• 제목/요약/키워드: IL-la

검색결과 328건 처리시간 0.028초

선박용 탱크 모니터링 시스템 개발에 관한 연구 (A Study on Development of Marine Tank Monitoring System)

  • 원라경;류길수;김주원;성창규;박종일;김태진
    • 한국마린엔지니어링학회:학술대회논문집
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    • 한국마린엔지니어링학회 2006년도 전기학술대회논문집
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    • pp.65-66
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    • 2006
  • As industrial technology recently, a field of marine engineering is demanding integration and manless system. In this study, tank monitoring system is developed, which is able to watch real-time the marine tank for measuring a level, pressure, temperature. The system will provide efficiently measuring data for operator.

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희토원소 세륨과 란타늄의 첨가가 육계 생산성, 영양소 소화율, 도체 성상과 육색에 미치는 영향 (Effects of Dietary Supplementation of Cerium and Lanthanium on Growth Performance, Nutrient Digestibility, Carcass Characteristics and Meat Colors in Broilers)

  • 조종관;윤구;김영우;김진수;김광현;권일경;채병조
    • 한국가금학회지
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    • 제36권4호
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    • pp.279-286
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    • 2009
  • 본 연구는 희토 성분인 Ce(cerium)과 La(lanthanium)의 단독 또는 혼합 급여가 실용 육계의 생산성, 영양소 소화율, 골격성분, 그리고 도체 성상과 육색에 미치는 영향을 조사하기 위하여 1일령 Hubbard종 암평아리(체중 45 g) 1,600수를 공시하여 4처리 4반복으로 반복당 100수씩 완전 임의 배치하였다. 4개 처리구는 T1, 무첨가 대조구; T2, Ce 100 ppm 첨가구; T3, La 100 ppm 첨가구; T4, Ce 100 ppm과 La 100 ppm 혼합 첨가구로 하였으며, 전기(0~3주)와 후기(4~5주)로 나누어 5주간의 사양 시험을 실시하였다. 전기의 증체량은 T4에서 다른 처리구에 비하여 다소 높았으며, 대조구에 비해서는 유의하게 높았다(p<0.05). 전체 기간에서도 T4의 증체량이 가장 높았지만 통계적 유의성은 인정되지 않았다(p>0.05). 사료 섭취량은 각 단계 및 전체기간에서 처리구간 유의적인 차이가 나타나지 않았다(p>0.05). 사료 요구율은 전기에서 T4가 T3에 비하여 개선되었으며(p<0.05), 후기에는 각 처리간에 차이가 없었지만(p>0.05) 전체기간으로 볼 때 T4가 대조구에 비하여 유의적으로 개선되었다(p<0.05.). 소화율에서 건물 소화율은 T3에서 가장 높았으며(p<0.05) T2와 T4도 대조구에 비하여 개선되었다(p<0.05). 조단백질 소화율은 T3가 가장 높았으며(p<0.05), T2에서도 대조구에 비해 개선되었다(p<0.05). 조회분, 에너지, 칼슘과 인의 소화율도 T3에서 가장 높게 나타났다(p<0.05). 뼈의 성분 분석에서 칼슘의 함량은 Ce과 La을 급여한 처리구가 대조구에 비해 높게 나타났지만 처리구간 유의적인 차이는 나타나지 않았으며(p>0.05), 도체 성상 조사와 육색의 측정에서도 처리구간 유의적인 차이는 나타나지 않았다(p>0.05). 본 연구의 결과, 육계 사료내 La의 첨가는 영양소 소화율을 뚜렷하게 개선하였다. 또한 육계 사료내 Ce과 La의 첨가는 육계의 소화율을 개선시켰으며, 육성 초기의 증체량과 사료 요구율 개선에 효과가 있는 것으로 판단된다.

Dexmedetomidine Modulates Histamine-induced Ca2+ Signaling and Pro-inflammatory Cytokine Expression

  • Yang, Dongki;Hong, Jeong Hee
    • The Korean Journal of Physiology and Pharmacology
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    • 제19권5호
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    • pp.413-420
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    • 2015
  • Dexmedetomidine is a sedative and analgesic agent that exerts its effects by selectively agonizing ${\alpha}2$ adrenoceptor. Histamine is a pathophysiological amine that activates G protein-coupled receptors, to induce $Ca^{2+}$ release and subsequent mediate or progress inflammation. Dexmedetomidine has been reported to exert inhibitory effect on inflammation both in vitro and in vivo studies. However, it is unclear that dexmedetomidine modulates histamine-induced signaling and pro-inflammatory cytokine expression. This study was carried out to assess how dexmedetomidine modulates histamine-induced $Ca^{2+}$ signaling and regulates the expression of pro-inflammatory cytokine genes encoding interleukin (IL)-6 and -8. To elucidate the regulatory role of dexmedetomidine on histamine signaling, HeLa cells and human salivary gland cells which are endogenously expressed histamine 1 receptor were used. Dexmedetomidine itself did not trigger $Ca^{2+}$ peak or increase in the presence or absence of external $Ca^{2+}$. When cells were stimulated with histamine after pretreatment with various concentrations of dexmedetomidine, we observed inhibited histamine-induced $[Ca^{2+}]_i$ signal in both cell types. Histamine stimulated IL-6 mRNA expression not IL-8 mRNA within 2 hrs, however this effect was attenuated by dexmedetomidine. Collectively, these findings suggest that dexmedetomidine modulates histamine-induced $Ca^{2+}$ signaling and IL-6 expression and will be useful for understanding the antagonistic properties of dexmedetomidine on histamine-induced signaling beyond its sedative effect.

피뢰설비 열화진단 전문가 시스템의 설계 방법론 (Design Methodology of Expert System for aging diagnosis of Arrester)

  • 김태진;류길수;길경석;성창규;김일권;박종일;원라경
    • 한국마린엔지니어링학회:학술대회논문집
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    • 한국마린엔지니어링학회 2006년도 전기학술대회논문집
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    • pp.69-70
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    • 2006
  • The arrester's condition is related directly to protected equipment's safety. The most important is, therefore, arrester aging diagnosis. In this study, arrester aging diagnosis expert system is implemented to use JESS shell-engine and the leakage current detection technique.

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Effect of benzo(a)pyrene and mitomycine C on HeLa cell division cycle

  • Yu, Il-Je;Lim, Cheol-Hong;Kim, Hyo-Jung;Chung, Kyu-Hyuk;Song, Kyung-Seuk;Han, Jeong-Hee;Chung, Yong-Hyun
    • 한국환경성돌연변이발암원학회지
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    • 제21권2호
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    • pp.82-88
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    • 2001
  • Recently, there has been significant progress in understanding the control process of the cell division cycle. To investigate the influence of toxic substances on the cell cycle, the effect of benzo(a)pyrene (BAP) and mitomycine C (MMC) on synchronized HeLa cells was analyzed during the cell cycle. To synchronize the HeLa cells, 10$^{6}$ cells were grown for 1 day and then treated with 1 mM hydroxyurea for 14 h. The arrested cells were then allowed to proceed through their cell cycle by removing the hydroxyurea and resupplying a fresh medium. The arrested cells in the G1/S transition then proceeded to the S phase after 4 h, the G2/M phase after 8h, and the G1 phase after 12 h, subsequent to the resupply of a fresh medium. In the untreated HeLa cells, the p34$^{cdc2}$ kinase activity, measured using a p34$^{cdc2}$ specific peptide, peaked after 8h (G2/M) and then declined after 12 h (G1). However, treatment with 30 $\mu$M BAP delayed the peak of the p34$^{cdc2}$ kinase activity. The amount of p34$^{cdc2}$ remained unchanged in the untreated, BAP-, and MMC-treated cells throughout the cell cycle. The cyclin B level peaked after 8 h in the untreated cells, yet peaked after 10-12 h in the BAP-treated cells. There was no significant change in the cyclin B level in the MMC-treated cells.

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