• 대한종양외과학회지
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• 제14권2호
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• pp.116-119
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• 2018

Purpose: This study assessed the effect of chemotherapy over stage II colon cancer in terms of presence of high-risk factors. Methods: Data were retrospectively reviewed for 364 patients with stage II colon cancer who underwent curative surgery between January 2007 and December 2012. High-risk factors of stage II colon cancer were examined, and the overall survival (OS) rates were analyzed. Survival benefit of adjuvant chemotherapy was also analyzed. Results: One hundred and fifteen cases had exclusively single high-risk factor and 194 cases were negative for high-risk factors. Postoperative chemotherapy was performed in 262 of 364 patients (72.0%). The 5-year OS was 79.4% and 86.6% for patients without adjuvant chemotherapy and those with chemotherapy, respectively. The 5-year OS was 88.2% and 83.3% for patients having exclusively single high-risk factor with adjuvant chemotherapy and those without chemotherapy, respectively. Conclusion: Adjuvant chemotherapy for patients with stage II colon cancer having exclusively single high-risk factor could be omitted, weighing up the survival benefit and side effect of chemotherapy.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3455-3460
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• 2012

Objectives: To report the prevalence of atypical squamous cells of undetermined significance and atypical squamous cells-cannot exclude high squamous intraepithelial lesions and to determine the possible association of Pap test results with high-risk human papillomavirus and high squamous intraepithelial lesions in women from Duhok, Iraq. Design: A prospective, observational study was conducted between January 2005 and December 2011. Overall, 596 women with a cervicovaginal Pap test showing atypical squamous cells of undetermined significance and 93 atypical squamous cells-cannot exclude high squamous intraepithelial lesion for whom pathologic follow-up was available were studied. Follow-up consisted of repeat cytology, colposcopy and histology. High risk human papillomavirus DNA testing was performed on exfoliated cervical cells from 106 women, using conventional PCR after at least 36 months from the initial Pap smear. Results: Significantly high proportions of both atypical squamous cells of undetermined significance (87.9%) and atypical squamous cells-cannot exclude high squamous intraepithelial lesion (62.4%) demonstrated no significant lesion on subsequent follow up. Low squamous intraepithelial lesions were observed in 1.7% of cases of atypical squamous cells of undetermined significance and in 5.4% of atypical squamous cells-cannot exclude high squamous intraepithelial lesion. High squamous intraepithelial lesion was demonstrated in 0.8% and 16.1% respectively. In the latter there was also one case of invasive carcinoma. High-risk HPV DNA was demonstrated in 40% of atypical squamous cells of undetermined significance and 57.1% of atypical squamous cells-cannot exclude high squamous intraepithelial lesions. Conclusions: Since both atypical squamous cells of undetermined significance and atypical squamous cells-cannot exclude high squamous intraepithelial lesion identify patients who are at an increased risk for the development of high squamous intraepithelial lesions and a considerable percentage harbor high risk-HPV, both should be retained as diagnostic categories and patients warrant a diligent follow up and testing for high risk-HPV DNA. Colposcopic evaluation and biopsy, when indicated, are a must.

• 한국산학기술학회논문지
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• 제22권5호
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• pp.51-59
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• 2021

본 연구는 여성의 고위험 음주에 관한 영향요인을 분석하고자 시도되었다. 본 연구는 제7기 국민건강영양조사 자료를 활용하였으며, 연구대상자는 만 19세 이상 여성 3,619명이었다. 자료 분석을 위해 대상자를 국민건강영양조사의 고위험 음주율 지표에 따라 일반음주여성과 고위험음주여성으로 구분하여 인구사회학적 특성, 신체건강관련 특성, 정신건강관련특성의 차이 및 고위험음주 영향요인을 파악하였다. 자료 분석은 IBM SPSS 25.0 프로그램을 이용하여 복합표본설계를 적용하였다. 연구결과, 우리나라 여성의 고위험 음주율은 8.8%로 나타났고, 고위험 음주의 영향요인은 20대부터 40대까지의 낮은 연령, 흡연을 하는 경우, 우울감을 경험한 경우로 나타났다. 특히 흡연과 우울감 여부는 고위험 음주에 대한 위험도를 각 4.5배[(95% confidence interval(CI)=2.804-7.372, p<0.001)], 7.0배[(95% confidence interval(CI)=2.918-16.855, p<0.001)] 높이는 것으로 나타나 중요한 위험요인인 것으로 분석되었다. 또한, 고위험 음주여성의 음주시작연령이 15세에서 19세에서 높은 비율로 나타나 청소년기와 초기 성년기 여성 대상의 음주 교육 프로그램의 개발 및 시행이 시급함을 시사하고 있다. 상기와 같은 본 연구의 결과는 여성 고위험 음주율을 낮추기 위한 보건정책 및 건강증진 프로그램에 활용 될 수 있을 것으로 기대된다.

• 한국도로학회논문집
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• 제15권1호
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• pp.127-134
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• 2013

PURPOSES: Speeding is often the primary contributor to fatal crashes. Surprisingly, driving behaviors are indirectly affected by personal factors such as law-abidance, risk sensitivity, and situational adaptability. This research aims to verify the effectiveness of pavement markings at reducing the speeds of high-risk drivers. The purpose of this study is to establish how drivers (including law-abiding or law-breaking, high-risk or low-risk) react to different pavement markings in a driving simulator. METHODS: The five different pavement markings were selected from markings used in other nations. The forty-two drivers were then surveyed, via questionnaires, and placed into the corresponding groups. Finally, statistical analysis was conducted to determine the extent of speed reduction for each pavement marking. RESULTS: Higher speeds were linked to the high-risk drivers. Furthermore, after analysis of the mean difference of average speeds by pavement marking, it was determined that Dragon's Teeth had the greatest speed reducing effect on these drivers. CONCLUSIONS: Perceptual countermeasures are unlikely to strongly affect high-risk drivers' perception of speed on the curves. This statistically demonstrates that Dragon's Teeth have a subtle effect on reducing speeds in the driving simulator. This study's significance lies in the improved understanding of high-risk drivers in terms of road facilities. It approaches the effects of various patterns of pavement markings for high-risk drivers.

• Nutrition Research and Practice
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• 제18권4호
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• pp.554-566
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• 2024

BACKGROUND/OBJECTIVES: Urban-rural inequities in health and mortality exist in Korea, a highly centralized developed country. The potential impact of multiple health-related lifestyle behaviors on mortality and difference between urban and rural areas is not fully understood. This study aimed to investigate the effect of high-risk health behaviors on all-cause mortality among residents living in urban and rural in Korea. SUBJECTS/METHODS: Cross-sectional analyses were conducted on 8,298 adults aged 40 yrs and older from the Korea National Health and Nutrition Examination Survey 2013-2015. High-risk behaviors were defined as having poor diet quality, current smoking, high-risk drinking, or insufficient physical activity. Mortality status was linked to the Cause of Death data followed up to December 31, 2019. The associations between all-cause mortality and high-risk behaviors were evaluated using Cox proportional hazard regression models adjusted for age, sex, education, income, and survey year. Population attributable fractions (PAFs) were calculated, and effect modification analysis was conducted. Participants were stratified by residential area (urban or rural). RESULTS: During the follow-up (median: 5.4 yrs), 313 deaths occurred. A higher proportion of rural residents than urban residents engaged in multiple high-risk behaviors (28.9% vs. 22.6%; P < 0.0001). As individual factors, a greater risk of mortality was associated with poor diet quality, current smoking, and inadequate physical activity, and these tendencies persisted in rural residents, especially for diet quality. Multiple high-risk behaviors were positively associated with a higher risk of mortality in Koreans living in urban and rural areas. PAF (95% confidence interval) was 18.5% (7.35-27.9%) and 29.8% (16.1-40.2%) in urban and rural residents, respectively. No additive or multiplicative effect of the region was observed. CONCLUSION: The higher prevalence of multiple high-risk lifestyle behaviors in rural residents may explain the higher mortality in rural areas compared to urban areas. Comprehensive public health policies to improve health-related behaviors in rural populations may be needed.

• 대한간호학회지
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• 제35권8호
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• pp.1500-1507
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• 2005

Purpose. The purpose of this study was to identify subgroups of the physical and behavioral risk profiles for cardiovascular disease among industrial workers, and to examine predicting factors for the subgroups. Sample and Method. Health records of 2,616 male and female workers aged 19-56 years who were employed in an airplane manufacturing industry were analyzed. Data were analyzed using the Latent class cluster analysis. Results. Four different clusters (two high-risk groups, one low-risk group, and one normal group) were found and these clusters were significantly different by age, gender, and work type (p < .05 ). The two high-risk groups had higher chances of drinking alcohol, elevated BMI, FBS, total cholesterol, having hypertension, and were significantly older, and had relatively high chances of being day workers rather than other groups. The low-risk group had higher chances of drinking alcohol, higher BMI and total cholesterols compared to normal group, and highest portions of current smokers and shift workers in the four clusters and their mean BP was within prehypertension criteria. Conclusion. Industrial nurses should guide the lifestyle behaviors and risk factors of the high risk groups for CVD and need to intervene early for behavioral change for the low-risk group who are young and shift workers. Age, and work environment should be considered in planning for targeted preventive interventions for industrial workers.

• 한국안전학회지
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• 제31권6호
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• pp.105-112
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• 2016

The current study examined the relationships between disaster victims' post-trauma risk and posttraumatic growth, and the mediational role of social support for this relationships. In addition, we tested the hypothesis that income status would moderate the relationship between post-trauma risk and subjective well-being. Two hundred disaster victims completed Post-trauma Risk Checklist (PRC), Posttraumatic growth scale, Social support scale and Concise Measure of Subjective Well-Being (COMOSWB) as well as questions about their demographic characteristics. Results showed that those with high post-trauma risk demonstrated significantly higher levels of posttraumatic growth as compared to those with low post-trauma risk and social support partially mediated this relationship. Also, high levels of post-trauma risk predicted low levels of recent subjective well-being. Participants with high income obtained higher subjective well-being than did those with low income among high post-trauma risk groups. Implications for post-trauma risk and posttraumatic growth are discussed.

• 복식
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• 제53권8호
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• pp.149-158
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• 2003

The purpose of the present study was to investigate the use level of display and perceived risk of high school girls according to their attitudes toward fashion. Data were collected through self-administered questionnaires and analyzed by descriptive statistics, $x^2$, ANOVA, and Duncan test. The sample consisted of 390 students at four girls' high schools located in Seoul. The results are as follows : 1. Based on the attitudes toward fashion, respondents were classified into 3 groups, fashion-oriented, fashion-conformed, fashion-retarded. No differences were found in fashion attitudes among and between the groups by residing place. The group having higher interest in fashion spent more expenditure for apparels, and showed the higher interest in display, and highly regarded the needs of display. 2. The more fashion-oriented group showed higher degree of risk perceiving. Especially, they perceived psychological risk, fashionability risk, and social risk highly. And all the three groups perceived opportunity risk most. 3. In general, those who are more sensitive to fashion showed more positive attitude of risk reduction activities.

• Journal of Korean Neurosurgical Society
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• 제64권2호
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• pp.189-197
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• 2021

Objective : This study aims to investigate the relationship between aneurysm wall enhancement and clinical rupture risks based on the magnetic resonance vessel wall imaging (MR-VWI) quantitative methods. Methods : One hundred and eight patients with 127 unruptured aneurysms were prospectively enrolled from Feburary 2016 to October 2017. Aneurysms were divided into high risk (≥10) and intermediate-low risk group (<10) according to the PHASES (Population, Hypertension, Age, Size of aneurysm, Earlier SAH history from another aneurysm, Site of aneurysm) scores. Clinical risk factors, aneurysm morphology, and wall enhancement index (WEI) calculated using 3D MR-VWI were analyzed and compared. Results : In comparison of high-risk and intermediated-low risk groups, univariate analysis showed that neck width (4.5±3.3 mm vs. 3.4±1.7 mm, p=0.002), the presence of wall enhancement (100.0% vs. 62.9%, p<0.001), and WEI (1.6±0.6 vs. 0.8±0.8, p<0.001) were significantly associated with high rupture risk. Multivariate regression analysis revealed that WEI was the most important factor in predicting high rupture risk (odds ratio, 2.6; 95% confidence interval, 1.4-4.9; p=0.002). The receiver operating characteristic (ROC) curve analysis can efficiently differentiate higher risk aneurysms (area under the curve, 0.780; p<0.001) which have a reliable WEI cutoff value (1.04; sensitivity, 0.833; specificity, 0.67) predictive of high rupture risk. Conclusion : Aneurysms with higher rupture risk based on PHASES score demonstrate increased neck width, wall enhancement, and the enhancement intensity. Higher WEI in unruptured aneurysms has a predictive value for increased rupture risk.

• Nutrition Research and Practice
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• 제16권3호
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• pp.392-404
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• 2022

BACKGROUND/OBJECTIVES: Numerous studies have examined the relationship between drinking behaviors and metabolic syndrome (MetS) for adults, but these include very few studies for young adults. This study therefore undertook to investigate the association between drinking behaviors and components of MetS among adult drinkers aged 20-30 years. SUBJECTS/METHODS: Using the 2016-2018 Korea National Health and Nutrition Examination Survey data, drinking behaviors of adults in the age group 20-30 years were divided into 4 groups: 1) group A, good drinking habits; 2) group B, frequent binge drinking but not frequent drinking; 3) group C, frequent drinking but not frequent binge drinking; 4) group D, frequent drinking and binge drinking. The association between MetS components and drinking behaviors was analyzed by applying multiple logistic regression analysis. RESULTS: We determined the prevalence risk compared to group A. In men, the prevalence risk of high triglyceride (TG) increased 2.051-fold in group C and 1.965-fold in group D. Moreover, in group D, the prevalence risk of low high density lipoprotein cholesterol (HDL-C) increased 0.668-fold, high blood pressure (BP) increased 2.147-fold, and MetS increased 1.567-fold. In women, there was an increased prevalence risk of low HDL-C (0.353-fold) and MetS (3.438-fold) in group C, whereas group D showed increased prevalence risk of abdominal obesity (2.959-fold), high TG (1.824-fold, and low HDL-C (0.424-fold). CONCLUSIONS: Our study indicates that frequent drinking increases the risk of high TG, whereas frequent and binge drinking increases the risk of high TG, low HDL-C, high BP, and prevalence of MetS in men. In women, frequent drinking without binge drinking increases the risk of low HDL-C and MetS, whereas frequent and binge drinking increases the risk of abdominal obesity, high TG, and low HDL-C. We propose that improvements in the drinking behaviors can reduce the prevalence of MetS.