• Korean Management Science Review
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• v.27 no.2
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• pp.1-20
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• 2010

Many firms are trying to acquire innovative technologies and relative knowledge by offshoring R&D work. Although research to date has focused on the multinational corporations' motivations of R&D offshoring, such as cost reduction and market expansion, little is known about external or environmental factors influencing the performance of global R&D activities. We investigated the relationship between the offshore R&D performance and the technical capabilities of the parent company, the host country and the home country as enhancers from outside R&D facilities. The analysis uses European patent data and EU R&D scoreboard of 134 overseas R&D labs from 46 multinational corporations in 2005. Also, we calculated total patent number of each country for this. Results from path analysis supported our main hypothesis that the technological capabilities of the parent company and the host country positively affect the overseas R&D performances. By multi-group analysis, we also found that the relationships among the variables are different for each industry.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.7C
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• pp.743-750
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• 2003

With the expansion of computer technology the mobility of a mobile agent code having the flexibility in the dispersive computer situation is used to set up the applications distributed on the Internet. As it also has the ability to transmit the mobile code of a mobile agent and to receive it from a far-off host, the executive circumstances of the host system in which an agent is executed have to access to an agent code and the executive state capable of executing an agent code. Therefore, it is difficult to prevent the forgery, the alteration and the wrong execution of an agent from a malicious host. This dissertation suggests the mechanism which can protect an agent from the malicious action through the executive pursuit of a code-named mobile agent. The security of this mechanism is verified through the protective process of a mobile agent in this mechanism.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.85.4-85.4
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• 2019

Supernovae (SNe) are well known as good cosmological distance probes owing to their brightness and well-characterized light curve property. Specifically, type Ia SNe have contributed greatly to our understanding of acceleration of cosmic expansion. However, type IIP supernovae occur most frequently (~ 40% of all) at low and high redshift. As knowledge on the type IIP SNe increases, distance measurement methods using type IIP SNe have evolved. In this study, we apply Photometric Color Method (PCM), which needs only photometric data using properties of plateau on type IIP SNe light curves, to measure distances of several host galaxies of SNe IIP from the Intensive Monitoring Survey of Nearby Galaxies (IMSNG). The daily monitoring of galaxies at < 50 Mpc allows us to construct a dense light curve of SNe that occurred in our target galaxies. We observed two SNe IIP, SN2014cx and SN2017eaw and measured distances to their host galaxies, NGC 337 and NGC6946 respectively. Our results are comparable with other secondary distance measurement methods, 4-5 Mpc, however smaller than the result derived from the Tip of Red Giant Branch (TRGB) method, $6.7{\pm}0.2$ and $7.7{\pm}0.3Mpc$.

• Mycobiology
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• v.50 no.3
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• pp.166-171
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• 2022

Virginia creeper (or five-leaved ivy; Parthenocissus quinquefolia) is one of the most popular and widely grown climbers worldwide. In September 2021, Virginia creeper leaves with typical rust symptom were found in an arboretum in Korea, with severe damage. Globally, there is no record of a rust disease on Virginia creeper. Using morphological investigation and molecular phylogenetic inferences, the rust agent was identified as Neophysopella vitis, which is a rust pathogen of other Parthenocissus spp. including Boston ivy (P. tricuspidata). Given that the two ivy plants, Virginia creeper and Boston ivy, have common habitats, especially on buildings and walls, throughout Korea, and that N. vitis is a ubiquitous rust species affecting Boston ivy in Korea, it is speculated that the host range of N. vitis may recently have expanded from Boston ivy to Virginia creeper. The present study reports a globally new rust disease on Virginia creeper, which could be a major threat to the ornamental creeper.

• Journal of the Optical Society of Korea
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• v.1 no.2
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• pp.67-73
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• 1997

Light wave diffraction from multiple superposed volume gratings is inestigated using a perturbative iteration method of the integral equation of Maxwell's wave equation. The host material and index gratings are anisotropic and non-coplanar multiple volume gratings are considered. In this method, the paraxial approximation and lack of backward scattering in conventional coupled mode theory are not assumed. Systematic analysis of anisotropic wave diffraction due to multiple noncoplanar volume index gratings is performed in increasing level of diffraction orders corresponding to successive iterations.

• Journal of Sericultural and Entomological Science
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• v.38 no.1
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• pp.42-47
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• 1996

To investigate the host range determining factors of nuclear polyhedrois virus (NPV), Autographa california NPV and Bombyx mori NPV were coinfected into the two different cell lines, BmN-4 and Sf-9. The recombinant baculoviruses, RecS-A6 and RecB-727 which have an expanded host range, were isolated from Sf-9 and BmN-4 cell lines, respectively. The molecular biological characteristics of the recombinant baculoviruses were investigated. The pathogenicity of RecB-727 was similar to that of wild type BmNPV, while the pathogenicity of RecS-A6 was relatively lower than that of wild type BmNPV. The restriction enzyme digestion patterns of parental viruses and recombinant viruses showed that the recombinant virus has an expanded host range by genetic recombination. Southern blot analysis revealed that the p10 gene of RecB-727 was derived from AcNPV genomic DNA, while RecS-A6 has p10 gene of BmNPV in a viral genome. To investigate the host range expansion mechanism of recombinant baculovirus, HindIII-SacI 0.6 kb DNA fragments of RecS-A6 and RecB-727 were cloned and sequenced. The results showed that of wild type BmNPV helicase gene, suggesting that the expanded host range of recombinant baculoviruses was due to the insertion of BmNPV helicase gene into AcNPV viral genome.

• 한국정보디스플레이학회:학술대회논문집
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• 2004.08a
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• pp.220-222
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• 2004

Feasibility of BaO-ZnO-$B_2O_3$ (BZB) based glass system in the light of dielectric and thermal expansion properties are reported in the literature. Effects of addition of various types of ceramic fillers to the BZB-based glass on the thermochemical stability and mechanical properties were investigated in the present work. The studied filler-glass system demonstrated a capability to host various types of ceramic fillers to form thermochemically stable microcomposites at the processing temperature suitable for PDP systems. At the same time, mechanical strength of the filler-glass composites was much improved as compared to the glass itself These observations brighten the feasibility of the Pb-free BZB-based glass system as a host to employ various types of crystalline ceramic fillers so that it can be applied to barrier rib material in plasma display panels.

• Molecules and Cells
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• v.38 no.11
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• pp.966-974
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• 2015

Despite the presence of toll like receptor (TLR) expression in conventional $TCR{\alpha}{\beta}$ T cells, the direct role of TLR signaling via myeloid differentiation factor 88 (MyD88) within T lymphocytes on graft-versus-host disease (GVHD) and graft-versus-leukemia (GVL) effect after allogeneic stem cell transplantation (allo-SCT) remains unknown. In the allo-SCT model of C57BL/6 ($H-2^b$) ${\rightarrow}$ B6D2F1 ($H-2^{b/d}$), recipients received transplants of wild type (WT) T-cell-depleted (TCD) bone marrow (BM) and splenic T cells from either WT or MyD88 deficient (MyD88KO) donors. Host-type ($H-2^d$) P815 mastocytoma or L1210 leukemia cells were injected either subcutaneously or intravenously to generate a GVHD/GVL model. Allogeneic recipients of MyD88KO T cells demonstrated a greater tumor growth without attenuation of GVHD severity. Moreover, GVHD-induced GVL effect, caused by increasing the conditioning intensity was also not observed in the recipients of MyD88KO T cells. In vitro, the absence of MyD88 in T cells resulted in defective cytolytic activity to tumor targets with reduced ability to produce IFN-${\gamma}$ or granzyme B, which are known to critical for the GVL effect. However, donor T cell expansion with effector and memory T-cell differentiation were more enhanced in GVHD hosts of MyD88KO T cells. Recipients of MyD88KO T cells experienced greater expansion of Foxp3- and IL4-expressing T cells with reduced INF-${\gamma}$ producing T cells in the spleen and tumor-draining lymph nodes early after transplantation. Taken together, these results highlight a differential role for MyD88 deficiency on donor T-cells, with decreased GVL effect without attenuation of the GVHD severity after experimental allo-SCT.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.45.1-45.1
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• 2013

Type Ia supernovae (SNe Ia) are a powerful tool to investigate the expansion history of the universe, because their peak luminosity is as bright as a galaxy and is known as an excellent standard candle. Since the discovery of the acceleration of the universe based on the observations of SNe Ia, higher than ever accuracy of their peak luminosity is needed to investigate various problems in cosmology. We started a project to improve the accuracy of the calibration of the peak luminosity of SNe Ia by measuring accurate distances to nearby resolved galaxies that host SNe Ia. We derive accurate distances to the SN Ia host galaxies using the method to measure the luminosity of the tip of the red giant branch (TRGB). In this study we present the results for M66 and M96 in the Leo I Group which are nearby spiral galaxies hosting SN 1989B and SN 1998bu, respectively. We obtain VI photometry of resolved stars in these galaxies from F555W and F814W images in the Hubble Space Telescope archive. We derive the distances to these galaxies from the luminosity of the TRGB. With these results we derive absolute maximum magnitudes of two SNe (SN 1989B in M66 and SN 1998bu in M96). We derive a value of the Hubble constant from the optical magnitudes of these SNe Ia and SN 2011fe in M101 based on our TRGB analysis. This value is similar to the values derived from recent estimates from WMAP9 and Planck results, but smaller than other recent determinations based on Cepheid calibration for SNe Ia luminosity.

• IMMUNE NETWORK
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• v.15 no.3
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• pp.125-134
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• 2015

Acute graft-versus-host-disease (GVHD) is characterized by selective damage to the liver, the skin, and the gastrointestinal tract. Following allogeneic hematopoietic stem cell transplantation, donor bone marrow (BM) cells repopulate the immune system of the recipient. We previously demonstrated that the acute intestinal GVHD (iGVHD) mortality rate was higher in MyD88-deficient BM recipients than that in the control BM recipients. In the present study, the role of MyD88 (expressed by donor BM) in the pathophysiology of hepatic GVHD (hGVHD) was examined. Unlike iGVHD, transplantation with MyD88-deficient T-cell depleted (TCD) BM attenuated hGVHD severity and was associated with low infiltration of T cells into the liver of the recipients. Moreover, GVHD hosts, transplanted with MyD88-deficient TCD BM, exhibited markedly reduced expansion of $CD11b^+Gr-1^+$ myeloidderived suppressor cells (MDSC) in the liver. Adoptive injection of the MDSC from wild type mice, but not MyD88-deficient mice, enhanced hepatic T cell infiltration in the MyD88-deficient TCD BM recipients. Pre-treatment of BM donors with LPS increased MDSC levels in the liver of allogeneic wild type BM recipients. In conclusion, hGVHD and iGVHD may occur through various mechanisms based on the presence of MyD88 in the non-T cell compartment of the allograft.