• BMB Reports
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• v.32 no.2
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• pp.103-111
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• 1999

Hh proteins represent a new signaling paradigm in metazoan development. In species ranging from fruit flies to humans, Hh proteins mediate multiple processes vital to appropriate pattern formation in the developing embryo. Hh proteins undergo an autoprocessing event in which the full-length protein is cleaved into N-terminal and C-terminal domains (Hh-N and Hh-C, respectively), and a cholesterol moiety becomes covalently attached to Hh-N. All known signaling activities of Hh proteins are mediated by Hh-N while both the cleavage and cholesterol transfer reactions are mediated by Hh-C. The cholesterol attached to Hh-N is required to retrict the range of Hh signaling and may be involved in ensuring appropriate reception of the Hh signal in target tissues. Disruptions of Hh signaling pathways lead to severe developmental defects in newborns and cancers in adults. While studies of Hh proteins have yielded a wealth of new insight into the molecular mechanisms of metazoan development, many outstanding questions concerning Hh signaling mechanisms ensure that unraveling the secrets of this molecule will keep scientists well entertained for the foreseeable future.

• Korean Journal of Applied Biomechanics
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• v.29 no.3
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• pp.197-204
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• 2019

Objective: The purpose of this study was to identify the effect of high-heels (HH) modification on metatarsal stress in female workers. Method: Seven females who work in clothing stores ($heights=160.4{\pm}3.9cm$; $weights=47.4{\pm}4.1kg$; $age=31.3{\pm}11.1yrs$; $HH\;wear\;career=8{\pm}6.5yrs$) wore two types of HH (original and modified). The modified HH had been grooved with 1.5 cm radius and 0.2 cm depth around the first metatarsal area inside of the shoes using the modified shoe-last. Participants were asked to walk for 15 minutes on a treadmill and to stand for 10 minutes with original and modified HH, respectively. Kinetics data were collected by the F-scan in-shoe system. After each test, participants were asked to rate their perceived exertion using the Borg's 15-grade RPE scale and interviewed about their feeling of HH. Nonparametric Wilcoxon signed-rank test and effect size (Cohen's d) were used to determine the difference of the variables of interest between the original and modified HH. Results: In the present study, modified HH of the peak contact pressure of 1st metatarsal (PCP) left, PCP right, pressure time integral (PTI) left, peak pressure gradient (PPG) left during standing and PPG right during walking are greater than original HH. And even it didn't show statistically significant, the average in all pressure values of modified HH showed bigger than original HH. It surmised to be related to awkward with modified HH. Even though they said to feel the comfortable cause of big space inside of HH in the interview, they seemed to be not enough time to adapt with new HH. So their walking and standing postures were unstable. Conclusion: Modified the fore-medial part of HH can reduce the stress in the first metatarsal head and big toe area during standing and walking.

• The Korean Journal of Quaternary Research
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• v.17 no.2
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• pp.169-170
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• 2003

The existence of coastal terraces, HH(High higher) surfaces found at Gampo of southeast coast and at Jeongdongjin of the central east coast were confirmed at Jigyeong-Ri, the areal border between Gyeongju- and Ulsan city on the southeast coast of Korea Peninsula. Especially this study reports HH JK-surface located on the 155m a.s.l., which is the highest altitude among the ancient shorelines of the coastal terraces in Korea. The HH surfaces on the study area are classified into HH JK at 155m, HH-I at 140m and HH-II at 115m, and each formation stage is related to MIS 17(720∼690ka BP), MIS 15(630∼560ka BP) and MIS 13(510∼480ka BP) respectively. The HH-surfaces remain to be larger than those of H- and L-surfaces. The reason is caused by the unique factors of the coastal geology and morphology on the study area during the formation stage. And also the areal difference by the magnitude of upheaval doesn't exist from north to south because the altitude system of ancient shoreline on each coastal terrace is same along the east coast. The upheaval rate of the eastern coastal areas was measured in the relation to the ancient shoreline and formation stage among the coastal terraces such as HH JK-, HH-I, HH-II, H-III and H-IY surface, and was almost same as 0.23mm/y.

• Phonetics and Speech Sciences
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• v.6 no.4
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• pp.53-65
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• 2014

The current research examines whether pitch contour shapes in North Kyungsang pitch accent contrasts provide a phonetic dimension for phonological discreteness in a mimicry task. Two pitch accent continua resynthesized were created for HH vs. HL and HH vs. LH. To confirm a phonetic dimension for accounting for pitch accent categories in North Kyungsang Korean, the mimicries of speakers of two dialects (i.e., North Kyungsang & South Cholla) were compared. One of the findings showed that, for North Kyungsang speakers, the range of mean f0 peak times was a phonetic dimension undergoing a continuous shift within a stimulus continuum for both HH vs. HL and HH vs. LH. On the other hand, for South Cholla speakers, there were no apparent shifts around categorical boundaries for either HH vs. HL or HH vs. LH. Regarding individual mimicries on f0 peak timing, there are many variations. For HH vs. LH, three North Kyungsang speakers showed a discrete pattern reflecting a shift in phonological categories, but for HH vs. HL, there was no such distinction showing a categorical shift, though there were statistically significant differences for two speakers. Interestingly, one of the North Kyungsang speakers showed a continuous phonetic dimension for both HH vs. HL and HH vs. LH. Lastly, the f0 valley timing did not exhibit a discrete or gradient phonetic dimension for speakers of either dialect. On the basis of these results, what is interesting is that the tonal target such as high tone in North Kyungsang pitch accent categories within the autosegmental-metrical (AM) theory may be realized within individual cognitive systems for representing the interaction of perception and production.

• Research in Community and Public Health Nursing
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• v.30 no.1
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• pp.99-107
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• 2019

Purpose: This study aimed to assess hand hygiene (HH) compliance among visitors at a long-term care hospital in South Korea. Methods: The study was conducted at a 502-bed long-term care hospital located in Gyeonggi-do Province. From July 1 to August 15, 2017, including more than 6 weekends and one holiday, a trained observer covertly assessed visitors' HH at all five units (360 beds in total) of the study hospital building until the completion of 1,000 HH opportunities (i.e., 200 opportunities per unit). The modified World Health Organization (WHO) HH observation form was used. Instead of professional categories and the "before clean/aseptic procedure" moment, the estimated age range for each visitor were recorded in four categories: children (<14 years old), adolescents (14~18), adults (19~64), and the elderly (${\geq}65$). The collected data were analyzed using SPSS 22.0. Results: A total of 1,000 HH opportunities were observed from 766 visitors (an average of 1.31 per visitor) and the overall HH compliance rate was 20.3%. Overall, 53.7% of the HH cases were performed with soap and water. Among the 4 HH moments, the "after body fluid exposure risk" moment showed the highest compliance rate (83.5%); 93.9% used soap and water. The most commonly exposed potential body fluid among visitors was saliva (48.1%). Conclusion: For hospital visitors in long-term care hospitals, HH education programs including HH moments need to be developed and implemented. Further studies are necessary to evaluate visitors' HH compliance in various hospital settings and find the related variables influencing visitors' HH.

• Proceedings of the KSME Conference
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• 2001.11a
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• pp.527-532
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• 2001

In this paper, we will propose the new method that estimates the sensing ability of HH smart sensor. We have developed a new signal processing method that can distinguish among different materials relatively. The HH smart sensor was developed for recognition of materials. We made the HH smart sensor in our experiment. Then, we estimated the ability to recognize objects according to acceleration value. We estimated the sensing ability of HH smart sensor with the $R_{SAI}$ method. Experiments and analysis were executed to estimate the ability to recognize objects according to acceleration value changing. Dynamic characteristics of HH smart sensor were evaluated relatively through a new $R_{SAI}$ method that uses the power spectrum density. Applications of this method are for finding abnormal conditions of objects (auto-manufacturing), feeling of objects (medical product), robotics, safety diagnosis of structure, etc.

• Transactions of the Korean Society of Machine Tool Engineers
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• v.13 no.1
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• pp.22-27
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• 2004

A new method that estimates the sensing ability of HH smart sensor is proposed. The new signal processing method have been developed that can distinguish among different materials relatively. The HH smart sensor was developed far recognition of materials. The HH smart sensor was made for experiment. Then, it was estimated the ability to recognize objects according to acceleration value. The sensing ability of HH smart sensor has been estimated with the $R_{SAI}$ method. Experiments and analysis were executed to estimate the ability to recognize objects according to acceleration value changing. Dynamic characteristics of HH smart sensor were evaluated relatively through a new $R_{SAI}$ method that uses the power spectrum density. Applications of this method are for finding abnormal conditions of objects (auto-manufacturing), feeling of objects (medical product), robotics, safety diagnosis of structure, etc.

• Journal of the Korean Geographical Society
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• v.38 no.4
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• pp.490-504
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• 2003

The existence of coastal terraces, HH(High higher) surfaces found at Gampo of southeast coast and at Jeongdongjin of the central east coast were confirmed at Jjgyeong-Ri, the areal border between Gyeongjuand Ulsan city on the southeast coast of Korea Peninsula. Especially this study reports HH JK-surface located on the 155m a.s.l, which is the highest altitude among the ancient shorelines of the coastal terraces in Korea. The HH surfaces on the study area are classified into HH JK at 155m, HH I at 140m and HH II at 115m, and each formation stage is related to MIS 17(720∼690ka BP), MIS 15(630∼560ka BP) and MIS 13(510∼480ka BP) respectively. The HH-surfaces remain to be larger than those of H- and L-surfaces. The reason is caused by the unique factors of the coastal geology and morphology on the study area during the formation stage. And also the areal difference by the magnitude of upheaval doesn't exist from north to south because the altitude system of ancient shoreline on each coastal terrace is same along the east coast. The upheaval rate of the eastern coastal areas was measured in the relation to the ancient shoreline and formation stage among the coastal terraces such as HH JK-, HH I-, HH II, H I- and H II surface, and was almost same as 0.23mm/y.

• Perspectives in Nursing Science
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• v.12 no.1
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• pp.7-13
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• 2015

Purpose: This observational study was aimed to determine the influence of the Hawthorne effect on the adherence to hand hygiene (HH) among healthcare workers (HCWs) in South Korea. Methods: HCWs were monitored in 2 periods regarding adherence to HH when there were indications for HH. In first period, HCWs recognized that their behavior of hand hygiene being observed (overt observation), and did not recognize in second period (covert observation). Results: The overall difference in HH rate between two periods was 45.0% point (77.8% vs 32.8%). There were significant differences between profession but in nurse aids. The differences in HH rate between two periods were 46.1% point in nurses, 29.9% point in physicians, 64.0% in radiologists, 62.5% point in laboratory technicians, 36.4% point in physio-therapist, and 1.0% point in nurse aids. The Hawthorne effect on the adherence to HH lasted more than 3 months. Conclusion: The Hawthorne effect markedly influence on the adherence to HH regardless of profession except nurse aids. Therefore, Hawthorne effect can be useful tool to improve and sustain the adherence to HH among HCWs in South Korea.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.69.1-69.1
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• 2015

Classical T Tauri star DG Tau is suggested as the driving source of parsec-scale jet which expands up to 650" (0.4 pc). To investigate the kinematics and physical properties of the jet, we have obtained the optical emission lines of $H{\alpha}$, [O I] ${\lambda}{\lambda}$6300, 6363, [N II] ${\lambda}{\lambda}$6548,6584, and [S II] ${\lambda}{\lambda}$6716, 6731 from HH 158 ad HH 702. The radial velocity of HH 158 is in the range of -50 to $-250km\;s^{-1}$. For HH 702, located at 650" from the source, it shows ~ $-80km\;s^{-1}$. In HH 158, the electron density ($n_e$) close to the star is ${\sim}10^4cm^{-3}$ and it decreases to ${\sim}10^2cm^{-3}$ at 14" away from the star. Electron temperature ($T_e$) is decreasing from >15,000 K to ~5,000 K with distance. Ionization fraction ($x_e$) is increasing from almost zero to > 0.4 along the distance. In HH 702, the values of $n_e$, $T_e$, and $x_e$ are similar to those estimated at 14" from source, where knot C of HH 158 is located. This may imply that the physical properties of the knot could persist through such a long distance in the space, and the gas could be re-excited by the shock during propagation of the jet. On the other hand, we cannot avoid the possibility that HH 702 is driven by another source rather than DG Tau because HH 158 and HH 702 show somewhat large difference in their inclination angles (${\Delta}i=21-35^{\circ}$).