• Title/Summary/Keyword: Human evolution

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Economic Production of $\gamma$-Interferon from Recombinant Human Cells in Serum Free Medium by a Moving Aeration Membrane Bioreactor (교반형 막 반응기를 이용한 재조합 인간 세포의 무혈청 배지에 의한 $\gamma$-Interferon의 생산)

  • Park, Young-Shik;Kim, Hyun-Kyu;Lim, Seo-Kyu;Park, Kyung-You;Lee, Hyeon-Yong
    • Microbiology and Biotechnology Letters
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    • v.22 no.4
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    • pp.389-394
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    • 1994
  • 8 X 10$^{6}$(viable cells/ml) of maximum cell density and 9000(IU/ml) of $\gamma$-IFN production were obtained at 55(ml/hr) of a perfusion rate by cultivating HSF cells using a moving membrane aeration bioreactor. This system proves to be an efficient culture process by maintaning 90% of viable cells during the whole cultivation periods. The metabolic molar quotient of glucose to lactate was 0.81 for overall ranges of glucose consumed while the evolution of ammonia was not linearly related to the consumption of glutamine. Low molar conversion ratio was observed in low consumptions of glutamine and high molar conversion ratio in high comsumptions. It also shows that the glutamolysis plays important role in the steady state conditions by evolving larger quantities of ammonia than lactate. At the above of 50 rpm, which is the optimum agitation speed for this bioreactor, the cell growth was severely affected while the IFN production was less decrea- sed, maintaing 1.5 X 10$^{-3}$(IU/cell/day) specific IFN production rate. The cumulatvie $\gamma$-IFN production was 7.2 X 10$^{8}$(IU) for 70 days of the cultivation, which yields 1 X 10$^{7}$ (IU/day) of IFN production rate. Therefore, a commercial production of $\gamma$-IFN by this culture process can be achievable by maintaining the above IFN productivity in a scaled-up culture system.

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The Emergence of Lifestyles in On-line Game World : Understanding Self and Others, Aesthetics of Diversity (게임 세계에서 만드는 삶의 방식과 현실 인간의 persona : 같음과 다름의 배움, 차이의 미학)

  • Whang, Sang-Min;Doh, Young-Yim
    • 한국HCI학회:학술대회논문집
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    • 2008.02b
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    • pp.492-500
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    • 2008
  • This research was conducted in an attempt to understand human lifestyles in on-line game world. Q methodology was used to investigate players in Mabinogi, which is an on-line game(MMORPG). Based on 82 behavior statements, 6 types of on-line game lifestyle were found : Self -Enhancer, Self -Expressionist, Relation-Oriented, Isolation -Antisocial, Social Contributor, and Self-Interest. The behavior patterns of the 6 types were then compared to identify similarities and differences amongst them in psychological meanings and values in the on-line game life. The results showed that the lifestyles in on-line game world encompass both the reflection of the lifestyles in the real world and also the creation of new life patterns that players desire. The process of developing lifestyles in the online game world illustrates the emergence and evolution of human life on new social environment which is established by digital technology. On-line game world can be defined as new life space in which people is able to create new identity and new culture.

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Automatic Selection of Visual Information using Intelligent Content-Based Retrieva (지능형 내용기반검색을 이용한 시각정보 자동추출)

  • 송점동
    • The Journal of Information Technology
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    • v.4 no.2
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    • pp.69-81
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    • 2001
  • In this paper, we examine work in the evolution of content-based retrieval systems that rely on an intelligent infrastructure. Here, we refer to intelligence as the capabilities of the systems to build and maintain situational or world models, utilize dynamic knowledge representations, exploit context and overage advanced reasoning and learning capabilities. We argue that these elements are essential to producing effective systems for retrieving visual information at semantic levels matching those of human perception and cognition. In this paper, we review relevant research on the understanding of human intelligence and construction of intelligent systems in the fields of cognitive psychology, artificial intelligence, semiotics. We also discuss how some of the principal ideas from these fields lead to new opportunities and capabilities for content-based retrieval systems. Finally, we discribe some of our efforts in these directions. In particular, we present MediaNet, a multimedia knowledge presentation framework that facilitate and enable intelligent content-based retrieval.

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Research on the Analog Emotional Communication Appeared in Digital Media Design (디지털미디어를 기반으로 하는 디자인에서의 아날로그감성 커뮤니케이션)

  • Son, Hyun-Ji
    • The Journal of the Korea Contents Association
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    • v.10 no.11
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    • pp.146-153
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    • 2010
  • With the advent of new media richness of technology in the digital age has transformed our lives. The development of technology, the more our lives more convenient, new, future-oriented, while expectations for the digital age, people are longing for warm, human sensibility became. Of modernism and post-modernism appeared to reflect the proliferation of digital media in culture, wandering through the complex has been diversifying. In the digital age stabilizing psychological or mental needs of people who want to begin to emerge as the disfunctional aspects of the digital age has been suggested for the problem. To respond to human emotion on the emotional reaction of users to consider the analog emotional design began to emerge. The analog to digital media to express emotions practical approach to the problem should be attempted. Analog in a digital environment, emotional nature of the digital technology and communication, and symbolic and emotional aspects of people as announced to blend the new extension, change, and an analog emotional design for the evolution and development of new possibilities to investigate the castle.

The Role of Decision-Makers' Platform for Securing Water by Moving Forward to Global Challenges (범지구적 물 문제 해결을 위한 정책입안자 네트워크의 역할)

  • Park, Ji-Seon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2011.05a
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    • pp.21-21
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    • 2011
  • Many Asian countries are suffered from various problems on water, which include the need for increased access to improves water supplies and sanitation through investments in infrastructure and capacity building, the balances water management system between development and ecosystem, and the need to reduce the human populations'vulnerability to water-related disasters, in particular, from climate variability and evolution. Decison makers are the most influential people in policy making and solving global water problems is central issue in eradicating poverty and achieving sustainable development (MDG). They across the world form an integral part of the architecture of national or regional governance. Their role covers a range of decision-making processes including passing legislation, scrutinizing government policy, and representing citizen through the election. We must ensure that these quiet but important issues get the political space, financial priority and public attention they deserve. Regional bodies such as the EU have also enacted legislation which introduces rules on water quality and other enforceable mattera across state boundaries. With this growing body of laws and policies on water issues, the role of decision makers is growing. Recognizing this role, decison makers' platform is essential to provide an opportunity to discuss crucial water issues in each country or region and for the purpose "2010 Parliaments for Water in Asia" has planned and organized to investigate our common issues and goals. During the meeting, we have an opportunity to observe water policy of Bangladesh, Bhutan, China, Mongolia, New Zealand and the Philippines and share the views on what needs to be done to move forward by decision makers for the future of water. In conclusion, the process of developing the decision makers' platform in each region would be ultimately essential point to increase the awareness of the developed and developing countries' roles, knowledge to clarify roles and responsibilities of each stake holders and finally be a major actor for resolving not only water challenges also issues of human settlements.

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Formative characteristics of 3D printing fashion from the perspective of mechanic aesthetic (기계 미학적 관점에서 살펴본 3D Printing 패션의 조형적 특성)

  • Kim, Young-Sam;Lee, Jin-Ah;Kim, Jang-Hyeon;Jun, Yuh-Sun
    • The Research Journal of the Costume Culture
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    • v.23 no.2
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    • pp.294-309
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    • 2015
  • This study aims to clarify the aesthetic values between emotion of human and expression of technology in contemporary fashion as it analyzes formative characteristics of related cases in fashion based on principles of 3D Printing technology and the viewpoint of mechanic aesthetics. The conclusions of this study are as follows. First, 3D Printing fashion is not only expressed diverse variations by its principles of formative methods, materials and properties, but also changes of silhouette by applying system of designers. Second, general characteristics of 3D Printing fashion is represented by various applications in SLS system, and it can be specifically explained application to a portion of clothing, decorative roles of clothing, complicated pattern making through crossing fabrics using 3D scanner and displaying a certain object changing fashion styles, and so forth. Third, the formative characteristics of 3D Printing fashion from the perspective of mechanic aesthetics is as follows. It can be analyzed as the integration of metaphysical values through compared symbolization of natural feature and technical evolution, partial dynamics and interactive velocity-based, formative combinations for abstract expression using architectural components, cosmos images and substantialized structures through images of organic space interacted human shapes. As the mention above, 3D Printing technology can creative a diverse area of fashion, and express images of new technological fashion through various works with continuous development of techniques.

A Synchronized Job Assignment Model for Manual Assembly Lines Using Multi-Objective Simulation Integrated Hybrid Genetic Algorithm (MO-SHGA) (다목적 시뮬레이션 통합 하이브리드 유전자 알고리즘을 사용한 수동 조립라인의 동기 작업 모델)

  • Imran, Muhammad;Kang, Changwook
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.4
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    • pp.211-220
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    • 2017
  • The application of the theoretical model to real assembly lines has been one of the biggest challenges for researchers and industrial engineers. There should be some realistic approach to achieve the conflicting objectives on real systems. Therefore, in this paper, a model is developed to synchronize a real system (A discrete event simulation model) with a theoretical model (An optimization model). This synchronization will enable the realistic optimization of systems. A job assignment model of the assembly line is formulated for the evaluation of proposed realistic optimization to achieve multiple conflicting objectives. The objectives, fluctuation in cycle time, throughput, labor cost, energy cost, teamwork and deviation in the skill level of operators have been modeled mathematically. To solve the formulated mathematical model, a multi-objective simulation integrated hybrid genetic algorithm (MO-SHGA) is proposed. In MO-SHGA each individual in each population acts as an input scenario of simulation. Also, it is very difficult to assign weights to the objective function in the traditional multi-objective GA because of pareto fronts. Therefore, we have proposed a probabilistic based linearization and multi-objective to single objective conversion method at population evolution phase. The performance of MO-SHGA is evaluated with the standard multi-objective genetic algorithm (MO-GA) with both deterministic and stochastic data settings. A case study of the goalkeeping gloves assembly line is also presented as a numerical example which is solved using MO-SHGA and MO-GA. The proposed research is useful for the development of synchronized human based assembly lines for real time monitoring, optimization, and control.

A Study on Demanders' Consciousness by Master Room Planning Types in Apartment House (공동주택에서 마스터룸(Master room) 평면 유형별 수요자 의식 조사 연구)

  • Cho, Sung-Woo;Lee, Su-Yong;Moon, Cul-Seong;Oh, Se-Gyu
    • Journal of the Korean housing association
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    • v.19 no.6
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    • pp.9-20
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    • 2008
  • The residential environment is a place which reflects the gradual evolution of human consciousness because it is a cultural space the term, 'houses' is not relevant in this context as it literally means 'contains'. The long history of human living habits cannot be 'contained' within a space, but can be 'expressed' by a space and by the way the space is used. Furthermore, due to the way it is typically constructed, the basic characteristics of the house usually cannot be rapidly changed to accommodate new habits. However, recent changes that have taken place to the characteristics of the traditional master room suggest that traditional societal values associated with patriarchy have diminished. The current trend where priority is given to children's education also affects such a change. Existing researches related to the master room is confined to the behavioral use of the space and the composition of the physical space, while research on the master room its plane type has not been carried out. Therefore, in this study, apartment model houses are selected, and are classified according to the types of master room. An analysis is then carried out of the master room based on the occupants' requirements in terms of consciousness. Any planning modifications where required are then suggested. This research comprises the followings stages. First, an examination is carried out of existing research on the master room in order to understand its background and spatial components. A definitiones of related terms is also provided. Second, an analysis is carried out of the model houses exhibited at Suwan District, examining the typical standard that has been selected for the master room. Third, an analysis is conducted of the topics and questions to be selected for a questionnaire. Fourth, an analysis is carried out of the consciousness, satisfaction and requirements of the residents, as respondents in the questionnaire, related to the master room. and Research is then conducted of the architectural methods for planning the master room. Finally, future countermeasures for planning the master room are described based on the above analysis and research findings.

Lesson Plan Development Based on Marjorie M. Brown’s Home Economics Curriculum Paradiam in Area of Human Development and Family Relationship (Morjorie M. Brown의 가정과 교과과정 모형에 근거한 ‘인간발달과 가족관계’ 영역의 학습지도안 개발)

  • 장혜경;유태명
    • Journal of Korean Home Economics Education Association
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    • v.6 no.2
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    • pp.109-131
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    • 1994
  • This study developed and proposed a lesson plan for the area of “Human development and family relationship”in secondary home economics curriculum. In current educational practice in secondary home economics curriculum, the employed goal and the nature of home economics are neither stated specifically nor closely interrelated. This problem has led us not being able to achieve pursuing goal of home economics education and to employ appropriate teaching methods. In view of this situation, the purpose of this study was to propose a lesson plan reflecting the contents and teaching methods to overcome difficulties and inefficiency in the current practice of secondary home economics education. The theoretical background of the lesson plan was based on the Marjorie M. Brown’s philosophy of home economics which can be summerized as follows: 1. The goal of home economics is to help individuals and families to become autonomous in their own family life and to be more capable of interacting with others in behalf of well-being of the family and of social evolution toward a free society. 2. The characteristics of home economics is conceptualized as practical science and personal service profession. 3. the nature of problems which home economics should deal with is perennial and practial. 4. Practial reasoning composed of historical understanding, critical action, and reflective thinking is appropriate for the previously mentioned goal and characteristics of home economics and for dealing with perennial practial problems. The lesson plan was proposed for one of perennial problem, “How should we understand, create, and maintain our family culture\ulcorner”by employing practial reasoning and teaching models such as “role play”and “classroom meeting.”

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The Proposal for Improvement of Legal System for the Persons with Disabilities (장애인복지 관련 법제의 발전방향)

  • Woo, Jooh-Hyung
    • Journal of Legislation Research
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    • no.41
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    • pp.125-170
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    • 2011
  • In Korea, the evolution of welfare for people with disabilities can be divided largely four stages. The first phase is before 1981, the second is from 1981 to 1988, the third is from 1989 to 2006 and the fourth phase is from 2007 to now. In the first phase people with disabilities were considered as ones of charity. In the second period the welfare ideal for people with disabilities was appeared. In the third, the framework of welfare system for people with disabilities was formed and welfare services began to be expanded. The fourth phase has been the time to secure human right and social services for people with disabilities. In Korea, for people with disabilities, 2007 was the year of historical turning point. "The Act of Prohibition on Disability Discrimination and Remedy for Right"was built that year and became effective the next year. Also "The Special Education Act for People with disabilities" was enacted newly. "The Disabled Welfare Act" was amended for the change of welfare paradigm. The change is introduction of Independent Living. After 2007 Korean legal systems for people with disabilities have been improved largely.