• Biomolecules & Therapeutics
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• v.6 no.1
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• pp.31-36
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• 1998

Capsular polysaccharides (CPs) from Streeptococcus pneumoniae were examined for the ability to induce secretory responses in a pure population of peritoneal macrophages. The highly purified CPs were able to affect the macrophage, ie, secretion of tumor necrosis factor-alpha (TNF-$\alpha$) and nitrite. As after stimulation with CPs, secretion of TNF-u induced by these CPs reached its maximum within the first few hours of the interaction, while secretion of nitrite was increased with time. In addition, production of TNF-$\alpha$ and nitrite was increased in a dose-dependent manner. In the presence of indomethacin, CP-stimulated TNF-$\alpha$ production was not altered. In contrast, LPS with indomethacin stimulated 24.5% more TNF-$\alpha$ than LPS alone, suggesting that the intracellular signaling processes for TNF production are differentially stimulated by CP and LPS. The results demonstrate that CPs are potent inducer of macrophage secretory activities.

• Journal of Environmental Health Sciences
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• v.30 no.1
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• pp.59-64
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• 2004

This study was carried out to investigate influencing factors of bisphenol A(BPA) removal characteristic in conventional water treatment systems to be connected with coagulation, sedimentation, filtration and disinfection. The result are summarized as follows; In BPA removal, optimal doses of PAC, alum, ferric chloride were 7.5 mg Al/L, 10.0 mg AI/L, 15.0 mg Fek. PAC was most effective coagulant to remove BPA. In coagulation process, BPA removal efficiency were increased about 2％ by adjusting pH of raw water as 6. At temperature rise 1$0^{\circ}C$, BPA removal efficiency were increased 0.94％. but BPA removal efficiency in sand filtration process were under 1 ％ie, so that BPA was almost not removed. At free chlorine dose 1, 2 mg/L, the reaction rate constant k in the BPA removal have been calculated to be 0.397, 0.953 min$^{-1}$ . At free chlorine dose 1, 2 mg/1-, degradation reaction of BPA was completed during 10 min and BFA removal efficiencies were 97.66, 99.99％ at this time.

• IE interfaces
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• v.12 no.4
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• pp.487-495
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• 1999

Mobile telecommunication service is one of the most competitive and rapidly growing industries in Korea. In competitive environments, it is essential to measure and improve customer satisfaction(CS) levels. However, there are a few problems in existing methods of CS measurement. First, sacrifice such as price is not included properly. Thus, the CS is not expanded into the value concept which is important to customer's behavioral intention. Second, CS measurements are not benchmarked with other competitive companies and CS index cannot reflex it properly. AT&T experienced these problems and suggested customer value added (CVA) for CS measurement. In this study, we try to introduce the CVA concept into our mobile telecom services. CS attributes were constructed, an survey was conducted for 5 mobile telecom companies, CS survey results were presented, and the validity of CVA concept was discussed.

• IE interfaces
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• v.12 no.4
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• pp.575-585
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• 1999

This study develops and operating software for a model plant. The model plant consists of an AS/RS system, two machining centers, an assembly line, and supplementary material handling equipments. Devices of each component are connected with the IBS RT24 DIO 16/16-T I/O module. Each I/O module communicates digital signals with the INTERBUS controller board via SUB-D 9 Connector cable. This study is a previous stage for developing an educational CIM software. Petri Nets is used for modelling the storage/retrieval of the AS/RS system, the flow of workpieces and the assembly line for parts. The operating software is coded with Microsoft Visual $C^{++}$ 5.0 and Interbus Library which is a software driver for the controller board. The operating software can be run on a MS Windows 95. Microsoft Access is used for the implementation of databases for BOM, AS/RS, and parts.

• IE interfaces
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• v.12 no.3
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• pp.374-381
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• 1999

In this paper, we propose an architecture of the DNC system for Shop Floor Control/Point of Production(SFC/POP). The DNC system to be presented this paper retrieves line-up sheets which include the drawing information, making a index database for line-up sheets, NC programs and tool adjustment data. And it is interface with a raw material, jig and tool information. Also, the DNC system transmits operation information to real workers rapidly, and supports realtime monitoring by collecting the state information of machines directly. In the analysis and design phases, this paper models realtime events using the state transition diagrams. In the implementation phase, we use the ORACLE DBMS(Database Management System) as the DBMS and Developer 2000 and Microsoft Visual C++ 5.0 as the programming tools.

• IE interfaces
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• v.10 no.2
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• pp.99-107
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• 1997

The purpose of accident analysis is to obtain accurate and objective information about the causes of accidents in order to prevent accidents from reoccurring. This study investigated the characteristics and causes of occupational accidents in Korean industry by comparison with those of Japan and U.S.A The results show that there are some characteristics in the accidents of Korean industry; (1)larger companies tend to have lower accident rates than the smaller ones; (2) inexperience is related to high accident rates; (3) 'awkward or sudden movement' and 'caught in and between object' represents the leading accident type; (4) the body sites most vulnerable to injury are the hands and fingers; and (5) 'fractures' is the leading injury type. These findings identified in this study can be used to prevent the industrial accidents.

• IE interfaces
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• v.5 no.2
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• pp.53-74
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• 1992

In order to design an FMS(Flexible Manufacturing System), an effective design tool is necessary for selecting and anlayzing the complex interacting factors of a manufacturing system. Considering most of the previous researches have been focused on evaluating the designed FMS, development of an integrated FMS designing system is needed for performing the design task such as machine selection and layout determination as well as the evaluation task of the designed FMS. In this paper, we developed a prototype of such a system called the intelligent FMS designer based on the techniques of Expert System and Simulation. By using this designing system, possible design alternatives can be analyzed and appropriate manufacturing capacity can be estimated at the designing stage. Various operating characteristics of the designed FMS can be also predicted before it is implemented. Eventually a suitable design alternative can be provided with cost details within relatively short time period. To demonstrate the performance and effectiveness of the designer, a simple example is tested. The results show a great potential for automating design processes of an FMS.

• IE interfaces
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• v.5 no.2
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• pp.19-27
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• 1992

The ABC analysis is a widely used inventory control technique which consists of classifying inventory items into three categories according to annual dollar usage and concentrating managerial efforts on the high value items. But its major weakness is that the classification is somewhat arbitrary and is made in the light of single criterion, the annual usage. In this paper, a modified approach using TOPSIS is proposed where 1) the inventory items are ranked, rather than classified into three categories, in the order of relative importance and 2) the latter is determined by considering the multiple criteria such as annual usage, difficulty of procurement, lead time and shelf life. A case study was performed with the field data from a company producing electronical parts. The rank order produced by TOPSIS was judged quite reasonable by the company inventory control manager.

• IE interfaces
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• v.5 no.2
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• pp.29-37
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• 1992

An approach to Just-In-Time for small job-shop-type manufacturers is presented. This is aimed at those who understand the pull production system, however, cannot afford either swift changeover in workcenters or frequent delivery to customers. First, as a production planning technique, a lot-sizing model entitled Multilevel Least Total Cost Model(MLTCM) is developed; The production order quantities of each components be those requiremensts of the end item production lot. The contribution of MLTCM is shown via simulation. Then, a framework of the Kanban operations is designed; A Production Control Kanban is introduced as a communication tool with Production Kanban in a job-shop.

• IE interfaces
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• v.5 no.2
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• pp.39-52
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• 1992

This paper presents alternatives for facilities planning and analyses them using simulation approach. For this purpose, hydro-cylinder production line was sampled as a case study. Several facilities planning alternatives are evaluated based on the several factors such as line balancing, equipment utilization, optimum number of equipments, inventory size, flow time, bottleneck machine, and productive capacity. An optimal facilities planning is proposed based on the degree of meeting with the all factors evaluated. The simulation language employed in this study is SIMAN and the data used for simulation are provided by hydro-cylinder shop.