• Asian Pacific Journal of Cancer Prevention
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• v.15 no.18
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• pp.7583-7588
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• 2014

Background: Colorectal cancer (CRC) is a major cause of cancer-related death and cancer-related incidence worldwide. The potential of microRNA-21 (miR-21) as a biomarker for CRC detection has been studied in several studies. However, the results were inconsistent. Therefore, we conducted the present meta-analysis to systematically assess the diagnostic value of miR-21 for CRC. Materials and Methods: Using a random-effect model, the pooled sensitivity (SEN), specificity (SPE), positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were calculated to evaluate the diagnostic performance of miR-21 for CRC. A summary receiver operating characteristic (SROC) curve and an area under the curve (AUC) were also generated to assess the diagnosis accuracy of miR-21 for CRC. Q test and I2 statistics were used to assess between-study heterogeneity. Publication bias was evaluated by the Deeks' funnel plot asymmetry test. Results: A total of 986 CRC patients and 702 matched healthy controls from 8 studies were involved in the meta-analysis. The pooled results for SEN, SPE, PLR, NLR, DOR, and AUC were 57% (95%CI: 39%-74%), 87% (95%CI: 78%-93%), 4.4 (95%CI: 2.4-8.0), 0.49 (95%CI: 0.32-0.74), 9 (95%CI: 4-22), and 0.83 (95%CI: 0.79-0.86), respectively. Subgroup analyses further suggested that blood-based studies showed a better diagnostic accuracy compared with feces-based studies, indicating that blood may be a better matrix for miR-21 assay and CRC detection. Conclusions: Our findings suggest that miR-21 has a potential diagnostic value for CRC with a moderate level of overall diagnostic accuracy. Hence, it could be used as auxiliary means for the initial screening of CRC and avoid unnecessary colonoscopy, which is an invasive and expensive procedure.

• East Asian Journal of Business Economics (EAJBE)
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• v.4 no.1
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• pp.5-15
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• 2016

With vigorous development of global network community, smart phones and mobile devices, enterprises can rapidly collect various kinds of data from internal and external environments. How to discover valuable information and transform it into new business opportunities from big data which grow rapidly is an extremely important issue for current enterprises. This study treats Company S as the subject and tries to find the factors of big data application in enterprises by a modified Decision Making Trial and Evaluation Laboratory (DEMATEL) and perceived benefits - perceived barriers relation matrix as reference for big data application and management of managers or marketing personnel in other organizations or related industry.

• Journal of Sericultural and Entomological Science
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• v.37 no.2
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• pp.191-196
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• 1995

The aim of the present work is to investigate the level of faults present in tussah silk yarn as detected on an Uster instrument for four different varieties of commercially available tussah(tasar) silk yarns. The structure of these faults were analysed further so as to understand the mechanism and source of their generation.

• Honam Mathematical Journal
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• v.29 no.4
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• pp.701-721
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• 2007

Recently, a new singular function(NSF) method was posed to get accurate numerical solution on quasi-uniform grids for two-dimensional Poisson and interface problems with domain singularities by the first author and his coworkers. Using the singular function representation of the solution, dual singular functions, and an extraction formula for stress intensity factors, the method poses a weak problem whose solution is in $H^2({\Omega})$ or $H^2({\Omega}_i)$. In this paper, we show that the singular functions, which are not in $H^2({\Omega})$, also satisfy the integration by parts and note that this fact suggests the possibility of different choice of the weak formulations. We show that the original choice of weak formulation of NSF method is critical.

• The Journal of Asian Finance, Economics and Business
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• v.9 no.3
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• pp.229-234
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• 2022

The study aims to investigate whether Musharakah management has an impact on Chinese and Malaysian business partnerships. To estimate the relationship between Musharakah and the Sino-Malaysian partnership, this study uses a panel econometric technique namely pooled ordinary least squares. Ordinary Least Squares regression (OLS) is a common technique for estimating coefficients of linear regression equations which describe the relationship between one or more independent quantitative variables and a dependent variable. Data was retrieved from the annual reports (from 2009 to 2019) of non-financial firms listed on the stock exchange of China and Malaysia. Four partnership measures (i.e., Musharakah, Mudarabah, Tawuruq, and Kafalah) were used to estimate the impact of Musharakah on the Sino-Malaysian partnership. Empirical results reveal that Musharakah and Mudarabah are positively related to Kafalah but the relationship is statistically insignificant. Alternatively, Musharakah is positively and significantly related to Mudarabah. Musharakah and Mudarabah have a positive but insignificant relationship. The findings of this study suggest that management of partnership has a positive impact on firm partnership. Furthermore, it supports the hypothesis that improving partnership enhances Musharakah, which has a positive impact on the firm's partnership.

• Journal of radiological science and technology
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• v.1 no.1
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• pp.37-43
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• 1978

This Study was conducted, during the period of 8-16th, August in 1977 and 27th, January through 2, Feburury in 1978, to measure laking off and on time for patient's clothes at the radiologic department in general hospitals. The study dealt with three general hospitals which were classified into groups by ownerships; two university hospitals, one private hospitals. The scope of the study was limited to measurement's of taking off and on time except taking a radiograph. The results were summarized as follows: [1] In Summer, the average taking off ana on tine for male was 3 minutes and 7 seconds and 3 minutes and 43 seconds for female. The latter was longer than that for the former. [2] In Winter, the mean taking off and on time for male was 3 minutes 42 seconds, 4 minutes 17 seconds for female. [3] In this respect, the average taking off and on time for female was longer than that for male and that for winter was expended that for summer. [4] In Summer, regardless of age group and sex, the average taking off and on time for taking a radiograph was 3 minutes 25 seconds, and 3 minuteds 59 seconds in Winter. [5] Regardless of season, sen, and age, the mean time expended to take off and on for taking a radiograph was 3 minutes 43 seconds.

• International Journal of Industrial Entomology and Biomaterials
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• v.2 no.2
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• pp.149-153
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• 2001

The influence of baculovirus Bombyx mori Nuclear Polyhedrosis virus (BmNPV) infection on intermediary metabolic pathways in silkworm Bombyx mori L. was investigated. Studies revealed that NADP-linked malate dehydrogenase activity in hemolymph of infected silkworms at 96 hrs post infection (p.i.) with visible symptoms of infection was enhanced in comparison to healthy larvae of the same age. Also, NADP-dependent MDH activity was significantly lower in fat body cytosol of infected larvae at 96 hrs p.i. when compared to healthy larvae. Similarly, some biometabolic parameters like growth, protein content and cholesterol titer were observed to be influenced by baculovirus infection. While the growth of infected larvae was significantly retardedi protein content was also drastically reduced in both hemolymph and fat body tissues. Cholesterol titers however, was enhanced in infected larvae. The results observed herein point to a significant change in the normal biochemical and biometabolic pathways required for growth and development following BmNPV infection.

• Structural Monitoring and Maintenance
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• v.8 no.4
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• pp.379-402
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• 2021

Traditional approaches for structural health monitoring (SHM) seldom take ambient uncertainty (temperature, humidity, ambient vibration) into consideration, while their impacts on structural responses are substantial, leading to a possibility of raising false alarms. A few predictors model-based approaches deal with these uncertainties through complex numerical models running online, rendering the SHM approach to be compute-intensive, slow, and sometimes not practical. Also, with model-based approaches, the imperative need for a precise understanding of the structure often poses a problem for not so well understood complex systems. The present study employs a data-based approach coupled with Empirical mode decomposition (EMD) to correlate recorded response time histories under varying temperature conditions to corresponding damage scenarios. EMD decomposes the response signal into a finite set of intrinsic mode functions (IMFs). A two-dimensional Convolutional Neural Network (2DCNN) is further trained to associate these IMFs to the respective damage cases. The use of IMFs in place of raw signals helps to reduce the impact of sensor noise while preserving the essential spatio-temporal information less-sensitive to thermal effects and thereby stands as a better damage-sensitive feature than the raw signal itself. The proposed algorithm is numerically tested on a single span bridge under varying temperature conditions for different damage severities. The dynamic strain is recorded as the response since they are frame-invariant and cheaper to install. The proposed algorithm has been observed to be damage sensitive as well as sufficiently robust against measurement noise.

• The Plant Pathology Journal
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• v.27 no.2
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• pp.148-155
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• 2011

Our previous sequence and phylogenetic analyses of the Korean Rice stripe virus (RSV) suggested possible genetic reassortment of RNA segments, but whether this RNA variation contributed to the recent RSV outbreaks in Korea is yet unclear. To further clarify these RSV-RNA segment variations, we developed a reverse transcription-polymerase reaction/restriction enzyme (RT-PCR/RE) analysis-based method. We identified five REs, including DraI, EcoR1, NdeI/AseI, and SpeI, that could differentiate RSV RNA 1-4 subtypes, respectively. Our RT-PCR/RE results provided a clear pattern of RNA reassortment, i.e., different groups of isolates having their RNA segments derived from two to three different RSV ancestors, such as from Eastern and Southwestern Chinese or Japanese M and T isolates. We also found that the migratory small brown planthopper from Eastern China caught by aerial net traps that possesses RSV-RNA3 genotypes corresponds mainly to Eastern China, with a few for Southwestern China based on RT-PCR/RE, sequence and phylogenetic analyses, indicating that RSV populations in Eastern China may also have strong RNA variation. The development of an RE analysisbased method proved a useful epidemiological tool for rapid genotyping and identification of mixed infections by RSV strain and by different subtype.

• Wind and Structures
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• v.30 no.5
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• pp.525-532
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• 2020

This work numerically investigates the effects of Reynolds number Re_D (= 100 - 150), cross-sectional aspect ratio AR = ( 0.25 -1.0), and attack angle α (= 0° - 90°) on the forces, Strouhal number, and wake of an elliptical cylinder, where Re_D is based on the freestream velocity and cylinder cross-section height normal to the freestream flow, AR is the ratio of the minor axis to the major axis of the elliptical cylinder, and α is the angle between the cylinder major axis and the incoming flow. At Re_D = 100, two distinct wake structures are identified, namely 'Steady wake' (pattern I) and 'Karman wake followed by a steady wake (pattern II)' when AR and α are varied in the ranges specified. When Re_D is increased to 150, an additional wake pattern, 'Karman wake followed by secondary wake (pattern III)' materializes. Pattern I is characterized by two steady bubbles forming behind the cylinder. Pattern II features Karman vortex street immediately behind the cylinder, with the vortex street transmuting to two steady shear layers downstream. Inflection angle α_i = 32°, 37.5° and 45° are identified for AR = 0.25, 0.5 and 0.75, respectively, where the wake asymmetry is the greatest. The α_i effectively distinguishes the dependence on α and AR of force and vortex shedding frequency at either Re_D. In Pattern III, the Karman street forming behind the cylinder is modified to a secondary vortex street. At a given AR and α, Re_D = 150 renders higher fluctuating lift and Strouhal number than Re_D = 100.