• 디지털융복합연구
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• 제19권8호
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• pp.173-184
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• 2021

현대 조직에서 고위급 임원들의 이직이 점차 증가하고 있음에도, 대부분의 기존 연구들에서는 임원들의 비자발적 이직/퇴직의 함의에 대한 연구에 치중해있는 실정이다. 본 연구에서는 기존 연구의 한계를 탈피하기 위해, 조직원 이동과 창업자 연구에 기반하여 임원들의 자발적 이직에 관한 이론적 모형을 제언한다. 첫째, 최고경영자로 창업자가 된 경우 기존 기업에 부정적 영향을 줄 것이나, 두 기업이 협력적 관계가 형성될수록 부정적 관계는 줄어들 것이다. 둘째, 스핀오프의 경우 기존 기업에 긍정적 영향을 줄 것이나, 스핀오프 기업의 성과가 저조할수록 긍정적 관계는 약화될 것이다. 마지막으로, 경쟁사로 이직하는 경우에는 부정적, 협력사로 이직하는 경우에는 긍정적 영향을 기존 기업의 성과에 줄 것이다. 본 연구에서는 임원들의 자발적 이직이 기존 기업의 성과에 미치는 영향력이 임원들의 향후 활동 양태에 따라 달라질 것이라 주장한다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 제36회 하계학술대회 논문집 D
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• pp.2771-2773
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• 2005

In network human-robot interaction, human can access services of a robot system through the network The communication is done by interacting with the distributed sensors via voice, gestures or by using user network access device such as computer, PDA. The service organization and exploration is very important for this distributed system. In this paper we propose a new agent-based framework to integrate partners of this distributed system together and help users to explore the service effectively without complicated configuration. Our system consists of several robots. users and distributed sensors. These partners are connected in a decentralized but centralized control system using agent-based technology. Several experiments are conducted successfully using our framework The experiments show that this framework is good in term of increasing the availability of the system, reducing the time users and robots needs to connect to the network at the same time. The framework also provides some coordination methods for the human robot interaction system.

• 대한의생명과학회지
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• 제12권4호
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• pp.405-411
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• 2006

Heterotrimeric GTP binding proteins (G proteins) mediate signal transduction generated by neurotransmitter and hormones. Among G-proteins, Go is classified as a member of the Go/Gi family and the most abundant heterotrimeric G protein in brain. Most of the mechanistic analyses on the activation of Go indicated its action to be mediated by the $G{\beta}{\gamma}$ dimer because downstream effectors for its ${\alpha}$ subunit have not been clearly defined. To determine the downstream effectors of alpha subunits of Go ($Go{\alpha}$), we used yeast two-hybrid system to screen $Go{\alpha}$ interacting partners in cDNA library from the human brain. A brain specific high mobility group box containing protein (BHX), A possible transcription factor, was identified as a $Go{\alpha}$ interacting protein. We confirmed interaction between $Go{\alpha}$ and BHX employing in vitro affinity binding assay. Moreover, active form of $Go{\alpha}$ preferentially interacts with BHX than inactive farm. Our findings indicate that $Go{\alpha}$ could modulate gene expression via interaction with BHX during neuronal or brain development.

• 대한가정학회지
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• 제30권4호
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• pp.153-165
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• 1992

The objectives of this study were to develop a probabilistic model for both hypotheses testing and mobility prediction. Methodologies being used for the analysis include multivariated analysis for descriptive statistics and logit model for hypotheses testing and prediction. The study used questionaire survey data conducted by Korean Research Institute for Human Settlements (KRIHS) in 1988. There were a total of 1,620 Samples, and both SPSS and Limdep software packages were used for statistical analysis and model testing. The major findings were highlighted as follows; The residential mobility over family life span by the social class were developed with the use of the probability model. Most of households in low class moved downwardly. They had lived the small-owned single detached house in first family life span and moved into the small-rented single detached house in next family life span. Most of households in middle class moved upwardly. They had lived the small-owned apartment in first family life span and moved into the large-owned single detached house in last family life span. Most of households in high class horizontally. They had lived the large-owned single detached house in first family life span and moved into the same one except in last family life span.

• 한국의류학회지
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• 제40권5호
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• pp.921-935
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• 2016

This research analyzed the manual performance of firefighting protective gloves on global markets in order to suggest an evaluation method for firefighting protective gloves wearing comfort. We collected 13 types of firefighting gloves from domestic and international markets (7 types from Korea, 3 types form Europe, 2 types from the U.S and 1 type from Japan). We set the Don-Doff test as a basal requirement for moving toward to further manual performance tests that consist of: ASTM dexterity test, Minnesota dexterity test, Bennett hand tool test and ASTM torque test. All gloves were evaluated in dry and wet conditions, we included eight current male firefighters ($43.4{\pm}7.0yr$ in age, $173.1{\pm}4.4cm$ in height, $79.9{\pm}9.2kg$ in body mass) for the tests. Four gloves (1 Korea, 1 U.S, 1 Germany, and 1 Japan) out of thirteen firefighting gloves passed the Don-Doff test and had great subject preferences. There was no significant difference between dry and wet conditions on the ASTM dexterity test, Minnesota dexterity test, Bennett hand tool test and ASTM torque test. However, Japanese gloves had the greatest score and showed 3-4 times faster completion time on the ASTM dexterity test (p<.05), 1.2-1.5 times faster on the Minnesota dexterity test (p<.05), as fast as the bare hand on Bennett hand tool test (p<.05), and greater performance on the ASTM torque test compared to bare hand. In conclusion, Don-Doff test in wet conditions should be the first step for a mobility evaluation of domestic firefighting protective gloves; subsequently, a comprehensive test assorting ASTM, Minnesota, and Bennett test should be developed as a second step. The current ASTM torque test can be adopted as a third step. This three-step-method for evaluating firefighting protective glove mobility can be expected to expand into surveys of other safety gloves in Korea.

• 한국ITS학회 논문지
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• 제22권1호
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• pp.311-326
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• 2023

본 연구는 자율주행차량과 일반차량의 인지 방식과 범위의 차이를 비교하고 미시적 교통시뮬레이션을 활용한 교통안전시설의 설치 및 운영 개선방안을 제안하는 것을 목적으로 하였다. 연구에서는 기존 교통안전표지 설치·관리 업무편람을 검토하고 교통안전시설 중 안전표지를 차량의 행동 변화에 따라 분류하였다. 이후, 분류된 시설에 대해 가상환경에서 시뮬레이션 실험을 통해 안전표지의 설치 위치를 변경해가며 최적 설치지점을 추론하여 개선방안을 제시하였다. 본 연구는 일반 운전자의 시인성을 기준으로 설치된 교통안전시설이 자율주행차량과 일반차량이 혼재된 상황에서 도로 효율성과 안전성에 어떠한 영향을 주는지 확인하였다. 본 연구를 통해 도출한 교통안전시설의 인지에 대한 임곗값은 교통안전시설의 설치·관리에 관한 규칙의 개정 근거로 활용될 수 있다는 데 의의가 있다.

• Animal cells and systems
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• 제7권1호
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• pp.63-68
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• 2003

Until recently, interest in human complement receptor type I (CR1) has focused on immune complex processing, which contributed to our understanding of regulatory mechanism of complement activation. However, the promoter structure and transcriptional regulation of human CR1 gene has not been clear. To study the unique regulation of human CR1 gene expression, we assessed promoter activity of the $5^1$-flanking region of human CR1 gene using transient transfection and gel mobility shift assays. In this study we demonstrated that NF-Y binds to the inverted CCAAT element and that the functional interaction with protein(s) which bind to the GC-rich motif may be necessary for optimal transcription of human CR1 gene. We also show that sequence elements which located at-95/58 and +45/+50 are important for optimal transcription of CR1 gene.

• 약학회지
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• 제22권4호
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• pp.233-237
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• 1978

We studied on the separation of $\alpha$- and $\beta$-chain globins, the conditions of paper electrophoresis and mobility of globins in paper electrophoresis to determine their chain anomaly. Acidic-acetone mothod of Wilson and Smith was found to be more effecient for separating $\alpha$- and $\beta$chain globions than trichloroacetic acid method of Hayashi. The conditions of paper electrophoresis were current of 20v/cm and 0.6mA/cm for three hours at room temperature. In paper electroporesis, the mobility of $\alpha$- -chain globin towards the cathode was greater than that of $\beta$-chain globin. The results showed tha tchain anomaly of $\alpha$- and $\beta$-chain globins can be determined by the method of paper electrophoresis.

• 대한치과교정학회지
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• 제40권1호
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• pp.34-39
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• 2010

본 연구는 교정치료 종료 후 치아동요도의 종단적 계측을 통해 치아 주위조직의 안정화가 언제 나타나는지 살펴봄으로써 교정치료 후 유지장치 장착기간 설정에 도움이 되고자 시행되었다. 고정식 교정장치로 치료가 종료된 20명의 환자를 대상으로 교정장치 제거 직후 그리고 2년까지 3개월 간격으로 Periotest를 이용하여 상악 양측 중절치부터 제1대구치까지 치아동요도를 계측하고 교정치료 후 시간 경과에 따른 동요도 감소 양상을 비교 분석한 결과, 처음 6개월은 급한 양상으로, 다음 6개월은 보다 완만한 양상으로 감소하였고, 이후는 계속 감소하는 양상을 보였으나 통계적으로 유의한 차이를 보이지 않았다. 이상의 결과는 교정치료 후 치아 주위조직의 안정화는 1년이 지나서야 어느 정도 이루어짐을 그리고 처음 6개월은 매우 불안정함을 나타내는 것으로, 교정장치 제거 후 유지장치가 치료 후 1년간은 필요함을, 특히 처음 6개월 동안은 매우 중요함을 시사하였다.

• BMB Reports
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• 제31권6호
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• pp.565-571
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• 1998

The expression of the endogenous human apolipoprotein(apo)E gene was significantly induced when HepG2 cells were treated with exogenous 25-hydroxy-cholesterol. This sterol-mediated apoE gene upregulation appears to require the participation of a positive element for the apoE gene transcription (PET) ( -169/ -140), a core sequence of upstream regulatory element (URE)1 enhancer of the human apoE gene. This PET was renamed as sterol regulatory element (SRE)4 based on its new role as a sensor for the level of intracellular sterol. Furthermore, a gel mobility shift analysis showed that binding activity of the SRE4 binding protein (BP) obtained from HepG2 cells was induced by sterol treatment, while that from either MCF7 or BT20 cells remained unchanged. Binding activity of SRE4BP was also induced in mouse macrophage cells, J774A.1, by sterol treatment, but it was drastically reduced when cells were subjected to treatment of AY-9944, a potent inhibitor for sterol synthesis. However, binding activity of Spl, which is a co-binding protein to the SRE4 region, remained the same in either condition, suggesting that SRE4BP (formally known as PETBP) may be mainly responsible for the sterol-mediated regulation of the apoE gene expression. Deletion analysis of the core binding site of SRE4BP by gel mobility shift assays showed that the minimal sequence of the SRE4BP binding appears to reside between -157 and -140, confirming the identity of SRE4 with the previously determined core sequence of URE1.