• Title/Summary/Keyword: ICG-Rmax

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Quantitative Evaluation of the Remaining Hepatic Function after Surgery in Patients with Hepatic Cancer using Deconvolution Technique of Tc-99m DISIDA SCAN (Tc-99m DISIDA SCAN에서 deconvolution 방법을 이용한 간암 환자의 수술 후 잔여 간 기능의 정량적 평가)

  • Kim, Deok-Won;Kim, Su-Chan;Yun, Seok-Jin;Lee, Jong-Du;Kim, Byeong-Ro
    • Journal of Biomedical Engineering Research
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    • v.18 no.3
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    • pp.301-306
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    • 1997
  • Surgical removal of hepatic cancerous tissues have been widely performed due to its early detection. However, a patient can not survive if excessive hepatic tissues were removed. Therefore, quantitative evaluation of remaining hepatic function after surgery is a really important factor for surgeon. the currently used ICG Rmax and Lidocaine clearance tests have disadvantages such as tedium, complexity, and inability to estimate remaining hepatic function after surgery. While HEF has advantages such as simplicity, quickness, nonivasiveness, and quantification, its reliability has been doubtful. Thus, the program for calculation of HEF has been developed from serial gamma camera image data. And we compared the reliability of HEF with ICG Rmax and Lidocaine clearance test using 6normal and 18 abnormal rabbits with damaged livers. The correlation coefficient of HEF to ICG Rmax and MEGX was 0.91, 0.94, respectively. I was also found that the HEFs of normal and abnormal hepatic tissues was higher than 100% and lower than 80%, respectively. Thus we confirmed that HEF can be a good indicator distinguishing between abnormal tissues and normal ones. Finally, we could conclude that patients would survive if both the pre-and the post-operative HEF were greater than 60%.

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Quantitative evaluation of rabbit's hepatic function using HEF, DISIDA-K, and R-max technique (HEF, DISIDA-K, R-max 방법을 이용한 토끼 간 기능의 정량적 평가)

  • Kim, D.W.;Kim, S.C.;Yun, S.J.;Lee, J.D.;Kim, B.R.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.05
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    • pp.161-163
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    • 1996
  • The correlation coefficients among hepatic extraction fraction(HEF), DISIDA-K, and ICG Rmax methods were found using two normal rabbits and four rabbits with damaged liver. The correlation coefficient between HEF and ICG R-max which is a standard technique in evaluating liver function was found to be 0.93. Therefore HEF is a valuable diagnostic method since it is not only accurate, but possible to estimate remaining liver function after surgical of cancerous hepatic tissue.

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