• Journal of the Korea Institute of Building Construction
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• v.17 no.6
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• pp.527-534
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• 2017

Accordingly, this study, in order to use powder of recycled aggregate from production of recycled aggregate as an activator of ground granulated blast furnace slag, the influence of added recycled aggregate powder on physical properties of concrete induced ground granulated blast furnace slag were analyzed by hydration stages. The results of the study are summarized as follows: Except for samples eluted powder of recycled aggregate 1%, all the samples were high alkali suspensions with higher than pH 12.0. In particular, when eluted time was 5 hours, the sample eluted powder of recycled aggregate 3% showed about 15 mg/l of calcium hydroxide that was not different from the amount of calcium hydroxide in the mixing water eluted powder of recycled aggregate 5%. Hence, from this results, it can be considered that optimal eluted powder of recycled aggregate was 3% in this study. When using mixing water eluted with powder of recycled aggregate, compared to use of ordinary mixing water, it showed greater compressive strength in the entire ages, and in the sample replaced with ground granulated blast furnace slag by 50%, its compressive strength was greater than that of the OPC. As use of mixing water eluted with powder of recycled aggregate in concrete used with large amount of ground granulated blast furnace slag was more effective for improving compressive strength than ordinary mixing water, it is verified that powder of recycled aggregate had an effect of activator.

• Journal of the Korea Concrete Institute
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• v.15 no.1
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• pp.43-51
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• 2003

Recently, to consider financial and constructive aspect usage of Admixture such as Blast-Furnace Slag and Fly-Ash, are increased. Also the use of cold-weather-concrete is increased. Blast-Furnace Slag, a by-product of steel industry, have many advantage to reduce the heat of hydration, increase in ultimate strength and etc. But it also reduces early-age strength, so it is prevented from using of Blast-Furnace Slag at cold-weather-concrete. In this study, for the purpose of increasing usage of Blast-Furnace Slag at cold-weather-concrete, it is investigated the strength properties of concrete subjected to frost damage for the cause of early age curing. The factors of this experience to give early frost damaged were Freezing temperature(-1, -10, $-15^{\circ}C$), Early curing age(0, 12, 24, 48hour), Freezing times(0, 12, 24, 48hour). According to this study, if early curing is carried out before haying frost damage, the strength of concrete used admixture, subjected to frost damage, is recovered. And that properties are considered, the effect of using admixture like blast-furnace-slag, is very high

• Journal of the Korea Concrete Institute
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• v.26 no.2
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• pp.117-124
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• 2014

Globally, there are environmental problems due to greenhouse gas emissions. $CO_2$ emissions rate of the cement industry is very high, but the continued demand of cement is needed in the future. In this study, in order to reduce the environmental impact of $CO_2$ emissions from cement production. The experiments were carried out for the development of non-sintered cement (have not undergone firing burning) by granulated ground blast furnace slag. In order to compare the characteristics by curing, an experiment was conducted by changing the curing conditions such as atmospheric steam curing, observe the mechanical properties for the measurement of flexural compressive strength by mortar, observe the chemical properties such as acid resistance, $Cl^-$ penetrate resistance and analyzed the mechanism of hydration by XRD, SEM experiments. From the experimental results, as compared with portland cement usually confirm the mechanical and chemical properties excellent, it is expected be possible to apply to the undersea, underwater and underground structures that require superior durability. In addition, based on the excellent compressive strength by steam curing, it is expected to be possible to utilize as a cement replacement material in the secondary product of concrete. In the future, to solve the problem through continued research, it will be expected to reduce the effect of environmental load and to be excellent economics.

• The Korean Journal of Nuclear Medicine
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• v.23 no.1
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• pp.55-61
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• 1989

While cisplatin has been widely used in the treatment of a variety of cancers, nephrotoxicity is one of the major problems which frequently limit clinical usefulness of cisplatin. This study has been conducted to investigate nephrotoxicity of cisplatin in terms of changes in glomerular filtration rate (GFR) and effective renal plasma flow (EFPF) measured by the simultaneous use of $^{99m}Tc-DTPA$ and $^{131}I-OIH$, before and after administration of cisplatin, in 12 patients with lung cancer and four patients with esophageal cancer. Cisplatin was administrated at total doses of $75\sim100mg/m^2$ with two hour hydration and diuresis method. GFR determined by the use of $^{99m}Tc-DTPA$ had a good correlation with 24-hour creatinine clearance rate (r=0.77, p<0.001). GFR and filtration fraction decreased immediately after administration of cisplatin, however, they showed a tendency to be in completely recovered four weeks after administration. ERPF was not changed immediately after and four weeks after administration of cisplatin. GFR before and immediately after administration of cisplatin were analyzed with regard to age, sex, performance status, previous adminstration of cisplatin and method of administration. None of these factors had any influence on the rate of decrease in GFR except method of administration. Administration of cisplatin as a single dose lowered GFR more compared with that as divided doses. In this study, we have also demonstrated that the simultaneous use of $^{99m}Tc-DTPA$ and $^{131}I-OIH$ was a useful tool for the measurement of GFR and ERPF respectively.

• Korean Journal of Food Science and Technology
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• v.52 no.5
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• pp.467-475
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• 2020

Ultraviolet radiation is a major cause of photoaging, characterized by wrinkle formation and skin dehydration. Mojaban (Sargassum fulvellum), belonging to the brown algae of the Sargassaceae family, exerts anti-inflammatory, antioxidant, and anti-atopic activities. Particularly, Mojaban extract alleviated ultraviolet B (UVB)-induced inflammatory responses in human keratinocytes and BALB/c mice. Here, the dorsal skin of hairless mice was exposed to UVB for photoaging. The mice were administrated 300 mg/kg Mojaban extract (S. fulvellum extract; SFE) daily. Phenotypically, SFE reduced wrinkle formation and epidermal thickness and increased skin elasticity. SFE increased hydroxyproline content by upregulating the expression of collagen-related genes and downregulating matrix metalloproteinase expression. Furthermore, SFE increased skin moisture content and inhibited transepidermal water loss. SFE upregulated the expression of involucrin, loricrin, and transglutaminase for cornified envelope formation as well as the expression of filaggrin and caspase-14 for natural moisturizing factors. Collectively, SFE may be employed as a nutraceutical ingredient for anti-photoaging.

• Journal of the Korea Concrete Institute
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• v.17 no.1 s.85
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• pp.95-104
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• 2005

The research conducted to study the potential practicability of recycled aggregate concrete by analyzing the characteristics of concretes made of recycled quality aggregates produced by wet and dry process has found the following results. The air content of recycled aggregate concrete increased with increase of the substitut on rate due to mortar included while producing recycled aggregates. However, the concretes with aggregate produced by dry process had relatively low rate of increase in air content. The slump showed generally decreasing trend as the substitution rate of recycled aggregate increased regardless of the wet or dry process. It was assumed that the mortar particles remained in recycled aggregate absorbed the surplus hydration in concrete and decreased fluidity The compressive strength generally decreased as the substitution rate of recycled aggregate increased, however there was an increasing trend as well due to decreasing effect of water-cement ratio when the substitution rate of recycled aggregate reached 25, 50% after mix. This phenomena also appeared in early age, which meant that recycled aggregate concrete should not be retarded in setting when applied in the field. The tensile strength also reached the maximum when wet or dry recycled aggregate replaced with 25%. To conclude, recycled aggregates for concrete produced by wet or dry process are expected to demonstrate essential characteristics of concrete without significant decline in physical or dynamic quality when the substitution rate is below 25% although there are variations subject to water-cement ratio. However, slight differences are expected due to types of recycled aggregate and physical quality.

• Korean Journal of Food Science and Technology
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• v.36 no.3
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• pp.490-500
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• 2004

Brown rice grains were coated by spraying aqueous protein solution extracted from rice bran using 10% ethanol, and dried at room temperature. Coating procedure was repeated 1-5 times to determine effect of repeated coating, Quality changes in coated brown rice grains were observed during 8 weeks storage. Most coated rice grains gave lower peroxide and acid values, which indicate antioxidative effects of coating. Lipase and lipoxygenase activities generally decreased in grains coated more than three times. Microscopic images of whole kernel and longitudinal section revealed cracking on all brown rice grains including control, and hydration rate constants were not significantly different among treated grains. Compared to non-coated brown rice grains, those coated more than three times, after 8 week storage, showed better quality retention observed in (meaning not clear) higher water-binding capacity, lower gel consistency decrease, less browning, and better textural properties in cooked rice, resulting in better sensory quality.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.2
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• pp.689-696
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• 2017

The practical applications of ordinary high-fluidity concrete have been limited due to several drawbacks, such as high hydration heat, high amount of shrinkage, and non-economic strength development. On the other hand, due to its advantages, such as improvement of construction quality, reduction of construction cost and period, the development of high-fluidity concrete is a pressing need. This study examined the properties of high-fluidity concrete, which can be manufactured on the low binders using a viscosity agent to prevent the segregation of materials. The optimal viscosity agent was selected by an evaluation of the mechanical properties of high-fluidity concrete among six viscosity agents. The acrylic type and urethane type viscosity agents showed the best performance within the range where no material separation occurred. The mechanical properties were evaluated to examine the optimal amount of AC and UT viscosity agent added by mixing two viscosity agents according to the adding ratio and blending them together with high performance water reducing agent. When the ratio of the AC : UT viscosity agents was 5:5, it was most suited for high-fluidity concrete with low binders by increasing the workability and effect of the reducing viscosity.

• International Journal of Highway Engineering
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• v.6 no.4 s.22
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• pp.75-89
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• 2004

Long term performance of concrete pavement significantly depends on the given construction and environmental condition. It means that random cracks and extreme crack width due to inappropriate quality control at the early age might lead to decreasing the pavement service life. The temperature and moisture during the construction, cement and aggregate types, curing condition are major components to affect the quality of the concrete pavement at the early age. First of all, the high temperature differential, that is made by increasing air temperature and the heat of cement hydration, is known as the major contributor to severe cracks. In this study, tent covering was used for controlling temperature of the concrete slab. The field measurement data indicates that the effect of the tent covering is very significant to decrease possibilities of random crack occurrence and curling stress and enhance the long-term concrete strength. HIPERPAV(High PERformance PAVing software), a program predicting the strength and stress of an earty-age concrete pavement (72 hour after placement), is used for simulating the effects of tent covering. The HIPERPAVE results showed that the section with the tent covering has higher reliability than the section without the tent covering by 22.5%. In details, reliability is increased 72.5% (without the tent covering) to 95% (with the tent covering).

• Journal of Ginseng Research
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• v.44 no.6
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• pp.799-807
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• 2020

Background: The skin acts as a barrier to protect organisms against harmful exogenous agents. Compound K (CK) is an active metabolite of ginsenoside Rb1, Rb2 and Rc, and researchers have focused on its skin protective efficacy. In this study, we hypothesized that increased expression of the serine protease inhibitor Kazal type-5 (SPINK5) may improve skin barrier function. Methods: We screened several ginsenosides to increase SPINK5 gene promoter activity using a transactivation assay and found that CK can increase SPINK5 expression. To investigate the protective effect of CK on the skin barrier, RT-PCR and Western blotting were performed to investigate the expression levels of SPINK5, kallikrein 5 (KLK5), KLK7 and PAR2 in UVB-irradiated HaCaT cells. Measurement of transepidermal water loss (TEWL) and histological changes associated with the skin barrier were performed in a UVB-irradiated mouse model and a 1-chloro-2,4-dinitrobenzene (DNCB)-induced atopic dermatitis-like model. Results: CK treatment increased the expression of SPINK5 and decreased the expression of its downstream genes, such as KLKs and PAR2. In the UVB-irradiated mouse model and the DNCB-induced atopic dermatitis model, CK restored increased TEWL and decreased hydration and epidermal hyperplasia. In addition, CK normalized the reduced SPINK5 expression caused by UVB or DNCB, thereby restoring the expression of the proteins involved in desquamation to a level similar to normal. Conclusions: Our data showed that CK contributes to improving skin-barrier function in UVB-irradiated and DNCB-induced atopic dermatitis-like models through SPINK5. These results suggest that therapeutic attempts with CK might be useful in treating barrier-disrupted diseases.