• 한국산학기술학회논문지
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• 제18권6호
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• pp.459-463
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• 2017

대부분의 용용융아연도금 설비는 오픈된 공간에서 용융된 아연을 사용하고 있기 때문에 용융된 아연의 용탕에서 발생되는 고온, Zn Fume 등에 의한 산화가 발생되고 있다. 현재 설비에 사용되고 있는 소재는 SM45C(기계구조용 탄소강, KS규격)으로 사용되고 있다. Zn Fume이 집중적으로 발생되고 있는 부분의 설비를 부분적으로 고온, Zn Fume에 강한 재료를 사용한다면 설비의 수명과 성능향상에 도움이 될 것으로 예상된다. 따라서 본 연구에서는 직접 설계한 Ni 합금과 Inconel 합금을 직접 고온, Zn Fume 환경에서 산화 시켜 각각의 부식성을 확인하여 비교 분석하였으며, 용융아연도금에 사용되는 용탕의 종류를 나누어 용탕에 따른 각 합금의 부식성 등을 확인하여 보았다. 500~700도로 내에 Zn, Al-Zn 용탕을 두고 Ar 가스를 이용하여 용탕에서 직접 버블링하여 Zn fumef를 발생시켜 고온, Zn fume에 의해 강제 부식을 행하는 실험을 하였다. 30일 후의 sample들을 꺼내어 표면의 산화층을 광학현미경, SEM으로 확인하고, 동전위분극 시험을 이용하여 부식성을 분석하였으며, 부식성은 용탕의 종류에 따라 달라지는 모습을 보였다.

• 대한의생명과학회지
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• 제14권2호
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• pp.97-103
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• 2008

This study was conducted to investigate the effect of an anti-inflammatory and analgesic action of the glucosamine HCl (Glucosamine) and SH-1 (Glucosamine + Oriental herbal composition combined group). Male sprague-Dawley rats $(200{\sim}250g)$ and ICR mice $(20{\sim}30g)$ were randomized and these experimental groups were divided into 4 groups. Two control group were given as negative control (saline) and positive control (Ibuprofen, 100 mg/kg) and two groups given as oral administration of Glucosamine (320 m/kg) and SH-1. Carrageenan induced paw edema test, hot plate method, croton oil induced granuloma, capillary permeability test and acetic acid writhing syndrome were also shown to be comparable in the SH-1 group to anti-inflammatory drug group such as positive control group (Ibuprofen). Although further studies should be performed to confirm the effects of SH-1, present results suggest that the combined administration of SH-1 have potential action in anti-inflammatory and analgesic action. It could be applicable for the improvement of arthritic symptoms as a new diet-supplement.

• KSBB Journal
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• 제15권4호
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• pp.331-336
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• 2000

여름과 가을에 수확한 연진쑥을 열수 빛 에탄올로 추출하 여 B(a)P의 변이원성에 대한 억제효과를 SOS Chromotest로 시험한 결과 여름에 수확한 시료의 물 추출물에서 강한 억제 효과를 나타내었다. 따라서 에탄올 가용성 분획과 불용성 분 획으로 분리하였으며 분획별 돌연변이 억제효과는 불용성 분 획에서 더 높게 나타났다. 불용성 분획은 SOS Chromotest외 A Ames test에서 정확한 용량의존성 억제효과를 나타내었고, 50% 돌연변이 억제농도 $(IC_{50}$는 E. coli PQ37에 대하여는 $200{\mu}g/assay$, S. typhimurium TA98에 대하여는 $800{\mu}b/plate$ TAIOO에서는 $600{\mu}g/plate$이었다. 그러나 세포내.외 항돌연변이 효과를 비교한 결과 세포내 항돌연변이 효과는 나타내지 않았다 따라서 인진쑥 물 추출물의 돌연변이 억제효과는 d desmutagenic effect에 의한 것으로 확인되었다 HPLC를 사용 하여, B(a)P의 변이원성에 주된 효소인 cytochrome P-4S0 1A1에 의해 대사되어지는 aflatoxin Mj 농도를 측정한 결 과 AFM1의 형성이 크게 감소되었다. B(a)P의 변이원성에 대 한 인진쑥 불추출물의 항돌연변이 효과는 아마도 B(a)P를 ultimate mutagen으로 대사시키는 cytochrome P-4S0 1A1 효소계를 저해하여 나타나는 것으로 해석된다.

• 한국조리학회지
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• 제19권3호
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• pp.73-86
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• 2013

본 연구에서는 우리나라에서 많이 재배되고 섭취량이 많은 들깻잎을 생면에 첨가를 하여 식품으로서의 이용가치와 최적의 생면 레시피를 도출하고자 열풍건조 들깻잎을 제조하여 밀가루 대비 0%, 3%, 6%, 9%, 12%를 각각 첨가하였다. 반죽의 수분은 0%첨가한 대조군이 34.41%로 가장 높게 나타냈으며, pH는 12%를 첨가한 반죽이 5.59로 가장 낮은 수치를 나타냈다. 반죽의 L값과 a값은 0% 첨가군이 가장 큰 값을 보였으며, b값은 첨가량이 증가할수록 감소하였다. 반죽의 WRC 분석결과는 첨가량이 많아질수록 수분흡수력이 증가하였다. 생면의 수분함량은 0%첨가한 대조군이 가장 낮았으며, pH는 대조군이 가장 높게 나타났다. 생면의 L, a, b값은 0% 첨가군이 각각 가장 높은 값을 나타냈다. 중량과 부피는 0% 첨가군이 가장 큰 값을 나타났고, 탁도의 경우 열풍건조한 들깻잎의 첨가량이 증가 할수록 탁도가 증가한 경향을 보였다. 경도(Hardness)와 응집성(Cohesiveness)은 는 0% 첨가군이 가장 낮게 나타났고, 탄력성(Springiness)은 열풍건조 들깻잎의 첨가량이 증가 할수록 감소하는 경향을 보였으며, 생면의 미생물 변화는 저장 2일과 3일째에는 시료의 첨가량에 따라서 월등히 감소하는 경향을 보였다. 관능검사의 결과에서 외관(Appearance), 향(Flavor), 색(Color), 맛(Taste), 조직감(Texture) 모든 항목에서 6% 첨가군이 가장 높았다. 전체적인 기호도(Overall acceptability) 역시 6% 첨가군이 7.20로 가장 높았고, 12% 첨가가 3.27로 가장 낮게 나타났다. 이와 같은 결과를 종합허여 볼 때 열풍건조한 깻잎 분말을 첨가를 하여 생면을 제조시에는 저장성과 관련된 부분에서는 첨가량이 많아질수록 미생물 억제작용이 증가하나, 관능적 측면에서는 6% 첨가시에 가장 우수한 것으로 나타났다.

• 한국동물위생학회지
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• 제34권2호
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• pp.159-166
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• 2011

This study was carried out to develope enzyme-linked immunosorbent assay (ELISA) for detection of canine brucellosis in dogs experimentally inoculated with Brucella abortus 1119-3 and B. canis RM666. Groups A, B and C of dogs (each group consisting of three dogs) were orally inoculated with approximately $5{\times}10^9$ colony-forming units of B. abortus and B. canis, and with sterile pyrogen-free PBS, respectively. The animals were monitored at regular intervals upto the 12th week post inoculation (PI) by standard tube agglutination test (STAT), plate agglutination test (PAT), Rose Bengal test (RBT), 2-mercaptoethanol rapid slide agglutination test (2ME-RSAT) and ELISA. The induced antibody titers in group A dogs were detected from the first week PI to the eighth week PI in STAT, PAT and RBT using the inactivated whole cells of B. abortus 1119-3 as antigens, while no sera in groups B and C dogs reacted with the antigens. In 2ME-RSAT using whole cells of B. canis M-strain as antigens, the induced antibody titers in group B dogs were observed at the second week PI and persisted for the 12th week PI, while sera of groups A and C dogs did not react with the whole cells. In ELISA using cytoplasmic fractions antigen of B. abortus 1119-3, the mean optical density of antibodies in groups A and B was detected from the first and second weeks PI, respectively, and persisted for 12th week PI, while sera of group C did not cross-react with the fractions antigen. However, in ELISA using the hot saline extracts of B. canis M- as an antigen, the induced antibody titers in only group B dogs were detected from second week PI and persisted for until the end of this study. These results indicate that the ELISA using B. abortus 1119-3 cytoplasmic fractions as antigens can be a good candidate for detection of brucellosis by B. abortus as well as B. canis in dogs.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2005년도 제24회 춘계학술대회논문집
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• pp.305-308
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• 2005

본 논문은 30ton급 액체로켓엔진 연소기의 연소시험 검증용 제작에 관한 것이다. 기본설계와 상세설계를 통해 도면을 작성하고, 이에 따라 제작하였다. 연소기는 크게 헤드부와 챔버부로 구성되며, 챔버는 KSR-III에 적용되었던 내열재 챔버와 재생 냉각 방식의 챔버를 제작하였다. 연소기 헤드는 저온 특성이 좋은 SUS316L 재료를 사용하였다. 내열재 챔버는 내부는 silica/phenolic 재료를 사용하였고, 외부케이스는 SUS316L을 적용하였고, 재생 냉각 챔버는 C18200과 SUS316L 재료를 사용하였다. 선반 가공, 일반 밀링 가공, MCT 가공등의 기계적 가공을 한 후 전해 연마를 통해 이물질을 제거 하였다. 분사기와 분사기 플레이트의 접합과 재생 냉각 챔버 등 일부 부품의 접합은 구조적인 특성으로 인해 브레이징 기법을 적용하였다.

• Advances in Traditional Medicine
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• 제8권3호
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• pp.243-251
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• 2008

The effect of alcoholic extracts of Costus specious (Family: Zingiberaceae) was evaluated in experimental models of pain and inflammation. Oral administration of 100, 200 and 300 mg/kg of C. specious extracts were used for the above study. Crude extracts of C. specious (300 mg/kg dose) showed maximum time needed for the response against thermal stimuli ($7.242\;{\pm}\;0.532\;s$) which is comparable to diclofenac sodium ($8.471\;{\pm}\;0.25\;s$) in the hot plate test. The MPH (Maximum Possible Analgesia) has been found to be 14.285 for 300 mg/kg dose of the crude extract while the MPH for diclofenac was 15.857 after 60 min of administration in the hot tail-flick method. The crude extract at 300 and 200 mg/kg doses showed significant reduction in acetic acid induced writhings in mice with a maximum effect of 59.661% reduction at 300 mg/kg dose which is comparable to standard diclofenac sodium (73.4%). Alcoholic extract of C. specious showed significant inhibition in serotonin and egg albumin induced hind paw oedema in rats at 100, 200 and 300 mg/kg of the crude extracts respectively (Serotonin induced edema 44.22; 53.75; 58.51%; egg albumin induced edema - 41.317; 53.892; 59.880% inhibition after 4 h respectively). The antiinflammatory effects showed by the extract were comparable to that of standard indomethacin 5 mg/kg (Serotonin induced edema 77.56%; egg albumin induced edema 77.844% inhibition after 4 h). These results suggest that the extract possesses both the anti-inflammatory and analgesic activity on mice and rat model.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 추계학술대회논문집B
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• pp.341-346
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• 2001

The gun-type gas burner adopted in this study is generally composed of some slits and swirl vanes. Therefore, this paper is studied to investigate the effect of slits and swirl vanes on the turbulent flow fields in the horizontal plane of gas swirl burner with a cone type baffle plate measured by using X-probe from hot-wire anemometer system. This experiment is carried out at flow rate $450\;{\ell}/min$, which is equivalent to the combustion air flow rate necessary for heat release 15,000 kcal/hr in gas furnace, in the test section of subsonic wind tunnel. When the burner has only swirl vanes, the axial mean velocity component shows the characteristic that spreads more remarkably toward radial direction than axial one, but when it has only slits, that is developed spreading more toward axial direction than radial one. Therefore, because the biggest speed is spurted in slits and it derive main flow toward axial direction encircling rotational flow that comes out from swirl vane that is situated on the inside of slits, both slits and swirl vanes composing of cone type gas burner act role that decreases the speed near slits and increases the flow speed in the central part of a burner. Moreover, because rotational flow by swirl vanes and fast jet flow by slits increase turbulent intensities effectively coexisting, the turbulent kinetic energy is distributed with a bigger size fairly near slits than burner models which have only slit or swirl vanes within X/R<0.6410.

• 동력기계공학회지
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• 제5권2호
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• pp.22-29
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• 2001

This paper represents axial mean velocity, turbulent kinetic energy and swirl number based on momentum flux measured in the X-Y plane and Y-Z plane respectively of a cone type gas swirl burner by using X-probe from the hot-wire anemometer system. This experiment is carried out at flow rates 350 and $450{\ell}/min$ respectively, which are equivalent to the combustion air flow rate necessary for heat release 15,000 kcal/hr in gas furnace, in the test section of a subsonic wind tunnel. Axial mean velocities and turbulent kinetic energies show that their maximum values exist centering around narrow slits situated radially on the edge of and in the forefront of a burner until $X/R{\fallingdotseq}1.5$, but they have a peculiar shape like a starfish diffusing and developing into inward and outward of a burner by means of the mixing between flows ejected from narrow slits, an inclination baffle plate and swirl vanes respectively according to downstream regions. Moreover, they show a relatively large value in the inner region of 0.5$S_m$ obtained by integration of velocity profiles shows a characteristic that has an inflection point composing of the maximum and minimum value until X/R<3, but shows close agreement with the geometric swirl number after a distance of X/R=3.

• 대한기계학회논문집B
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• 제25권2호
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• pp.225-234
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• 2001

This paper represents the vector fields, three dimensional mean velocities, the turbulent intensities, the turbulent kinetic energy, and the Reynolds shear stresses in the X-Y plane of gas swirl burner with a cone type baffle plate measured by using X-probe from hot-wire anemometer system. This experiment is carried out at flow rates 350 and 450ℓ/min respectively, which are equivalent to the combustion air flow rate necessary for heat release 15,000 kcal/hr in gas furnace, in the test section of subsonic wind tunnel. The vector plot shows that the maximum axial mean velocity component exists in the narrow slits situated radially on the edge of gas swirl burner, for that reason, there is some entrainment phenomena of ambient air in the outer region of burner. Moreover, mean velocities in the initial region are largely distributed near the outer region of burner at Y/R≒0.97, but they diffuse and develop into the center flow region of burner according to the increase of axial distance. The turbulent intensities and the turbulent kinetic energy due to large inclination of mean velocity and swirl effect show that the maximum value in the initial region of burner is formed in the narrow slits situated radially on the edge of gas swirl burner and large values are mainly formed in the entire region of burner after X/R=2.4358, hence, the combustion reaction is anticipated to occur actively near this region. And the Reynolds shear stresses are also largely distributed from slite to vanes of gas swirl burner in the intial region, but their values largely disappear after X/R=3.2052.