• Journal of Nutrition and Health
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• 제36권1호
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• pp.18-23
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• 2003

We studied the effects of hot water extract of Inonotus obliquos mushroom on the proliferation and apoptosis of the human colon adenocarcinoma, HT-29 and the human stomach adenocarcinoma, SNU-484 cell. Cells were maintained with Dulbecco's modified Eagle medium/Ham's F-12 nutrient mixture supplemented with 10% fetal bovine serum at 37$^{\circ}C$ in a humidified $CO_2$. For the cell proliferation experiments, cells were seeded in 35 mm dishes, and were treated with the various concentrations of the extract for the different time course. Apoptosis was measured by caspase-3 activity. When we incubated HT-29 cells for 24, 48, 72, and 96 hours after treatments, the cell proliferation was more suppressed with more treatment time. In case of the human stomach cancer cell, SNU484, the extract significantly decreased the cell number. Thus, the treatment of 1.5 mg/$m\ell$ extract decreased almost half of the cell number. Caspase-3 activity in HT-29 was increased by the treatment of mushroom extracts. In SNU484, caspase-3 activity tended to increase in proportion to the amounts of the extracts and the treatment of Inonotus obliquos affected the activity a lot. Therefore, Inonotus obliquos is suggested for the prevention of gastro-intestinal cancer and strongly recommended for the treatment of stomach cancer. (Korean J Nutrition 36(1) : 18~23, 2003)

• 한국식품과학회지
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• 제30권2호
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• pp.391-396
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• 1998

핫소스의 수입을 억제하고 우리 기호에 적합한 한국식 핫소스를 개발하기 위하여 생홍고추를 이용한 한국식 핫소스의 제조방법을 조사하였다. 개발 대상으로 선정한 Tabasco hot sauce의 일반성분을 분석한 결과 수분은 95.66% (w/w), 염도 2.79% (w/w), 적정산도 3.62% (w/w), 조섬유 0.42% (w/w), 환원당 0.03% (w/w), capsanthin 0.89% (w/w), capsaicin 4.28 mg%, pH 3.26이었다. 생홍고추를 oak통에 담아 $10^{\circ}C$에서 12개월간 숙성시켜 제조한 한국식 핫소스의 일반성분을 분석한 결과 수분은 92.05% (w/w), 염도 8.82% (w/w), 적정산도 3.88% (w/w), 조섬유 3.14% (w/w), 환원당 1.78% (w/w), capsanthin 0.13% (w/w), capsaicin 2.32mg%, pH 3.29이었다. Capsaicin과 capsanthin을 제외한 환원당, 염도, 조섬유의 함량이 수입 핫소스보다 많은 편이었다. 12개월 숙성기간 동안 일반성분은 큰 변화를 보이지 않았으나 젖산균과 효모는 숙성 초기부터 숙성 3개월까지 급속히 증가하고 이후 완만히 증가하다가 숙성 8개월부터 감소하는 경향을 나타내고 있었다. 한국식 핫소스와 수입 핫소스에 대하여 맛, 향, 색 및 전체적인 기호도에 대하여 관능검사를 실시한 결과 한국식 핫소스가 수입 핫소스보다 기호도에서 우수한 것으로 나타났다.

• 제어로봇시스템학회논문지
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• 제13권10호
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• pp.940-948
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• 2007

The Advanced Spent Fuel Conditioning Process(ACP), which is the process of the reduction of uranium oxide by lithium metal in a high temperature molten salt bath for spent fuel, was developed at Korea Atomic Energy Research Institute (KAERI). Since the ACP equipment is located in an intense radiation field (hot cell) as well as in a high temperature, it must be remotely operated and maintained. The ACP hot cell is very narrow so the workspace of the wall-mounted mechanical Master-Slave Manipulators(MSMs) is restricted. A Bridge Transported Servo Manipulator(BTSM) system has been developed to overcome the limitation of an access that is a drawback of the mechanical MSMs. The BTSM system consists ot a bridge crane with telescoping tubeset, a slave manipulator, a master manipulator, and a control system. We applied a bilateral position-position control scheme with friction compensation as force-reflecting controller. In this paper, the transmission characteristics on the tendon-and-pulley train is numerically formulated and analyzed. Also, we evaluate the performance of the force-reflecting servo manipulator.

• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2004년도 학술논문집
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• pp.278-284
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• 2004

전해환원공정에서 발생하는 금속전환체와 용융염을 각각 smelting하고 고화시키는 공정을 개발하였다. 진공조건에서 다단계 가열에 의하여 마그네시아 용기에 담긴 금속전환체를 잔류 용융염과 분리하고 용융시켜 금속 잉곳을 제조하는 운전방법을 제시하는 한편, 금속전환체의 분석을 수행하였다. 전해환원 공정에서 감압이송된 용융염의 경우에는 이송과 계량에 적합하게 이중 용기와 염밸브를 사용하여 일정 형상과 크기로 고화하는 신개념을 도출하였다. 본 연구의 결과는 한국원자력연구소 Advanced Spent Fuel Conditioning Process의 hot cell 실증시스템 설계에 적용되었다.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.1715-1718
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• 2005

During demonstrations of a process conditioning spent nuclear fuels, it may be necessary to transport and handle Spent fuel road cuts from Post Irradiation Examination facility to Slitting device in The hot cell. It may be not easy to transport spent fuel rod cuts because rod cuts are high radioactive materials. For this purpose, we have developed a capsule for transporting and handling high radioactive materials. We have analyzed conditions of a hot cell and requirements of the device, designed and manufactured The prototype of the device, and done some performance tests. From the tests, it has been shown that transportation and handling without scattering nuclear material was smooth but the weight of capsule was heavy. These result will be reflected to a design of the improved transportation and handling device which will be used during demonstrations.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 춘계학술대회 논문집
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• pp.684-687
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• 2002

The authors have developed two devices which cuts the spend fuel rod to an optimal size and extracts fuel pellet from the pieces of cut fuel rods. These devices are so important to reduce radioactive wastes that some advanced countries developed their own methods and devices. The authors have benchmarked from these methods and devices. For spent fuel rod cutting, the tube cutting method has been chosen. some mechanical properties of the fuel tube and pellet has been carefully considered for an optimal cutting size. For fuel pellet extraction, a mechanically extracting method has been adopted. The existing chemical method have turned out to be inappropriate because it produced large amount of radioactive wastes, in spite of its high fuel recovery characteristics. The developed method has an advantage that it can be applied to other fuel rods that have different shapes and sizes. The two devices are set up and operated in the hot cell where people can not go in, so that the devices have been designed to be controlled remotely and modulated for easy maintenance. And the performance of the devices has been tested by using simulated fuel rod. From the experimental results, the devices are supposed to be useful for reducing radioactive wastes.

• 대한가정학회지
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• 제39권4호
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• pp.49-59
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• 2001

Natural red and yellow dyestuff was extracted from safflower (Carthamus tinctorius Linnaeus) by a new process of cellulase extraction compared with the conventional hot water extraction. Dyestuffs were extracted from safflower easily and repeatedly by means of cellulose as safflower cell wall destroyer. It means that new dyestuff extraction by cellulase improves not only yields of dyestuff from safflower successfully but also the rate of repetition of extraction. From the above experiments, the conclusions of this study were summarized as follows. 1. The optimum conditions of dyestuff extraction from safflower by general extraction method were that the solvent was the water of pH 6.0 on yellow dyestuff and 3% $K_2CO_3$ solution on red dyestuff, extraction temperature was $55^{\circ}C$, and extraction time was 30 min. 2. Among various cellulase, the NOVO cellulase was the best cell wall destroyer of safflower and finally produced the largest amount of dyestuff from safflower by cellulase extraction method. 3. The optimum conditions of dyestuff extraction by cellulase extraction method were conducted on 10 unit of cellulase per gram of safflower at $100m{\ell}$ water of pH 5.0 at $50^{\circ}C$ for 30 min.

• Biotechnology and Bioprocess Engineering:BBE
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• 제9권5호
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• pp.356-361
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• 2004

When SiHa cells were incubated for varying periods of time with extracts of PFF and PFM, the cytotoxicity of the ethanol extracts of PFF was higher than those of the other extracts. These results indicated that the extracts from fruiting bodies of p. ferulae contain antitumor Substances. When A549, SiHa and HeLa cells were incubated with different concentrations of PFF and PFM extracts, the ethanol extracts of PFF showed strong cytotoxicity against A549 tells at concentrations over $10{\mu}g/mL$ and against SiHa and HeLa cells at concentrations over $40{\mu}g/mL$. However, the differences in the cytotoxic effects of the hot water and ethanol extracts of PFM and the hot water extracts of PFF on all 3 cancer cells were not significant. Also, the PFF ethanol extracts induced synergistic effects on the TRAIL-induced apoptosis in A549 cells, which were strongly resistant to TRAIL. These results indicated that ethanol extracts of PFF were the most prominent antitumor agents toward lung cancer cells (A549).

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2004년도 추계학술대회 논문집 Vol.17
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• pp.116-119
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• 2004

In this paper, we have improved a novel (ECB) mode using tilt angle in the unique condition by hot-plate equipment. The new control of tilt angle for nematic liquid crystal (NLC) with negative and positive dielectric anisotropy on the rubbed homeotropic polyimide (PI) using baking method by Hot-plate equipment was investigated. LC tilt angle decreased with increasing baking temperature and time. Especially, the low LC tilt angle of positive type NLC $({\Delta}n>0)$ on the rubbed homeotropic PI surface by increasing temperature and time was measured. The EO characteristics of the novel ECB mode using control of tilt angle on the homeotropic surface than that of conventional OCB cell can be improved. We suggest that the developed the Novel ECB cell using control of tilt angle on the homeotropic surface is a promising technique for the achievement of a fast response time and a high contrast ratio.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 1997년도 추계학술대회 논문집
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• pp.519-522
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• 1997

In this study, the collision free path planning method of the articulated manipulator using sequential search is proposed. This method is to find the joint path of the manipulator with many degrees of freedom from the distal joint to the proximal one. To do this, the initial work space of the gantry manipulator, which is a remote maintenance equipment of the radioactive environment, is defined from the condition that the distal joint configuration is determined by the posture of maintenance. Then, 2-dimensional configuration space with the obstacle area is represented and the collision free path of manipulator is searched in the configuration space. And, this method is verified using the graphic simulation in virtual workcell for the spent fuel disassembling processes. The result of this study can be effectively used in implementing the maintenance processes for the hot cell equipment and enhance the reliability of the spent fuel management.