• 한국전산유체공학회:학술대회논문집
• /
• 한국전산유체공학회 2010년 춘계학술대회논문집
• /
• pp.86-92
• /
• 2010

A metal diaphragm compressor has been widely used for supplying a high pressures gas. This compressor mainly consists of gas oil space and metal diaphragm. Gas sucked in the gas space is compressed by an oscillating metal diaphragm existed between the gas and oil space. A non-return discharge and suction check-valve are components of the compressor that draw off the compressed oil and gas. Those components are self-actuated by differential pressures. Therefore, the rapid response and stable operating conditions are required. In the present study, to find out the dynamic behavior of the suction, discharge valve and diaphragm compressor, the unsteady flow field has been investigated numerically by using the unsteady two-way FSI (Fluid Structure Interaction) simulation method, $k-{\omega}$ turbulent model and mesh deformation.

• Asian-Australasian Journal of Animal Sciences
• /
• 제10권1호
• /
• pp.86-97
• /
• 1997

Purified diets containing 5 graded levels of methionine + cystine were fed to young, growing and finishing pigs to determine the methionine + cystine requirement for growth and maintenance. A model was developed to subdivide the methionine + cystine requirement for maintenance from requirement for growth. From this model, the methionine + cystine requirement for growth was 8.633, 10.260 and 9.293 g/kg live weight gain and the maintenance requirement was 0.049, 0.016 and 0.019 g per unit of metabolic body size at each stage of growth, respectively. In the young pigs, the methionine + cystine requirement for growth was 0.491 g/g N gain and the maintenance requirement was 0.059 g per unit of metabolic body size. The breakpoint of plasma methionine + cystine concentrations was 3.888, 6.935 and 8.116 g/d, respectively. Expected requirements obtained from these formulae were in general agreement with previous estimates. Based on the weight gain vs N gain equation, about 4.44% of the retained protein was comprised of methionine + cystine and compared to 3.31%, the mean methionine + cystine content of pig muscle CP.

• Asian-Australasian Journal of Animal Sciences
• /
• 제10권1호
• /
• pp.54-63
• /
• 1997

Purified diets containing 5 graded levels of lysine were fed to young and growing pigs to determine the lysine requirement for growth and maintenance. A model was developed to subdivide the lysine requirement for the maintenance from requirement for growth. From this model, the lysine requirement for growth was 18.018 and 19.431 g/kg live weight gain and the maintenance requirement was 0.115 and 0.033 g per unit of metabolic body size at each stage of growth, respectively. In the young pigs, the lysine requirement for growth was 0.950 g/g N gain and the maintenance requirement was 0.114 g per unit of metabolic body size. The breakpoint of plasma lysine concentrations was 8.695 and 13.464 g/d, respectively. Expected requirements obtained from these formulae were in general agreement with previous estimates. Based on weight gain vs N gain equation, about 7.92% of the retained protein was comprised of lysine as compared to 7.11%, the mean lysine content of pig muscle CP.

• 대한화장품학회:학술대회논문집
• /
• 대한화장품학회 2003년도 IFSCC Conference Proceeding Book I
• /
• pp.192-202
• /
• 2003

The wrinkles correspond to the most obvious expression of skin ageing and are manifested by changes on the organization and dermal structure. In the extracellular matrix, decreased quantities of collagens and glycosaminoglycans as well as a deterioration of the fibrillary network is noted, result in a reduction of dermal thickness. In addition, the activity of the collagenases increases in contrast to the synthesis of collagen fibers. Nor are cells spared during the aging process. We thus studied and compared the contractile capacity as well as the synthesis capacity of normal human fibroblasts and human fibroblasts obtained from biopsies of forehead wrinkles. The capacity of the fibroblasts to be adhered to the collagen network and to maintain a three-dimensional structure of dermis was studied on a model of equivalent dermis. The metabolic activity was studied by evaluating the capacities of synthesis of collagen I, main component of dermis. Human fibroblasts resulting from the forehead wrinkle contract less the gel of collagen than the normal human fibroblasts and present an activity of biosynthesis of collagen I less important than normal human fibroblasts. These results show that fibroblasts with aging present a deceleration of their metabolic activity and lose their capacity of adhesion to collagen fibers thus limiting the possibility of organizing the dermal tissue. We investigated the potential of an active ingredient able to compensate for the reduction of the metabolic activity and to restore the contractile capacity of fibroblasts obtained from forehead wrinkles. This effect was compared with a reference molecule: the vitamin C.

• 한국지구물리탐사학회:학술대회논문집
• /
• 한국지구물리탐사학회 2008년도 공동학술대회
• /
• pp.97-100
• /
• 2008

일본 후지산은 역사적, 지질학적, 그리고 최근의 지진학적 징후로부터 화산활동의 재개에 의한 재해가능성이 있어 화산감시연구가 집중되고 있다. 후지산 감시활동의 일환으로 축적된 방대한 주변지역 지진자료를 바탕으로 단일산란모델에 의한 코다감쇠상수($Q_c^{-1}$)와 다중시간창분석에 의한 고유 및 산란감쇠상수 ($Q_i^{-1}$, $Q_s^{-1}$)를 측정하였다. 본 연구는 후지산 아래에 존재하는 것으로 여겨지고 있는 용암체의 감쇠구조에 초점을 맞추기 위해 정상에서 반경 5km 이내의 지대를 지진파가 통과하는 '후지산 근방', 지진파 통과지역이 모두 반경 20 km 바깥인 '먼 후지산'으로 자료를 분류하였다. 본 연구는 자료가 풍부하여 비교적 작은 오차범위를 나타내고 있는데, '후지산 근방'의 모든 감쇠상수 수 $Q^{-1}$는 '먼 후지산'에 비해 컸으며, 두 지대 공히 고주파 영역에서의 $Q_i^{-1}$값은 $Q_s^{-1}$ 값에 비해 높은 값이었다. 그러나, '후지산 근방'의 $Q_i^{-1}$ 값은 다른 화산지역에 비해 낮았는데, 이는 하와이화산과 같은 활동적인 화산에 비해 용융도의 비율이 낮거나 마그마활동이 덜한 것으로 해석된다.

• Journal of Electrical Engineering and Technology
• /
• 제3권1호
• /
• pp.36-42
• /
• 2008

In a gas insulated substation (GIS), Very Fast Transient Over-voltages (VFTOs) are generated due to switching operations and ground faults. These fast transients are associated with high frequency components of the order of a few hundreds of MHz. These transients may cause internal faults i.e., layer-to-layer faults or minor faults in a capacitively graded bushing, which is one of the important pieces of terminal equipment for GIS. In the present study, the PSPICE model has been developed to calculate the voltage distribution across the layers of 420kV graded bushing for high frequency pulses of rise time 1 to 50ns, which simulate the VFTO. For this simulation, an equivalent electrical network of bushing with different equivalent layers has been considered. The effect of different equivalent layers modeling circuits on the non-uniform voltage factor has been analysed. The influence of copper strip inductance on voltage distribution across layers has also been analysed for various rise times of high frequency transients. Finally, the leakage current of the bushing is calculated for evaluating the bushing condition under these transients.

• Journal of Astronomy and Space Sciences
• /
• 제21권2호
• /
• pp.73-82
• /
• 2004

Samec et al.(1997)의 UBV 광도곡선과 Lu ＆ Rucinski(1999)의 시선속도곡선을 2003년에 개정한 Wilson-Devinney 쌍성모델을 적용하여 W형 과접촉쌍성 V417 Aql의 측광 및 분광학적 해를 새롭게 산출하였다. 광도곡선 분석에서 Qian(2003)이 제안한 제3천체의 광도를 광도곡선 분석에서 고려한 결과, 삼체의 광도가 U, B, V 필터에서 각각 2.7%, 2.2%, 0.4% 존재하고, 삼체의 광도를 고려한 경우가 그렇지 않은 경우보다 이론치와 관측치가 극심 부근에서 더 잘 일치하였다. 우리의 해로부터 V417 Aql의 절대 물리량을 $M_1$= 0.53 $M_{ }$, $M_2$= 1.45 $M_{*}$, $R_1$= 0.84 $R_{*}$, 그리고 $R_2$= 1.31 $M_{*}$으로, 거리를 216pc으로 산출하였다. 우리가 구한 거리는 Rucinski ＆ Duerbeck(1997)의 관계식 $M_{v}$ = $M_{v}$(log P, B-V)으로부터 계산한 거리(204pc)와 잘 일치하는 반면, Hipparcos 삼각시차에 의한 거리(131$\pm$40pc)보다 멀다. 그 차이는 Hipparcos 시차의 비교적 큰 오차 때문에 생긴 것일 수 있다. 수 있다.

• Journal of Biosystems Engineering
• /
• 제15권3호
• /
• pp.207-218
• /
• 1990

Grains display characteristics of both elastic bodies and viscous fluids when they are subjected to mechanical treatments in harvesting, handling, and processing. This viscoelastic behavior of grains when mechanically stressed must be fully understood to establish maximum machine efficiency and have a minimum degree of grain damage and the highest quality of the final product. The studies were conducted to examine the effect of the moisture content, the loading rate and the initial deformation on the stress relaxation behavior of whole kernel of rough rice, and develop the rheological model to represent its stress relaxation behavior. The following results were obtained from the study. 1. Moisture content had the greatest influence on the initial portion of the relaxation curve. With elapsing time the lower moisture content resulted in the lower residual stress for the Japonica-type rough rice and vice versa for the Indica-type rough rice. But within the ranges of moisture content tested, the degree of stress relaxation per unit strain on the Indica-type rough rice was a little higher than those on the Japonica-type rough rice. 2. The slower loading rate resulted in less initial stress. The decreasing trend of residual stress for all the samples tested with increasing loading rate was shown. 3. The higher initial deformation for all the samples resulted in less initial stress. The increasing of amount of stress relaxation per unit strain with increase of initial stress indicated that viscoelastic properties of rough rice depended not only upon duration of load applied but also initial stress applied. This means that rough rice is nonlinear viscoelastic material. 4. The compression stress relaxation properties of rough rice kernel can be described by a generalized Maxwell model representing by the Maxwell elements.

• 한국환경농학회지
• /
• 제10권2호
• /
• pp.167-177
• /
• 1991

O,S-dialkyl alkylphosphonothioates 계열 유기인제 농약의 체내 작용기작을 이해하기 위하여 model 화합물 (1), O-ethyl S-methyl ethylphosphonothioate [$LD_{50}$(rat, oral) 4.6mg/kg ; $K_i$(bovine erythrocyte acetylcholinesterase) 303 $M^{-1}min^{-1}$]이 선정되었다. 이 유기인계 화합물들은 체내에서 활성화(活性化) 과정을 겪으면서 독성(毒性)을 발현하는 것으로 가설(假說)되어져 왔다. 생체 내 mixed function oxidases에 의한 산화 활성화 과정을 화학적(化學的)으로 재현하기 위하여 두 종류의 유기산화제 즉, meta-chloroperoxybenzoic acid와 monoperoxyphthalic acid가 사용되었고, 대사적(代謝的) 산화를 재현하기 위하여 쥐 간(肝)에서 추출한 microsomal oxidation system을 이용한 in vitro 산화반응이 시도되었다. 산화반응 중간생성물인 S-oxide의 존재가 전구물질(1)의 가설적 산화 반응경로를 통해서 간접적으로나마 충분히 확인 되어질 수 있었다. 더욱이 ethanol을 이용한 trapping 실험에서 불안정한 산화중간물질인 S-oxide가 강한 phosphorylating agent라는 것이 확인되어, 전구물질 (1)로부터 산화반응을 거치면서 생성된 이 중간물질이 체내 신경전달에 중요한 역할을 하는 acetylcholinesterase를 phosphorylation하게 되고, 결국 이런 활성화 과정을 통해 이 계열의 화합물들이 독성을 발휘하는 것으로 이해될 수 있었다.

• 한국임상약학회지
• /
• 제27권4호
• /
• pp.258-266
• /
• 2017

Objective: To develop a population pharmacokinetics (PK)/pharmacodynamics (PD) model for alcohol in healthy volunteers and to elucidate individual characteristics to affects alcohol's PK or PD including dissolved oxygen. Methods: Following multiple intakes of total 540 mL alcohol (19.42 v/v%) to healthy volunteer, blood alcohol concentration was measured using a Breathe alcohol analyser (Lion SD-400 $Alcolmeter^{(R)}$). A sequential population PK/PD modeling was performed using NONMEM (ver 7.3). Results: Eighteen healthy volunteer were included in the study. PK model of alcohol was well explained by one-compartment model with first-order absorption and Michaelis-Menten elimination kinetics. $K_a$, V/F, $V_{max}$, $K_m$ is $8.1hr^{-1}$, 73.7 L, 9.65 g/hr, 0.041 g/L, respectively. Covariate analysis revealed that gender significantly influenced $V_{max}$ (Male vs Female, 9.65 g/hr vs 7.38 g/hr). PD model of temporary systolic blood pressure decreasing effect of alcohol was explained by biophase model with inhibitory $E_{max}$ model. $K_{e0}$, $I_{max}$, $E_0$, $IC_{50}$ were $0.23hr^{-1}$, 44.9 mmHg, 138 mmHg, 0.693 g/L, respectively. Conclusion: Model evaluation results suggested that this PK/PD model was robust and has good precision.