• Title/Summary/Keyword: I-GPA

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Immune-enhancing effects of polysaccharides with different molecular weights obtained from Gloiopeltis furcata (불등풀가사리 다당류의 분자량에 따른 면역증강 효과)

  • Lee, Dae-Hoon;Hong, Joo-Heon
    • Food Science and Preservation
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    • v.25 no.1
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    • pp.1-6
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    • 2018
  • This study investigated the immune-enhancing effects of polysaccharides extracted from Gloiopeltis furcata (red seaweed) with different molecular weights. A crude polysaccharide mixture was hydrolyzed using acid treatment (0.1 N HCl) and three molecular weight fractions were generated and filtered using centrifugation: (${\leq}10kDa$, 10 to 100 kDa, and 100 kDa. Nitric oxide (NO) production in RAW264.7 cells treated with $0.01-0.5{\mu}g/mL$ polysaccharides ${\geq}100kDa$ was $12.28-19.05{\mu}M$. Treatment with polysaccharides ${\geq}100kDa$ increased cytokine levels, including TNF-${\alpha}$ and IL-6 levels, in a dose-dependent manner. Polymerase chain reaction analysis also revealed marked increases in iNOS and COX-2 mRNA expression levels. These findings lead us to conclude that macrophage activation induced by polysaccharides ${\geq}100kDa$ was greater than that induced by polysaccharides ${\leq}10kDa$ or between 10 and 100 kDa. The polysaccharides ${\geq}100kDa$ extracted from Gloiopeltis furcata investigated herein are potentially useful as natural immune-enhancing agents. These findings provided further insights into the potential use of ${\geq}100kDa$ as immunopotentiator or new function food.

Optimization of tetrahedral amorphous carbon (ta-C) film deposited with filtered cathodic vacuum arc through Taguchi robust design (다구찌 강건 설계를 통한 자장 여과 아크 소스로 증착된 사면체 비정질 탄소막의 최적화)

  • Kwak, Seung-Yun;Jang, Young-Jun;Ryu, Hojun;Kim, Jisoo;Kim, Jongkuk
    • Journal of the Korean institute of surface engineering
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    • v.54 no.2
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    • pp.53-61
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    • 2021
  • The properties of tetrahedral amorphous Carbon (ta-C) film can be determined by multiple parameters and comprehensive effects of those parameters during a deposition process with filtered cathodic vacuum arc (FCVA). In this study, Taguchi method was adopted to design the optimized FCVA deposition process of ta-C for improving deposition efficiency and mechanical properties of the deposited ta-C thin film. The influence and contribution of variables, such as arc current, substrate bias voltage, frequency, and duty cycle, on the properties of ta-C were investigated in terms of deposition efficiency and mechanical properties. It was revealed that the deposition rate was linearly increased following the increasing arc current (around 10 nm/min @ 60 A and 17 nm/min @ 100A). The hardness and ID/IG showed a correlation with substrate bias voltage (over 30 GPa @ 50 V and under 30 GPa @ 250 V). The scratch tests were conducted to specify the effect of each parameter on the resistance to plastic deformation of films. The analysis on variances showed that the arc current and substrate bias voltage were the most effective controlling parameters influencing properties of ta-C films. The optimized parameters were extracted for the target applications in various industrial fields.

Structural optimizations of the optical fiber hydrophones with the hollow mandrel: Part I. Effects of the foraming layer on the wave propagation and the sensitivity (중공형 멘드릴을 이용한 광섬유 하이드로폰의 최적 구조 설계 Part I. Forming 층이 음파 전달 및 감도에 미치는 영향)

  • 임종인;노용래
    • The Journal of the Acoustical Society of Korea
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    • v.17 no.4
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    • pp.23-29
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    • 1998
  • 본 논문은 foraming층이 음파의 전달 특성에 미치는 영향 및 멘드릴형 광섬유 하이 드로폰의 광음향 감도 특성에 미치는 영향을 분석한 것이다. 유한 요소법을 이용하여 foaming층의 내부 구조에 따른 음파의 전달 특성을 분석하였고, AL(Aluminium)/foaming 및 Nylon/foaming 멘드릴(mandrel) 각각에 대하여 foaming층의 재질 및 두께 변화에 따른 광음향감도 변화를 분석하였다. 그 결과, foaming층 내의 구조변화의 영향을 무시할 수 있 었다. 또한 AL al cNylon층상 복합체인 멘드릴에서 foaming층의 탄성율이 낮을수록, 두께 가 증가할수록 공음향 감도는 증가하였다. 그러므로 1GPa 이하의 탄성율을 지닌 두꺼운 Foaming층을 사용하여 층상 복합체 멘드릴을 구성하는 것이 광음향 감도의 향상을 위하여 효율적이다.

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Control of Microstructures and Properties of Composites of the Al2O3/ZrO2-ZrO2-Spinel System: I. Preparation and Sintering Behavior of Al2O3-ZrO2 Composite Powders (Al2O3/ZrO2-Spinel계 복합체의 미세구조 및 물성제어: I. Al2O3-ZrO2 복합분체의 제조 및 소결특성)

  • 현상훈;송원선
    • Journal of the Korean Ceramic Society
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    • v.29 no.10
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    • pp.797-805
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    • 1992
  • Al2O3-20 wt% ZrO2 composite powders to be used as the starting materials of the Al2O3/ZrO2-Spinel composite system were prepared by the use of the emulsion-hot kerosene drying method. The crystalline phase of ZrO2 in the synthesized Al2O3-ZrO2 composite powders was 100% tetragonal but the small amount of t-ZrO2 was transformed into m-ZrO2 after crushing. The hardness, fracture toughness, and flexural strength of the composite, which was sintered at 1650$^{\circ}C$ for 4 hrs after calcining at 1100$^{\circ}C$ for 2 hrs and had the relative density of 99%, were 15.7 GPa, 4.97 MN/m3/2, and 390 MPa, respectively. The fracture form in the sintered composites was found to be the intergranular fracture.

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Evaluation of Mechanical Properties and Microstructural Behavior of Sintered WC-7.5wt%Co and WC-12wt%Co Cemented Carbides

  • Raihanuzzaman, Rumman Md.;Song, Jun-U;Tak, Byeong-Jin;Hong, Hyeon-Seon;Hong, Sun-Jik
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2011.05a
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    • pp.58.1-58.1
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    • 2011
  • WC-Co and other similar cemented carbides have been widely used as hard materials in industrial cutting tools and as mould metals; and a number of techniques have been applied to improve its microstructural characteristics, hardness and ear resistance. Cobalt is used primarily to facilitate liquid phase sintering and acts as a matrix, i.e. a cementing phase between WC grains. A uniform distribution of metal phase in a ceramic is beneficial for improved mechanical properties of the composite. WC-Co, starting from initial powders, is vastly used for a variety of machining, cutting, drilling, and other applications because of its unique combination of high strength, high hardness, high toughness, and moderate modulus of elasticity, especially with fine grained WC and finely distributed cobalt. In this study, that started with two different compositions of initial powders, WC-7.5wt%Co and WC-12wt%Co with initial powder size being 1~3 ${\mu}m$, magnetic pulsed compaction followed by subsequent vacuum sintering were carried out to produce consolidated preforms. Magnetic Pulsed Compaction (MPC), a very short duration (~600 ${\mu}s$), high pressure (~4 Gpa), high-density preform molding method was used with varied pressure between 0.5 and 3.0 Gpa, in order to reach an initial high density that would help improve the sintering behavior. For both compositions and varied MPC pressure, before and after sintering, changes in microstructural behavior and mechanical properties were analyzed. With proper combination of MPC pressure and sintering, samples were obtained with better mechanical properties, densification and microstructural behavior, and considerably improved than other conventional processes.

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System Development and Management for Underachieved Students (자존감 향상 프로그램 개발 및 운영사례)

  • Kim, Young-Jun;Kim, Hee-Kyo;Oh, Kyeong-seok
    • Journal of the Korea Convergence Society
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    • v.9 no.6
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    • pp.183-190
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    • 2018
  • With decreasing the number of high school graduates, it is vital for each college to maintain its enrollment number as well as to preserve its dropout rate in a lower level. It is true that all universities and colleges have experienced inevitable dropouts that were in fact more serious in 2 to 3-year colleges. There have been prior studies to examine what factors affected to students' dropout in various ways. However, no specific programs were employed to mitigate the rates of dropout. In this study, new encouraging program is introduced for the students who were not ready to study and isolated from classroom. The result showed that the program led to the GPA enhancement in larger number of participants. Nevertheless, the sustainablity of the program would be unclear unless it combines with other existing programs.

Tensile Stress Measurement of Tendon with Wiedemann Effect (Wiedemann 효과를 이용한 텐던의 인장력 측정)

  • Kang, Sunju;Son, Derac;Joh, Changbin;Lee, Jungwoo
    • Journal of the Korean Magnetics Society
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    • v.26 no.4
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    • pp.133-136
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    • 2016
  • In this study, we have constructed a measuring system to investigate tensile stress of tendons, which is employed in bridges, by means of the magnetic non-destructive testing (NDT) method. For the twisted 7-strands tendon, we have used Wiedemann effect. An ac current was applied to the tendon and voltage induced from Search Coil on Tendon (SCT) under applying tensile stress was measured. The measuring system consists of tensile stress applying apparatus up to 2 GPa, and ac current supply to apply current to the tendon directly to magnetize the tendon. We have invested two kinds of tendon which were produced by different companies for testing with constructed measuring system. Voltage induced from SCT was decreased up to 1.5 GPa linearly and two kinds of tendon which were produced by different companies shows similar trends. Thus, Wiedemann effect was also applicable to measure tensile stress of tendon by means of magnetic NDT.

Multifunctionality in Ceramic/Metal Nanocomposites

  • Sekino, Tohru;Kondo, Hiroki;Niihara, Koichi
    • Journal of Powder Materials
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    • v.8 no.3
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    • pp.186-191
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    • 2001
  • Several fabrication processes, corresponding nanostructural features and multifunctionality as well has been investigated for oxide ceramic based nanocomposites with metal nanodispersion (i.e., ceramic/metal nanocomposites). Transition metal (Ni, Co, etc) dispersed alumina and zirconia based nanocomposites have been synthesized by reducing and hot-press sintering of ceramic and metal oxide mixtures prepared by several method. Improved fracture strength (1.1 and 1.9 GPa for $Al_2O_3/Ni$ and $ZrO_2/Ni$ nanocomposites, respectively) of these composites have been achieved according to their nanostructures. In addition, ferromagnetic characteristic has been kept. The variation of magnetization with an applied stress has found to be more sensitive as smaller as the magnetic metal dispersion is. This result thus suggests the possibility of fracture and/or stress sensing of the composites by simple magnetic measurement.

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GPA(Grade Point Average) Achievement Level By Ability Grouping Calculus Courses (대학수학의 수준별 수업에 따른 학업성취도 분석)

  • Kim, Tae-Soo;Kim, Byoung-Soo
    • Communications of Mathematical Education
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    • v.22 no.3
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    • pp.369-382
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    • 2008
  • We discuss the effect of ability grouping calculus courses based upon student's proficiency of the subject and their collective examination of midterms and finals among mid-level and low-level classes. We assess incoming freshmen at Seoul National University of Technology(SNUT) of their proficiency in calculus and assign them to the appropriate levels within the course(i.e., high-level, mid-level, low-level). We found that this was beneficial to both students and instructors. Instructors can easily determine the pace in which each class should be kept, and students can quickly adapt to the learning environment.

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Dynamic Deformation Behavior of Zr-Based Bulk Amorphous Alloy after Annealing Treatments (벌크형 비정질 Zr계 합금의 결정화 열처리에 따른 동적변형 거동)

  • Chang J. J;Lee B. J;Hwang J. I;Park I. M;Cho K. M;Cho Y. R
    • Korean Journal of Materials Research
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    • v.14 no.3
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    • pp.181-185
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    • 2004
  • The mechanical properties of a bulk amorphous alloy ($Zr_{41.2}$ $Ti_{13.8}$ /$Cu_{10}$ $Ni_{10}$ $Be_{22.5}$ /at.%) before and after an annealing treatment were investigated. For the bulk amorphous alloy, the compressive strength was about 2.0 GPa, irrespective of the strain rates in the range of $10^{-4}$ to $10^3$$ sec^{-1}$ . Fine-sized nanocrystalline particles (10~100 nm) were precipitated homogeneously in the bulk amorphous matrix after the annealing treatments. Compared to the bulk amorphous materials, these composite materials, composed of the nanocrystalline phases and a bulk amorphous matrix had much different mechanical properties. The strength and strain of coposite materials measured by a compressive test showed a peak-maximum values at 7 vol.% of the nanocrystalline phases. The values in higher volume fraction of the crystalline phases in the amorphous matrix were decreased, as measured by both quasi-static and high strain rate. The decrease in fracture strength is due to presence of the dispersed large-crystalline phases in the amorphous matrix.