• Journal of the Korean Chemical Society
• /
• v.35 no.2
• /
• pp.142-150
• /
• 1991

The complexation of hydrazide schiff base ligands such as N,N'-oxalylbis(salicylaldehyde hydrazone), N,N'-malonylbis(salicylaldehyde hydrazone), and N,N'-succinylbis(salicylaldehyde hydrazone) with Cd(II) ion was studied by polarographic method in DMSO solution. The order of stability constants was OBSH < MBSH < SBSH, and these ligands formed stable complexes with Cd(II) ion. The stability constants of complexation were measured at various temperatures. As the results, ${\Delta}$H and ${\Delta}$S of the complexation were distributed on the complex stabilities.

• Journal of the Korean Chemical Society
• /
• v.35 no.2
• /
• pp.135-141
• /
• 1991

The complexation of N,N'-oxalylbis(salicylaldehyde hydrazone) (OBSH) with Zn (II), Cd (II), and Pb(II) ions was studied by polarographic method in DMSO solution. The order of stability constants was Cd(II) < Zn(II) < pb(II), and all heavy metal ions formed stable complex with OBSH ligand. The stability constants of complexation were measured at various temperatures. As the results, enthalpy and entropy changes of the complexation were distributed on the complex stabilities.

• Archives of Pharmacal Research
• /
• v.14 no.3
• /
• pp.237-241
• /
• 1991

The tautomerism in 3-phenyl-4-arylazo-5-isoxazolones 1 was examined by $^1H-NMR$ spectra of $^15N-labeled$ compound and by HMO method. Both spectra data $(^1H-NMR\;and\;IR)$ and bonding energies are in support of the assignment of the hydrazone structure to such compounds. It is further shown that intermolecular and intramolecular hydrogen bondings favor the hydrazone tautomer.

• Bulletin of the Korean Chemical Society
• /
• v.27 no.2
• /
• pp.185-186
• /
• 2006

• Journal of the Korean Chemical Society
• /
• v.36 no.1
• /
• pp.95-99
• /
• 1992

A spectrophotometric method for the determination of copper using N,N'-Oxalylbis(salicylaldehyde hydrazone) as a chromogenic reagent has been developed. Determination has been performed by measuring the absorbances of the copper complexes in solutions containing 60% dimethylformamide (pH 2) at 422 nm. The method allows the determination of 0.4${\sim}$1.8 ${\mu}$g/ml of copper and has been applied to its determination in synthetic mixtures and alloy samples.

• Journal of the Korean Chemical Society
• /
• v.53 no.1
• /
• pp.34-41
• /
• 2009

A new series of hydrazone derivatives were synthesized from 4-(2-chloroethyl)semicarbazide and their antiproliferative activity against human brain (U251) and liver (Hepg2) carcinoma cell lines were evaluated. The hydrazone compounds are benzaldehyde (2a-2g), acetophenone (3a-3f), and 3-formylindole derivatives (4a-4d). Among the acetophenone derivatives, 3e (p-methoxy substituted) and 3f (p-nitro substituted) showed the highest cytotoxic activity against Hepg2 cell line (I$C_{50}$ = 6 and 8 $\mu$g/ml, respectively). Among the 3-formylindole derivatives, 4a (hydrazone of 3-formylindole itself) showed a pronounced cytotoxic activity against both U251 (I$C_{50}$ = 21 $\mu$g/ml) and Hepg2 (I$C_{50}$ = 7 $\mu$g/ml).

• Analytical Science and Technology
• /
• v.8 no.4
• /
• pp.469-475
• /
• 1995

Di-2-pyridylmethanon 2-thiophenecarboxylie hydrazone(DPMTCH) was synthesized and used as a chromogenic reagent in the spectrophotometric determination of nickel in steel. The proton disc spectrophotometrically, were $pK_{a1}= 2.66$ and $pK_{a2}= 10.98$ ${\mu}=0.5(NaCl)$. Nickel(II) reacts with DPMTCH to form a 1:2 metal-2-ligand ratio complex, the xylene solution of which has an absorption maximum at 417 nm. Beer's law is obeyed over the range $0-1.17\;mg\;ml^{-1}$ of nickel(II). The molar absorptivity of the nickel(II) complex is $4.17{\times}10^4l\;mol^{-1}\;cm^{-1}$. The precision of the method was estimated for 4.7 mg of nickel(II), the coefficient of variation for 15 replicate determinations being 0.34%.

• Korean Journal of Materials Research
• /
• v.13 no.8
• /
• pp.514-518
• /
• 2003

As a fundamental study on organic electroluminescence(EL), blue emitting materials were synthesized and characterized. Individual blue colored hydrazone derivatives were synthesized from the reaction of aldehydes (phthalaldehyde, isophthalaldehyde) with the corresponding amnios (1-methyl -1-phenylhydrazine, 1,1-diphenylhydrazine hydrochloride). Recrystallization of hydrazones from chloroform revealed the melting temperature within $142∼156^{\circ}C$. Photoluminescence(PL) analysis on each hydrazone showed that emission range were blue(458∼478 nm). The structure of obtained hydrazones were elucidated by FT-IR, $^1$H-NMR and C, H, N elemental analyzer.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2022.11a
• /
• pp.73-74
• /
• 2022

The corrosion inhibitive effect of a new hydrazone-based heterocyclic compound for steel in simulated concrete pore solution with 3.5 wt.% sodium chloride was investigated by experimental and computational techniques. Electrochemical studies, up to 30 days of immersion, and surface analysis (X-ray photoelectron spectroscopy (XPS), atomic force microscopy (AFM), and scanning electron microscope (SEM)) were performed to assess the corrosion protection abilities of investigated compound for steel rebar. Results showed that adding the organic compound to the chloride contaminated concrete pore solution decreased the corrosion rate of the steel rebar thanks to the effective adsorption of inhibitor molecules. After 30 days of immersion of steel rebar in inhibited chloride contaminated synthetic concrete pore solution, the inhibition efficiency exceeded 80% at low concentration of 1 mmol/L. Computational studies by Density Functional based Tight Binding (DFTB) method revealed the formation of covalent bonds between the hydrazone molecule and the iron surface.

• Bulletin of the Korean Chemical Society
• /
• v.20 no.7
• /
• pp.771-772
• /
• 1999