• Architectural research
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• v.22 no.4
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• pp.113-122
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• 2020

Hospital architecture must be planned as a therapeutic space. Numerous studies have proven that exposure to nature has a healing effect. However, research on the architecture itself about this issue is still insufficient. This study analyzed Le Corbusier's Venice hospital project and its architectural configurations with nature. Le Corbusier had been interested in blurring the interior/exterior line to draw nature inside. In his projects, nature was conceived in an abstract sense as "something green." However, in the hospital project, natural elements including vegetation, the lagoon, and light, and the landscape scenery they created, were considered in the harmony of the architectural space. The architectural spaces with courtyards, pilotis, and roof gardens provided views and direct access to nature, and in the interior spaces, the connections to these external spaces and the permeation of views of nature and sunlight were incorporated. Many spaces provided the possibility to actually encounter nature, with a variety of indoor/outdoor space configurations rather than a merely passive placing of some natural elements. This project is considered to be an important reference for contemporary hospital architecture, since the architectural space and nature connected through various spatial configurations also in healthcare programs. As Le Corbusier emphasized, sunlight, vegetation, and also architectural space should be an essential factor in therapeutic hospital architecture planning.

• Korea Journal of Hospital Management
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• v.1 no.1
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• pp.136-153
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• 1996

The purpose of this study is to identify the factors hindering hospital reengineering project in one university hospital. The data was collected by the self-administered Questionnaire to 288 members of the hospital in Pusan on April 5-18, 1996. This study took some statistical methodologies, such as descriptive analysis, factor analysis and logit model analysis. The results were as follows; First, in the descriptive analysis for whether the hospital reengineering named RUSH94 was a success or not, the subjects judged that it was not successful and regarded their fable mutual communication as the main factor. Second, in the reason of failure at the reengineering project, the group who thought that the failure factor was the lack of mutual consensus checked the scores of the first factor produced from the factor analysis.

• Journal of Preventive Medicine and Public Health
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• v.55 no.4
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• pp.351-359
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• 2022

Objectives: The Regional CardioCerebroVascular Center (RCCVC) project was initiated to improve clinical outcomes for patients with acute myocardial infarction or stroke in non-capital areas of Korea. The purpose of this study was to evaluate the outcomes and issues identified by the Busan RCCVC project in the treatment of ST-segment elevation myocardial infarction (STEMI). Methods: Among the patients who were registered in the Korean Registry of Acute Myocardial Infarction for the RCCVC project between 2007 and 2019, those who underwent percutaneous coronary intervention (PCI) for STEMI at the Busan RCCVC were selected, and their medical data were compared with a historical cohort. Results: In total, 1161 patients were selected for the analysis. Ten years after the implementation of the Busan RCCVC project, the median door-to-balloon time was reduced from 86 (interquartile range [IQR], 64-116) to 54 (IQR, 44-61) minutes, and the median symptom-to-balloon time was reduced from 256 (IQR, 180-407) to 189 (IQR, 118-305) minutes (p<0.001). Inversely, the false-positive PCI team activation rate increased from 0.6% to 21.4% (p<0.001). However, the 1-year cardiovascular death and major adverse cardiac event rates did not change. Even after 10 years, approximately 75% of the patients had a symptom-to-balloon time over 120 minutes, and approximately 50% of the patients underwent inter-hospital transfer for primary PCI. Conclusions: A decade after the implementation of the Busan RCCVC project, although time parameters for early reperfusion therapy for STEMI improved, at the cost of an increased false-positive PCI team activation rate, survival outcomes were unchanged.

• Tuberculosis and Respiratory Diseases
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• v.70 no.2
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• pp.143-149
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• 2011

Background: Stopping medical treatment by tuberculosis (TB) patients prior to completing treatment period is a major concern in private hospitals. We evaluated the impact of public-private mix (PPM) project on increasing treatment success rate of TB in a private tertiary hospital in Korea. Methods: Starting in February 2009, TB patients treated at Dankook University Hospital received health education and case monitoring activities by specially trained public health nurses (PPM project). On a retrospective basis, we reviewed medical records and compared the treatment outcome of TB patients treated under the PPM project (PPM group) to patients treated without the PPM project (control group) between January 2008 and June 2010. In addition, we also evaluated the risk factors treatment non-completion. Results: The number of patients in the PPM group and control group were 123 (85 pulmonary TB and 38 extrapulmonary TB) and 146 (101 pulmonary TB and 45 extra-pulmonary TB), respectively. The PPM group had demographic and clinical findings comparable to those of control group. The PPM group showed a significantly higher treatment success rate (93.5%) compared to the control group (77.9%). However, development of complications, proximity to the hospital, and presence of co-morbid disease did not influence the treatment success rate. Conclusion: The PPM project was effective at increasing the TB treatment success rate. An effort to improve and to expand the PPM project is needed in private Korean hospitals.

• Korean Journal of Construction Engineering and Management
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• v.5 no.3 s.19
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• pp.153-165
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• 2004

Most engineering tasks require collaboration between many users in major hospital construction projects that have many reconstructions. Loss and change orders occurred in factors such as information exchange, misunderstandings, advanced technology in hospital projects. Moreover, changes in context, costs, requirements, deadlines, etc. require negotiation of issues that may modify important project characteristics. The objective of this paper is to reduce reconstruction for the pre-construction process of hospital projects, reconstruction factors were analyzed in recent hospital construction project the system was established in order to solve reconstruction factors, and this system was validated through applying to the real project. Therefore it is a major challenge to make high level of communication and to have mutual understanding.

• Journal of The Korea Institute of Healthcare Architecture
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• v.21 no.3
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• pp.47-55
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• 2015

Purpose: While medical standard is rapidly improved, welfare of users and employees in hospitals is not treated correspondingly. Intercommunication of hospital users is thought to be very important for their welfare, and provision of conversation spaces within hospital environment needs to be expanded by architectural design. Space organization methods for the design of conversation space is to be embellished. Methods: Literature and hospital designs are analysed in order to develop the basis of argumentation for the hospital conversation space. 15 hospitals are reviewed and designed spaces for the intercommunication of the users are examined, Space organization efforts and design experiments are identified, and 6 organizational methods are proposed such as: 1) reducing territoriality 2) flowing space 3) categorizing and separating spaces 4) height variation 5) contact with outside and 6) Sun-lighted space. Results: 6 organization methods are confirmed in precedent hospital cases, and these proposed methods are applied in a new hospital design project to verify their usefulness. Implications: A hospital design project is presented based on these proposed methods of organization for the conversation space. Outcomes of this study can be applied for the formulation of human intercommunication spaces in other facilities.

• Korea Journal of Hospital Management
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• v.19 no.2
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• pp.106-114
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• 2014

• IMMUNE NETWORK
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• v.24 no.2
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• pp.7.1-7.19
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• 2024

Viral load and the duration of viral shedding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are important determinants of the transmission of coronavirus disease 2019. In this study, we examined the effects of viral doses on the lung and spleen of K18-hACE2 transgenic mice by temporal histological and transcriptional analyses. Approximately, 1×10⁵ plaque-forming units (PFU) of SARS-CoV-2 induced strong host responses in the lungs from 2 days post inoculation (dpi) which did not recover until the mice died, whereas responses to the virus were obvious at 5 days, recovering to the basal state by 14 dpi at 1×10² PFU. Further, flow cytometry showed that number of CD8+ T cells continuously increased in 1×10² PFU-virus-infected lungs from 2 dpi, but not in 1×10⁵ PFU-virus-infected lungs. In spleens, responses to the virus were prominent from 2 dpi, and number of B cells was significantly decreased at 1×10⁵ PFU; however, 1×1² PFU of virus induced very weak responses from 2 dpi which recovered by 10 dpi. Although the defense responses returned to normal and the mice survived, lung histology showed evidence of fibrosis, suggesting sequelae of SARS-CoV-2 infection. Our findings indicate that specific effectors of the immune response in the lung and spleen were either increased or depleted in response to doses of SARS-CoV-2. This study demonstrated that the response of local and systemic immune effectors to a viral infection varies with viral dose, which either exacerbates the severity of the infection or accelerates its elimination.

• Journal of Korean Neurosurgical Society
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• v.60 no.3
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• pp.322-326
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• 2017

Neuroendoscopic surgery is performed because it causes minimal damage to normal structures, carries a lower rate of complications, and achieves excellent outcomes. Surgeons using an endoscope and related instruments can perform complex operations through very small incisions, which is especially useful for minimally invasive procedures for the brain and spine. Neuroendoscopic surgery is now performed in cases of obstructive hydrocephalus, various intraventricular lesions, hypothalamic hamartomas, craniosynostosis, skull base tumors, and spinal lesions. This review discusses the brief history of neuroendoscopy and the current state and future perspectives of endoscopic surgery.

• Proceedings of the PSK Conference
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• 2005.11a
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• pp.123-124
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• 2005