• Title/Summary/Keyword: Hospital unit

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Pk/PD Study Using PET Biomarker

  • Yu, Kyung-Sang;Jang, In-Jin;Lim, Kyoung-Soo;Kwon, Jun-Soo;Jeong, Jae-Min;Lee, Jae-Sung;Kim, Jung-Ryul;Cho, Joo-Youn;Shin, Sang-Goo
    • 대한임상약리학회:학술대회논문집
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    • 2006.11a
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    • pp.141-142
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    • 2006

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Potential clinical utility of intraoperative fluid amylase measurement during pancreaticoduodenectomy

  • Kunal Joshi;Manuel Abradelo;David Christopher Bartlett;Nikolaos Chatzizacharias;Bobby Venkata Dasari;John Isaac;Ravi Marudanayagam;Darius Mirza;Keith Roberts;Robert Peter Sutcliffe
    • Annals of Hepato-Biliary-Pancreatic Surgery
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    • v.27 no.2
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    • pp.189-194
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    • 2023

  • Backgrounds/Aims: Postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy (PD) is a source of major morbidity and mortality. Early diagnosis and treatment of POPF is mandatory to improve patient outcomes and clinical risk scores may be ombined with postoperative drain fluid amylase (DFA) values to stratify patients. The aim of this pilot study was to etermine if intraoperative fluid amylase (IFA) values correlate with DFA1 and POPF. Methods: In patients undergoing PD from February to November 2020, intraoperative samples of intra-abdominal fluid adjacent to the pancreatic anastomosis were taken and sent for fluid amylase measurement prior to abdominal closure. Data regarding patient demographics, postoperative DFA values, complications, and mortality were prospectively collected. Results: Data were obtained for 52 patients with a median alternative Fistula Risk Score (aFRS) of 9.9. Postoperative complications occurred in 20 (38.5%) patients (five Clavien grade ≥ 3). There were eight POPFs and two patients died (pneumonia/sepsis). There was a significant correlation between IFA and DFA1 (R2 = 0.713; p < 0.001) and DFA3 (p < 0.001), and the median IFA was higher in patients with POPF than patients without (1,232.5 vs. 122; p = 0.0003). IFA > 260 U/L predicted POPF with sensitivity, specificity, positive and negative predictive values of 88.0%, 75.0%, 39.0%, and 97.0%, respectively. The incidence of POPF was 43.0% in high-risk (high aFRS/IFA) and 0% in lowrisk patients (low aFRS/IFA). Conclusions: IFA correlated with POPF and may be a useful adjunct to clinical risk scores to stratify patients during PD. Larger, prospective studies are needed to determine whether IFA has clinical utility.

  • https://doi.org/10.14701/ahbps.22-083 인용 PDF

A Case Study on Hospital Unit Management System (책임경영제 운영사례)

  • Hwang, In-Kyoung
    • Korea Journal of Hospital Management
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    • v.7 no.2
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    • pp.124-135
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    • 2002

  • The purpose of this study is to analyze a case of unit management system introduced and operated in a university hospital. The system was designed and applied to six clinical departments and centers to help to achieve the medical revenue and profit targets. The case hospital is now in the second year of the system operation. Major findings of the study are as follows; Firstly, the leadership style of the unit manager is the most important factor in management of the unit. The transformational leadership style was more effective than the transactional one. Secondly, unit manager's managerial ability is another key factor to the success or failure in achieving the responsibility targets. Thirdly, the degree of divisionalization and responsibility should be strengthened to activate both unit managers and medical specialists.

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