• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제15권1호
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• pp.14-20
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• 2009

플래시 메모리는 현재 휴대용 기기 뿐 아니라 개인용 컴퓨터와 서버용 컴퓨터에서 널리 사용되고 있다 하드디스크를 위한 버퍼 캐시 교체 정책인 LRU(Least Recently Used)와 LFU(Least Frequently Used)는 플래시 메모리의 특성을 전혀 고려하지 않아 플래시 메모리에 적합하지 않다. 기존에 연구되었던 CFLRU(Clean-First LRU)와 그 변형인 CFLRU/C, CFLRU/E, DL-CPLRU/E는 플래시 메모리의 특성을 고려하였지만 hit ratio가 LRU와 LFU에 비하여 좋지 않다. 본 논문에서는 기존의 버퍼 캐시 교체 정책들을 보완하는 새로운 버퍼 캐시 교체 정책을 제안한다. 이 버퍼 캐시 교체 정책은 LFU를 기반으로 하고 플래시 메모리의 특성을 고려하였다. 그리고 이 새로운 버퍼 캐시 교체 정책을 기존 플래시 메모리 버퍼 캐시 교체 정책과 hit ratio와 flush 횟수를 비교하여 성능을 평가한다.

• 한국재료학회지
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• 제5권1호
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• pp.12-21
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• 1995

본 연구에서는 부식환경하에서 bulging 시험동안 음향방출거동에 미치는 변형률속도에 대한 영향을 알아보았다. 시험에 사용된 변형률속도의 범위는 $4 \times 10^{-6}S^{-1}$에서 $1 \times 10^{-4} \times S^{-1}$까지이며, AE신호 특성을 평가하기 위해 사용된 인자는 AE hit수와 진폭으로 하였다. 시험결과, 변형률속도가 감소함에 따라 등가파괴변형률과 원주방향의 균열 길이는 감소하였으나, 파괴과정동안 총 누적 AE hit수와 평균진폭은 크게 증가하였다. 그리고 AE신호 특성치의 최대점은 시험전분부에 접근하였으며, 단위 등가파괴변형률당 평균진폭이 20dB 이상에서는 뚜렷하게 응력부식륜열 현상을 관찰할 수 있었다. 또한 음향방출시험법은 변형률속도에 따른 재료의 응력부식균열 감수성 정도를 평가하는데 있어 그 적용 가능성이 있음을 알 수 있었다.

• The Korean Journal of Physiology and Pharmacology
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• 제8권1호
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• pp.51-55
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• 2004

Sopungsungi-won has been used as a traditional medicine for diabetes and it has been proved to be a potential remedy for type 2 diabetes mellitus. We previously reported that water extract of Sopungsungi-won exhibits anti-diabetic effects both in vivo and in vitro experiments. In the present study, we have chosen to examined anti-apoptotic effect of Rheum undulatum, which is the main component of Sopungsungi-won, on pancreatic ${\beta}-cells$, HIT-T15, against hydrogen peroxide $(H_2O_2)$. oxidative stress. To investigate the anti-apoptotic effect of Rheum undulatum water extract (RUWE) against $H_2O_2-induced$ apoptosis in pancreatic ${\beta}-cell$ line of hamster, HIT-T15, MTT assay, DAPI staining, TUNEL assay, RT-PCR and caspase-3 enzyme assay were performed. The morphological analysis demonstrated that cells treated with $H_2O_2$ exhibited classical apoptotic features, while such changes was reduced in cells pre-treated with RUWE. In addition, RUWE pre-treated cells prior to $H_2O_2$ treatment induced increase of levels of bcl-2 expression and decrease of caspase-3 enzyme activity compared to cells treated with $H_2O_2$ only. These results provide the possibility of usage of RU in patients with progressively deteriorated diabetes.

• Molecules and Cells
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• 제42권1호
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• pp.56-66
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• 2019

Histidine triad nucleotide-binding protein (HINT) is a member of the histidine triad (HIT) superfamily, which has hydrolase activity owing to a histidine triad motif. The HIT superfamily can be divided to five classes with functions in galactose metabolism, DNA repair, and tumor suppression. HINTs are highly conserved from archaea to humans and function as tumor suppressors, translation regulators, and neuropathy inhibitors. Although the structures of HINT proteins from various species have been reported, limited structural information is available for fungal species. Here, to elucidate the structural features and functional diversity of HINTs, we determined the crystal structure of HINT from the pathogenic fungus Candida albicans (CaHINT) in complex with zinc ions at a resolution of $2.5{\AA}$. Based on structural comparisons, the monomer of CaHINT overlaid best with HINT protein from the protozoal species Leishmania major. Additionally, structural comparisons with human HINT revealed an additional helix at the C-terminus of CaHINT. Interestingly, the extended C-terminal helix interacted with the N-terminal loop (${\alpha}1-{\beta}1$) and with the ${\alpha}3$ helix, which appeared to stabilize the dimerization of CaHINT. In the C-terminal region, structural and sequence comparisons showed strong relationships among 19 diverse species from archea to humans, suggesting early separation in the course of evolution. Further studies are required to address the functional significance of variations in the C-terminal region. This structural analysis of CaHINT provided important insights into the molecular aspects of evolution within the HIT superfamily.

• Composites Research
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• 제22권6호
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• pp.45-51
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• 2009

치아의 와동에 수복된 치과용 복합레진을 광(LED) 조사를 통해 경화 수축시키면서 음향방출(acoustic emission, AE)법을 이용하여 와동 벽면과 복합레진 사이의 계면상태를 실시간 해석하였다. 복합레진의 중합 수축에 의해 AE 신호들이 검출되었는데 계면 접착 상태가 나쁜 경우, 경화 수축률이 큰 초기 1분 동안 많은 AE 사상들이 관측되었으며, 이들 AE는 주파수범위가 주로 100-200kHz인 돌발형이었다. 인간치아 재질의 시편에서 발생된 AE 사상수는 스테인리스 스틸 시편보다 적었으나, PMMA 시편보다는 많았고 접착제의 도포 상태가 양호할수록 검출되는 AE 사상수는 적었다. AE 파라미터의 특성은 복합레진과 링재 사이의 접착부에서 발생하는 인장형 균열전파 및 복합레진의 수축에 따른 링재의 압축거동과 관련되었으며, 음향방출법이 치아 수복물의 접착성에 대한 비파괴 검사법으로써 유효함을 알았다.

• Journal of Acupuncture Research
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• 제41권2호
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• pp.115-120
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• 2024

Background: Migraine is a common disabling headache that affects every aspect of a person's life. Auricular acupuncture is a cost-effective treatment modality for the management of painful neurological conditions. Previous studies have shown the beneficial effects of a combination of ear points in the management of migraines. However, no studies have evaluated the efficacy of a single auricular point (i.e., sympathetic point) in migraine. Thus, this study evaluated the efficacy of sympathetic points on pain intensity and depression levels in patients with migraine. Methods: In this randomized controlled study, 100 patients with migraine aged 18-45 years were randomly divided into either an auricular acupuncture group (AAG) (n = 50) or a placebo control group (PCG) (n = 50). The AAG underwent needling at the sympathetic point (an auricular acupuncture point), whereas the PCG underwent needling at a non-acupuncture point for 20 minutes daily for 7 days. Assessments were performed before and after the intervention using a 6-item headache impact test (HIT-6) and Beck depression inventory (BDI) scale. Statistical analyses were performed using SPSS version 16. Results: In within-group analysis, the AAG showed a significant reduction in HIT-6 and BDI, whereas the PCG showed a significant increase in HIT-6 and a significant reduction in BDI. In between-groups analyses, HIT-6 reduced significantly in the AAG compared with that in the PCG, whereas BDI reduced significantly in the PCG compared with that in the AAG. Conclusion: In patients with migraine, needling at the sympathetic point produces a greater reduction in the pain intensity level and lesser reduction in the depression level compared to needling at a non-acupuncture point.

• 제어로봇시스템학회논문지
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• 제3권2호
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• pp.179-186
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• 1997

In this paper we suggest a development of surface defect inspection algorithms for cold mill strip. The defects which exist in a surface of cold mill strip have a scattering or singular distribution. This paper consists of preprocessing, feature extraction and defect classification. By preprocessing, the binarized defect image is achieved. In this procedure, Top-hit transform, adaptive thresholding, thinning and noise rejection are used. Especially, Top-hit transform using local min/max operation diminishes the effect of bad lighting. In feature extraction, geometric, moment and co-occurrence matrix features are calculated. For the defect classification, multilayer neural network is used. The proposed algorithm showed 15% error rate.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.1084-1089
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• 2004

This paper describes the improvement of web cache server by scoping in replacement algorithm of data which are collected from the clients. We have found that each replacement algorithm is suitable for each type of data in the web pages. Therefore, we introduce the mechanism to select the replacement algorithm depending on the size of data called the Replacement Algorithm Selection Mechanism (RASM). RASM allows the web cache server to have the suitable replacement algorithm for each type of data. As the result, the byte hit ratio of web cache server can be increased and the congestion in the network can be alleviated.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.296-296
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• 2016

ITO films doped with a small amount of high-permittivity materials not only retain the basic properties of ITO films but also improve some of their properties. We report the highly conductive and transparent (ITO:Zr) films with various substrate (RT to 300oC) temperatures on glass substrate for the HIT solar cell applications. We observed a decrease in sheet resistance from 36 to $11.8{\Omega}/{\Box}$ with the increasing substrate temperature from RT to 300oC, respectively. The ITO:Zr films showed also lowest resistivity of $1.38{\times}10-4{\Omega}.cm$ and high mobility of 42.37cm-3, respectively. The surface and grain boundaries are improved with the increase of substrate temperature as shown by SEM and AFM surface morphologies. The highly conductive and transparent ITO:Zr films were employed as front electrode in HIT solar cell and the best performance of device was found to be Voc = 710 mV, Jsc = 33.70 mA/cm2, FF = 0.742, ${\eta}=17.76%$ at the substrate temperature of $200^{\circ}C$.

• 대한통합의학회지
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• 제2권4호
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• pp.9-17
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• 2014

Purpose : The purpose of this study was to ascertain the effects of air-pressure cervical traction on the tension headache in the adults. Method : All subjects were treated with air-pressure cervical traction while 15 minutes a day, 3 times per week, for 4 weeks. The effects of air-pressure cervical traction were evaluated by HIT-6(headache impact test), VAS, and flexion, extension, left right flexion, left right rotation of cervical ROM. The measured data were analyzed by using repeated ANOVA. Especially in order to investigate the effect of air-pressure cervical traction. The comparison with among three measurement time. Results : The results of this study were as follows; 1) Prior and two weeks measurement did not show significant differences. The head forward posture than before the experiment, each experimental group was significantly increased(p<.05). 2) Prior and two weeks measurement did not show significant differences. The experimental group than ever cervical ROM of the movable range increased significantly(p<.05). 3) The experimental group was significantly lower than before the VAS(p<.05). 4) HIT score of the experimental group was significantly lower than before(p<.05). Conclusion : These findings suggest that air-pressure cervical traction had effect on the tension headache in the adults.