• 제목/요약/키워드: Human-Body Effect

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LVDC 배전계통의 접지방식에 따른 인체안전 및 계통영향 분석 (Analysis of Human Safety and System Effect according to Grounding Scheme in LVDC Distribution System)

  • 오윤식;한준;권기현;김두웅;노철호;정택현;김철환
    • 전기학회논문지
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    • 제63권5호
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    • pp.608-614
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    • 2014
  • Recent developments and trends in the electric power consumption clearly indicate an increasing use of DC in end-user equipment. According to the trends, new DC power distribution systems have been researched and developed although we presently enjoy a predominantly AC power distribution system. We can use various grounding schemes in DC distribution system as well as in AC distribution system to protect human body and equipments. However, we need to evaluate carefully which grounding scheme is appropriate for a specific system before applying those schemes. In this paper, we analyze the human safety and system effect according to various grounding schemes in Low Voltage DC (LVDC) distribution system. Some components in LVDC distribution system are modeled and computer simulations are conducted by using ElectroMagnetic Transient Program (EMTP).

Effect of Methyl Gallate on 1-Nitropyrene-Induced Keratinocyte Toxicity in a Human and Canine Skin Model

  • Lee, Woo Jin;Kim, Min Jeong;Choi, Hyun-Wook;Lee, Jeong Jae;Jung, Sung Keun
    • Journal of Microbiology and Biotechnology
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    • 제32권7호
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    • pp.869-876
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    • 2022
  • The skin, which is the largest organ of the human body, is in direct contact with pollutants in the surrounding atmosphere. Meanwhile, 1-nitropyrene (1-NP), the most abundant nitro-polycyclic aromatic hydrocarbon found in particulate matter, is known to have carcinogenic effects; however, studies on its toxicity in human and canine skin are still needed. In this study, we investigated 1-NP-induced apoptosis and inflammatory pathways in HaCaT cells. In addition, we also measured the cytoprotective effect of methyl gallate (MG), which is widely distributed in medicinal and edible plants and is well known for its anti-inflammatory and antioxidant properties. MG inhibited 1-NP-induced cell death and apoptosis pathways, including the cleavage of PARP and activation of caspase-3, -7, and -9. MG also suppressed 1-NP-induced COX-2 expression and phosphorylation of mitogen-activated protein kinases (MAPKs) and MAPK kinases (MAPKKs). Our findings suggest that 1-NP induces skin toxicity in human and canine through apoptosis and inflammatory responses, and moreover, that this can be prevented by treatment with MG.

체질푸드가 간호사의 스트레스 감소와 NK세포 활성도에 미치는 영향 (Effects of Constitutional Food on Nurse's NK Cell Activity and Stress Reduction)

  • 박선미
    • 한국콘텐츠학회논문지
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    • 제19권3호
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    • pp.500-509
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    • 2019
  • 본 연구는 체질푸드가 간호사의 자연치유력증진에 있어서 스트레스 감소와 NK세포 활성도에 미치는 영향에 대해 밝히고자 하였으며, 이를 통해 체질푸드가 인간의 건강 예방과 치유에 효과적인지를 고찰하였다. 연구는 경기도 한 종합병원에서 현재 1년 이상 근무 경력이 있는 간호사 22명을 대상으로 30일 동안 진행되었다. 본 연구에서는 스트레스 측정을 위해 유비오맥파측정기(uBioClip v70)를 사용하였고 NK세포 활성도에 대해서는 혈액검사를 통해 진행하였다. 수집된 자료처리는 통계분석 프로그램인 SPSS 21을 통해 대응표본 t검증으로 진행하였으며, 황제내경과 장상학에 근거한 체질분류 후 참여자의 체질에 알맞은 체질 푸드를 제공하여 실시하였다. 연구 결과, 체질푸드의 스트레스 감소에 미치는 영향은 유의한 정(+)의 효과를 나타내었고, NK세포 활성도에 대해서 체질푸드가 효과적인 것으로 나타났다. 본 연구는 의의는 다음과 같다. 첫째, 현대인의 건강을 위협하는 주 요소인 스트레스에 대해 체질푸드를 통한 자연치유력 강화가 스트레스에 대한 저항력을 높여줌으로써 질병에 대한 예방 효과가 있다는 점이다. 둘째, 질병의 예방과 치료에 있어서 면역세포 활성도는 매우 중요한데, 체질푸드를 통한 NK세포 활성도를 높여줌으로써 인체의 자연치유력을 증대시킬 수 있다는 점이다.

호르몬수면상실이 에너지와 대사에 미치는 영향 (The Effect of Sleep Loss on Energy and Metabolism)

  • 강승걸
    • 수면정신생리
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    • 제19권1호
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    • pp.5-10
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    • 2012
  • The release of hormones and the metabolism of human body are controlled by the circadian rhythm related to sleep-wake cycle. Growth hormone, prolactin, thyroid stimulating hormone, cortisol, glucose, and insulin-secretion rates fluctuate according to the sleep-wake cycle. In addition, sleep is related to the appetite regulation and carbohydrate and other energy metabolism. Hypocretin (orexin), an excitatory neuropeptide, regulates waking and diet intake, and the poor sleep increases diet intake. The short sleep duration increases one's body mass index and impairs the function of the endocrine and metabolism, causing increases in the risk of glucose intolerance and diabetes. The poor sleep quality and sleep disorders have similar impact on the metabolic function. In short, the sleep loss and the poor quality of sleep have a detrimental effect on the endocrine and energy metabolism. The improvement of sleep quality by the future research and appropriate clinical treatment would contribute to the decrease of the metabolic diseases such as diabetes.

마우스에서 Interleukin-2가 RD-995 종양세포에 미치는 항암효과 (Effect of interleukin-2 on antitumor response against intraperitoneal RD-995 tumor in mice)

  • 권오덕
    • 한국동물위생학회지
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    • 제25권3호
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    • pp.309-314
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    • 2002
  • Recombinant interleukin-2(IL-2) has demonstrated as an antineoplastic agent in mice and human, but the relatively low response rates observed in clinical trials. Therefore, the present study was undertaken in order to evaluate therapeutic activities of IL-2 for the establishment of therapeutic applications. At the onset of the experiment, normal C3H/HeN mice were injected with 5$\times$10$\^$6/ RD-995 tumor cells, murine ultraviolet radiation-induced fibrosarcoma, intraperitoneally. Beginning on day 6, experimental groups were treated with a 5-day course of IL-2(subcutaneous injection of 30,000 IU every 12 hours for 5 days). The result of this experiment revealed that body weight gradually decreased from 20th day in control mice. Subcutaneous IL-2 therapy prevented partially decrease body weight, and prolonged survival of mice compared with control group.

서열환경하에서 체지방률에 따른 오전과 오후의 체온조절반응 (Thermoregulatory Responses of AM & PM with Body Fat Rate at a Hot Environment)

  • 김성숙;이정숙;김희은
    • 한국의류산업학회지
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    • 제7권3호
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    • pp.315-320
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    • 2005
  • With regard to the fact that temperature of human body remains almost constant at $37^{\circ}C$, changes by circadian variation, this study intended to investigate the effect of circadian rhythm on physiological responses of human body according to body fat rate. Fifteen healthy adult women were recruited for this study and were measured body fat as a method of bio impedance. We organized subjects into three groups ; low body fat group(group L-less than 20% of body fat), medium body fat group(group M-20%~30% of body fat) and high body fat group(group H-more than 30% of body fat). The experiment was carried out in a climate chamber of $32^{\circ}C$, 60% RH with the repeat of 'Exercise' and 'Rest' period. Subjects participated in two experiments, one is morning experiment(called 'AM'), the other is afternoon experiment (called 'PM'). The results of this study are as follows ; As to the variation of rectal temperature, group L and M had a significant difference in the time of the day between AM and PM, but group H had almost the same rectal temperature in the two kinds of experimental time. The reason why group H had a smaller difference in the circadian rhythm of rectal temperature in this study is estimated at the Budd et al.(1991)'s results that body fat had effects on reduction in thermogenesis, radiation, mean skin temperature, and increase in insulation of the tissues. Group M had the highest mean skin temperature in the 'PM'. All the 3 groups didn't have stable values in 'AM'. But it showed more stable in 'PM' than 'AM'. Sweat rate was the highest in group H in both 'AM' and 'PM'. Group M had larger sweat rate in 'PM' than 'AM'. but in group L and H, sweat rate was almost the same in two kinds of time of the day. This result suggests that who have more or less body fat have larger difference in sweat rate between morning and afternoon than who have normal body fat.

발목에 적용한 무게 부하가 뇌졸중 환자의 보행요소에 미치는 영향 (Effect of Weight Loads Applied to the Ankle on Walking Factors of a Stroke Patient)

  • 이수경
    • PNF and Movement
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    • 제16권2호
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    • pp.179-185
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    • 2018
  • Purpose: This study aimed to analyze the visual and spatial elements of the gait of a stroke patient who had diverse ankle weight loads applied, according to weight changes. Methods: The subject was a 57-year-old stroke patient diagnosed and hospitalized with a left intracerebral hemorrhage. A weight equivalent to 0%, 1%, and 2% of his body weight was applied to the area 5cm upward from the ankle using a Velcro strap. He was then trained on a treadmill, receiving a six-minute walk test to evaluate his gait ability. A gait analyzer was used to collect visual and spatial elements, such as gait distance, gait velocity, cadence, step length, stride length, and swing phase, according to a weight load equivalent to 0%, 1%, and 2% of his body weight. Results: According to the results of applying 0%, 1%, and 2% of his body weight on the ankle, except for gait velocity, his gait distance, cadence, step length, stride length, and swing phase were higher when 1% of his body weight was applied compared to 0% or 2% of his body weight. Conclusion: Applying a weight equivalent to 1% of the body weight to the ankle positively affected the visual and spatial element of the gait and heightened the efficiency of exercise during treadmill training, a gait-training tool generally used for stroke patients. However, the result is difficult to generalize because the number of subjects was small with only one subject.

수중에서의 인체에 가해지는 전기적 현상에 관한 연구 (A Study on the Human body Model shocked Electric installation in Underwater)

  • 우정현;박하용;송우창;김남석
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2008년도 제39회 하계학술대회
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    • pp.1338-1339
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    • 2008
  • In this paper, charging part by basic from Andrew's body model research to second a danger have affect on remaining and rehabilitation humans in space under water. The construction of a circuit make to Andrew's body model. It compare that voltages measure a hand, a breast, a groin and electric currents measure an arm, a breast, a leg with safety a limit of body through an electric current. Out of result, it research that magnitude and wave of body passing an electric current give the effect to the heart control a signal and it have affect on direct the ventricle of the heart in detail motion. A thing of this sort get through to the simulation by the ATP-Draw program. The results from above, it is publish one's research work with safety a limit electric angle take measurement of resistance a body in under water and to the voltage and electric current passing each parts.

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The effect of early arm exercise on drainage volume after total mastectomy and tissue expander insertion in breast cancer patients: a prospective study

  • Joo, Oh Young;Moon, Seung Jin;Lee, Dong Won;Lew, Dae Hyun;Lee, Won Jai;Song, Seung Yong
    • Archives of Plastic Surgery
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    • 제48권6호
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    • pp.583-589
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    • 2021
  • Background In prosthesis-based breast reconstruction patients, the drain tends to be kept in place longer than in patients who undergo only mastectomy. Postoperative arm exercise also increases the drainage volume. However, to preserve shoulder function, early exercise is recommended. In this study, we investigated the effect of early exercise on the total drainage volume and drain duration in these patients. Methods We designed a prospective randomized trial involving 56 patients who underwent immediate breast reconstruction following mastectomy using tissue expanders. In each group, the patients were randomized either to perform early arm exercises using specific shoulder movement guidelines 2 days after surgery or to restrict arm movement above the shoulder height until drain removal. The drain duration and the total amount of drainage were the primary endpoints. Results There were no significant differences in age, height, weight, body mass index, or mastectomy specimen weight between the two groups. The total amount of drainage was 1,497 mL in the early exercise group and 1,336 mL in the exercise restriction group. The duration until complete removal of the drains was 19.71 days in the early exercise group and 17.11 days in the exercise restriction group. Conclusions Exercise restriction after breast reconstruction did not lead to a significant difference in the drainage volume or the average time until drain removal. Thus, early exercise is recommended for improved shoulder mobility postoperatively. More long-term studies are needed to determine the effect of early exercise on shoulder mobility in prosthesis-based breast reconstruction patients.

직물 센서의 모양과 부착 위치가 사지 동작 센싱 의류의 센싱 성능에 미치는 영향 (Effect of the Shape and Attached Position of Fabric Sensors on the Sensing Performance of Limb-motion Sensing Clothes)

  • 조현승;양진희;전동진;이주현
    • 감성과학
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    • 제20권3호
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    • pp.141-150
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    • 2017
  • 본 연구에서는 E-textile 기반 신축성 센서의 모양과 부착 위치가 동작 센싱 성능에 미치는 영향을 분석하고, 이를 통해 인체 동작 센싱에 가장 적합한 의복 구조 요건을 규명하고자 하였다. 실험 대상 아동에게 센서의 모양과 부착 위치에 따라 조작된 실험복을 착의시킨 후 60 deg/sec의 속도로, $60^{\circ}$, $90^{\circ}$, $120^{\circ}$의 동작 각도별로 팔과 다리의 굽힘, 폄 동작 의한 직물 센서의 신장과 수축에 따른 전압의 변화량을 측정하였으며, 가속도 센서를 함께 부착하여 동작의 일치도를 검증하였다. 또한 아동의 모형 팔과 다리를 제작하여 이를 대상으로 동일한 실험을 수행함으로써 인체의 팔, 다리의 동작 실험 결과와 비교하였다. 분석 결과 센서의 모양에서는 모형 대상 실험과 아동 대상 실험 모두에서 보트형의 센서 보다 장방형의 센서가 더 균일하고 안정적인 경향을 보여 재현성과 신뢰성이 높은 것으로 나타났다. 센서의 부착 위치는 모형 대상 실험에서는 팔꿈치와 무릎의 관절부로부터 4 cm 아래 지점에 부착된 경우, 아동 대상 실험에서는 팔꿈치와 무릎의 관절부에 위치했을 때 재현성과 신뢰성이 더 높았다. 본 연구에서는 아동의 사지 동작 측정에 적합한 센서를 개발하고 동작 센싱에 적합한 센서의 모양과 부착 위치의 조건을 분석하였으며, 의복에 통합된 유연한 직물 센서를 활용하여 인체 부위별 동작 센싱이 가능하다는 것을 규명하였다.