• 제목/요약/키워드: High Yield

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The Development of Radiopharmaceutical Synthesizer and its FDG Synthesis Verification

  • Jong Min Kim;Il Koo Cheong;Chan Soo Park;Hee Seup Kil;Cheol Soo Lee
    • 대한방사성의약품학회지
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    • 제8권2호
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    • pp.87-93
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    • 2022
  • [18F]FDG is known as the most widely used radiopharmaceutical in the imaging field of nuclear medicine worldwide. With the introduction of PET equipment, the demand for [18F]FDG has increased and the production volume has also increased. However, in order to increase production, the use of 18F radioisotope must be increased or [18F]FDG must be synthesized in high yield. Therefore, in order to meet the high yield and purity of radiopharmaceuticals, a radiopharmaceutical automatic synthesizer was required. As the use of [18F]FDG increased, automated synthesizer manufacturers supplied various types of radiopharmaceutical automated synthesizers to the market. In this study, we developed a commercialized [18F]FDG radiopharmaceutical automatic synthesizer (sCUBE FDG) using a disposable cassette type that complies with GMP developed by FutureChem, a leading radiopharmaceutical company. We used sCUBE FDG to verify the production process, radiopharmaceutical's quality (radiochemical purity, etc.), and radiochemical yield of [18F]FDG. As a result of optimizing the automatic synthesis process and synthesizing a total of 30 times, the production time was 35 ± 3 minutes and the average production yield was 65.6%.

Optimal Nitrogen Fertilizer Application Method for High Quality Bread Wheat Production

  • Han-yong Jeong;Yulim Kim;Chuloh Cho;Jinhee Park;Chon-Sik Kang;Jong-Min Ko;Jiyoung Shon
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 2022년도 추계학술대회
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    • pp.61-61
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    • 2022
  • For high quality bread wheat production in Korea, it is necessary to develop optimal nitrogen (N) fertilizer methods. For optimal N fertilizer, we evaluated the alteration of growth, yield, yield components and end-use qualities according to the treatment of N fertilizer amounts and timings at heading stages. Growth, yield, yield components, and end-use quality weren't altered by various timings of N fertilizer treatment conditions whereas, 1,000 grain weight and lodging degree was increased by increasing amounts of N fertilizer treatment conditions at 7 days after heading (7 DAH). Especially, lodging degree was significantly increased by 6kg/10a of N fertilizer treatment conditions at 7 DAH. The flour protein contents increased by various amounts of N fertilizer treatment conditions. However, SDS-sedimentation and bread loaf volumes were decreased by exceeding 6kg/10a of N fertilizer treatment conditions at 7 DAH. When considering the quality of bread, 6kg/10a N fertilizer treatment is best, but 3kg/10a N fertilizer treatment is more suitable for both quality and lodging at 7 DAH. Therefore, it is preferable to fertilize 3kg/10a of nitrogen at 7 DAH in addition to standard fertilizer when cultivate bread wheat.

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조숙 다수 내재해성 호밀 품종 "참그린" (A Rye Cultivar "Charmgreen", Early-heading, High Forage Yield Potential, and Resistance to Stresses)

  • 한옥규;김대욱
    • 한국초지조사료학회지
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    • 제44권1호
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    • pp.14-19
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    • 2024
  • "Chamgreen" was a domestically developed rye (Secale cereal L.) cultivar in South Korea, known for its quick heading, cold resistance, and abundant yield of forage. The heading date of cv. 'Chamgreen' averaged April 17th, which was 4 days earlier than the standard cv. 'Gogu'. In the early harvesting stage, the plant height reached an average of 119 cm, 7 cm taller than the standard cv. 'Gogu', and the number of spikes per m2 was 865, slightly less than cv. 'Gogu's 897. Resistance to cold and powdery mildow remained consistent across four regions nationwide over three years, with an average rating of 0, matching cv. 'Gogu'. Lodging resistance was also rated at 2, equivalent to cv. 'Gogu'. The dry matter yield of cv. 'Chamgreen' was 9.1 tons per hectare, 15% higher than cv. 'Gogu's 7.9 tons. Although the protein content in cv. 'Chamgreen' was 13.5%, 1.6% lower than cv. 'Gogu', the total digestible nutrients (TDN) content was 5.81 tons per hectare, 20% higher than cv. 'Gogu'. Due to its strong cold resistance, cv. 'Chamgreen' allows for winter cultivation through double cropping and rotation systems in various regions across the country.

Efficacy of Cyanobacterial Biofertilizer (CBB) on Leaf Yield and Quality of Mulberry and its Impact on Silkworm Cocoon Characters

  • Dasappa D.M. Ram Rao;Ramaswamy S.N.
    • International Journal of Industrial Entomology and Biomaterials
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    • 제13권1호
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    • pp.15-22
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    • 2006
  • An experiment was conducted to study the efficiency of cyanobacterial biofertilizer (CBB) with chemical (NPK) fertilizer on quantitative and qualitative characters of mulberry variety Kanva-2. Their influences on silkworm growth and cocoon characters were also studied. Ten different CBB and NPK fertilizer treatments were given to 5000 plants of established mulberry garden. Treatments were of four types viz., (i) T1 to T7: single and combination dose of CBB+50% NPK (ii) T8: combination dose of CBB + 25%NPK, (iii) T9: CBB only and (iv) T10: control-l00% NPK. Soil pH decreased and nutrients status increased in CBB (T1- T9) treated plots. Average of ten crops data on quantitative traits revealed that T7 (CBB [N. muscorum (1.0 g), A. variahilis (1.0) and S. millei (1.0 g)] + 50% NPK) was very effective in improving growth parameters. Leaf yield was also found high in treatment T7 (32.12 tons/ha/yr.) followed by T10 (31.17 tons/ha/yr.) and T8 (27.67 tons/ha/yr.). Leaf quality characters were found high in T7 and low in T9. Most of the quality traits in T7 are on par with control no. The results revealed that reduction in the dose of chemical fertilizers in T7 did not affect the leaf yield and leaf quality traits of mulberry. This clearly indicates that the efficiency of CBB (T7) provides nitrogen, increases essential nutrients available in soil, maintain soil pH and supply growth substances required for the improvement of leaf yield and leaf quality of mulberry. Bioassay study also revealed no significant difference in silkworm growth and cocoon characters between treatments T7 and T10. Economics calculated revealed that T7 is highly economical and beneficial over T10 by gaining an amount of Rs. 660/-/acre/crop. Thus, treatment T7 containing N. muscorum (1.0 g), A. variahilis (1.0 g) and S. millei (1.0 g) + 50% NPK fertilizers can be recommended to sericulturists mainly to reduce the use of NPK fertilizers, by saving 50% of its cost and to improve soil fertility conditions, which in turn improves leaf yield and quality of mulberry.

비음과 질소시비가 Orchargrass의 건물생산에 미치는 영향 (the Effects of Shade and N Fertilization on the Dry Matter Production of Orchargrass)

  • 이주삼
    • 한국초지조사료학회지
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    • 제11권3호
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    • pp.175-181
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    • 1991
  • The purpose of this experiment was to evaluate the effects of shade and levels of N fertilization on the dry matter yield and chemical compositions of orchardgrass grown under floor of chestnut tree. Shading conditions consist of $S_0$, (full light), $S_1$, (about 6OC4 shade) and $S_2$, (about 70% shade). And, nitrogen fertilizer was applied at 3 levels, O($N_0$), 12($N_1$), and 30($N_2$) kg per 10a, respectively. The results are may be summarized as follows: 1. Maximum total dry matter yield of $S_0$, was obtained about 1.28 ton/lOa at $N_2$, level. But, total dry matter yields of N levels in $S_1$, and $S_2$, were decreased about 42-45% compared with $S_0$. 2. The response of the dry matter yield to N fertilization were differences between shading and levels of N. Thus, the dry matter yield of $S_1$, increased almost linear up to about 30 kg/l0a level, while the dry matter yield of S, was increased slightly up to 30 kgIl0a. But. $S_2$, was increased up to 12 kg/lOa and then decreased slightly with N fertilization over the 12 kg/l0a. 3. Average increase in total dry matter yield to N fertilization were 23.85 kg, 7.97 kg and 5.08 kg DM for $S_0$, $S_1$, and $S_2$, respectively. 4. The level of 12 kg N/lOa is the limiting N level to obtain dry matter production under 60-709 shading conditions. 5. The contents of crude protein arid nitrate nitrogen were increased with shading and incremental N fertilization up to 30 kg/l0a. But, water soluble carbohydrate content was decreased greatly with high shading and high levels of N. 6. Nitrate nitrogen content indicated highly significant positive correlation with crude protein, but significant negative correlation with water soluble carbohydrate content. 7. At 30 kg N level with $S_1$, was necessary to exceed the potentially toxic nitrate nitrogen level of 0.20%.

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간척지 재배 벼 품종의 수량과 품질과의 관계 (Relationship between Yield and Quality of Rice Varieties Grown in Reclaimed Saline Paddy Field)

  • 채제천;정명식;전대경;손용만
    • 한국작물학회지
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    • 제47권3호
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    • pp.259-262
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    • 2002
  • 간척지 논에서 고품질 쌀 생산을 위한 기초 자료를 얻고자 2001년 농업기반공사 김포간척지에서 9개 벼 품종의 수량과 단백질 함량 및 식미치의 관계를 검토한 결과는 다음과 같다. 1. 쌀 수량은 식미계에 의한 식미치와 고도로 유의한 부상관(r=-0.49$^{**}$ )을 나타내었다. 수량이 낮은 수라벼의 식미치가 가장 높았고 수량이 높은 대안벼와 진품벼는 식미치가 가장 낮았다. 2. 간척지 재배 백미의 단백질 함량은 모든 품종이 7.5% 이상으로 상당히 높은 편이었는데 이는 시비와 관개용수에서 많은 질소질비료가 공급된 결과로 보여졌다. 3. 김포간척지에 적합한 벼 품종은 수량성 면에서는 대안벼, 진품벼, 신동진벼이나 품질을 고려한다면 단백질 함량이 낮고 식미치가 높은 광안벼, 수라벼, 남평벼가 적합하다고 사료되었다.

열간 단조 제품 A694-F70 플랜지의 항복강도 향상 (Improving Yield Strength of A694-F70 Flange Manufactured by Hot Forging Process)

  • 우타관;이현우;전충환;장영준;김철
    • Journal of Advanced Marine Engineering and Technology
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    • 제34권8호
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    • pp.1068-1073
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    • 2010
  • 용접 넥 플랜지는 파이프간의 상호연결에 널리 사용되고 있다. 이 플랜지는 열간 단조 공정으로 제작되며, 심해에서 고압이 요구되는 분야에 사용되는 경우 플랜지 기저부 및 목 부분에 높은 항복강도가 요구된다. 일반적으로 항복강도 향상을 위해 탄소함유량을 높이면 고 강도를 얻을 수 있으나, 용접이 요구되는 제품의 특성상 탄소함유량을 최대 0.47로 제한함으로써 고용체 강화에 의한 강도 향상에는 한계가 있다. 이러한 경우 탄소 함유량의 변화 없이 강도를 향상시킬 수 있는 결정립 미세화 강화를 이용하여 제품의 항복강도를 향상시킬 수 있다. 본 연구에서는 다구찌 기법을 통해 최적의 결정립 미세화를 위한 단조공정을 제시하고 타당성을 검토하기 위해 유한요소해석을 수행하였다.

조.만생 Orchargrass 품종의 생육특성과 수량성 및 사료가치 비교 연구 (Growth Characteristics , Yield , and Nutritive Value of Early- and Late Maturing Cultivars of Orchargrass ( Dactylis glomerate L. ))

  • 서성;신동은;정의수;강우성;양종성
    • 한국초지조사료학회지
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    • 제17권1호
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    • pp.27-34
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    • 1997
  • This experiment was carried out to determine growth characteristics, dry matter (DM) yield, seasonal yield distribution and nutritive value of early- and late maturity orchardgrass, 1990 to 1992. The cultivars used in this study were Potomac, Hallmark (early maturing cultivar) and Lidacta, Rancho (late maturing cultivar), and a mixture plot (Potomac 25% + Hallmark 25% + Lidacta 25% + Rancho 25%) was involved. The seeding rate was 20 kgha in all treatments. Plant height of Potomac and Hallmark was longer than that of Lidacta and Rancho. The dates of initial heading and 50% heading of early maturing cultivars (Apr. 30 and May 10) were 10 days earlier than those of late matuing cultivars. Potomac and Hallmark were upright, and Lidacta and Rancho were semi-upright type, and severe disease and weeds (30 ~ 40%) were observed at Lidacta plot. On an average of three years, the DM yields of Potomac (10,549 kglna), Hallmark (10,435 kg) and mixture (10,356 kg) were significantly (P<0.05) higher than those of Rancho (9,457 kg) and Lidacta (8,218 kg). However, seasonal yield distribution of late maturing cultivars was better than that of early maturing cultivars. The contents of crude protein, crude fat, crude fiber, nitrogen %ee extract, aude ash, neutral detergent fiber, P, K, Ca, and Mg were not significantly different between cultivars, but higher aude protein yield was found at Potomac, Hallmark and mixture plots. Based on the above results, it may be concluded that early maturing cultivars for high productivity, late maturing cultivars for seasonal yield distribution, and seeding of mixture andlor separation of early- and late maturing cultivars are recommended. Also Lidacta was a not promising cultivar due to low productivity, severe disease, and high weeds development.

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High Temperature Creep Properties of Al-Al4C3-Al2O3 Alloy by Mechanical Alloying

  • Han, Chang-Suk;Seo, Han-Byeol
    • 한국재료학회지
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    • 제26권7호
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    • pp.370-375
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    • 2016
  • Tensile tests and creep tests were carried out at high temperatures on an Al-$Al_4C_3$ alloy prepared by mechanical alloying technique. The material contains about 2.0% carbon and 0.9% oxygen in mass percent, and the volume fractions of $Al_4C_3$ and $Al_2O_3$ particles are estimated at 7.4 and 1.4%, respectively, from the chemical composition. Minimum creep rate decreased steeply near two critical stresses, ${\sigma}_{cl}$ (the lower critical stress) and ${\sigma}_{cu}$ (the upper critical stress), with decreasing applied stress at temperatures below 723 K. Instantaneous plastic strain was observed in creep tests above a critical stress, ${\sigma}_{ci}$, at each test temperature. ${\sigma}_{cu}$ and ${\sigma}_{ci}$ were fairly close to the 0.2% proof stress obtained by tensile tests at each test temperature. It is thought that ${\sigma}_{cl}$ and ${\sigma}_{cu}$ correspond to the microscopic yield stress and the macroscopic yield stress, respectively. The lower critical stress corresponds to the local yield stress needed for dislocations to move in the soft region within subgrains. The creep strain in the low stress range below 723 K arises mainly from the local deformation of the soft region. The upper critical stress is equivalent to the macroscopic yield stress necessary for dislocations within subgrains or in subboundaries; this stress can extensively move beyond subboundaries under a stress above the critical point to yield a macroscopic deformation. At higher temperatures above 773 K, the influence of the diffusional creep increases and the stress exponent of the creep rate decreases.

SM570TMC 강재의 재료특성에 관한 연구 (A Study on the Materials Characteristics of SM570TMC Plates)

  • 임성우;김요숙;장인화
    • 한국강구조학회 논문집
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    • 제17권3호통권76호
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    • pp.365-373
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    • 2005
  • 건축물이 고층이 될 수록 고강도 강재의 사용요구가 증대된다. 그러나 고강도 강재는 일반 강재와는 전혀 다른 기계적 특성을 갖고 있다. 고강도 강재를 건축구조물에 적용하기 위해서는 비탄성 영역에서의 거동이 일반 강재와 동등한가를 확인해야 한다. 본 연구에서는 최근 국내에서 개발된 SM570TMC 강재를 건축구조용으로 사용하기 위해서 기계적 성질 및 용접부 특성을 평가하였다. 연속항복현상을 보이는 SM570TMC 강재는 판두께가 증대되어도 강도저감이 발생되지 않았으며, 최소 항복강도가 440MPa로 나타났다. 또한 판두께 방향으로 균일한 경도분포를 보였다. -5oC에서의 Charpy 충격값도 충분한 인성을 보였다. 용접성과 관련있는 탄소당량은 기존 건축구조용 강재보다 훨씬 낮았으며, 용접부 특성도 우수하였다.