• Title/Summary/Keyword: Hydro power

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A Study on the Modeling Analysis for Kaplan Micro-turbines (케프란 마이크로터빈의 모델링 해석에 관한 연구)

  • Kim, O.S.;Kim, I.S.;Kim, H.H.;Shim, J.Y.
    • Journal of Power System Engineering
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    • v.10 no.4
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    • pp.105-110
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    • 2006

  • Among many other alternative energy resources, small scale hydro power has been brought into attention as a reliable source of energy today, which had been relatively neglected since 1960s. Especially, Kaplan micro-turbine can be applied to various kind of small hydro power plants, such as reservoirs for agriculture purpose, sewage treatment plants and water purification plants. However present low head of Kaplan micro-turbines and small scale hydro turbines, have limitations in the minimum required head and flow rate for efficient operation. This research is to develop modeling analysis for the Kaplan micro-turbine, which can improve economical features of small hydro power plants. The contents and scope of this research are the efficiency improvement of Kaplan micro-turbine.

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The potential impact of low dose ionizing ${\gamma}$-radiation on immune response activity up-regulated by Ikaros in IM-9 B lymphocytes

  • Kim, Sung-Jin;Jang, Seon-A;Yang, Kwang-Hee;Kim, Ji-Young;Kim, Cha-Soon;Nam, Seon-Young;Jeong, Mee-Seon;Jin, Young-Woo
    • 대한방사선방어학회:학술대회논문집
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    • 2011.11a
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    • pp.212-213
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    • 2011

  • The biological effects of low dose ionizing radiation (LDIR) remain insufficiently understood. We examined for the scientific evidence to show the biological effects of LDIR using radiation-sensitive immune cells. We found that Ikaros protein was responsed to low dose-dependent effects of gamma radiation in IM-9 B lymphocytes. Ikaros encodes zinc finger transcription factors that is important regulators of a hematopoietic stem cells (HSCs) progression to the B lymphoid lineage development, differentiation and proliferation. In this study, we observed that cell proliferation was enhanced from 10% to 20% by LDIR (0.05 Gy) in IM-9 B lymphocytes. The Ikaros protein was phosphorylated in its serine/threonine (S/T) region and decreased its DNA binding activity in the cells exposed to LDIR. We found that Ikaros phosphorylation was up-regulated by CK2/AKT pathway and the residues of ser-304 and ser-306 in Ikaros was phosphorylated by LDIR. We also observed that Ikaros protein was localized from the nucleus to the cytoplasm after LDIR and bound with Autotaxin (ENPP2, ATX) protein, stimulating proliferation, migration and survival of immune cells. In addition, we found that the lysoPLD activity of ATX was dependent on Ikaros-ATX binding activity. These results indicate that the Ikaros is an important regulator of immune activation. Therefore, we suggest that low dose ionizing radiation can be considered as a beneficial effects, stimulating the activation of immune cells.

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