• International Journal of Industrial Entomology and Biomaterials
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• v.12 no.1
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• pp.45-49
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• 2006

The present investigation was conducted to know the effects of host age on development and morphological characteristics of Nesolynx thymus, a gregarious ectopupal parasitoid of the uzi fly, Exorista bombycis, a serious en do-larval parasitoid of the silkworm, Bombyx mori L. For experimentation, 3 - 11 day-old pupae of E. bombycis were exposed to 2 day-old adults of N. thymus at $25{\pm}2^{\circ}C\;and\;60{\pm}10%$ RH. A highly significant negative correlation between host age and the following development and morphological characteristics of the parasitoid was observed: number of pupae parasitised, total adult recovery, sex ratio and recovery, longevity, body length, wing span, abdomen length, and abdomen width of females. The findings of the present study clearly demonstrate that various development and morphological parameters of N. thymus are influenced by the age of E. bombycis pupae.

• Publications of The Korean Astronomical Society
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• v.30 no.2
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• pp.487-488
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• 2015

In type Ia supernovae (SNe Ia) cosmology, a well-established correlation exists between the mass of host galaxies and the Hubble residual (HR) of SNe Ia. In order to investigate the origin of this correlation, we used low-resolution spectroscopic data of early-type host galaxies obtained from our YOnsei Nearby Supernovae Evolution Investigation (YONSEI) project. We measured velocity dispersions and Lick/IDS absorption line indices from these fully calibrated spectra. These indices were used to estimate the luminosity-weighted mean age, metallicity and mass of host galaxies. We found a tight correlation between host mass and population age, which is consistent with the "downsizing" trend in early-type galaxies. This suggests that the well-established correlation between HR and host mass is most likely due to the difference in population age. More observations, which are in progress, are required to understand the impact of luminosity evolution on SNe Ia cosmology.

• The Bulletin of The Korean Astronomical Society
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• v.42 no.1
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• pp.53.2-53.2
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• 2017

The origin of the well-known correlation between Hubble residual of Type Ia Supernova (SN Ia) and mass of their host galaxies is yet to be fully understood. In our first paper of our YOnsei Evolutionary Supernovae Evolutionary Investigation (YONSEI) project, we found a significant (${\sim}3.9{\sigma}$) correlation between host galaxy mass (velocity dispersion) and population age from high S/N host spectra observed using LCO 2.5 m telescope. Since there is no correlation with metallicity, our result suggests that stellar population age is mainly responsible for the relation between host mass and HR. In order to explore this more directly, we have subsequently observed more sample of nearby early-type host galaxies using MMT 6.5 m telescope. In this poster presentation, we will report our progress in this project and show the preliminary results from our MMT observations.

• The Bulletin of The Korean Astronomical Society
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• v.39 no.1
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• pp.36.1-36.1
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• 2014

The correlation between mass of Type Ia Supernova (SN Ia) host galaxies and Hubble residual is now well-established. The origin of this relation, however, is yet to be understood. We have used low-resolution spectra of early-type hosts from YONSEI (YOnsei Nearby Supernovae Evolution Investigation) project to measure central velocity dispersion and Lick/IDS absorption indices. By using the Evolutionary Population Synthesis (EPS) models, luminosity-weighted mean age and metallicity of host galaxies were determined from $H{\beta}$ and absorption lines. Here we will discuss the correlation between the velocity dispersion, which indicates the mass of galaxies, and mean age of stellar population in our sample of early-type host galaxies.

• Korean Journal of Veterinary Research
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• v.47 no.1
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• pp.77-84
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• 2007

Helicobacter pylori (H. pylori) is an important bacterial pathogen that causes chronic gastritisand is associated with gastroduodenal ulcer disease, adenocarcinoma of the distal stomach, and gastricH. pylori infection associated with host agehave not been well-defined in human. To evaluate the difference in host susceptibility to infection in relationto age of acquisition of H. pylori infection, we designed an experiment involving inoculation of H. pyloriATC 43504 at different ages of Mongolian gerbils. H. pylori was inoculated at 5 weeks and 18 monthsof age, as representatives of early and late infection, respectively. Animals were sacrificed 1 week and 4weeks after challenge, and the stomach was removed from each animal for bacterial culture, histologicalexamination, and polymerase chain reaction test. 5 week-old gerbils revealed infection andmaintained continuously its infection until 4 weeks. However, old gerbils did not maintained H. pyloriinfection. These data suggest the insusceptibility of H. pylori in old Mongolian gerbils and the importanceof animal ages for successful animal experimental infection. Also, the results demonstrated that earlyinfection of H. pylori increases its host susceptibility, as compared to the case with later infection, possiblybecause of differences in host gastric mucosal factors and imunologic responses.

• Korean journal of applied entomology
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• v.48 no.1
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• pp.21-27
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• 2009

Paromius exiguus (Distant) has caused serious damage by pecky grains around Gimpo paddy fields in 2001. We conducted field and laboratory studies to determine the seasonal occurrence and age distribution of P. exiguus on the three major host plants. The overwintering P. exiguus was found mainly on the basal part of gramineae weeds in various localities. After overwintering, in mid-May, the adults aggregated on the grain parts of Imperata cylindrica, laid their eggs and nymphs developed into adults on the same host plants. By the time, the Calamagrostis epigeios colony had newly occupied I. cylindrica areas, the nymphs and adults of first generation had already moved to the second host. The second generation of P. exiguus, after having completed its life cycle on C. epigeios, the newly emerged adults migrated to the rice plants and other gramineae weeds in early August. Afterwards, they complete its third generation cycle where they can move to the overwintering site again. P. exiguus has the five nymphal stages and each nymphal stage could be determined by head or prothoracic width. On the I. cylindrica and O. sativa hosts, the age distribution of P. exiguus showed a simple structure as each stage ratio increased stepwise with time. But in case of C. epigeios, as the newly emerged adults and immature nymphs continuously migrate after a month from the I. cylindrica, the age structure became remarkably complex. The peak nymphal density was observed when the ratio of third and forth instar was the highest in the population. The finding about the specific age structure on each generation of the insect would be very useful in control decision making on the major host plants. It is also important to consider the host's specificity to pesticide sensitivity in relation to various nymphal stages.

• International Journal of Industrial Entomology and Biomaterials
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• v.29 no.1
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• pp.128-134
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• 2014

Nesolynx thymus Girault (Hymenoptera: Eulophidae) is one among 20 hymenopteran parasitoids reported to attack the uzi fly, Exorista bombycis, which in turn infests the silkworm, Bombyx mori accounting a cocoon yield loss of 10-20%. A host of factors viz., age and size of host, age and size of parasitoid, availability of host, temperature and quality of host are reported to influence the reproductive efficiency of the parasitoids. In the present study an attempt was made to record the influence of foraging parasitoid density on their reproductive performance. Three day-old uzi pupae were offered to varying numbers (1 - 10) of 2 day old Nesolynx thymus adults for parasitization. The progeny production per pupa (84.44 - 132.77) increased significantly with increase in the number of foraging parasitoid adults (1 - 10) however, progeny production per female decreased. The sex ratio (M : F) (1:25.49 - 1:1.53) decreased significantly with increase in foraging parasitoid adults. The morphometric parameters except female abdomen width of first generation parasitoid showed significant negative correlation with number of foraging adults. However, correlation between the parasitoid size in first generation and their reproductive performance was nonsignificant.

• Animal cells and systems
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• v.1 no.3
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• pp.491-496
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• 1997

When olfactory placodes are transplanted at stages 23/24 from Xenopus laevis to Xenopus borealis hosts of the same age, it is possible to distinguish the cell populations of the host and donor due to the peculiar nuclear Q bands specific to X. borealis. I have replaced the eye anlage in each of a number of X. borealis with the transplanted olfactory placode of an individual X. laevis, or vice versa. In most instances, the placode of the donor fuses with that of the host. When fusion occurs, but not when the host and donor orqans grow separately, the cells of the donor were replaced gradually and according to a characteristic pattern by cells of the host. The basal cells of the donor were the first to be replaced, followed by the more matured cells of the sensory epithelium. This cellular substitution, proceeding in an orderly fashion from bottom to upper layers of the epithelium, depends on the fusion of the two organs. This observation suggests intercellular contacts in the mitotic zone of the two organs favor the host's cells over those of the donor.

• The Bulletin of The Korean Astronomical Society
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• v.38 no.2
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• pp.56.1-56.1
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• 2013

Supernovae type Ia (SNe Ia) cosmology is providing the only direct evidence for the presence of dark energy. This result is based on the assumption that the look-back time evolution of SNe Ia luminosity, after light-curve shape correction, would be negligible. However, the most recent compilation of SNe Ia data shows systematic difference in the Hubble residual (HR) between the E and Sd/Irr galaxies, indicating that the light-curve fitters used by the SNe Ia community cannot quite correct for a large portion of the population age effect. In order to investigate this possibility more directly, we have obtained low-resolution spectra for 30 nearby early-type host galaxies. This data set is used to estimate the luminosity-weighted mean ages and metallicities of host galaxies by employing the population synthesis models. We found an interesting trend between the host galaxy age and HR, in the sense that younger galaxies have positive residuals (i.e., light-curve corrected SNe Ia luminosity is fainter). This result is rather independent of the choice of the population synthesis models employed. Taken at face value, this age (evolution) effect can mimic a large fraction of the HR used in the discovery of the dark energy. This result is significant at 1.4 - 3 sigma levels, depending on the light curve fitters adopted, and further observations and analyses are certainly required to confirm the trend reported here.

• IMMUNE NETWORK
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• v.21 no.1
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• pp.3.1-3.16
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• 2021

Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been spreading worldwide since its outbreak in December 2019, and World Health Organization declared it as a pandemic on March 11, 2020. SARS-CoV-2 is highly contagious and is transmitted through airway epithelial cells as the first gateway. SARS-CoV-2 is detected by nasopharyngeal or oropharyngeal swab samples, and the viral load is significantly high in the upper respiratory tract. The host cellular receptors in airway epithelial cells, including angiotensin-converting enzyme 2 and transmembrane serine protease 2, have been identified by single-cell RNA sequencing or immunostaining. The expression levels of these molecules vary by type, function, and location of airway epithelial cells, such as ciliated cells, secretory cells, olfactory epithelial cells, and alveolar epithelial cells, as well as differ from host to host depending on age, sex, or comorbid diseases. Infected airway epithelial cells by SARS-CoV-2 in ex vivo experiments produce chemokines and cytokines to recruit inflammatory cells to target organs. Same as other viral infections, IFN signaling is a critical pathway for host defense. Various studies are underway to confirm the pathophysiological mechanisms of SARS-CoV-2 infection. Herein, we review cellular entry, host-viral interactions, immune responses to SARS-CoV-2 in airway epithelial cells. We also discuss therapeutic options related to epithelial immune reactions to SARS-CoV-2.