicle (0.962), number of SRBs per panicle (0.959), mean number of SRBs per PRB (0.746) and mean number of spikelets on SRBs (0.738).

A Study on the Current Status of Prescribed Drugs in Oriental Health Insurance and their Improvement (한방건강보험 약제 투약 실태 및 활성화 방안 연구)

  • Kwon, Yong-Chan;Yoo, Wang-Keun;Seo, Bu-Il
    • The Korea Journal of Herbology
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    • v.27 no.2
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    • pp.1-16
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    • 2012
  • Objective : To investigate the current status of prescription drugs in Oriental medical institutes and to draw up a future plan for the revitalization of Oriental medical health insurance, this survey has been performed. Method : The survey has been made with 321 doctors working at Oriental medical institutes in Daegu and Kyungbuk areas for a period of 3 month from June 1, 2010 until September 1, 2010. Result : 1. When it comes to the current status of the use of herbal drugs in Oriental Health insurance, most of doctors surveyed prescribe insurance drugs, and they prescribe insurance drugs to patients, who are less than 20% of total patients visiting their clinics. 2. The awareness of Herbal Health Care Drugs is investigated. When it comes to the understanding of the difference between insurance drugs(powder type drugs) and granular type drugs, doctors admit that they differ only in one aspect, whether or not their being covered by health insurance. Based on the survey results on the understanding of insurance coverage of granular type drugs, doctors, even though they long for granular type drugs to be accepted as insurance drugs, are worrying whether the number of outpatients might dwindle due to increased insurance co-payments. They also point out that the biggest obstacles in the expansion of the granular type drugs as insurance drugs are the lack of understanding of the government and the objection of the Health Insurance Review and Assesment service (HIRA) for fear of increased insurance claims. 3. Upon investigation on Oriental medicine doctors' understandings of herbal pharmaceutical industry, it is found that doctors' responses on pharmaceutical industry are not all positive ones('new product development and neglect of R&D infrastructure' and 'smallness of industry'). When it is investigated what area needs the greatest improvement in herbal pharmaceutical industry, 'securing sufficient capital, good manufacturing, and strengthening quality control', is the highest. 4. When it is asked what are the most needed in order to improve herbal health insurance medicine, responses such as 'the increase in the accessibility to and the utilization of Oriental medical clinics through the diversification of the means of prescriptions', 'the improvement of insurance benefits(cap adjustments)', 'increase the proportion of high quality medicinal plants', 'the ceiling of co-payments(deductible) at 20,000 won or more', 'expansion of the choices of formulations', 'formulational expansions of tablets and pills', and finally 'admittance and expansion of granular type drug as insurance drug' are the highest. 5. Upon investigating the general characteristics of the current status of the usage of Oriental health care herbal drugs, the followings are observed. First, the frequency of use of health insurance drugs by the doctors who use health insurance with general characteristics shows similar differences in case of total monthly sales amount (p<0.001), average number of daily patients (p<0.05). Secondly, as to the willingness of the expanded usage of insurance drugs, similar differences are observed in case of total monthly sales amount (p<0.05). 6. Upon investigating the general characteristics of the perception of Herbal health care drugs, the followings are observed. First, inspecting general characteristics and insurance claims due to increased co-payments(deductible amount) reveals similar differences in case of working period (p<0.01) and in case of total monthly sales amount (p <0.01). Secondly, inspecting general characteristics and the obstacles that hinder granular type drugs from being accepted as health care insurance drugs shows similar differences in case of working period (p<0.05). 7. Upon investigating the general characteristics of the understanding of Oriental Herbal pharmaceutical companies, the followings are observed. First, opinions on the general characteristics of pharmaceutical companies, when examined with variance analysis, shows similar differences in case of total monthly sales amount (p<0.05). Secondly, when opinions are examined on general characteristics and the problems of herbal pharmaceutical companies, similar differences are found in case of working period (p<0.01) and in case of total monthly sales amount (p<0.001). Lastly, opinions on the general characteristics and reforms of pharmaceutical companies, similar differences are observed in case of working period (p<0.001). 8. Upon investigating the general characteristics of the improvement of insurance Herbal drugs, the followings are observed. First, regarding general characteristics and insurance benefits, similar differences are observed in case of working period (p<0.05), in case of total monthly sales amount (p<0.05), and in case of average number of daily patients (p<0.01). Secondly, opinions on the general characteristics and the needs for the improvement of Herbal insurance drugs are examined in 5 different aspects, which are the approval of granular type drugs as insurance drugs, the expanded practices of the number of prescription insurance drugs, the needs of a variety of formulations, the needs of TFT of which numbers of Oriental medical doctors are members for the revision of the existing system, and the needs of adjusting the current ceiling of the fixed amount and the fixed rate. When processed by the analysis of variance, the results show similar differences in case of average number of daily patients (p<0.01). Conclusion : From the results of this study the first measures to take are, to reform overall insurance benefit system, including insurance co-payment system(fixed rate cap adjustment), to expand the number of the herbal drugs to be prescribed matching with insurance benefit accordingly, and to revitalize herbal medicine insurance system through the change of various formulations. In addition, it is recommended to improve the effectiveness of herbal medicine by making plans to enhance the efficacy of herbal medicine and by enabling small pharmaceutical companies to outgrow themselves.