• Journal of The Korea Institute of Healthcare Architecture
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• v.22 no.4
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• pp.47-55
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• 2016

Purpose: Growth and change are the most important things in planning of hospital architecture. It is especially necessary for countless changes taken place since the hospital opens to be adapted to the planning of hospital architecture phase. The space depth in the hospital serves a very crucial role in accepting these changes. The purpose of this study is to provide basic data necessary to space depth planning to prepare for change through analyzing space depth's change in hospital architecture chronologically. Methods:: The method of this study is analyzing space depth's change in cases of 19 hospitals in total, from the 1980's, which is the quantitative growth period, until recently. Especially this study is analyzing Max & Min space depth focusing change of medical environment. Based on this, this study suggests an form of space depth and optimum range of space depth response to growth and change of hospital architecture. Results: The conclusions of this study are as follows. Considering these conclusion, double linear system is most appropriate for space depth for hospital architecture planning focused on system. Optimal range of space depth is at least 21.6m or more in case of clinic room and from 27 meter to 37meter in case of examination & treatment room. Implications: Space of Depth is a key element determining system for hospital architecture planning focused on system. The results of this paper can be data for planning system of hospital architecture which copes with the change.

• Journal of The Korea Institute of Healthcare Architecture
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• v.8 no.1
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• pp.21-28
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• 2002

As hospitals change continuously and rapidly, the way of growth and change becomes another important factor in the design of a hospital. The hospitals are adapted for the continuous growth and change during their life span. But the hospitals built in 1970's and 80's have been expanded and reconstructed without any plan of growth and change. So, there is required to the architectural planning on the remodeling and modernization strategy of general hospitals. The purpose of this study is to provide the fundamental data for the reasonable design planning and the basic principles of the construction plan in the hospital remodeling. Thus, this study is to investigate and analyze the characteristics of hospital remodeling, the remodeling planning, and the scheduling process in terms of construction. As a result, this study would apply to design guideline for the remodeling of general hospitals.

• Clinical and Experimental Pediatrics
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• v.61 no.7
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• pp.226-230
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• 2018

Purpose: This pilot study assessed changes in the growth plate and growth rates in children during a 6-month period. Methods: The study included 31 healthy children (17 boys, 14 girls) under evaluation for growth retardation. Height, weight, bone age, insulin like growth factor-1 (IGF-1), and insulin like growth factor binding protein 3 (IGF-BP3) were measured at baseline and after 6 months. In addition, the diameter, thickness, and volume of the femoral and tibial growth plates were measured using magnetic resonance imaging. Results: The mean bone age in boys and girls was 11.7 and 10.7 years, respectively. In boys, height (z score) (-0.2 vs. 0.0), weight (z score) (0.8 vs. 1.1), body mass index (BMI) (z score) (1.27 vs. 1.5), IGF-1 (ng/mL) (343.6 vs. 501.8), and IGF-BP3 (ng/mL) (5,088.5 vs. 5,620.0) were significantly higher after 6 months. In girls, height (z score) (-1.0 vs. -0.7), weight (z score) (-0.5 vs. 0.1), BMI (z score) (-0.02 vs. 0.3), IGF-1 (ng/mL) (329.3 vs. 524.6), and IGF-BP3 (ng/mL) (4,644.4 vs. 5,593.6) were also significantly higher after 6 months. In both sexes, the mean diameter and volume of the femoral and tibial growth plates were significantly increased 6 months later. Conclusion: No significant correlation was found between changes in the growth plate and clinical parameters in children with growth retardation in this study, other than correlations of change in femoral diameter with weight and BMI. A larger, long-term study is needed to precisely evaluate the correlation between change in the growth plate and growth.

• Asian Spine Journal
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• v.12 no.6
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• pp.1069-1077
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• 2018

Study Design: A case study. Purpose: To assess the chronological changes of the disease-related kyphosis after chemotherapy alone, secondly to clarify the role of growth cartilage in the healed lesion on kyphosis change, and to define the accurate prediction time in assessing residual kyphosis. Overview of Literature: None of the previous papers up to now dealt with the residual kyphosis, stability and remodeling processes of the affected segments. Methods: One hundred and one spinal tuberculosis children with various stages of disease processes, age 2 to 15 years, were the subject materials, between 1971 to 2010. They were treated with two different chemotherapy formula: before 1975, 18 months of triple chemotherapy (isoniazid [INH], para-aminosalicylic acid, streptomycin); and since 1976, 12 months triple chemotherapy (INH, rifampicin, ethambutol, or pyrazinamide). The first assessment at post-chemotherapy one year and at the final discharge time from the follow-up (36 months at minimum and 20 years at maximum) were analyzed by utilizing the images effect of the remaining growth plate cartilage on chronological changes of kyphosis after initiation of chemotherapy. Results: Complete disc destruction at the initial examination were observed in two (5.0%) out of 40 cervical spine, eight (26.7%) out of 30 dorsal spine, and six (19.4%) out of 31 lumbosacral spine. In all those cases residual kyphosis developed inevitably. In the remainders the discs were partially preserved or remained intact. Among 101 children kyphosis was maintained without change in 20 (19.8%), while kyphosis decreased in 14 children (13.7%), and increased in 67 children (66.3%) with non-recoverably damaged growth plate, respectively. Conclusions: It could tentatively be possible to predict the deformity progress or non-progress and spontaneous correction at the time of initial treatment, but it predictive accuracy was low. Therefore, assessment of the trend of kyphotic change is recommended at the end of chemotherapy. In children with progressive curve change, the deformity assessment should be continued till the maturity.

• Journal of Korean Neurosurgical Society
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• v.57 no.4
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• pp.276-282
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• 2015

Objective : The purpose of this study was to investigate morphological change at the craniovertebral junction (CVJ) region using computed tomography. Methods : A total of 238 patients were included in this study, and mean age was $47.8{\pm}21.3months$. Spinal canal diameter, Power's ratio, McRae line, antero-posterior C1 ring height, atlantoaxial joint space, C2 growth, epidural space from the dens (M-PB-C2) and longitudinal distance (basion to C2 lower margin, B-C2) were measured. The mean value of each parameter was assessed for individual age groups. The cohorts were then divided into three larger age groups : infancy (I) (${\leq}2years$), very early (VE) childhood (2-5 years) and early (E) childhood ($5{\geq}years$). Results : Spinal canal diameter increased with age; however, this value did not increase with statistical significance after VE age. A significant age-related difference was found for all C2 body and odontoid parameters (p<0.05). Mean McRae line was 8.5, 8, and 7.5 mm in the I, VE, and E groups, respectively. The M-PB-C2 line showed up-and-down dynamic change during early pediatric periods. Conclusion : Expansion of the spinal canal was restricted to the very early childhood period (less than 5 years) in the CVJ region; however, the C2 body and odontoid process increased continuously with age. The above results induced a dynamic change in the M-PB-C2 line. Although C2 longitudinal growth continued with age, the McRae line showed relatively little change.

• Journal of The Korea Institute of Healthcare Architecture
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• v.14 no.4
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• pp.21-30
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• 2008

Domestic hospital architectures were developed with the nation's industrialization after 1960s. Particularly, with the rapidly growing healthcare demands according to The National Health Insurance Plan which was introduced in 1977 and expanded to entire nation in 1989, the number of healthcare facility is also increasing according to the expansion of the existing facilities and construction of new buildings. Now, twenty to thirty years were past since that growing period of healthcare architecture. Many hospitals are facing on the phase of restructuring and modernization for their resources. J university hospital is a representative case of hospital development which the growth of facility was stopped by insufficient site area. This study, analysing its past statistics and drawing data of that hospital, presents the characteristics of the changes and basic data of the master planning for the future hospital development.

• Journal of The Korea Institute of Healthcare Architecture
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• v.16 no.2
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• pp.65-75
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• 2010

Space transformation of hospital architecture happens more rapidly than other types such as school and office buildings. This requirement is caused by medical demand, service transformation, technical development and equipment changes. Grand scale extension and rapid change in hospital architecture affects whole planning; therefore, it is important to design in the macro perspective such like Life Cycle. Grand scale extension is difficult process to rebuild growth and transfer of hospital architecture and to adapt to the future change. That's why simple planning gives limits to some departments in a short-term and brings another reform such as more extension or interior renovation in a long-term. This study surveys various space transformation and grand scale extension of EB hospital extended recently, and it is to find planning condition in extension.

• The Journal of Pediatrics of Korean Medicine
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• v.37 no.3
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• pp.121-132
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• 2023

Objectives We aimed to confirm whether Humulus japonicus Extract Powder can enhance child height growth significantly and safely compared with a placebo. Methods A total of 150 children between the 3rd and 25th percentiles in height and between the ages of 6 and 9 years will be recruited to participate in this randomized, double-blind, placebo-controlled clinical trial. The participants will be randomly assigned to the treatment or placebo group. Participants in the treatment group will take one pack per day (700 mg of Humulus japonicus Extract Powder) for 24 weeks. Participants in the placebo group will take one package of placebo per day (0 mg of Humulus japonicus Extract Powder) for 24 weeks. The primary outcome will be a change in height after 12 weeks, and the secondary outcomes will be the height after 24 weeks, growth rate, height standard deviation, growth hormone, insulin-like growth factor-1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), bone alkaline phosphatase (BALP), and osteocalcin after 12 and 24 weeks. Results This protocol was approved by the Institutional Review Board (IRB) of the Korean Medicine Hospital of Busan University (IRB No. PNUKHIRB-2023-03-002). Research participants will be recruited from June 2023 to December 2023. Conclusions The results of this study provide clinical information regarding the effectiveness and safety of the Humulus japonicus Extract Powder in increasing child height.

• Journal of Korean Neurosurgical Society
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• v.55 no.4
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• pp.205-207
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• 2014

Meningioma is a common primary tumor of central nervous system. However, extracranial extension of the intracranial meningioma is unusual, and mostly accompanied the osteolytic change of the skull. We herein describe an atypical meningioma having extracranial extension with hyperostotic change of the skull. The patient was a 72-year-old woman who presented a large mass in the right frontal scalp and left hemiparesis. Brain magnetic resonance imaging and computed tomography scans revealed an intracranial mass, diffuse meningeal thickening, hyperostotic change of the skull with focal extension into the right frontal scalp. She underwent total removal of extracranial tumor, bifrontal craniectomy, and partial removal of intracranial tumor followed by cranioplasty. Tumor pathology was confirmed as atypical meningioma, and she received adjuvant radiotherapy. In this report, we present and discuss a meningioma en plaque of atypical histopathology having an extracranial extension with diffuse intracranial growth and hyperostotic change of the skull.

• Journal of The Korea Institute of Healthcare Architecture
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• v.9 no.1
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• pp.53-60
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• 2003

In this study, I investigate the critical evaluation elements at the architectural competition held nationwide in Germany. These evaluation elements, which can be regarded as the important design evaluation criteria, are selected by the design competition committee. Generally, in Germany the design competition committee consist of professors and famous architects who have theoretical and practical abilities with their own office. I classify and analyze the critical evaluation elements of seventy committee members, working on the selected nine prize-winners in Germany from 1997 to 2001. I conclude that the critical evaluation elements, ordered by frequency are : (1)circulation, (2)context, (3)function, (4)landscape & outside space, (5)organization of space, (6)arrangement of building, (7)form, arrangement of building, (7)form, (7)growth & change, (9)elevation design, (10)utilization of natural light. These design evaluation growth & change, (9)elevation design, (10)utilization of natural light. These design evaluation criteria for Hospital Architecture in Germany also can be applied to the evaluation methods of the korean Healthcare facility design.