• The Journal of Pediatrics of Korean Medicine
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• v.24 no.1
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• pp.46-56
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• 2010

Objectives The purpose of this study is to report a Atopic dematitis patient treated by Horminis Placenta external wet therapy. Methods The patient was treated by acupuncture, herb medicine, especially Horminis Placenta external therapy. Kunz type, SCORAD index and Vas scale were used to measure the progression. Results and Conclusions We had evaluated the score during admission. SCORAD index include the extent, the intensity, pruritus, sleeping loss had increased from 52.88 score to 21.26 score. And the symptoms had improved with treatment.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.5
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• pp.1285-1289
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• 2006

Hominis placenta (HP) has been used as an agent for promoting physiological function in traditional asian medicine. The present study was peformed to investigate whether HP acupuncture treatment in an experimental tumor mice model inhibit tumor growth through immunomodulatory effects. Mice were inoculated subcutaneously with colon26-L5 cells on the back. Three days after tumor inoculation, HP herbal acupuncture treatment was conducted on BL18 acupoint every other day for three weeks. HP Herbal acupuncture treatment significantly suppressed the primary tumor growth and prolonged survival rate. To evaluate immunomodulatory effect of HP acupuncture, splenocytes proliferation assay, fluorescence-activated cell sorting (FACS) and ELISA for IFN- ${\gamma}$, and IL-4 cytokine level. HP herbal acupuncture enhanced the mitogenic activity of Balb/c whole splenocytes induced by various mitogenic stimuli and increased immune cell population such as T cell, B cell, Th cell, Tc cell and Macrophages. HP herbal acupuncture caused a marked increase of production of Th1 cytokine (IFN- ${\gamma}$ ,) and decrease of production of Th2 cytokine (IL-4). These results indicated that HP herbal acupuncture suppresses tumor growth through a mechanism leading to a Th1 dominant immune state.