• Journal of Wetlands Research
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• v.24 no.1
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• pp.1-24
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• 2022

This study was conducted to perform efficient conservation and management by classifying the types of wetlands distributed in forests of Korea and assigning grades according to the evaluation system from 2015 until 2019. From 2005 to 2014, 1,264 sites derived from the first national forest wetland survey and 16 additional excavated sites were classified and also evaluated 455 out of a total of 1,280 forest wetlands. Forest wetlands are divided into four types: natural type, abandoned paddy field type, man-made type, and modified type, and by reclassifying them in detail, a total of 11 detailed wetland types could be distinguished. Based on this, evaluation was performed according to various items such as plants and ecology, hydrology and hydrology, humanities and society, and the degree of disturbance was graded. As a result, the forest wetland value was sorted at 30 A- grade sites, high-value B-grade 201 sites, moderate C-grade 184 sites, and low-value D-grade 40 sites. Forest Genetic Resource Reserve (FGRR) and other effective area -based conservation measures (OECMs) were designated for 231 sites that received a high grade of A or B, and a long-term monitoring system should be established to systematically conserve forest biodiversity hotspot. It is judged that wetlands need to be managed more effectively and at the national level.

• The Plant Pathology Journal
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• v.40 no.1
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• pp.48-58
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• 2024

The oldest and most extensively cultivated form of millet, known as pearl millet (Pennisetum glaucum (L.) R. Br. Syn. Pennisetum americanum (L.) Leeke), is raised over 312.00 lakh hectares in Asian and African countries. India is regarded as the significant hotspot for pearl millet diversity. In the Indian state of Haryana, where pearl millet is grown, a new and catastrophic bacterial disease known as stem rot of pearl millet spurred by the bacterium Klebsiella aerogenes (formerly Enterobacter) was first observed during fall 2018. The disease appears in form of small to long streaks on leaves, lesions on stem, and slimy rot appearance of stem. The associated bacterium showed close resemblance to Klebsiella aerogenes that was confirmed by a molecular evaluation based on 16S rDNA and gyrA gene nucleotide sequences. The isolates were also identified to be Klebsiella aerogenes based on biochemical assays, where Klebsiella isolates differed in D-trehalose and succinate alkalisation tests. During fall 2021-2023, the disease has spread all the pearl millet-growing districts of the state, extending up to 70% disease incidence in the affected fields. The disease is causing considering grain as well as fodder losses. The proposed scale, consisting of six levels (0-5), is developed where scores 0, 1, 2, 3, 4, and 5 have been categorized as highly resistant, resistant, moderately resistant, moderately susceptible, susceptible, and highly susceptible disease reaction, respectively. The disease cycle, survival of pathogen, and possible losses have also been studied to understand other features of the disease.

• Fisheries and Aquatic Sciences
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• v.27 no.3
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• pp.145-158
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• 2024

Life history characteristics, habitat landscape, and historical events are believed to have shaped the patterns of genetic variation in many taxa. The bony lip barb, Osteohilus vittatus, represent a potamodromous fish that complete all life cycle in freshwater and is widely distributed in Southeast Asia. It usually lives in small rivers and other freshwater habitats, and movement between habitats for either food or reproduction has been typical. These life history characteristics may promote gene flow, leading to less structured populations. However, many freshwater habitats are fragmented, which restricts gene flow. We investigate how this interplay has shaped patterns of genetic variation and phylogeographic structure within this species in the Sundaland, a biodiversity hotspot with a complex geological history, using mitochondrial cytochrome oxidase I (mtCOI) as a genetic marker. Forty-six mtCOI sequences of 506 bp long were collected from ten localities, eight geographically isolated and two connected. The sequences were used for population genetic and phylogeographic analyses. Our results showed a low genetic diversity within populations but high between populations. There was a deep phylogeographic structure among geographically isolated populations but a lack of such structure in the connected habitats. Among geographically isolated populations, sequence divergence was revealed, ranging from 1.8% between Java and Sumatra populations to 12.2% between Malaysia and Vietnam. An indication of structuring was also observed among localities that are geographically closer but without connectivity. We conclude that despite high dispersal capacity, the joint effects of historical events, long-term geographic isolation associated with sea level oscillation during the Pleistocene, and restricted gene flow related to lack of habitat connectivity have shaped the phylogeographic structure within the O. vittatus over the Sundaland.

• Information Systems Review
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• v.20 no.2
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• pp.63-85
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• 2018

Emerging hotspot and trendy areas are formed into alleys and blocks with the help of viral effects among social network services (SNS) users called "Golmogleo." These users search for every corner of the alleys to share and promote their own favorite places through SNS. An analysis of hot places is limited if it is only based on macroeconomic indicators such as commercial area data published by national organizations, large-scale visiting facilities, and commuter figures. Careful analyses based on consumers' actual activities are needed. This study develops a "social big data analysis methodology" using Instagram data, which is one of the most popular SNSs suitable to identify recent consumer trends. We build a spatial analysis model using Local Moran's I. Results show that our model identifies new trend zones on the basis of posting data in Instagram, which are not included in the commercial information prepared by national organizations. The proposed analysis methodology enables better identification of the latest trend areas formulated by SNS user activities. It also provides practical information for start-ups, small business owners, and alley merchants for marketing purposes. This analytical methodology can be applied to future studies on social big data analysis.

• International Journal of Stem Cells
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• v.16 no.2
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• pp.180-190
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• 2023

Background and Objectives: Regenerative endodontic procedures (REPs) are a research hotspot in the endodontic field. One of the biggest problems of REPs is that it is difficult to realize regeneration of pulp-dentin complex and functional reconstruction. The reason is still not clear. We hypothesize that the migration may be different in different dental stem cells. Periodontal ligament stem cells (PDLSCs) may migrate faster than stem cells of apical papilla (SCAPs), differentiating into cementum-like tissue, bone-like tissue and periodontal ligament-like tissue and, finally affecting the outcomes of REPs. Hence, this study aimed to explore the mechanism that regulates the migration of PDLSCs. Methods and Results: After isolating and culturing PDLSCs and SCAPs from human third molars, we compared the migration of PDLSCs and SCAPs. Then we investigated the role of SDF-1𝛼-CXCR4/CXCR7 axis in PDLSC migration. We further investigated the impact of Porphyromonas gingivalis (P. gingivalis) lipopolysaccharide (LPS) on PDLSC migration and the potential mechanism. PDLSCs showed better migration under both noninflammatory and inflammatory conditions than SCAPs. SDF-1𝛼 can promote the migration of PDLSCs by elevating the expression of CXCR4 and CXCR7, increasing the interaction between them, promoting expression of 𝛽-arrestin1 and activating the ERK signaling pathway. P. gingivalis LPS can promote the migration of PDLSCs toward SDF-1𝛼 through increasing the expression of CXCR4 via the NF-𝜅B signaling pathway, promoting the expression of 𝛽-arrestin1, and activating the ERK signaling pathway. Conclusions: This study helped elucidate the potential reason for the difficulty in forming pulp-dentin complex.

• Journal of the Korean Association of Geographic Information Studies
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• v.27 no.3
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• pp.99-114
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• 2024

Recently, the concept of neighborhood unit plan has been receiving attention due to expectations of balanced development and sustainable development through resolving regional gaps and reflecting regional characteristics. Accessibility to essential living facilities that can support daily life is considered an important factor in neighborhood unit plan. Therefore, this study analyzed accessibility from facilities based on the living facilities and access range set in the neighborhood unit plan, and analyzed spatial accessibility inequality in connection with the neighborhood unit plan and spatial clustering. As a result of analyzing accessibility in Busan Metropolitan City, various accessibility ranges were found depending on the facility. In addition, as a result of analyzing in connection with spatial clustering, regional inequality was found, such as hotspot areas in Gangdong, old downtown, Dongrae, and Haeundae, and coldspot areas in Gangseo and Gijang, and spatial inequality was found in which hotspots and coldspots exist simultaneously within the same neighborhood unit. Considering these spatial characteristics, detailed planning and policy establishment are necessary for facilities lacking in small-size neighborhood units, and the results of the analysis are expected to be meaningful in realizing the urban policy of balanced development that has been recently promoted.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.18 no.1
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• pp.51-62
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• 2020

This study was conducted to develop a method for depth assessment of embedded sources using gamma-spectrum ratio and for the evaluation of field applicability. To this end, Peak to Compton and Peak to valley ratio changes were evaluated according to ¹³⁷Cs, ⁶⁰Co, ¹⁵²Eu point source depth using HPGe detector and MCNP simulation. The effects of measurement distance of PTV and PTC methods were evaluated. Using the results, the source depth assessment equation using the PTC and PTV methods was derived based on the detection distance of 50 cm. In addition, the sensitivity of detection distance changes was assessed when using PTV and PTC methods, and error increased by 3 to 4 cm when detection distance decreased by 20 cm based on 50 cm. However, it was confirmed that if the detection distance was increased to 100 cm, the effects of detection distance were small. And PTV and PTC methods were compared with the two distance measurement method which evaluates the depth of source by the change of net peak counting rate according to the detection distance. As a result of source depth assessment, the PTV and PTC showed a maximum error of 1.87 cm and the two distance measurement method showed maximum error of 2.69 cm. The results of the experiment confirmed that the accuracy of the PTV and PTC methods was higher than two distance measurement. In addition, Sensitivity evaluation by horizontal position error of source has maximum error of less than 25.59 cm for the two distance measurement method. On the other hand, PTV and PTC method showed high accuracy with maximum error of less than 8.04 cm. In addition, the PTC method has lowest standard deviation for the same time measurement, which is expected to enable rapid measurement.

• Tuberculosis and Respiratory Diseases
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• v.58 no.1
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• pp.11-17
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• 2005

Background : Interferon-gamma ($IFN-{\gamma}$) is essential in the immune response to mycobacterial infections, and a complete or partial deficiency in the $IFN-{\gamma}$ receptor 1 ($IFN{\gamma}R1$) or the $IFN-{\gamma}$ receptor 2 ($IFN{\gamma}R2$) have been reported to confer susceptibility to a disseminated infection with nontuberculous mycobacteria. However, similar mutations in the $IFN-{\gamma}$ receptor have not been specifically examined in the patients with clinical tuberculosis. Methods : This study searched for mutations in the $IFN-{\gamma}$ receptor gene that resulted in a partial $IFN-{\gamma}$ receptor deficiency in six patients with disseminated tuberculosis. The previously identified $IFN{\gamma}R1$ and $IFN{\gamma}R2$ coding regions were sequenced after amplification. Results : There was no partial $IFN{\gamma}R1$ deficiency including a homozygous recessive missense mutation causing an amino-acid substitution in the extracellular domain of the receptor (I87T) and a hotspot for small deletions (818delT, 818del4, 818insA) found in any of the patients. In addition, a partial $IFN{\gamma}R2$ deficiency of the homozygous missense mutation (R114C) was not found in any of the patients. Conclusion : Genetic defects causing a partial $IFN-{\gamma}$ receptor deficiency were not identified in our patients with disseminated tuberculosis.

• Journal of the Korean Society of Marine Environment & Safety
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• v.27 no.2
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• pp.387-393
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• 2021

In this study, finite element analysis was performed to evaluate a method of increasing the fatigue life of the pipe connection structure commonly used in the topside structure of offshore platforms. MSC Patran/Nastran, a commercial analysis program, was used, and the critical structural model was selected from the global analysis. To realize the stress concentration phenomenon according to the load, modeling using 8-node solid elements was implemented. The main loads were considered to be two lateral loads and a tensile load on a diagonal pipe. To check the hotspot stress at the main location, a 0.01 mm dummy shell element was applied. After calculating the main stress at the 0.5-t and 1.5-t locations, the stress generated in the weld was estimated through extrapolation. In some sections, this stress was observed to be below the fatigue life that should be satisfied, and reinforcement was required. For reinforcement, a bracket was added to reduce the stress concentration factor where the fatigue life was insufficient without changing the thickness or diameter of the previously designed pipe. Regarding the tensile load, the stress in the bracket toe increased by 23 %, whereas the stress inside and outside of the pipe, which was a problem, decreased by approximately 8 %. Regarding the flexural load, the stress at the bracket toe increased by 3 %, whereas the stress inside and outside of the pipe, which was also a problem, decreased by approximately 48 %. Owing to the new bracket reinforcement, the stress in the bracket toe increased, but the S-N curve itself was better than that of the pipe joint, so it was not a significant problem. The improvement method of fatigue life is expected to be useful; it can efficiently increase the fatigue life while minimizing changes to the initial design.

• Economic and Environmental Geology
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• v.57 no.1
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• pp.1-15
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• 2024

The Melanesian region in the western Pacific is dominated by complex plate tectonics, with the largest oceanic plateau, the OntongJava plateau, and a hotspot, the Caroline Islands. To better understand the complex geodynamics of the region, we estimate P- and S-velocity models and 𝛿 (V_P/V_S) model by using relative teleseismic travel times measured at seismometers on land and the seafloor. Our results show high-velocity anomalies in the subduction zones of the Melanesian region to a depth of about 400 km, which is thought to be subducting Solomon Sea, Bismarck, and Australian plates along plate boundaries. Along subduction zones, positive 𝛿 (V_P/V_S) anomalies are found, which may be caused by partial melting due to dehydration. A broad high-velocity anomaly is observed at 600 km depth below the Ontong-Java plateau, with a negative 𝛿 (V_P/V_S) anomaly. This is thought to be a viscous and dry remnant of the Pacific plate that subducted at 45-25 Ma, with a low volume of fluids due to dehydration for a long period in the mantle transition zone. Beneath the Caroline Islands, a strong low-velocity anomaly is obseved to a depth of 800 km and appears to be connected to the underside of the remnant Pacific plate in the mantle transition zone. This suggests that the mantle plume originating in the lower mantle has been redirected due to the interaction with the remnant Pacific plate and has reached its current location. The mantle plume also has a positive 𝛿 (V_P/V_S) anomaly, which is thought to be due to the influence of embedded fluids or partial melting. A high-velocity anomaly, interpreted as an effect of the thick lithosphere beneath the Ontong-Java plateau, is observed down to 300 km depth with a negative 𝛿 (V_P/V_S) anomaly, which likely indicate that little fluid remains in the melt residue accumulated in the lithosphere.