• 대한의용생체공학회:의공학회지
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• 제36권1호
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• pp.1-6
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• 2015

This study aims to design a monolayer cell adsorption apparatus that would help to produce high-quality slides for Liquid-Based Cytology (LBC) of an early cancer diagnosis for human bodies. The LBC collects exfoliated cells of human bodies and spreads the cells on the slides. Through processes of dyeing and cytological examination, the LBC screens for cancers in early stage. In this study, both of a cell suction module and a cell adsorption module, which are the key elements of the monolayer cell adsorption apparatus, were developed, and using those modules, the study set, first, conditions to help both GYN and NON-GYN apply principal cells without de-endothelialization before conducting its own analysis on the utility. As a results, for GYN, apparatus was determined to be able to produce high-quality slides under the condition of 4 and for NON-GYN, the apparatus would come up with other slides of high-quality under the condition of 2. The study carried out a repetitive test on selected conditions and proved 96% of the repetitive success rate. By the results of what has been learned so far, the study presents that the apparatus has a possibility to replace device from South Korea as one of those other currently-applied systems to run the LBC and that the system will also present a new paradigm for cancer diagnosis as it makes a contribution to the improvement in the LBC.

• International Journal of Quality Innovation
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• 제9권3호
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• pp.93-112
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• 2008

This study explores the influence of Taiwan's high-tech manufacturers' innovative strategy and innovation motivation concerning the implementation of innovative activities, as well as the influence of innovative activities implementation on business performance. The two intermediate variables, industry group and enterprise scale are also considered. Through a review of the relevant literature, a theoretical model of the influence relationship is developed, while an empirical analysis is simultaneously conducted on Taiwan's high-tech manufacturers. The research result shows that the internal driving force of innovative activities has a significant impact on the level of implementing technological innovative activities and cultural innovative activities. The external driving force of innovative activities has a significant impact on the level of implementing market innovative activities and management innovative activities. Companies adopting self-developed technology and purchased as well as self-developed technology strategies, perform better than those adopting purchased new technology or those with neither purchased nor self-developed technology strategies, at implementing technological innovative activities and cultural innovative activities. The level of implementing innovative activities has a significant influence on business performance (cost reduction and product/service differentiation). For the intermediate variables of "industry group" and "enterprise scale", it is proven in this study that they have no significant influence on the level of innovative activity implementation or business performance.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2006년도 춘계학술발표회 논문집(I)
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• pp.466-469
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• 2006

This paper presents the structural characteristics of slab-column connections by using nonlinear finite element analysis. FEA considering material non-linearity was performed to investigate average column strain, failure mode, principal stress distribution, and steel yielding conditions for various slab-column members. In addition, to investigate alternative methods for improving the strength of interior column-slab joints, some specimens were provided with different reinforcing types of high-strength concrete puddling, high-strength column longitudinal steels, dowel bars, and high-strength concrete core. To make certain of the reliability of the analytical program, analysis results for concrete material model developed and two specimens with and without puddling were compared with experimental results. It was found that providing the alternative reinforcing methods in the slab-column joint results in a significant improvement in performance. This includes an increase in the axial compressive strength, greater loading stiffness, and ductility.

• International Journal of Internet, Broadcasting and Communication
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• 제16권1호
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• pp.269-279
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• 2024

The study explores the evolving landscape of overseas expansion strategies by Korean corporations, focusing on recent geopolitical tensions, the COVID-19 pandemic, and disruptions in global supply chains. It emphasizes the challenges faced by industries producing high-value products and delves into the concept of "Friend-Shoring" policies in the United States, leading major Korean companies to invest in local semiconductor, battery, and automotive factories. Recognizing the potential fragmentation of Korea's manufacturing sector, the paper introduces the "Mother Factory" strategy as a policy initiative, inspired by Japan's model, to establish core production facilities domestically. The discussion unfolds by examining the cases of major companies in Japan and the United States, highlighting the need for Korea to adopt a mother factory strategy to mitigate risks associated with friend-shoring policies. Inspired by Intel's "Copy Exactly" approach, the paper proposes a Korean mother factory model integrating smart factory technology and digital twin systems. This strategic shift aims to enhance responsiveness to geopolitical challenges and fortify the competitiveness of Korean high-tech industries. Finally, the paper proposes a Korean Mother Factory based on smart factory concepts. The suggested model integrates smart factory technology and digital twin frameworks to enhance responsiveness and fortify competitiveness. In conclusion, the paper advocates for the adoption of a comprehensive Korean Mother Factory model to address contemporary challenges, foster advanced manufacturing, and ensure the sustainability and competitiveness of Korean high-tech industries in the global landscape. The proposed strategy aligns with the evolving dynamics of the manufacturing sector and emphasizes technological advancements, collaboration, and strategic realignment.

• 센서학회지
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• 제33권3호
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• pp.173-178
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• 2024

Development of pressure sensors for harsh environments with high pressure, humidity, and temperature is essential for many applications in the aerospace, marine, and automobile industries. However, existing materials such as polymers, adhesives, and semiconductors are not suitable for these conditions and require materials that are less sensitive to the external environment. This study proposed a pressure sensor that could withstand harsh environments and had high durability and precision. The sensor comprised a piezoresistor pattern and an insulating film directly formed on a stainless-steel membrane. To achieve the highest sensitivity, a pattern design method was proposed that considered the stress distribution in a circular membrane using finite element analysis. The manufacturing process involved depositing and etching a dielectric insulating film and metal piezoresistive material, resulting in a device with high linearity and slight hysteresis in the range of a maximum of 40 atm. The simplicity and effectiveness of this sensor render it a promising candidate for various applications in extreme environments.

• 동의생리병리학회지
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• 제32권6호
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• pp.384-395
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• 2018

The aim of this study was to investigate whether a novel formulation of an herbal extracts has an inhibitory effect on obesity. To determine its anti-obesity effects, we performed anti-obesity-related experiments in vitro and in vivo. Thus, our present study was carried out to evaluate the anti-obesity effect of herbal extracts using a high fat diet (HFD)-induced obese mouse model and 3T3-L1 adipose cells. The effects of each herbal extracts on lipid accumulation in 3T3-L1 cells were examined using Oil Red O staining. Results showed that treatment with each herbal extracts at $10{\sim}100{\mu}g/ml$ had no effect on cell morphology and viability. Without evidence of toxicity, herbal extracts treatment decreased lipid accumulation compared with the untreated adipocytes controls as shown by the lower absorbance of Oil Red O stain. Futhermore, compared with control-differentiated mature adipocytes, each herbal extracts significantly inhibited lipid accumulation in mature 3T3-L1 adipocytes. In the HFD-fed obese mice, body weight, liver weight and white adipose tissue weights were significantly reduced by mixture of herbal extracts administration in mouse skin. Futhermore, we found that mixture of herbal extracts administration suppressed serum triglyceride (TG), and total cholesterol (TCHO) in HFD-induced obese mouse model. The mixture of herbal extracts of permeability was estimated by measuring the transepithelial electrical resistance (TEER) value in pig skin. The optimized formulations of herbal extracts (Test 3 formulation) showed skin permeation. However, test 1 formulation containing essential oil as enhancer showed maximum skin permeation. After confirming the enhanced skin permeability, in vivo studies were performed to assess whether skin irritation potential on the basis of a primary irritation index (PII) in rabbit skin. Reactions were scored for erythema/edema reactions at 24 h, 48 h and 72 h post-application. It was concluded that the test 1 formulation was not irritation (PII = 0). The present study suggests that the test 1 formulation might be of therapeutic interest with respect to the treatment of obesity.

• Journal of the Korean Wood Science and Technology
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• 제29권4호
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• pp.9-15
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• 2001

본 연구는 $100^{\circ}C$ 이상의 고온영역에서 증기처리에 의한 소나무(Pinus densiflora)재와 라디아타소나무(Pinus radiata)재의 전단강도를 조사하였다. 본 연구에서 사용한 열처리 조건은 온도조건 $100^{\circ}C$부터 $200^{\circ}C$까지 $20^{\circ}C$ 간격으로 6조건과 시간조건 5, 10, 20, 30분의 4조건이었으며, 폭쇄처리기를 사용하였다. 고온에서 증기처리에 의해 목재구성요소의 감소가 전단강도의 감소로 나타나고 목질재료의 광범위한 가소화를 진행시키는 것으로 판단된다. 목재의 전단강도는 증기처리시간에 따라서 점차적으로 감소한다는 것을 알 수 있었다. 10분 이상의 증기처리시간일 경우 온도가 올라갈수록 전단강도의 감소가 눈에 띄게 커졌다. 고온에서 증기처리에 의한 연화는 목재가공성 향상에 필요하다고 생각된다.

• E2M - 전기 전자와 첨단 소재
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• 제15권9호
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• pp.10-14
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• 2002

Plasma processing plays a significant role in semiconductor devices technology. Development of new plasma systems, such as high-density plasma reactors, required development of plasma theory to understand a whole process mechanism and to be able to explain and to predict processing results. A most important task in this way is to establish interconnections between input process parameters (working gas, pressure flow rate input power density) and a various plasma subsystems (electron gas, volume and heterogeneous gas chemistry, transport), which are closely connected one with other. It will allow select optimal ways for processes optimizations.

• 한국재료학회지
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• 제20권11호
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• pp.575-580
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• 2010

The microstructure and positive temperature coefficient of resistivity (PTCR) characteristics of 0.1 mol%$Na_2Ti_6O_{13}$ doped $0.94BaTiO_3-0.06(Bi_{0.5}Na_{0.5})TiO_3$ (BBNT-NT001) ceramics sintered at various temperatures from $1200^{\circ}C$ to $1350^{\circ}C$ were investigated in order to develop eco-friendly PTCR thermistors with a high Curie temperature ($T_C$). Resulting thermistors showed a perovskite structure with a tetragonal symmetry. When sintered at $1200^{\circ}C$, the specimen had a uniform microstructure with small grains. However, abnormally grown grains started to appear at $1250^{\circ}C$ and a homogeneous microstructure with large grains was exhibited when the sintering temperature reached $1325^{\circ}C$. When the temperature exceeded $1325^{\circ}C$, the grain growth was inhibited due to the numerous nucleation sites generated at the extremely high temperature. It is considered that $Na_2Ti_6O_{13}$ is responsible for the grain growth of the $0.94BaTiO_3-0.06(Bi_{0.5}Na_{0.5})TiO_3$) ceramics by forming a liquid phase during the sintering at around $1300^{\circ}C$. The grain growth of the BBNT-NT001 ceramics was significantly correlated with a decrease of resistivity. All the specimens were observed to have PTCR characteristics except for the sample sintered at $1200^{\circ}C$. The BBNT-NT001 ceramics had significantly decreased $\tilde{n}_{rt}$ and increased resistivity jump with increasing sintering temperature at from $1200^{\circ}C$ to $1325^{\circ}C$. Especially, the BBNT-NT001 ceramics sintered at $1325^{\circ}C$ exhibited superior PTCR characteristics of low resistivity at room temperature ($122\;{\Omega}{\cdot}cm$), high resistivity jump ($1.28{\times}10^4$), high resistivity temperature factor (20.4%/$^{\circ}C$), and a high Tc of $157.9^{\circ}C$.

• 한국건설순환자원학회논문집
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• 제3권3호
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• pp.237-243
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• 2015

본 연구에서는 알칼리 활성화 슬래그 결합재의 반응성을 정량적으로 살펴보기 위해 미소수화열을 분석을 수행하였다. 알칼리 활성화 슬래그 결합재의 반응성 및 작업성 확보를 위해 다양한 알칼리 자극제의 종류 및 농도에 대해서 실험을 수행하였다. 알칼리 자극제 및 $SO_3$ 질량비를 변화하면서 미소수화열을 측정하였으며, 응결시간 제어를 위해 sodium tripolyphosphate ($Na_2P_3O_{10}$)와 hydrated sodium borate ($Na_2B_4O_710H_2O$)를 적용하였다. 그 결과, 알칼리 활성화 슬래그 결합재는 알칼리 활성에 의해 calcium silicate hydrate(C-S-H)를 촉진하는데 4~5% 농도의 알칼리가 필요한 것으로 나타났으며, $SO_3$ 함량이 높아질수록 누적 발열량이 작아지면서 전반적으로 발열이 지연되는 것으로 나타났다. 또한, 응결 지연제로서 hydrated sodium borate를 사용하였을 경우 발열을 억제하여 지연된 효과를 나타내며, 전체적인 누적 발열을 지연시키는 효과를 보이는 것을 확인할 수 있었다.