• Title/Summary/Keyword: Hi-tech

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Study on Structure Design of High-Stiffness for Multi-Function Automatic Lathe Bed (다기능 자동 선반 베드의 고강성 구조설계에 관한 연구)

  • Jo, Eun-Jeong;Lee, Yun-Chul;An, Jong-Bok;Lee, Yeong-Sik;Lee, Jae-Kwon;Kim, Kwang-Sun
    • Journal of the Semiconductor & Display Technology
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    • v.18 no.1
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    • pp.112-116
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    • 2019
  • This study was carried out by structural analysis using finite element method for designing high rigidity structure of multi - functional automatic lathe bed. As a result of comparison, it was confirmed that the weight was designed to be higher than the maximum deformation amount. The shape and dimensions of the main pillars and walls of the bed were changed to derive the most suitable design for the multifunction automatic lathe bed. A model of structural design was derived with the goal of minimizing the maximum deformation amount of $20{\mu}m$ or less and the weight of the bed. As a result of applying the derived design improvement proposal to the multifunctional automatic lathe bed, 57.4% weight reduction and maximum principal stress decreased by 45.0% than the initial design model. It is expected that the optimum design that meets these design conditions will reduce the weight of the structure as well as improve the safety of the structure and reduce the machining error in the operation of the machine tool.

Emodin Attenuates Inflammasome Activation Induced by Helicobacter pylori Infection through Inhibition of VacA Translocation

  • Thach Phan Van;Anh Duy Do
    • Microbiology and Biotechnology Letters
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    • v.51 no.4
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    • pp.507-516
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    • 2023
  • Eradication of Helicobacter pylori infection is an essential strategy to decrease the risk of developing gastric cancer. However, the standard triple therapy has negative aspects associated with side effects and the emergence of antibiotic resistance. Therefore, alternative therapies are required to enhance the management of H. pylori infection effectively. In this study we examined the effect of emodin on the amelioration of inflammatory response due to H. pylori infection. Our results indicated that emodin treatment effectively decreased the expression of virulence genes, including sabA, vacA, cagL, cagA, sabA, and suppressed the adhesion ability of H. pylori to AGS cells. Emodin has been shown inhibitory effects on the inflammasome pathway through reductions in VacA translocation, lowering ROS stress, cleaved Caspase-1, NLRP3, and cleaved Gasdermin D levels, thereby lowered pyroptosis in infected cells. In summary, our study demonstrated that emodin has the ability to attenuate inflammation caused by H. pylori by modulating virulence gene expression and decreasing VacA translocation. Further study is required to evaluate the therapeutic efficacy of emodin in treating H. pylori infection and better understand the underlying mechanisms.

Design of a VCM actuator for dual servo system

  • Choi, Hyeun-Seok;Han, Chang-Soo;Kim, Seung-Soo;Kim, Eung-Zu;Choi, Tae-Hoon;Na, Kyoung-Hwan
    • 제어로봇시스템학회:학술대회논문집
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    • 2004.08a
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    • pp.301-306
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    • 2004
  • In this study, Dual servo mechanism with VCM(Voice Coil Motor) and PZT is designed for a high precision force and position control. We designed the VCM actuator and dual servo mechanism with leaf spring. VCM actuators, with their high linearity, simple structure, low weight, and high efficiency, are increasingly being used in micro-positioning applications. There are many kinds of VCM with a structure. VCM actuators are divided into two types by moving parts. One is moving magnet type and the other moving coil type. We described the properties of these two types of VCM. Design parameters of VCM are defined through the FEM simulation analysis of magnetic field and dynamic model of dual servo mechanism. These researches help to for decreasing loss in the air gap of VCM. We present dual servo mechanism is effective mechanism for a force control in hi h precision, properties of designed VCM.

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Plant biotech research and development for agribusiness in Jeju

  • Song, Pill-Soon
    • Proceedings of the Korean Society of Plant Biotechnology Conference
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    • 2005.11a
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    • pp.84-87
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    • 2005
  • The citrus industry represents a major sector of agribusiness in Jeju successfully nurtured by the local governmental farm bureaus for the past three decades. However, in the face of increasing imports effected under the international free trade agreement, the continuous economic viability of the island’s citrus industry is no longer assured. Thus, it entails exploration and development of new agribusiness potentials that are supplemental and/or alternative to the citrus industry. In this presentation, I will discuss two projects of such potentials. (i) Under the tripartite collaboration among Kumho Life and Environmental Science Laboratory, Cheju National University and South Jeju County, genetically engineered turfgrass cultivars possessing both herbicide- and shade-tolerances (gene pyramiding) are currently at final phase of phenotype evaluations and environmental safety assessments. (ii) Fig fruits with longer shelf-life are being developed with support from Jeju HiTech Industrial Development Institute (HiDI) and at its initial phase of development.

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Comparison of the MGISEQ-2000 and Illumina HiSeq 4000 sequencing platforms for RNA sequencing

  • Jeon, Sol A;Park, Jong Lyul;Kim, Jong-Hwan;Kim, Jeong Hwan;Kim, Yong Sung;Kim, Jin Cheon;Kim, Seon-Young
    • Genomics & Informatics
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    • v.17 no.3
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    • pp.32.1-32.6
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    • 2019
  • Currently, Illumina sequencers are the globally leading sequencing platform in the next-generation sequencing market. Recently, MGI Tech launched a series of new sequencers, including the MGISEQ-2000, which promise to deliver high-quality sequencing data faster and at lower prices than Illumina's sequencers. In this study, we compared the performance of two major sequencers (MGISEQ-2000 and HiSeq 4000) to test whether the MGISEQ-2000 sequencer delivers high-quality sequence data as suggested. We performed RNA sequencing of four human colon cancer samples with the two platforms, and compared the sequencing quality and expression values. The data produced from the MGISEQ-2000 and HiSeq 4000 showed high concordance, with Pearson correlation coefficients ranging from 0.98 to 0.99. Various quality control (QC) analyses showed that the MGISEQ-2000 data fulfilled the required QC measures. Our study suggests that the performance of the MGISEQ-2000 is comparable to that of the HiSeq 4000 and that the MGISEQ-2000 can be a useful platform for sequencing.

A Study on Policy Directions for Regional Development of North Korea (북한 지역개발 방향에 대한 연구)

  • Lee, Sang-Jun
    • Land and Housing Review
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    • v.6 no.2
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    • pp.101-106
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    • 2015
  • In order to minimize regional disparities between the North and the South, it is very important to reduce shortages of food and energy in North Korea in the short and mid-term. In the long term, it is important to reduce not only regional disparities between two Koreas but also regional disparities in North Korea. It is important to consider national policies of the North, the South and other countries in Northeast Asia in the process of building regional development policies for North Korea because the future of regional development in North Korea depends on policies of stakeholder in Northeast Asia. This study suggest some policy directions for regional development in North Korea. At first, building new industries, such as hi-tech industries and MICE, is important for regional development potentials in North Korea. Also, we should take some special development strategies according to regional potentials in North Korea. For example, Nampo region should be specialized through hi-tech industries. Wonsan region should be specialized through MICE. Finally, this study suggests some policy issues to the South Korean government. Financial support from South Korean government about inter-Korean economic cooperation should have priorities on the regions where have potentials of hi-tech industries and MICE. Also, we should implement inter-Korean economic cooperation policies under consideration about spatial aspects.

Wind loads and load-effects of large scale wind turbine tower with different halt positions of blade

  • Ke, Shitang;Yu, Wei;Wang, Tongguang;Zhao, Lin;Ge, Yaojun
    • Wind and Structures
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    • v.23 no.6
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    • pp.559-575
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    • 2016
  • In order to investigate the influence of different blade positions on aerodynamic load and wind loads and load-effects of large scale wind turbine tower under the halt state, we take a certain 3 MW large scale horizontal axis three-blade wind turbine as the example for analysis. First of all, numerical simulation was conducted for wind turbine flow field and aerodynamic characteristics under different halt states (8 calculating conditions in total) based on LES (large eddy simulation) method. The influence of different halt states on the average and fluctuating wind pressure coefficients of turbine tower surface, total lift force and resistance coefficient, circular flow and wake flow characteristics was compared and analysed. Then on this basis, the time-domain analysis of wind loads and load-effects was performed for the wind turbine tower structure under different halt states by making use of the finite element method. The main conclusions of this paper are as follows: The halt positions of wind blade could have a big impact on tower circular flow and aerodynamic distribution, in which Condition 5 is the most unfavourable while Condition 1 is the most beneficial condition. The wind loads and load-effects of disturbed region of tower is obviously affected by different halt positions of wind blades, especially the large fluctuating displacement mean square deviation at both windward and leeward sides, among which the maximum response occurs in $350^{\circ}$ to the tower top under Condition 8; the maximum bending moment of tower bottom occurs in $330^{\circ}$ under Condition 2. The extreme displacement of blade top all exceeds 2.5 m under Condition 5, and the maximum value of windward displacement response for the tip of Blade 3 under Condition 8 could reach 3.35 m. All these results indicate that the influence of halt positions of different blades should be taken into consideration carefully when making wind-resistance design for large scale wind turbine tower.

Separation and Recovery of Tin and Indium from Spent ITO Sludge (폐 ITO 슬러지로부터 주석과 인듐의 분리·회수)

  • Lee, Ki-Woong;Kim, Hong-In;Son, Hyun-Tae;Ahn, Jae-Woo;Kim, Yong-Hwan
    • Resources Recycling
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    • v.23 no.2
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    • pp.53-60
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    • 2014
  • In order to separate Indium and Tin from spent indium tin oxide (ITO) sludge, direct hydrochloric acid leaching and thermal reduction followed by HCl leaching were applied. In case of direct leaching of spent ITO, leaching rate of In and Sn was 18.5% and 19.95%, respectively. Whereas, in case of thermal hydrogen treatment of ITO sludge at different temperatures such as $700^{\circ}C$, $800^{\circ}C$, $900^{\circ}C$ and $1100^{\circ}C$, followed by HCl leaching, we obtained the result of more than 97% leaching rate of Sn. Specially, thermal treatment at $800^{\circ}C$ showed the highest leaching rate of 98.2% of Sn. Precipitation method was used for separation and recovery of Sn from leached mixed solution. If the solution pH were adjusted 2.0, 99.69% of Sn precipitated and 10.3% of In was precipitated. This confirmed the possibility of separation of Sn and In from leached solution by precipitation method.

Produce of High Purity Tin from Spent Solder by Electro Refining (폐 솔더 잉곳으로부터 전해정련에 의한 고순도 주석 생산)

  • Lee, Ki-Woong;Kim, Hong-In;Ahn, Hyo-Jin;Ahn, Jae-Woo;Son, Seong-Ho
    • Resources Recycling
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    • v.24 no.2
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    • pp.62-68
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    • 2015
  • The high pure tin production was conducted from crude-tin containing waste solder by electro-refining process. The electro-refining process maintained at 0.2V produced tin with purity of 99.98%, whereas a little increase of voltage to 0.3 V resulted tin purity of 99.92%. The high pure tin of 3N in the present process was produced by fixing the voltage at 0.3V. Considering the high pure tin production, the current density was maintained within $100-120A/m^2$ with current efficiency of 94%. Addition of sulfuric acid of 20 ~ 25 g/L to the electrolyte solution was performed in order to keep Pb (lead) concentration below 100 mg/L in the final tin product. The anode slime generated during electro refining process was analyzed by X-ray diffraction (XRD) study to understand the phases of impurities in it. It detected the presence of Cu and Ag in the slime as in the form of $Cu_6Sn_5$, $Ag_3Sn$, whereas Pb occurred as $PbSO_4$ compound.

Computer Ethics in Computer Education (컴퓨터 윤리에 관한 연구)

  • Joo, Young-Ju;Lee, Kwang-Hi
    • Journal of The Korean Association of Information Education
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    • v.1 no.2
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    • pp.84-100
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    • 1997
  • All technology has both intended and unintended effects, we have said, and information technology is no exception. Information technology offers a number of challenges: those of computer education, computer literacy, the ethical and societal impacts of computing and communication systems. Current computer education focuses primarily on the history, parts and usage of a computer, and programming, it does not fully include the moral standards or ethics that help guide behavior and conduct for citizens of Information society. The purpose of this study is to review of the theoretical issues and societal impacts of computers, communication systems and computer ethics; then, to nalyse current curriculum and content of school computer education in Korea: finally, to develop a possible course in computer ethics containing a goal statement and aspects of computer literacy. Contents in computer ethics covers issues of nettiquette, privacy, health, copyright-related software and network piracy, computer crime and viruses. Six suggestions are made for the computer ethics of Information Age in the conclusion.

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