• The Korean Journal of Physiology and Pharmacology
• /
• v.18 no.5
• /
• pp.441-446
• /
• 2014

Ursolic acid (UA), a type of pentacyclic triterpenoid carboxylic acid purified from natural plants, can promote skeletal muscle development. We measured the effect of resistance training (RT) with/without UA on skeletal muscle development and related factors in men. Sixteen healthy male participants (age, $29.37{\pm}5.14$ years; body mass index=$27.13{\pm}2.16kg/m^2$) were randomly assigned to RT (n=7) or RT with UA (RT+UA, n=9) groups. Both groups completed 8 weeks of intervention consisting of 5 sets of 26 exercises, with 10~15 repetitions at 60~80% of 1 repetition maximum and a 60~90-s rest interval between sets, performed 6 times/week. UA or placebo was orally ingested as 1 capsule 3 times/day for 8 weeks. The following factors were measured pre-and post-intervention: body composition, insulin, insulin-like growth factor-1 (IGF-1), irisin, and skeletal muscle strength. Body fat percentage was significantly decreased (p<0.001) in the RT+UA group, despite body weight, body mass index, lean body mass, glucose, and insulin levels remaining unchanged. IGF-1 and irisin were significantly increased compared with baseline levels in the RT+UA group (p<0.05). Maximal right and left extension (p<0.01), right flexion (p<0.05), and left flexion (p<0.001) were significantly increased compared with baseline levels in the RT+UA group. These findings suggest that UA-induced elevation of serum irisin may be useful as an agent for the enhancement of skeletal muscle strength during RT.

• The Korean Society of Law and Medicine
• /
• v.17 no.1
• /
• pp.139-168
• /
• 2016

Two alternative dispute resolutions for medical dispute have been operated under the States of German Medical Associations. The first is the medical mediation committee of North german area, the other is the advisory committee on medical errors in North-Rhine area. The former has focused on the mediation itself, the latter commission has focused on the expert review itself whether the physician has maintained reasonable care in diagnosis and treatment. Even though these organizations have maintained under the medical associations, to maintain the neutrality on legal and medical decision, the North German mediation committee is composed of a lawyer and a medicine doctor respectively and North-Rhine advisory committee has a lawyer chair person and four medicine doctors. The main difference of Korean Medical Dispute Mediation Agency in respect from the german system is that expert review is subordinated to the mediation process. The neutrality of expert review is suspected from the medicine doctors. The neytrality and the efficiency should be improved to treat the medical disputes. To do so, lawyer and medicine doctor work together in mediation process and lawyer should manage the expert review process but not involved. Mediation process and expert review should be checked and balanced, and they could be developed as a separated process itself.

• Journal of Food Hygiene and Safety
• /
• v.29 no.3
• /
• pp.165-169
• /
• 2014

Salmonella spp. and Brucella spp. are associated with considerable diseases of both humans and animals. In addition, these microorganisms cause the economic loss in animal farming and food industry. In this study, the disinfection efficacy of a commercial disinfectant, composed to povidone-iodine was evaluated against S. typhimurium and B. ovis. A bactericidal efficacy test by broth dilution method was used to determine the lowest effective dilution of the disinfectant following exposure to test bacteria for 30 min at $4^{\circ}C$. The disinfectant and test bacteria were diluted with hard water (HW) or organic matter suspension (OM) according to treatment condition. On HW condition, the bactericidal activity of the disinfectant against S. typhimurium and B. ovis was 400 and 150 fold dilutions, respectively. On OM condition, the bactericidal activity of the disinfectant was 5 and 20 fold dilutions against S. typhimurium and B. ovis, respectively. As the disinfectant composed to povidine-iodine possesses bactericidal efficacy against animal pathogenic bacteria such as S. typhimurium and B. ovis, the disinfectant solution can be used to control the spread of bacterial diseases.

• Economic and Environmental Geology
• /
• v.53 no.3
• /
• pp.321-336
• /
• 2020

The Headquarters for Earthquake Research Promotion (HERP) represents the upper-most level of Japan's earthquake disaster prevention governance. Its policy committee establishes the national earthquake investigation research promotion plan. The earthquake investigation committee of HERP collects survey geo-data and evaluates the research results of each earthquake disaster prevention agency. The establishment of an earthquake-related geo-resilience research strategy is both necessary and desirable for Korea. The concept of geo-resilience entails the ability to improve disaster resilience through the application of research results and the convergence of geoscience with science and technology (S&T) including the humanities and social sciences. The achievement of geo-resilience requires a national long-term roadmap and strategy for earthquake prediction research, the development of earthquake disaster prediction and prevention technology, Geo-ICT convergence technology development, implementation of a geocyber physics system (Geo-CPS), the use of geo-mimetics, and geoscientific R&D as it relates to local communities. Through such efforts, the national research institutes of Korea will be able to develop earthquake prediction capacities in relevant fields, reinforce proactive response capabilities, enhance community-level confidence in geodata and its research results, foster next-generation geoscientific manpower, and expand geoscientific infrastructure.

• Ocean and Polar Research
• /
• v.41 no.1
• /
• pp.35-46
• /
• 2019

The purpose of this study is to identify factors influencing fish production of shallow-sea aquaculture in South Korea. This study employed the two-way fixed effect and random effect models based on the panel models and also the difference between GMM and system GMM models based on the dynamic panel models using the amount of fish farming production, the number of stocked fry, the number of cultured fish, the amount of inputted feed, the farming area, the number of workers, and the sales price data from 2010 to 2017. First, the two-way fixed effect model of the panel models was selected by panel characteristics, time characteristics and Hausman tests and also the model was statistically significant. As a result of the two-way fixed effect model, the number of stocked fry, the amount of inputted feed, and the number of workers were identified as factors that increase the fish production of shallow-sea aquaculture. However, the number of cultured fish and the sales price were analyzed as factors that reduce the fish production of shallow-sea aquaculture. Second, the system GMM model of the dynamic panel models was selected by Hansen test and Arellano-Bond test in order to identify whether or not the over-discrimination condition is appropriate. Based on the system GMM model, the number of stocked fry, the amount of inputted feed, the number of workers in this year and 1 year ago, the number of cultured fish 2 years ago, and the sale price 3 years ago were analyzed as factors that increase the fish production of shallow-sea aquaculture. However, the amount of fish farming production 1, 2, 3 years ago, the farming area in this year, and the number of cultured fish in this year and 1 year ago were identified as factors that reduce the fish production of shallow-sea aquaculture. In conclusion, this study suggests that it is desirable to control the amount of stocked fry rather than to expand the farming area for fish farming in shallow-sea aquaculture, so as to keep the sale price at a certain level by maintaining the appropriate amount of fish production.

• Korean Association of Arts Management
• /
• no.58
• /
• pp.49-88
• /
• 2021

Contemporary literary writers engage in multiple jobs and activities in the changing industrial and institutional environments to manage careers and produce literary value. The notion of art entrepreneurship envisages writers as the actors pursuing optimal rewards at both literary and economic levels by applying creative knowledge and skills to the management of career. In contrast, the notion of creative labor argues that writers go through career insecurity as they pursue self-fulfillment through work. This paper critically reviews two notions and suggests the notion of cultural intermediaries to better understand their production of literary value within the variety of relational contexts where they are situated. This paper analyzes the structures and characteristics of a wide range of intermediary practices by literary writers. Based on the analysis, I argue that the autonomy of literary value the writers construct and their status of entrepreneur-labourer are contingent upon the relational contexts within which they practice the intermediary work. I also suggest that literary writers by utilizing a variety of tactics cope with the changes that shape the autonomy of literature and invent new roles and identities as cultural intermediaries. Furthermore, literary writers develop not only self-management skills to adapt to the changing environments but also the collective capacity to cope with the constraints derived from the structural change of literary production and circulation. Finally, I argue that the art management discipline can reflect upon and support the creative endeavors of literary writers by embracing the critical understanding of structural changes suggested by the disciplines of humanities and social sciences.

• Journal of Environmental Health Sciences
• /
• v.42 no.4
• /
• pp.266-273
• /
• 2016

Objectives: This study evaluated the virucidal efficacy against avian influenza virus (AIV) of a disinfectant spray containing 0.25% grapefruit seed extract, 0.2% citric acid, 0.0625% malic acid and 0.0125% benzalkonium chloride. Methods: The disinfectant spray was diluted several times with hard water (HW) and organic matter (OM). Two point five mL of each diluent was added into each test tube, and 2.5 mL of AIV suspension was inserted into each test tube. After 30 minutes of virus-disinfectant contact reaction at $4^{\circ}C$, 2.5 mL of 10% inactivated fetal bovine serum was added into each test tube to neutralize the sanitizer efficacy. The neutralized solutions were serial 10-fold dilutions with phosphate buffer solution, and 0.2 mL of the diluents was injected into the allantoic cavity of five ten-day-old-chickens per dilution time. After incubation of the embryos for five days, the viability of the AIV was examined by hemagglutination titer. The valid dilution of the disinfectant spray was estimated according to the dilution time that the virus titer was inactivated more than $10^4$ 50% egg-infective dose (EID50)/mL compared with pathogen control. Results: In HW and OM conditions, the valid dilutions of the disinfectant spray against AIV were seven- and three-fold dilutions, respectively. The AIV titer of the pathogen control was more than 6.1 log10EID50/mL, and there was no embryonic toxicity. Conclusion: The present study showed that this disinfectant spray has effective virucidal activity against AIV.

• Quality Improvement in Health Care
• /
• v.21 no.2
• /
• pp.58-72
• /
• 2015

Objectives: This study was conducted as descriptive correlation research in order to survey healthcare personnel(HCP)'s awareness of patient safety culture and their recognition of standard precautions, and to examine the correlation between the two factors. Methods: The subjects were 400 HCPs including 80 doctors, 240 nurses, and 80 medical technicians from two general hospitals. The questionnaire used in the survey consisted of 9 questions on general characteristics, 44 on the perception of patient safety culture, and 21 on the recognition of standard precautions. Results: According to the subjects' general characteristics, the score was significantly higher in those aged over 40 than in those aged 30-39. In addition, it was significantly higher in managers than in practitioners, in those with work experience of less than a year than in those with 5-9 years. The score was also significantly higher in those working 8 hours a day than in those working over 10 hour a day. The number of medical accident reports according to the subjects' general characteristics was significantly larger in nurses than in doctors, in managers than in practitioners, and in those with 10 years' or longer experiences than in those with less than a year. In the awareness of standard precautions according to the subjects' general characteristics, the score was significantly higher in female workers than in male workers, and in managers than in practitioners. As a whole, the subjects' awareness of patient safety culture and their recognition of standard precautions showed a significant correlation with each other. Conclusion: From the result of this study, sufficient work force and the promotion of organizational culture for safety is needed in order to guarantee patient safety. Likewise, these results suggest that experience, job skill, and adequate working hours have a positive effect on the awareness of patient safety culture and the recognition of standard precautions.

• Science of Emotion and Sensibility
• /
• v.14 no.2
• /
• pp.245-256
• /
• 2011

This study consists of two sections to figure out the relationship between autistic features and empathizing-systemizing traits. For the first section, the research involved 355 university students to measure their EQ, SQ-R and AQ. As a result, it is found that AQ was negatively correlated to EQ, and D score(relative difference between EQ and SQ-R of the individuals), but it was not significantly related to SQ-R. It means that the subject has high AQ if he has relatively lower EQ than SQ-R. For the second section, the subjects were divided into two groups based on their AQ score; the subjects who had a tendency of autism and the subjects who did not. The test measured how these two groups were different in terms of facial expressions' recognition according to the tendency of autism, facial expression presenting areas(whole face, eyes-alone, mouth-alone) and different types of emotions(basic and complex emotions). As a result, the subjects who had a tendency of autism were lower at judging facial expressions than the subjects who did not. Also, the results showed that the subjects judged better on the condition of basic emotions more than complex emotions, the whole face more than eyes-alone and mouth-alone. Especially, for the eyes-alone condition, the subjects who had a tendency of autism were lower at judging facial expressions than the subjects who did not. This study suggests that empathizing traits and facial expressions' recognition are related to the tendency of autism.

• Journal of Internet Computing and Services
• /
• v.19 no.5
• /
• pp.67-75
• /
• 2018

According to Symantec's Internet Security Threat Report(2018), Internet security threats such as Cryptojackings, Ransomwares, and Mobile malwares are rapidly increasing and diversifying. It means that detection of malwares requires not only the detection accuracy but also versatility. In the past, malware detection technology focused on qualitative performance due to the problems such as encryption and obfuscation. However, nowadays, considering the diversity of malware, versatility is required in detecting various malwares. Additionally the optimization is required in terms of computing power for detecting malware. In this paper, we present Stream Order(SO)-CNN and Incremental Coordinate(IC)-CNN, which are malware detection schemes using CNN(Convolutional Neural Network) that effectively detect intelligent and diversified malwares. The proposed methods visualize each malware binary file onto a fixed sized image. The visualized malware binaries are learned through GoogLeNet to form a deep learning model. Our model detects and classifies malwares. The proposed method reveals better performance than the conventional method.