• Progress in Superconductivity and Cryogenics
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• v.18 no.4
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• pp.35-39
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• 2016

In recent years, high-temperature superconductor (HTS) Quadruple Triplets are being developed for heavy ion accelerators, because the HTS magnets are suitable to withstand radiation and high heat loads in the hot cell of accelerators. Generally, an iron yoke, which costs a mass of material, was employed to enhance the magnetic field when a quadrupole magnet was designed. The type of the magnet is called iron-dominated magnet, because the total magnetic field was mainly induced by the iron. However, in the HTS superconductor iron-dominated magnets, the coil-induced field also can have a certain proportion. Therefore, the air-core HTS quadrupole magnets can be considered instead of the iron-core HTS quadrupole magnet to be employed to save the iron material. This study presents the design of an air-core HTS quadruple triplet which consists three by air-core HTS quadruple magnet and compare the design result with that of an iron-core HTS quadruple triplet. First, the characteristics of an air-core HTS quadrupole magnet were analyzed to select the magnet system for the magnetic field uniformity impairment. Then, the field uniformity was improved(< 0.1%) exactly using evolution strategy (ES) method for each iron-core HTS quadrupole magnet and the air-core HTS quadruple triplet was established. Finally, the designed air-core triplet was compared with the iron-core HTS quadruple triplet, and the results of beam trajectories were presented with both the HTS quadruple triplet systems to show that the air-core triplet can be employed instead of the iron-core HTS triplet. The design of the air-core quadruple triplet was suggested for a heavy ion accelerator.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.7A
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• pp.757-767
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• 2008

Start Ongoing next generation networks are expected to be deployed over current existing networks, in the form of overlayed heterogeneous networks, in particular, in hot spot areas. Therefore, it will be necessary to develop an interworking technique such as load balancing, to achieve increased overall resource utilization in the various heterogeneous networks. In this paper, we present a new load balancing mechanism termed 'soft' load balancing where the IP(Internet Protocol) traffic of a user is divided into sub-traffic, each of which flows into a different access network. The terminology of soft load balancing involves the use of both load sharing and handover techniques. Through a numerical analysis, we obtain an optimal LBR (Load Balancing Ratio) for determining the volume of traffic delivered to each network over an overlayed multi-cell environment. Using the optimal LBR, a more reliable channel transmission can be achieved by reducing the outage probability efficiently for a given user traffic.

• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.187-190
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• 2006

In the present study, effects of tree-stream turbulence and surface trip wire on the flow past a sphere at $Re\;=\;0.4\;{\times}\;10^5\;{\sim}\;2.8\;{\times}\;10^5$ are investigated through wind tunnel experiments. Various types of grids are installed upstream of the sphere in order to change the tree-stream turbulence intensity. In the case of surface trip wire, 0.5mm and 2mm trip wires are attached from $20^{\circ}\;{\sim}\;90^{\circ}$ at $10^{\circ}$ interval along the streamwise direction. To investigate the flow around a sphere, drag measurement using a load cell, surface-pressure measurement, surface visualization using oil-flow pattern and near-wall velocity measurement using an I-type hot-wire probe are conducted. In the variation of free-stream turbulence, the critical Reynolds number decreases and drag crisis occurs earlier with increasing turbulence intensity. With increasing Reynolds number, the laminar separation point moves downstream, but the reattachment point after laminar separation and the main separation point are fixed, resulting in constant drag coefficient at each free-stream turbulence intensity. At the supercritical regime, as Reynolds number is further increased, the separation bubble is regressed but the reattachment and the main separation points are fixed. In the case of surface trip wire directly disturbing the boundary layer flow, the critical Reynolds number decreases further with trip wire located more downstream. However, the drag coefficient after drag crisis remains constant irrespective of the trip location.

• Culinary science and hospitality research
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• v.20 no.6
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• pp.190-199
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• 2014

This study was conducted to investigate the effects of the hot water extract from buckwheat (WEB) in RAW-264.7 macrophage cells against lipopolysaccharide (LPS). In these experiments, we evaluated the anti-inflammatory effects of WEB by measuring MTT assay, nitric oxide (NO), inducible NOS (iNOS) production, and cyclooxygenase-2 (COX-2) expression by Western blotting. The extracts showed a protective effect by increasing cell viability on LPS in RAW264.7 cells. WEB (0.25, 0.5, and 1.0 mg/mL) significantly suppressed LPS-stimulated production of NO. Also, WEB reduced the expression of iNOS and COX-2 proteins. The present results show that WEB has potent anti-inflammatory effects on RAW264.7 cells. In addition, WEB has various antioxidant effects as a result of 2,2'-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-Diphenyl-1-picrylhydrazyl (DPPH) which possess a radical scavenging activity. The total polyphenol and flavonoid contents of the WEB were $13.22{\pm}3.69mg\;GAE/g$ extract and $38.53{\pm}5.20mg\;CE/g$ extract respectively. The present results give the understanding of biological activities of buckwheat and encourage their application for supplements.

• BMB Reports
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• v.47 no.4
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• pp.221-226
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• 2014

Drug-resistance and imbalance of apoptotic regulation limit chemotherapy clinical application for the human hepatocellular carcinoma (HCC) treatment. The reactivation of p53 is an attractive therapeutic strategy in cancer with disrupted-p53 function. Nutlin-3, a MDM2 antagonist, has antitumor activity in various cancers. The post-translational modifications of p53 are a hot topic, but there are some controversy ideas about the function of phospho-$Ser^{392}$-p53 protein in cancer cell lines in response to Nutlin-3. Therefore, we investigated the relationship between Nutlin-3 and phospho-$Ser^{392}$-p53 protein expression levels in SMMC-7721 (wild-type TP53) and HuH-7 cells (mutant TP53). We demonstrated that Nutlin-3 induced apoptosis through down-regulation phospho-$Ser^{392}$-p53 in two HCC cells. The result suggests that inhibition of p53 phosphorylation on $Ser^{392}$ presents an alternative for HCC chemotherapy.

• Journal of Mushroom
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• v.13 no.3
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• pp.181-184
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• 2015

Mushroom have long been valued as highly nutritious and tasty foods in many societies throughout the world. It is known for biological activities including anti-inflammatory and anti-oxidative potential. However little is known about anti-cancer property. In this study, we investigated the anti-prostate cancer activity of mushrooms. For that, eight kinds of mushrooms such as, T. matsutake, S. crispa, G. lucidum-US, G. lucidum-AS, C. cardinalis-BR, G. frondosa, P. linteus, U. esculenta were extracted with hot water. Among them, three kinds of mushrooms including T. matsutake, G. lucidum-US and C. militaris-BR extracts inhibited prostate specific antigen (PSA) expression in prostate cancer cell, LNCaP. These results demonstrate that some of mushrooms inhibited PSA expression suggesting that the mushrooms might be a candidate for the treatment of prostate cancer.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.3
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• pp.301-305
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• 2012

The purpose of this study is to investigate effects of Anisi stellati Fructus Water Extract on hydrogen peroxide production in RAW 264.7 mouse macrophages. Anisi stellati Fructus were extracted by hot water. Effects of Anisi stellati Fructus water extract (AS) on hydrogen peroxide production in RAW 264.7 were measured by dihydrorhodamine 123 assay after 20, 24, 28, 44, 48, and 52 h incubation at the concentrations of 10, 25, 50, and $100{\mu}g/mL$. For 20 h incubation, AS significantly increased hydrogen peroxide production in RAW 264.7 cells by $108.6{\pm}1.56%$, $109.5{\pm}1.94%$, $108.4{\pm}1.14%$, and $107.3{\pm}3.06%$ at the concentrations of 10, 25, 50, and $100{\mu}g/mL$ (P < 0.05) respectively. For 24, 28, 44, 48, and 52 h incubation, AS also significantly increased hydrogen peroxide production in RAW 264.7 cells at the concentrations of 10, 25, 50, and $100{\mu}g/mL$ (P < 0.05). These results suggest that Anisi stellati Fructus has the immune - enhancing property related with its increase of hydrogen peroxide production in macrophages.

• Korean journal of food and cookery science
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• v.14 no.2
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• pp.195-200
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• 1998

Wheat flour and glutinous rice pastes added Kimchi were fermented at 10$^{\circ}C$ for 14 days. The numbers of total viable microorganisms and lactics were counted. Textural property by compression force and relevant changes in pectic composition were determined. Other physical properties such as color and viscosity of Kimchi juices were evaluated. Regarding the microorganism counts, the total cell counts of all Kimchi samples increased until 5th days but thereafter all decreased during fermentation. The number of lactics showed same tendency in all Kimchi samples. The compression force of control, wheat flour paste added Kimchi (WHFP-Kimchi) and glutinous rice paste added Kimchi (GLRP-Kimchi) decreased up to 72.0%, 77.0%, 66.5% respectively. During fermentation, hot water soluble pectin (HWSP) increased, whereas sodium hexametaphosphate soluble pectin (HXSP) and HCI soluble pectin (HCISP) decreased. The red chromaticity of all Kimchi juices decreased. The viscosity of all Kimchi samples decreased in the order of GLRP-Kimchi, WHFP-Kimchi and control.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.8
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• pp.1207-1213
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• 2016

Heat stress negatively affects milk quality altering its nutritive value and cheese making properties. This study aimed at assessing the impact of seasonal microclimatic conditions on milk quality of Friesian cows. The study was carried out in a dairy farm from June 2013 to May 2014 at Beni-Suef province, Egypt. Inside the barn daily ambient temperature and relative humidity were recorded and used to calculate the daily maximum temperature-humidity index (mxTHI), which was used as indicator of the degree of heat stress. The study was carried out in three periods according to the temperature-humidity index (THI) recorded: from June 2013 to September 2013 (mxTHI>78), from October 2013 to November 2013 (mxTHI 72-78) and from December 2013 to April 2014 (mxTHI<72). Eighty Friesian lactating dairy cows were monitored in each period. The three groups of cows were balanced for days in milk and parity. Milk quality data referred to somatic cell count, total coliform count (TCC), faecal coliform count (FCC), Escherichia coli count, percentage of E. coli, and Staphylococcus aureus, percentage of fat, protein, lactose, total solid and solid non-fat. Increasing THI was associated with a significant decrease in all milk main components. An increase of TCC, FCC, and E. coli count from mxTHI<72 to mxTHI>78 was observed. In addition, the isolation rate of both S. aureus and E. coli increased when the mxTHI increased. The results of this study show the seriousness of the negative effects of hot conditions on milk composition and mammary gland pathogens. These facts warrant the importance of adopting mitigation strategies to alleviate negative consequences of heat stress in dairy cows and for limiting related economic losses.

• Journal of Forest and Environmental Science
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• v.30 no.1
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• pp.120-125
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• 2014

Halophytes are plants of saline habitats that grow under conditions that may vary in extremes of temperatures (freezing to very hot), water availability (drought to water logging) and salinity (mild to almost saturation). Halophytes may also face sudden micro-environmental variations within their habitats. In this study, we examine some of the factors that determine the ability of seeds of Artemisia fukudo to germinate when conditions are optimal for seedling growth and survival. Germination percentage was the highest at 77.5% when treated in 0% seawater and seedling growth was best in 0% seawater plug cell tray. Physiological quality (chlorophyll contents) and mean germination time were best in the condition in which seeds were treated with 0% seawater (control). Germination performance index in the control group showed the highest value to 3.8. Seedling growth, seedling vigor index in the length of seedling growth andthe relative growth rate were the highest values of 0.76 cm, 1.43, 0.0099, respectively.