• Archives of Craniofacial Surgery
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• v.13 no.2
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• pp.104-110
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• 2012

Purpose: Who may dare to state that optimal choice of treating nasal bone fracture is closed reduction? Few decades of authors' experience in nasal bone fracture has lead to believe that more active and assertive approach in nasal bone fracture by performing simultaneous lateral osteotomy may be applied in proper indications to acquire more accurate reduction and cosmetically satisfying result. Methods: From May 2008 to October 2009, among 241 nasal bone fracture patients, 20 patients underwent simultaneous lateral osteotomy with nasal bone fracture reduction. Followed by rigid septal correction, nasal cavity is packed to stabilize the fracture segment for safer osteotomy. Through intranasal incision, in selected cases of difficult reduction or for cosmetic purposes, various types of lateral osteotomy was performed corresponding to the fracture anatomy, conditions of the nasal cavity. Postoperative nasal packing was retained for one week and nasal dorsum splint for 3 weeks. Results: Lateral osteotomy was utilized for difficult cases of closed reduction, for correction of wide nose, hump and deviation in 9, 5, 2, and 4 cases, respectively. Patient satisfaction was scaled 90% in satisfaction and moderate in 10% (2 cases), complaining of mild nasal tip deviation. Physicians detected 2 cases of apparent deformity with patient recognition; one patient with mild step deformity at the osteotomy site and the other patient with minimal implant mobility. Conclusion: By accompanying profound understanding of the fracture anatomy, more active and assertive approach in nasal fracture reduction can be coincide with simultaneous lateral osteotomy to reduce the rate of secondary deformity and to obtain more cosmetically satisfying result.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.50 no.6
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• pp.799-805
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• 2017

The whistle sounds of three Beluga whales Delphinapterus leucas were recorded four times, for an hour each time, in 2016 and analyzed to obtain the most stable and basic acoustic characteristics of the whales in captivity. This study investigated the whistle characteristics of beluga whales and the relationship between whistle sounds and behavior to understand the meaning of the whistle sounds. The whistles were classified into six types (flat, ascending, descending, hump, dip, and wavy type) by their frequency contour and shape. The most common type was the ascending type, accounting for>30% of total whistles. The fundamental frequency of whistles was 2.0-8.6 kHz. Four types of behavior were related with the sounds of beluga whales (aggressive, submissive, affiliative, sexual behavior). A flat whistle was the most recorded in the group and an aggressive act was observed in association with the flat whistle. A dip whistle were recorded more when submissive acts were observed.

• International Journal of Fluid Machinery and Systems
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• v.10 no.3
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• pp.240-253
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• 2017

Latin hypercube sampling is widely used design-of-experiment technique to select design points for simulation which are then used to construct a surrogate model. The exploration/exploitation properties of surrogate models depend on the size and distribution of design points in the chosen design space. The present study aimed at evaluating the performance characteristics of various surrogate models depending on the Latin hypercube sampling (LHS) procedure (sample size and spatial distribution) for a diverse set of optimization problems. The analysis was carried out for two types of problems: (1) thermal-fluid design problems (optimizations of convergent-divergent micromixer coupled with pulsatile flow and boot-shaped ribs), and (2) analytical test functions (six-hump camel back, Branin-Hoo, Hartman 3, and Hartman 6 functions). The three surrogate models, namely, response surface approximation, Kriging, and radial basis neural networks were tested. The important findings are illustrated using Box-plots. The surrogate models were analyzed in terms of global exploration (accuracy over the domain space) and local exploitation (ease of finding the global optimum point). Radial basis neural networks showed the best overall performance in global exploration characteristics as well as tendency to find the approximate optimal solution for the majority of tested problems. To build a surrogate model, it is recommended to use an initial sample size equal to 15 times the number of design variables. The study will provide useful guidelines on the effect of initial sample size and distribution on surrogate construction and subsequent optimization using LHS sampling plan.

• Childhood Kidney Diseases
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• v.7 no.1
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• pp.67-72
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• 2003

Alport syndrome is the most common type of hereditary nephritis, and acute poststreptococcal glomerulonephritis(APSGN) is a common disease in children. We experienced the clinical and pathologic findings of Alport syndrome and APSGN in brothers of one family. Both patients presented with heavy gross hematuria and proteinuria. ASO titer was elevated in both cases, and the C3 level was reduced in one of the cases. In renal pathology, both showed characteristics of Alport syndrome as well as the glomerular changes of APSGN with hump-like subepithelial deposits by electron microscopy. These clinical observation indicated that the patients had APSGN superimposed on Alport syndrome, and that the episode of APSGN might exacerbate the clinical course of Alport syndrome.

• Archives of Pharmacal Research
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• v.28 no.5
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• pp.619-625
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• 2005

Beads loaded with the water-soluble drug, phenylpropanolamine HCl (PPA), were prepared using an extruder and double arm counter-rotating roller modified from a traditional pill machine. The mean diameter of the cylindrical rod-like extrudate from the ram extruder was 3 mm; that of the uncoated bead after cutting and spheronization by the modified double arm counter-rotating roller was 3.26~3.28 mm. Although the surface of the beads was moderately rough and irregular, some exhibited hump-shaped protrusions, the sphericity was acceptable (roundness 1.15) and adequate for the subsequent coating process. An increase in mean diameter of the coated beads and improvements in friability and sphericity were observed in proportion to the amount of coating material applied (ethylcellulose or Eudragit？？ RS 100). It was also found that the release rate of PPA from the coated beads could be controlled by the amount and type of coating materials applied or with the incorporation of Eudragit ？？ RS 100 into the core matrix. Further modifications to the double arm counter-rotating roller, including adjustment of the rotation speed and distance between the rollers, would yield smaller uncoated beads with improved roundness and surface roughness. In conclusion , the present method could be potentially applied to prepare controlled release drug delivery beads or pellet dosage forms.

• Transactions of the KSME C: Technology and Education
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• v.3 no.1
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• pp.1-13
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• 2015

In this study, a new dynamic VRF-type heat pump simulation model is proposed which incorporates frosting and defrosting models. Toward this end, a simple frosting model based on the perfect analogy, and lumped system based defrost model, are proposed. Then, frosting and defrosting models are incorporated into a dynamic heat pump model which adopts segment-by-segment local heat exchanger model and map-based variable speed compressor model. Thus, the model can naturally represent locally uneven frosting and defrosting on the heat exchanger surface. Developed simulation model is validated against available experimental data to show good agreement within 10% error for capacity and COP. Finally, developed dynamic heat pump model is applied to annual heating season simulation to show that seasonal COP of heat pump is degraded by 7% due to frosting and defrosting.

• Journal of Korean Society of Transportation
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• v.23 no.1
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• pp.33-44
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• 2005

Railroad crossing crashes are fewer than road crashes, but with regard to crash severity, they can be serious injury crashes. There should be, therefore, enormous efforts to increase the safety of railroad crossings. The objective of this paper is to identify and understand factors associated with railroad crossing crashes. Statistical models are used to examine the relationships between crossing accidents and geometric elements of crossings. The results show the Poisson model is the most appropriate method for the crossing accidents, because overdispersion was not observed. This study identifies seven significant factors associated with railroad crossing crashes through the main and variant models. With regard to explanatory factors on crossing safety, the total traffic volume, daily train volume, presence of commercial area around crossings, distance of train detector from crossings, time duration between the activation of warning signals and gates, crossing types, and speed hump were found to affect the safety of railroad crossings.

• Annals of Rehabilitation Medicine
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• v.42 no.6
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• pp.863-871
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• 2018

Objective To evaluate the association between progression of curvature of scoliosis, and correction for functional component in patients with juvenile idiopathic scoliosis (JIS). Methods We retrospectively reviewed medical data of patients prescribed custom molded foot orthosis (FO) to correct inequality of RCSPA (resting calcaneal stance position angle), and chose 52 patients (26 females, 26 males) with Cobb angle ${\geq}10^{\circ}$ in radiology and uneven pelvic level at iliac crest by different RCSPA (${\geq}3^{\circ}$) as a factor of functional scoliosis. They had different hump angle ${\geq}5^{\circ}$ in forward bending test, for idiopathic scoliosis component. Their mean age and mean period of wearing FO were $79.5{\pm}10.6months$ and $18.6{\pm}0.70months$. Results Cobb angle was reduced from $22.03^{\circ}{\pm}4.39^{\circ}$ initially to $18.86^{\circ}{\pm}7.53^{\circ}$ after wearing FO. Pelvis height difference and RCSPA difference, were reduced from $1.07{\pm}0.25cm$ initially to $0.60{\pm}0.36$, and from $4.25^{\circ}{\pm}0.71^{\circ}$ initially to $1.71^{\circ}{\pm}0.75^{\circ}$ (p<0.01). Cobb angle improved most in 9 months. However, there was no significant improvement for those with more than $25^{\circ}$ of Cobb angle initially. Mean Cobb angle improved in all age groups, but patients less than 6 years had clinically significant improvement of more than $5^{\circ}$. Conclusion JIS can have functional components, which should be identified and managed. Foot orthosis is useful in correcting functional factors, in the case of pelvic inequality caused by different RCSPA, for patients with juvenile idiopathic scoliosis.

• Journal of Korea Water Resources Association
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• v.42 no.12
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• pp.1079-1089
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• 2009

The objective of this study is to develop the accurate, robust and high resolution two-dimensional numerical model that solves the computationally difficult hydraulic problems, including the wave front propagation over dry bed and abrupt change in bathymetry. The developed model in this study solves the conservative form of the two-dimensional shallow water equations using an unsplit finite volume scheme and HLLC approximate Riemann solvers to compute the interface fluxes. Bed-slope term is discretized by the divergence theorem in the framework of FVM for application of unsplit scheme. Accurate and stable SGM, in conjunction with the MUSCL which is second-order-accurate both in space and time, is adopted to balance with fluxes and source terms. The exact C-property is shown to be satisfied for balancing the fluxes and the source terms. Since the spurious oscillations in second-order schemes are inherent, an efficient slope limiting technique is used to supply TVD property. The accuracy, conservation property and application of developed model are verified by comparing numerical solution with analytical solution and experimental data through the simulations of one-dimensional dam break flow without bed slope, steady transcritical flow over a hump and two-dimensional dam break flow with a constriction.

• Korean Journal of Agricultural and Forest Meteorology
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• v.20 no.3
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• pp.233-242
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• 2018

This study explored the richness patterns of vascular plant species and evaluated the effects of the climatic and habitat variables on the observed patterns along elevational gradients on the Mt. Baekhwa, South Korea. Plant data were recorded from 70 plots and a total of 187 plant species with 78 woody and 109 herbaceous species were recorded along two study transects, the Banyasa and Bohyunsa transects, on the Mt. Baekhwa. A total of 154 plant species with 66 woody and 88 herbaceous species and 131 plant species with 58 woody and 73 herbaceous species were recorded along the Banyasa and Bohyunsa transects, respectively. We used simple ordinary least squares regression model, multi-model inference and variation partitioning to analyze the relative contribution of climatic and habitat variables on the elevational richness patterns. Species richness pattern for vascular plants along the Banyasa transect monotonically decreased with elevation, whereas plant species richness showed reversed hump-shaped pattern along the Bohyunsa transect. Although the elevational patterns of species richness for vascular plants were different between the both transects, habitat variables are more important predictors than climatic variables for the elevational patterns of plant species richness along our study transects on the Mt. Baekhwa. These results indicate that elevational diversity patterns of vascular plants may be different even between nearby elevational transects in a mountain ecosystem but the diversity patterns may be controlled by same drivers.